Oligonucleotide diversity and drug discovery
Identifieur interne : 004210 ( Main/Merge ); précédent : 004209; suivant : 004211Oligonucleotide diversity and drug discovery
Auteurs : Paul P. Trotta [États-Unis] ; Bruce A. Beutel [États-Unis] ; Michael I. Sherman [États-Unis]Source :
- Medicinal Research Reviews [ 0198-6325 ] ; 1995-07.
English descriptors
- Teeft :
- Acad, Active compounds, Acud, Affinity, Amplification, Antisense, Assay, Beutel, Bind, Binding affinity, Binding site, Chem, Chemical modification, Chemical modifications, Combinatorial, Combinatorial chemistry, Combinatorial chemistry approaches, Combinatorial libraries, Consensus sequence, Drug discovery, Extracellular, High affinity, High specificity, Intracellular, Intracellular targets, Large libraries, Large numbers, Loser, Many proteins, Modification, Molecule, Natl, Natural product extracts, Nucl, Nuclease, Nuclease digestion, Nucleic, Nucleic acids, Nucleic proteins, Nutl, Oligonucleotide, Oligonucleotide combinatorial chemistry, Oligonucleotide diversity, Oligonucleotide libraries, Oligonucleotide library, Oligonucleotide selection, Oligonucleotide selections, Oligonucleotide winners, Oligonucleotides, Oliphant, Other hand, Peptide, Proc, Protein targets, Ribozymes, Selection cycles, Selection procedure, Selection procedures, Small molecules, Structural proteins, Such proteins, Szostak, Target concentration, Target molecule, Target molecules, Target protein, Target proteins, Thrombin, Toxicity, Trotta, Winner, Winner oligonucleotides.
Url:
DOI: 10.1002/med.2610150403
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ISTEX:1476A7C5D62024376D4491BB11598D25ED27D7EALe document en format XML
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<term>Active compounds</term>
<term>Acud</term>
<term>Affinity</term>
<term>Amplification</term>
<term>Antisense</term>
<term>Assay</term>
<term>Beutel</term>
<term>Bind</term>
<term>Binding affinity</term>
<term>Binding site</term>
<term>Chem</term>
<term>Chemical modification</term>
<term>Chemical modifications</term>
<term>Combinatorial</term>
<term>Combinatorial chemistry</term>
<term>Combinatorial chemistry approaches</term>
<term>Combinatorial libraries</term>
<term>Consensus sequence</term>
<term>Drug discovery</term>
<term>Extracellular</term>
<term>High affinity</term>
<term>High specificity</term>
<term>Intracellular</term>
<term>Intracellular targets</term>
<term>Large libraries</term>
<term>Large numbers</term>
<term>Loser</term>
<term>Many proteins</term>
<term>Modification</term>
<term>Molecule</term>
<term>Natl</term>
<term>Natural product extracts</term>
<term>Nucl</term>
<term>Nuclease</term>
<term>Nuclease digestion</term>
<term>Nucleic</term>
<term>Nucleic acids</term>
<term>Nucleic proteins</term>
<term>Nutl</term>
<term>Oligonucleotide</term>
<term>Oligonucleotide combinatorial chemistry</term>
<term>Oligonucleotide diversity</term>
<term>Oligonucleotide libraries</term>
<term>Oligonucleotide library</term>
<term>Oligonucleotide selection</term>
<term>Oligonucleotide selections</term>
<term>Oligonucleotide winners</term>
<term>Oligonucleotides</term>
<term>Oliphant</term>
<term>Other hand</term>
<term>Peptide</term>
<term>Proc</term>
<term>Protein targets</term>
<term>Ribozymes</term>
<term>Selection cycles</term>
<term>Selection procedure</term>
<term>Selection procedures</term>
<term>Small molecules</term>
<term>Structural proteins</term>
<term>Such proteins</term>
<term>Szostak</term>
<term>Target concentration</term>
<term>Target molecule</term>
<term>Target molecules</term>
<term>Target protein</term>
<term>Target proteins</term>
<term>Thrombin</term>
<term>Toxicity</term>
<term>Trotta</term>
<term>Winner</term>
<term>Winner oligonucleotides</term>
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