Surveillance of the Middle East respiratory syndrome (MERS) coronavirus (CoV) infection in healthcare workers after contact with confirmed MERS patients: incidence and risk factors of MERS-CoV seropositivity
Identifieur interne : 001729 ( Ncbi/Checkpoint ); précédent : 001728; suivant : 001730Surveillance of the Middle East respiratory syndrome (MERS) coronavirus (CoV) infection in healthcare workers after contact with confirmed MERS patients: incidence and risk factors of MERS-CoV seropositivity
Auteurs : C.-J. Kim ; W. S. Choi ; Y. Jung ; S. Kiem ; H. Y. Seol ; H. J. Woo ; Y. H. Choi ; J. S. Son ; K.-H. Kim ; Y.-S. Kim ; E. S. Kim ; S. H. Park ; J. H. Yoon ; S.-M. Choi ; H. Lee ; W. S. Oh ; S.-Y. Choi ; N.-J. Kim ; J.-P. Choi ; S. Y. Park ; J. Kim ; S. J. Jeong ; K. S. Lee ; H. C. Jang ; J. Y. Rhee ; B.-N. Kim ; J. H. Bang ; J. H. Lee ; S. Park ; H. Y. Kim ; J. K. Choi ; Y.-M. Wi ; H. J. ChoiSource :
- Clinical Microbiology and Infection [ 1198-743X ] ; 2016.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Coronavirus du syndrome respiratoire du Moyen-Orient (immunologie), Enquêtes de santé, Femelle, Humains, Incidence, Infections à coronavirus (immunologie), Infections à coronavirus (épidémiologie), Jeune adulte, Mâle, Personnel de santé, Sujet âgé, Surveillance de la population, Transmission de maladie infectieuse du patient au professionnel de santé (), Études séroépidémiologiques.
- MESH :
- immunologie : Coronavirus du syndrome respiratoire du Moyen-Orient, Infections à coronavirus.
- épidémiologie : Infections à coronavirus.
- Adolescent, Adulte, Adulte d'âge moyen, Enquêtes de santé, Femelle, Humains, Incidence, Jeune adulte, Mâle, Personnel de santé, Sujet âgé, Surveillance de la population, Transmission de maladie infectieuse du patient au professionnel de santé, Études séroépidémiologiques.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Coronavirus Infections (epidemiology), Coronavirus Infections (immunology), Female, Health Personnel, Health Surveys, Humans, Incidence, Infectious Disease Transmission, Patient-to-Professional (statistics & numerical data), Male, Middle Aged, Middle East Respiratory Syndrome Coronavirus (immunology), Population Surveillance, Seroepidemiologic Studies, Young Adult.
- MESH :
- epidemiology : Coronavirus Infections.
- immunology : Coronavirus Infections, Middle East Respiratory Syndrome Coronavirus.
- statistics & numerical data : Infectious Disease Transmission, Patient-to-Professional.
- Adolescent, Adult, Aged, Female, Health Personnel, Health Surveys, Humans, Incidence, Male, Middle Aged, Population Surveillance, Seroepidemiologic Studies, Young Adult.
Abstract
Given the mode of transmission of Middle East respiratory syndrome (MERS), healthcare workers (HCWs) in contact with MERS patients are expected to be at risk of MERS infections. We evaluated the prevalence of MERS coronavirus (CoV) immunoglobulin (Ig) G in HCWs exposed to MERS patients and calculated the incidence of MERS-affected cases in HCWs. We enrolled HCWs from hospitals where confirmed MERS patients had visited. Serum was collected 4 to 6 weeks after the last contact with a confirmed MERS patient. We performed an enzyme-linked immunosorbent assay (ELISA) to screen for the presence of MERS-CoV IgG and an indirect immunofluorescence test (IIFT) to confirm MERS-CoV IgG. We used a questionnaire to collect information regarding the exposure. We calculated the incidence of MERS-affected cases by dividing the sum of PCR-confirmed and serology-confirmed cases by the number of exposed HCWs in participating hospitals. In total, 1169 HCWs in 31 hospitals had contact with 114 MERS patients, and among the HCWs, 15 were PCR-confirmed MERS cases in study hospitals. Serologic analysis was performed for 737 participants. ELISA was positive in five participants and borderline for seven. IIFT was positive for two (0.3%) of these 12 participants. Among the participants who did not use appropriate personal protective equipment (PPE), seropositivity was 0.7% (2/294) compared to 0% (0/443) in cases with appropriate PPE use. The incidence of MERS infection in HCWs was 1.5% (17/1169). The seroprevalence of MERS-CoV IgG among HCWs was higher among participants who did not use appropriate PPE.
Url:
DOI: 10.1016/j.cmi.2016.07.017
PubMed: 27475739
PubMed Central: 7128923
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000B86
- to stream Pmc, to step Curation: 000B86
- to stream Pmc, to step Checkpoint: 000996
- to stream PubMed, to step Corpus: 001018
- to stream PubMed, to step Curation: 001018
- to stream PubMed, to step Checkpoint: 000E87
- to stream Ncbi, to step Merge: 001729
- to stream Ncbi, to step Curation: 001729
Links to Exploration step
PMC:7128923Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Surveillance of the Middle East respiratory syndrome (MERS) coronavirus (CoV) infection in healthcare workers after contact with confirmed MERS patients: incidence and risk factors of MERS-CoV seropositivity</title><author><name sortKey="Kim, C J" sort="Kim, C J" uniqKey="Kim C" first="C.-J." last="Kim">C.-J. Kim</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Choi, W S" sort="Choi, W S" uniqKey="Choi W" first="W. S." last="Choi">W. S. Choi</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Jung, Y" sort="Jung, Y" uniqKey="Jung Y" first="Y." last="Jung">Y. Jung</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Kiem, S" sort="Kiem, S" uniqKey="Kiem S" first="S." last="Kiem">S. Kiem</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Seol, H Y" sort="Seol, H Y" uniqKey="Seol H" first="H. Y." last="Seol">H. Y. Seol</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Woo, H J" sort="Woo, H J" uniqKey="Woo H" first="H. J." last="Woo">H. J. Woo</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Choi, Y H" sort="Choi, Y H" uniqKey="Choi Y" first="Y. H." last="Choi">Y. H. Choi</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Son, J S" sort="Son, J S" uniqKey="Son J" first="J. S." last="Son">J. S. Son</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Kim, K H" sort="Kim, K H" uniqKey="Kim K" first="K.-H." last="Kim">K.-H. Kim</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Kim, Y S" sort="Kim, Y S" uniqKey="Kim Y" first="Y.-S." last="Kim">Y.-S. Kim</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Kim, E S" sort="Kim, E S" uniqKey="Kim E" first="E. S." last="Kim">E. S. Kim</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Park, S H" sort="Park, S H" uniqKey="Park S" first="S. H." last="Park">S. H. Park</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Yoon, J H" sort="Yoon, J H" uniqKey="Yoon J" first="J. H." last="Yoon">J. H. Yoon</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Choi, S M" sort="Choi, S M" uniqKey="Choi S" first="S.-M." last="Choi">S.-M. Choi</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Lee, H" sort="Lee, H" uniqKey="Lee H" first="H." last="Lee">H. Lee</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Oh, W S" sort="Oh, W S" uniqKey="Oh W" first="W. S." last="Oh">W. S. Oh</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Choi, S Y" sort="Choi, S Y" uniqKey="Choi S" first="S.-Y." last="Choi">S.-Y. Choi</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Kim, N J" sort="Kim, N J" uniqKey="Kim N" first="N.-J." last="Kim">N.-J. Kim</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Choi, J P" sort="Choi, J P" uniqKey="Choi J" first="J.-P." last="Choi">J.-P. Choi</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Park, S Y" sort="Park, S Y" uniqKey="Park S" first="S. Y." last="Park">S. Y. Park</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Kim, J" sort="Kim, J" uniqKey="Kim J" first="J." last="Kim">J. Kim</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Jeong, S J" sort="Jeong, S J" uniqKey="Jeong S" first="S. J." last="Jeong">S. J. Jeong</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Lee, K S" sort="Lee, K S" uniqKey="Lee K" first="K. S." last="Lee">K. S. Lee</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Jang, H C" sort="Jang, H C" uniqKey="Jang H" first="H. C." last="Jang">H. C. Jang</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Rhee, J Y" sort="Rhee, J Y" uniqKey="Rhee J" first="J. Y." last="Rhee">J. Y. Rhee</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Kim, B N" sort="Kim, B N" uniqKey="Kim B" first="B.-N." last="Kim">B.-N. Kim</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Bang, J H" sort="Bang, J H" uniqKey="Bang J" first="J. H." last="Bang">J. H. Bang</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Lee, J H" sort="Lee, J H" uniqKey="Lee J" first="J. H." last="Lee">J. H. Lee</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Park, S" sort="Park, S" uniqKey="Park S" first="S." last="Park">S. Park</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Kim, H Y" sort="Kim, H Y" uniqKey="Kim H" first="H. Y." last="Kim">H. Y. Kim</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Choi, J K" sort="Choi, J K" uniqKey="Choi J" first="J. K." last="Choi">J. K. Choi</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Wi, Y M" sort="Wi, Y M" uniqKey="Wi Y" first="Y.-M." last="Wi">Y.-M. Wi</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Choi, H J" sort="Choi, H J" uniqKey="Choi H" first="H. J." last="Choi">H. J. Choi</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27475739</idno><idno type="pmc">7128923</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128923</idno><idno type="RBID">PMC:7128923</idno><idno type="doi">10.1016/j.cmi.2016.07.017</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000B86</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000B86</idno><idno type="wicri:Area/Pmc/Curation">000B86</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000B86</idno><idno type="wicri:Area/Pmc/Checkpoint">000996</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000996</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:27475739</idno><idno type="wicri:Area/PubMed/Corpus">001018</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001018</idno><idno type="wicri:Area/PubMed/Curation">001018</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001018</idno><idno type="wicri:Area/PubMed/Checkpoint">000E87</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000E87</idno><idno type="wicri:Area/Ncbi/Merge">001729</idno><idno type="wicri:Area/Ncbi/Curation">001729</idno><idno type="wicri:Area/Ncbi/Checkpoint">001729</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Surveillance of the Middle East respiratory syndrome (MERS) coronavirus (CoV) infection in healthcare workers after contact with confirmed MERS patients: incidence and risk factors of MERS-CoV seropositivity</title><author><name sortKey="Kim, C J" sort="Kim, C J" uniqKey="Kim C" first="C.-J." last="Kim">C.-J. Kim</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Choi, W S" sort="Choi, W S" uniqKey="Choi W" first="W. S." last="Choi">W. S. Choi</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Jung, Y" sort="Jung, Y" uniqKey="Jung Y" first="Y." last="Jung">Y. Jung</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Kiem, S" sort="Kiem, S" uniqKey="Kiem S" first="S." last="Kiem">S. Kiem</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Seol, H Y" sort="Seol, H Y" uniqKey="Seol H" first="H. Y." last="Seol">H. Y. Seol</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Woo, H J" sort="Woo, H J" uniqKey="Woo H" first="H. J." last="Woo">H. J. Woo</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Choi, Y H" sort="Choi, Y H" uniqKey="Choi Y" first="Y. H." last="Choi">Y. H. Choi</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Son, J S" sort="Son, J S" uniqKey="Son J" first="J. S." last="Son">J. S. Son</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Kim, K H" sort="Kim, K H" uniqKey="Kim K" first="K.-H." last="Kim">K.-H. Kim</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Kim, Y S" sort="Kim, Y S" uniqKey="Kim Y" first="Y.-S." last="Kim">Y.-S. Kim</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Kim, E S" sort="Kim, E S" uniqKey="Kim E" first="E. S." last="Kim">E. S. Kim</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Park, S H" sort="Park, S H" uniqKey="Park S" first="S. H." last="Park">S. H. Park</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Yoon, J H" sort="Yoon, J H" uniqKey="Yoon J" first="J. H." last="Yoon">J. H. Yoon</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Choi, S M" sort="Choi, S M" uniqKey="Choi S" first="S.-M." last="Choi">S.-M. Choi</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Lee, H" sort="Lee, H" uniqKey="Lee H" first="H." last="Lee">H. Lee</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Oh, W S" sort="Oh, W S" uniqKey="Oh W" first="W. S." last="Oh">W. S. Oh</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Choi, S Y" sort="Choi, S Y" uniqKey="Choi S" first="S.-Y." last="Choi">S.-Y. Choi</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Kim, N J" sort="Kim, N J" uniqKey="Kim N" first="N.-J." last="Kim">N.-J. Kim</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Choi, J P" sort="Choi, J P" uniqKey="Choi J" first="J.-P." last="Choi">J.-P. Choi</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Park, S Y" sort="Park, S Y" uniqKey="Park S" first="S. Y." last="Park">S. Y. Park</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Kim, J" sort="Kim, J" uniqKey="Kim J" first="J." last="Kim">J. Kim</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Jeong, S J" sort="Jeong, S J" uniqKey="Jeong S" first="S. J." last="Jeong">S. J. Jeong</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Lee, K S" sort="Lee, K S" uniqKey="Lee K" first="K. S." last="Lee">K. S. Lee</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Jang, H C" sort="Jang, H C" uniqKey="Jang H" first="H. C." last="Jang">H. C. Jang</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Rhee, J Y" sort="Rhee, J Y" uniqKey="Rhee J" first="J. Y." last="Rhee">J. Y. Rhee</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Kim, B N" sort="Kim, B N" uniqKey="Kim B" first="B.-N." last="Kim">B.-N. Kim</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Bang, J H" sort="Bang, J H" uniqKey="Bang J" first="J. H." last="Bang">J. H. Bang</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Lee, J H" sort="Lee, J H" uniqKey="Lee J" first="J. H." last="Lee">J. H. Lee</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Park, S" sort="Park, S" uniqKey="Park S" first="S." last="Park">S. Park</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Kim, H Y" sort="Kim, H Y" uniqKey="Kim H" first="H. Y." last="Kim">H. Y. Kim</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Choi, J K" sort="Choi, J K" uniqKey="Choi J" first="J. K." last="Choi">J. K. Choi</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Wi, Y M" sort="Wi, Y M" uniqKey="Wi Y" first="Y.-M." last="Wi">Y.-M. Wi</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author><author><name sortKey="Choi, H J" sort="Choi, H J" uniqKey="Choi H" first="H. J." last="Choi">H. J. Choi</name><affiliation><nlm:aff>NONE</nlm:aff></affiliation></author></analytic><series><title level="j">Clinical Microbiology and Infection</title><idno type="ISSN">1198-743X</idno><idno type="eISSN">1469-0691</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Coronavirus Infections (epidemiology)</term><term>Coronavirus Infections (immunology)</term><term>Female</term><term>Health Personnel</term><term>Health Surveys</term><term>Humans</term><term>Incidence</term><term>Infectious Disease Transmission, Patient-to-Professional (statistics & numerical data)</term><term>Male</term><term>Middle Aged</term><term>Middle East Respiratory Syndrome Coronavirus (immunology)</term><term>Population Surveillance</term><term>Seroepidemiologic Studies</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Coronavirus du syndrome respiratoire du Moyen-Orient (immunologie)</term><term>Enquêtes de santé</term><term>Femelle</term><term>Humains</term><term>Incidence</term><term>Infections à coronavirus (immunologie)</term><term>Infections à coronavirus (épidémiologie)</term><term>Jeune adulte</term><term>Mâle</term><term>Personnel de santé</term><term>Sujet âgé</term><term>Surveillance de la population</term><term>Transmission de maladie infectieuse du patient au professionnel de santé ()</term><term>Études séroépidémiologiques</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Coronavirus Infections</term><term>Middle East Respiratory Syndrome Coronavirus</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Infectious Disease Transmission, Patient-to-Professional</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Female</term><term>Health Personnel</term><term>Health Surveys</term><term>Humans</term><term>Incidence</term><term>Male</term><term>Middle Aged</term><term>Population Surveillance</term><term>Seroepidemiologic Studies</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Enquêtes de santé</term><term>Femelle</term><term>Humains</term><term>Incidence</term><term>Jeune adulte</term><term>Mâle</term><term>Personnel de santé</term><term>Sujet âgé</term><term>Surveillance de la population</term><term>Transmission de maladie infectieuse du patient au professionnel de santé</term><term>Études séroépidémiologiques</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Given the mode of transmission of Middle East respiratory syndrome (MERS), healthcare workers (HCWs) in contact with MERS patients are expected to be at risk of MERS infections. We evaluated the prevalence of MERS coronavirus (CoV) immunoglobulin (Ig) G in HCWs exposed to MERS patients and calculated the incidence of MERS-affected cases in HCWs. We enrolled HCWs from hospitals where confirmed MERS patients had visited. Serum was collected 4 to 6 weeks after the last contact with a confirmed MERS patient. We performed an enzyme-linked immunosorbent assay (ELISA) to screen for the presence of MERS-CoV IgG and an indirect immunofluorescence test (IIFT) to confirm MERS-CoV IgG. We used a questionnaire to collect information regarding the exposure. We calculated the incidence of MERS-affected cases by dividing the sum of PCR-confirmed and serology-confirmed cases by the number of exposed HCWs in participating hospitals. In total, 1169 HCWs in 31 hospitals had contact with 114 MERS patients, and among the HCWs, 15 were PCR-confirmed MERS cases in study hospitals. Serologic analysis was performed for 737 participants. ELISA was positive in five participants and borderline for seven. IIFT was positive for two (0.3%) of these 12 participants. Among the participants who did not use appropriate personal protective equipment (PPE), seropositivity was 0.7% (2/294) compared to 0% (0/443) in cases with appropriate PPE use. The incidence of MERS infection in HCWs was 1.5% (17/1169). The seroprevalence of MERS-CoV IgG among HCWs was higher among participants who did not use appropriate PPE.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Memish, Z A" uniqKey="Memish Z">Z.A. Memish</name></author><author><name sortKey="Zumla, A I" uniqKey="Zumla A">A.I. Zumla</name></author><author><name sortKey="Al Hakeem, R F" uniqKey="Al Hakeem R">R.F. Al-Hakeem</name></author><author><name sortKey="Al Rabeeah, A A" uniqKey="Al Rabeeah A">A.A. Al-Rabeeah</name></author><author><name sortKey="Stephens, G M" uniqKey="Stephens G">G.M. Stephens</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zaki, A M" uniqKey="Zaki A">A.M. Zaki</name></author><author><name sortKey="Van Boheemen, S" uniqKey="Van Boheemen S">S. van Boheemen</name></author><author><name sortKey="Bestebroer, T M" uniqKey="Bestebroer T">T.M. Bestebroer</name></author><author><name sortKey="Osterhaus, A D" uniqKey="Osterhaus A">A.D. Osterhaus</name></author><author><name sortKey="Fouchier, R A" uniqKey="Fouchier R">R.A. Fouchier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Oboho, I K" uniqKey="Oboho I">I.K. Oboho</name></author><author><name sortKey="Tomczyk, S M" uniqKey="Tomczyk S">S.M. Tomczyk</name></author><author><name sortKey="Al Asmari, A M" uniqKey="Al Asmari A">A.M. Al-Asmari</name></author><author><name sortKey="Banjar, A A" uniqKey="Banjar A">A.A. Banjar</name></author><author><name sortKey="Al Mugti, H" uniqKey="Al Mugti H">H. Al-Mugti</name></author><author><name sortKey="Aloraini, M S" uniqKey="Aloraini M">M.S. Aloraini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bermingham, A" uniqKey="Bermingham A">A. Bermingham</name></author><author><name sortKey="Chand, M A" uniqKey="Chand M">M.A. Chand</name></author><author><name sortKey="Brown, C S" uniqKey="Brown C">C.S. Brown</name></author><author><name sortKey="Aarons, E" uniqKey="Aarons E">E. Aarons</name></author><author><name sortKey="Tong, C" uniqKey="Tong C">C. Tong</name></author><author><name sortKey="Langrish, C" uniqKey="Langrish C">C. Langrish</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bialek, S R" uniqKey="Bialek S">S.R. Bialek</name></author><author><name sortKey="Allen, D" uniqKey="Allen D">D. Allen</name></author><author><name sortKey="Alvarado Ramy, F" uniqKey="Alvarado Ramy F">F. Alvarado-Ramy</name></author><author><name sortKey="Arthur, R" uniqKey="Arthur R">R. Arthur</name></author><author><name sortKey="Balajee, A" uniqKey="Balajee A">A. Balajee</name></author><author><name sortKey="Bell, D" uniqKey="Bell D">D. Bell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sridhar, S" uniqKey="Sridhar S">S. Sridhar</name></author><author><name sortKey="Brouqui, P" uniqKey="Brouqui P">P. Brouqui</name></author><author><name sortKey="Parola, P" uniqKey="Parola P">P. Parola</name></author><author><name sortKey="Gautret, P" uniqKey="Gautret P">P. Gautret</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Choi, J Y" uniqKey="Choi J">J.Y. Choi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Al Tawfiq, J A" uniqKey="Al Tawfiq J">J.A. Al-Tawfiq</name></author><author><name sortKey="Perl, T M" uniqKey="Perl T">T.M. Perl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Assiri, A" uniqKey="Assiri A">A. Assiri</name></author><author><name sortKey="Mcgeer, A" uniqKey="Mcgeer A">A. McGeer</name></author><author><name sortKey="Perl, T M" uniqKey="Perl T">T.M. Perl</name></author><author><name sortKey="Price, C S" uniqKey="Price C">C.S. Price</name></author><author><name sortKey="Al Rabeeah, A A" uniqKey="Al Rabeeah A">A.A. Al Rabeeah</name></author><author><name sortKey="Cummings, D A" uniqKey="Cummings D">D.A. Cummings</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Korea Centers For Disease Control And Prevention" uniqKey="Korea Centers For Disease Control And Prevention">Korea Centers for Disease Control and Prevention</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, J Y" uniqKey="Kim J">J.Y. Kim</name></author><author><name sortKey="Song, J Y" uniqKey="Song J">J.Y. Song</name></author><author><name sortKey="Yoon, Y K" uniqKey="Yoon Y">Y.K. Yoon</name></author><author><name sortKey="Choi, S H" uniqKey="Choi S">S.-H. Choi</name></author><author><name sortKey="Song, Y G" uniqKey="Song Y">Y.G. Song</name></author><author><name sortKey="Kim, S R" uniqKey="Kim S">S.-R. Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Breakwell, L" uniqKey="Breakwell L">L. Breakwell</name></author><author><name sortKey="Pringle, K" uniqKey="Pringle K">K. Pringle</name></author><author><name sortKey="Chea, N" uniqKey="Chea N">N. Chea</name></author><author><name sortKey="Allen, D" uniqKey="Allen D">D. Allen</name></author><author><name sortKey="Allen, S" uniqKey="Allen S">S. Allen</name></author><author><name sortKey="Richards, S" uniqKey="Richards S">S. Richards</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Korea Ministry Of Health And Welfare Korea Centers For Disease Control And Prevention" uniqKey="Korea Ministry Of Health And Welfare Korea Centers For Disease Control And Prevention">Korea Ministry of Health and Welfare; Korea Centers for Disease Control and Prevention</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Muller, M A" uniqKey="Muller M">M.A. Muller</name></author><author><name sortKey="Meyer, B" uniqKey="Meyer B">B. Meyer</name></author><author><name sortKey="Corman, V M" uniqKey="Corman V">V.M. Corman</name></author><author><name sortKey="Al Masri, M" uniqKey="Al Masri M">M. Al-Masri</name></author><author><name sortKey="Turkestani, A" uniqKey="Turkestani A">A. Turkestani</name></author><author><name sortKey="Ritz, D" uniqKey="Ritz D">D. Ritz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leung, G M" uniqKey="Leung G">G.M. Leung</name></author><author><name sortKey="Lim, W W" uniqKey="Lim W">W.W. Lim</name></author><author><name sortKey="Ho, L M" uniqKey="Ho L">L.M. Ho</name></author><author><name sortKey="Lam, T H" uniqKey="Lam T">T.H. Lam</name></author><author><name sortKey="Ghani, A C" uniqKey="Ghani A">A.C. Ghani</name></author><author><name sortKey="Donnelly, C A" uniqKey="Donnelly C">C.A. Donnelly</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Siegel, J D" uniqKey="Siegel J">J.D. Siegel</name></author><author><name sortKey="Rhinehart, E" uniqKey="Rhinehart E">E. Rhinehart</name></author><author><name sortKey="Jackson, M" uniqKey="Jackson M">M. Jackson</name></author><author><name sortKey="Chiarello, L" uniqKey="Chiarello L">L. Chiarello</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Al Abdallat, M M" uniqKey="Al Abdallat M">M.M. Al-Abdallat</name></author><author><name sortKey="Payne, D C" uniqKey="Payne D">D.C. Payne</name></author><author><name sortKey="Alqasrawi, S" uniqKey="Alqasrawi S">S. Alqasrawi</name></author><author><name sortKey="Rha, B" uniqKey="Rha B">B. Rha</name></author><author><name sortKey="Tohme, R A" uniqKey="Tohme R">R.A. Tohme</name></author><author><name sortKey="Abedi, G R" uniqKey="Abedi G">G.R. Abedi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Park, S" uniqKey="Park S">S. Park</name></author><author><name sortKey="Perera, R" uniqKey="Perera R">R. Perera</name></author><author><name sortKey="Choe, P" uniqKey="Choe P">P. Choe</name></author><author><name sortKey="Lau, E" uniqKey="Lau E">E. Lau</name></author><author><name sortKey="Choi, S" uniqKey="Choi S">S. Choi</name></author><author><name sortKey="Chun, J" uniqKey="Chun J">J. Chun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Park, W B" uniqKey="Park W">W.B. Park</name></author><author><name sortKey="Perera, R" uniqKey="Perera R">R. Perera</name></author><author><name sortKey="Choe, P G" uniqKey="Choe P">P.G. Choe</name></author><author><name sortKey="Lau, E" uniqKey="Lau E">E. Lau</name></author><author><name sortKey="Choi, S J" uniqKey="Choi S">S.J. Choi</name></author><author><name sortKey="Chun, J Y" uniqKey="Chun J">J.Y. Chun</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list></list><tree><noCountry><name sortKey="Bang, J H" sort="Bang, J H" uniqKey="Bang J" first="J. H." last="Bang">J. H. Bang</name><name sortKey="Choi, H J" sort="Choi, H J" uniqKey="Choi H" first="H. J." last="Choi">H. J. Choi</name><name sortKey="Choi, J K" sort="Choi, J K" uniqKey="Choi J" first="J. K." last="Choi">J. K. Choi</name><name sortKey="Choi, J P" sort="Choi, J P" uniqKey="Choi J" first="J.-P." last="Choi">J.-P. Choi</name><name sortKey="Choi, S M" sort="Choi, S M" uniqKey="Choi S" first="S.-M." last="Choi">S.-M. Choi</name><name sortKey="Choi, S Y" sort="Choi, S Y" uniqKey="Choi S" first="S.-Y." last="Choi">S.-Y. Choi</name><name sortKey="Choi, W S" sort="Choi, W S" uniqKey="Choi W" first="W. S." last="Choi">W. S. Choi</name><name sortKey="Choi, Y H" sort="Choi, Y H" uniqKey="Choi Y" first="Y. H." last="Choi">Y. H. Choi</name><name sortKey="Jang, H C" sort="Jang, H C" uniqKey="Jang H" first="H. C." last="Jang">H. C. Jang</name><name sortKey="Jeong, S J" sort="Jeong, S J" uniqKey="Jeong S" first="S. J." last="Jeong">S. J. Jeong</name><name sortKey="Jung, Y" sort="Jung, Y" uniqKey="Jung Y" first="Y." last="Jung">Y. Jung</name><name sortKey="Kiem, S" sort="Kiem, S" uniqKey="Kiem S" first="S." last="Kiem">S. Kiem</name><name sortKey="Kim, B N" sort="Kim, B N" uniqKey="Kim B" first="B.-N." last="Kim">B.-N. Kim</name><name sortKey="Kim, C J" sort="Kim, C J" uniqKey="Kim C" first="C.-J." last="Kim">C.-J. Kim</name><name sortKey="Kim, E S" sort="Kim, E S" uniqKey="Kim E" first="E. S." last="Kim">E. S. Kim</name><name sortKey="Kim, H Y" sort="Kim, H Y" uniqKey="Kim H" first="H. Y." last="Kim">H. Y. Kim</name><name sortKey="Kim, J" sort="Kim, J" uniqKey="Kim J" first="J." last="Kim">J. Kim</name><name sortKey="Kim, K H" sort="Kim, K H" uniqKey="Kim K" first="K.-H." last="Kim">K.-H. Kim</name><name sortKey="Kim, N J" sort="Kim, N J" uniqKey="Kim N" first="N.-J." last="Kim">N.-J. Kim</name><name sortKey="Kim, Y S" sort="Kim, Y S" uniqKey="Kim Y" first="Y.-S." last="Kim">Y.-S. Kim</name><name sortKey="Lee, H" sort="Lee, H" uniqKey="Lee H" first="H." last="Lee">H. Lee</name><name sortKey="Lee, J H" sort="Lee, J H" uniqKey="Lee J" first="J. H." last="Lee">J. H. Lee</name><name sortKey="Lee, K S" sort="Lee, K S" uniqKey="Lee K" first="K. S." last="Lee">K. S. Lee</name><name sortKey="Oh, W S" sort="Oh, W S" uniqKey="Oh W" first="W. S." last="Oh">W. S. Oh</name><name sortKey="Park, S" sort="Park, S" uniqKey="Park S" first="S." last="Park">S. Park</name><name sortKey="Park, S H" sort="Park, S H" uniqKey="Park S" first="S. H." last="Park">S. H. Park</name><name sortKey="Park, S Y" sort="Park, S Y" uniqKey="Park S" first="S. Y." last="Park">S. Y. Park</name><name sortKey="Rhee, J Y" sort="Rhee, J Y" uniqKey="Rhee J" first="J. Y." last="Rhee">J. Y. Rhee</name><name sortKey="Seol, H Y" sort="Seol, H Y" uniqKey="Seol H" first="H. Y." last="Seol">H. Y. Seol</name><name sortKey="Son, J S" sort="Son, J S" uniqKey="Son J" first="J. S." last="Son">J. S. Son</name><name sortKey="Wi, Y M" sort="Wi, Y M" uniqKey="Wi Y" first="Y.-M." last="Wi">Y.-M. Wi</name><name sortKey="Woo, H J" sort="Woo, H J" uniqKey="Woo H" first="H. J." last="Woo">H. J. Woo</name><name sortKey="Yoon, J H" sort="Yoon, J H" uniqKey="Yoon J" first="J. H." last="Yoon">J. H. Yoon</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Ncbi/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001729 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd -nk 001729 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= Ncbi
|étape= Checkpoint
|type= RBID
|clé= PMC:7128923
|texte= Surveillance of the Middle East respiratory syndrome (MERS) coronavirus (CoV) infection in healthcare workers after contact with confirmed MERS patients: incidence and risk factors of MERS-CoV seropositivity
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/RBID.i -Sk "pubmed:27475739" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a MersV1
| This area was generated with Dilib version V0.6.33. |  |