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Rheumatoid factors from patients with rheumatoid arthritis react with tryptophan 60 and 95, lysine 58, and arginine 97, on human beta 2-microglobulin.

Identifieur interne : 002915 ( Ncbi/Curation ); précédent : 002914; suivant : 002916

Rheumatoid factors from patients with rheumatoid arthritis react with tryptophan 60 and 95, lysine 58, and arginine 97, on human beta 2-microglobulin.

Auteurs : R C Williams ; C C Malone ; J B Harley

Source :

RBID : pubmed:7686371

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English descriptors

Abstract

To define precise epitopes on human beta 2-microglobulin (beta 2m) reacting with polyclonal IgM rheumatoid factors (RF) from patients with rheumatoid arthritis (RA).

DOI: 10.1002/art.1780360708
PubMed: 7686371

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R C Williams
<affiliation>
<nlm:affiliation>Department of Medicine, University of Florida College of Medicine, Gainesville 32610.</nlm:affiliation>
<wicri:noCountry code="subField">Gainesville 32610</wicri:noCountry>
</affiliation>

Le document en format XML

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<title xml:lang="en">Rheumatoid factors from patients with rheumatoid arthritis react with tryptophan 60 and 95, lysine 58, and arginine 97, on human beta 2-microglobulin.</title>
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<nlm:affiliation>Department of Medicine, University of Florida College of Medicine, Gainesville 32610.</nlm:affiliation>
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<title xml:lang="en">Rheumatoid factors from patients with rheumatoid arthritis react with tryptophan 60 and 95, lysine 58, and arginine 97, on human beta 2-microglobulin.</title>
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<affiliation>
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<term>Amino Acid Sequence</term>
<term>Antibody Specificity</term>
<term>Arginine (analysis)</term>
<term>Arthritis, Rheumatoid (blood)</term>
<term>Arthritis, Rheumatoid (immunology)</term>
<term>Aspartic Acid (analysis)</term>
<term>Chromatography, Affinity</term>
<term>Computers</term>
<term>Epitopes (analysis)</term>
<term>Humans</term>
<term>Immunoglobulin A (chemistry)</term>
<term>Immunoglobulin A (immunology)</term>
<term>Immunoglobulin Fc Fragments (analysis)</term>
<term>Immunoglobulin G (chemistry)</term>
<term>Immunoglobulin G (immunology)</term>
<term>Immunoglobulin M (chemistry)</term>
<term>Immunoglobulin M (immunology)</term>
<term>Isoleucine (analysis)</term>
<term>Lysine (analysis)</term>
<term>Molecular Sequence Data</term>
<term>Rheumatoid Factor (analysis)</term>
<term>Rheumatoid Factor (immunology)</term>
<term>Sequence Homology, Amino Acid</term>
<term>Tryptophan (analysis)</term>
<term>Valine (analysis)</term>
<term>beta 2-Microglobulin (chemistry)</term>
<term>beta 2-Microglobulin (immunology)</term>
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<term>Acide aspartique (analyse)</term>
<term>Arginine (analyse)</term>
<term>Chromatographie d'affinité</term>
<term>Données de séquences moléculaires</term>
<term>Facteur rhumatoïde (analyse)</term>
<term>Facteur rhumatoïde (immunologie)</term>
<term>Fragments Fc des immunoglobulines (analyse)</term>
<term>Humains</term>
<term>Immunoglobuline A ()</term>
<term>Immunoglobuline A (immunologie)</term>
<term>Immunoglobuline G ()</term>
<term>Immunoglobuline G (immunologie)</term>
<term>Immunoglobuline M ()</term>
<term>Immunoglobuline M (immunologie)</term>
<term>Isoleucine (analyse)</term>
<term>Lysine (analyse)</term>
<term>Ordinateurs</term>
<term>Polyarthrite rhumatoïde (immunologie)</term>
<term>Polyarthrite rhumatoïde (sang)</term>
<term>Similitude de séquences d'acides aminés</term>
<term>Spécificité des anticorps</term>
<term>Séquence d'acides aminés</term>
<term>Tryptophane (analyse)</term>
<term>Valine (analyse)</term>
<term>bêta-2-Microglobuline ()</term>
<term>bêta-2-Microglobuline (immunologie)</term>
<term>Épitopes (analyse)</term>
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<term>Arginine</term>
<term>Aspartic Acid</term>
<term>Epitopes</term>
<term>Immunoglobulin Fc Fragments</term>
<term>Isoleucine</term>
<term>Lysine</term>
<term>Rheumatoid Factor</term>
<term>Tryptophan</term>
<term>Valine</term>
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<term>Acide aspartique</term>
<term>Arginine</term>
<term>Facteur rhumatoïde</term>
<term>Fragments Fc des immunoglobulines</term>
<term>Isoleucine</term>
<term>Lysine</term>
<term>Tryptophane</term>
<term>Valine</term>
<term>Épitopes</term>
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<term>Arthritis, Rheumatoid</term>
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<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en">
<term>Immunoglobulin A</term>
<term>Immunoglobulin G</term>
<term>Immunoglobulin M</term>
<term>beta 2-Microglobulin</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr">
<term>Facteur rhumatoïde</term>
<term>Immunoglobuline A</term>
<term>Immunoglobuline G</term>
<term>Immunoglobuline M</term>
<term>Polyarthrite rhumatoïde</term>
<term>bêta-2-Microglobuline</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en">
<term>Arthritis, Rheumatoid</term>
<term>Immunoglobulin A</term>
<term>Immunoglobulin G</term>
<term>Immunoglobulin M</term>
<term>Rheumatoid Factor</term>
<term>beta 2-Microglobulin</term>
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<keywords scheme="MESH" qualifier="sang" xml:lang="fr">
<term>Polyarthrite rhumatoïde</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Amino Acid Sequence</term>
<term>Antibody Specificity</term>
<term>Chromatography, Affinity</term>
<term>Computers</term>
<term>Humans</term>
<term>Molecular Sequence Data</term>
<term>Sequence Homology, Amino Acid</term>
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<keywords scheme="MESH" xml:lang="fr">
<term>Chromatographie d'affinité</term>
<term>Données de séquences moléculaires</term>
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<term>Immunoglobuline A</term>
<term>Immunoglobuline G</term>
<term>Immunoglobuline M</term>
<term>Ordinateurs</term>
<term>Similitude de séquences d'acides aminés</term>
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<div type="abstract" xml:lang="en">To define precise epitopes on human beta 2-microglobulin (beta 2m) reacting with polyclonal IgM rheumatoid factors (RF) from patients with rheumatoid arthritis (RA).</div>
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