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Serological detection of attenuated HIV-1 variants with nef gene deletions.

Identifieur interne : 002B15 ( Ncbi/Checkpoint ); précédent : 002B14; suivant : 002B16

Serological detection of attenuated HIV-1 variants with nef gene deletions.

Auteurs : A L Greenway [Australie] ; J. Mills ; D. Rhodes ; N J Deacon ; D A Mcphee

Source :

RBID : pubmed:9583594

Descripteurs français

English descriptors

Abstract

To investigate whether members of a transfusion-linked cohort (the Sydney Bloodbank Cohort) infected with a nef-deleted strain of HIV-1 could be differentiated from individuals infected with wild-type strains of HIV-1 by characterizing the Nef antibody response of cohort members.

DOI: 10.1097/00002030-199806000-00003
PubMed: 9583594


Affiliations:


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pubmed:9583594

Le document en format XML

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<title xml:lang="en">Serological detection of attenuated HIV-1 variants with nef gene deletions.</title>
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<name sortKey="Greenway, A L" sort="Greenway, A L" uniqKey="Greenway A" first="A L" last="Greenway">A L Greenway</name>
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<nlm:affiliation>AIDS Cellular Biology Unit, National Centre in HIV Virology Research, Macfarlane Burnet Centre for Medical Research, Fairfield, Victoria, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>AIDS Cellular Biology Unit, National Centre in HIV Virology Research, Macfarlane Burnet Centre for Medical Research, Fairfield, Victoria</wicri:regionArea>
<wicri:noRegion>Victoria</wicri:noRegion>
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<name sortKey="Mills, J" sort="Mills, J" uniqKey="Mills J" first="J" last="Mills">J. Mills</name>
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<name sortKey="Rhodes, D" sort="Rhodes, D" uniqKey="Rhodes D" first="D" last="Rhodes">D. Rhodes</name>
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<name sortKey="Deacon, N J" sort="Deacon, N J" uniqKey="Deacon N" first="N J" last="Deacon">N J Deacon</name>
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<name sortKey="Mcphee, D A" sort="Mcphee, D A" uniqKey="Mcphee D" first="D A" last="Mcphee">D A Mcphee</name>
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<term>AIDS Serodiagnosis (methods)</term>
<term>Cohort Studies</term>
<term>Enzyme-Linked Immunosorbent Assay (methods)</term>
<term>Epitope Mapping</term>
<term>Evolution, Molecular</term>
<term>Gene Products, nef</term>
<term>Genes, nef (genetics)</term>
<term>HIV Antibodies (blood)</term>
<term>HIV Seropositivity (immunology)</term>
<term>HIV Seropositivity (virology)</term>
<term>HIV-1 (genetics)</term>
<term>HIV-1 (immunology)</term>
<term>Humans</term>
<term>Peptides (chemical synthesis)</term>
<term>Prospective Studies</term>
<term>Recombinant Proteins</term>
<term>Retrospective Studies</term>
<term>Sequence Deletion (genetics)</term>
<term>Sequence Deletion (immunology)</term>
<term>Survivors</term>
<term>Victoria</term>
<term>nef Gene Products, Human Immunodeficiency Virus</term>
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<keywords scheme="KwdFr" xml:lang="fr">
<term>Anticorps anti-VIH (sang)</term>
<term>Cartographie épitopique</term>
<term>Délétion de séquence (génétique)</term>
<term>Délétion de séquence (immunologie)</term>
<term>Gènes nef (génétique)</term>
<term>Humains</term>
<term>Peptides (synthèse chimique)</term>
<term>Produits du gène nef</term>
<term>Produits du gène nef du virus de l'immunodéficience humaine</term>
<term>Protéines recombinantes</term>
<term>Survivants</term>
<term>Sérodiagnostic du SIDA ()</term>
<term>Séropositivité VIH (immunologie)</term>
<term>Séropositivité VIH (virologie)</term>
<term>Test ELISA ()</term>
<term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (génétique)</term>
<term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1) (immunologie)</term>
<term>Victoria</term>
<term>Études de cohortes</term>
<term>Études prospectives</term>
<term>Études rétrospectives</term>
<term>Évolution moléculaire</term>
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<term>Peptides</term>
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<term>Gene Products, nef</term>
<term>Recombinant Proteins</term>
<term>nef Gene Products, Human Immunodeficiency Virus</term>
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<term>Victoria</term>
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<term>Genes, nef</term>
<term>HIV-1</term>
<term>Sequence Deletion</term>
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<term>Délétion de séquence</term>
<term>Gènes nef</term>
<term>VIH-1 (Virus de l'Immunodéficience Humaine de type 1)</term>
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<term>Séropositivité VIH</term>
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<term>HIV Seropositivity</term>
<term>HIV-1</term>
<term>Sequence Deletion</term>
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<term>AIDS Serodiagnosis</term>
<term>Enzyme-Linked Immunosorbent Assay</term>
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<term>Anticorps anti-VIH</term>
</keywords>
<keywords scheme="MESH" qualifier="synthèse chimique" xml:lang="fr">
<term>Peptides</term>
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<term>Séropositivité VIH</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en">
<term>HIV Seropositivity</term>
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<term>Cohort Studies</term>
<term>Epitope Mapping</term>
<term>Evolution, Molecular</term>
<term>Humans</term>
<term>Prospective Studies</term>
<term>Retrospective Studies</term>
<term>Survivors</term>
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<term>Cartographie épitopique</term>
<term>Humains</term>
<term>Produits du gène nef</term>
<term>Produits du gène nef du virus de l'immunodéficience humaine</term>
<term>Protéines recombinantes</term>
<term>Survivants</term>
<term>Sérodiagnostic du SIDA</term>
<term>Test ELISA</term>
<term>Victoria</term>
<term>Études de cohortes</term>
<term>Études prospectives</term>
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<div type="abstract" xml:lang="en">To investigate whether members of a transfusion-linked cohort (the Sydney Bloodbank Cohort) infected with a nef-deleted strain of HIV-1 could be differentiated from individuals infected with wild-type strains of HIV-1 by characterizing the Nef antibody response of cohort members.</div>
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<name sortKey="Deacon, N J" sort="Deacon, N J" uniqKey="Deacon N" first="N J" last="Deacon">N J Deacon</name>
<name sortKey="Mcphee, D A" sort="Mcphee, D A" uniqKey="Mcphee D" first="D A" last="Mcphee">D A Mcphee</name>
<name sortKey="Mills, J" sort="Mills, J" uniqKey="Mills J" first="J" last="Mills">J. Mills</name>
<name sortKey="Rhodes, D" sort="Rhodes, D" uniqKey="Rhodes D" first="D" last="Rhodes">D. Rhodes</name>
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