SigHunt: horizontal gene transfer finder optimized for eukaryotic genomes.
Identifieur interne : 000C40 ( Ncbi/Curation ); précédent : 000C39; suivant : 000C41SigHunt: horizontal gene transfer finder optimized for eukaryotic genomes.
Auteurs : Kamil S. Jaron [République tchèque] ; Ji C. Moravec [République tchèque] ; Natália Martínková [République tchèque]Source :
- Bioinformatics (Oxford, England) [ 1367-4811 ] ; 2014.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- genetics : Eukaryota.
- methods : Genomics, Sequence Analysis, DNA.
- Base Composition, Computational Biology, Gene Transfer, Horizontal, Genomic Islands, Phylogeny.
Abstract
Genomic islands (GIs) are DNA fragments incorporated into a genome through horizontal gene transfer (also called lateral gene transfer), often with functions novel for a given organism. While methods for their detection are well researched in prokaryotes, the complexity of eukaryotic genomes makes direct utilization of these methods unreliable, and so labour-intensive phylogenetic searches are used instead.
DOI: 10.1093/bioinformatics/btt727
PubMed: 24371153
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pubmed:24371153Le document en format XML
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<term>Genomics (methods)</term>
<term>Phylogeny</term>
<term>Sequence Analysis, DNA (methods)</term>
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<term>Biologie informatique</term>
<term>Composition en bases nucléiques</term>
<term>Eucaryotes (génétique)</term>
<term>Génomique ()</term>
<term>Ilots génomiques</term>
<term>Phylogénie</term>
<term>Transfert horizontal de gène</term>
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<front><div type="abstract" xml:lang="en">Genomic islands (GIs) are DNA fragments incorporated into a genome through horizontal gene transfer (also called lateral gene transfer), often with functions novel for a given organism. While methods for their detection are well researched in prokaryotes, the complexity of eukaryotic genomes makes direct utilization of these methods unreliable, and so labour-intensive phylogenetic searches are used instead.</div>
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