Attenuation of skeletal muscle reperfusion injury with intravenous 12 amino acid peptides that bind to pathogenic IgM.
Identifieur interne : 002D78 ( Main/Merge ); précédent : 002D77; suivant : 002D79Attenuation of skeletal muscle reperfusion injury with intravenous 12 amino acid peptides that bind to pathogenic IgM.
Auteurs : Rodney K. Chan [États-Unis] ; Nicola Verna ; Jalil Afnan ; Ming Zhang ; Shahrul Ibrahim ; Michael C. Carroll ; Francis D. MooreSource :
- Surgery [ 0039-6060 ] ; 2006.
Descripteurs français
- KwdFr :
- Animaux, Banque de peptides, Immunoglobuline M (génétique), Immunoglobuline M (métabolisme), Lésion d'ischémie-reperfusion, Muscles squelettiques (anatomopathologie), Muscles squelettiques (immunologie), Peptides, Perfusions veineuses, Souris, Souris knockout, Électrophorèse sur gel de polyacrylamide.
- MESH :
- anatomopathologie : Muscles squelettiques.
- génétique : Immunoglobuline M.
- immunologie : Muscles squelettiques.
- métabolisme : Immunoglobuline M.
- Animaux, Banque de peptides, Lésion d'ischémie-reperfusion, Peptides, Perfusions veineuses, Souris, Souris knockout, Électrophorèse sur gel de polyacrylamide.
English descriptors
- KwdEn :
- MESH :
- chemical , genetics : Immunoglobulin M.
- chemical , metabolism : Immunoglobulin M.
- immunology : Muscle, Skeletal.
- pathology : Muscle, Skeletal.
- Animals, Electrophoresis, Polyacrylamide Gel, Infusions, Intravenous, Mice, Mice, Knockout, Peptide Library, Peptides, Reperfusion Injury.
Abstract
The injury sustained by reperfused skeletal muscle is inflammatory and is initiated by binding of pre-formed IgM to involved tissue, followed by local complement activation and further inflammation. A clone of natural IgM has been described that initiates this injury, suggesting that specific antigens are exposed on ischemic tissues that act as ligands for this pathogenic antibody. In these experiments, we examine the properties of short peptide sequences, and their homologues, that bind to the antigen-combining site of this pathogenic IgM clone.
DOI: 10.1016/j.surg.2005.05.028
PubMed: 16455333
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 002279
- to stream PubMed, to step Curation: 002279
- to stream PubMed, to step Checkpoint: 002154
- to stream Ncbi, to step Merge: 000404
- to stream Ncbi, to step Curation: 000404
- to stream Ncbi, to step Checkpoint: 000404
Links to Exploration step
pubmed:16455333Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Attenuation of skeletal muscle reperfusion injury with intravenous 12 amino acid peptides that bind to pathogenic IgM.</title><author><name sortKey="Chan, Rodney K" sort="Chan, Rodney K" uniqKey="Chan R" first="Rodney K" last="Chan">Rodney K. Chan</name><affiliation wicri:level="3"><nlm:affiliation>From the Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>From the Department of Surgery, Brigham and Women's Hospital, Harvard Medical School</wicri:orgArea></affiliation></author><author><name sortKey="Verna, Nicola" sort="Verna, Nicola" uniqKey="Verna N" first="Nicola" last="Verna">Nicola Verna</name></author><author><name sortKey="Afnan, Jalil" sort="Afnan, Jalil" uniqKey="Afnan J" first="Jalil" last="Afnan">Jalil Afnan</name></author><author><name sortKey="Zhang, Ming" sort="Zhang, Ming" uniqKey="Zhang M" first="Ming" last="Zhang">Ming Zhang</name></author><author><name sortKey="Ibrahim, Shahrul" sort="Ibrahim, Shahrul" uniqKey="Ibrahim S" first="Shahrul" last="Ibrahim">Shahrul Ibrahim</name></author><author><name sortKey="Carroll, Michael C" sort="Carroll, Michael C" uniqKey="Carroll M" first="Michael C" last="Carroll">Michael C. Carroll</name></author><author><name sortKey="Moore, Francis D" sort="Moore, Francis D" uniqKey="Moore F" first="Francis D" last="Moore">Francis D. Moore</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2006">2006</date><idno type="RBID">pubmed:16455333</idno><idno type="pmid">16455333</idno><idno type="doi">10.1016/j.surg.2005.05.028</idno><idno type="wicri:Area/PubMed/Corpus">002279</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002279</idno><idno type="wicri:Area/PubMed/Curation">002279</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002279</idno><idno type="wicri:Area/PubMed/Checkpoint">002154</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002154</idno><idno type="wicri:Area/Ncbi/Merge">000404</idno><idno type="wicri:Area/Ncbi/Curation">000404</idno><idno type="wicri:Area/Ncbi/Checkpoint">000404</idno><idno type="wicri:doubleKey">0039-6060:2006:Chan R:attenuation:of:skeletal</idno><idno type="wicri:Area/Main/Merge">002D78</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Attenuation of skeletal muscle reperfusion injury with intravenous 12 amino acid peptides that bind to pathogenic IgM.</title><author><name sortKey="Chan, Rodney K" sort="Chan, Rodney K" uniqKey="Chan R" first="Rodney K" last="Chan">Rodney K. Chan</name><affiliation wicri:level="3"><nlm:affiliation>From the Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston.</nlm:affiliation><country>États-Unis</country><placeName><settlement type="city">Boston</settlement><region type="state">Massachusetts</region></placeName><wicri:orgArea>From the Department of Surgery, Brigham and Women's Hospital, Harvard Medical School</wicri:orgArea></affiliation></author><author><name sortKey="Verna, Nicola" sort="Verna, Nicola" uniqKey="Verna N" first="Nicola" last="Verna">Nicola Verna</name></author><author><name sortKey="Afnan, Jalil" sort="Afnan, Jalil" uniqKey="Afnan J" first="Jalil" last="Afnan">Jalil Afnan</name></author><author><name sortKey="Zhang, Ming" sort="Zhang, Ming" uniqKey="Zhang M" first="Ming" last="Zhang">Ming Zhang</name></author><author><name sortKey="Ibrahim, Shahrul" sort="Ibrahim, Shahrul" uniqKey="Ibrahim S" first="Shahrul" last="Ibrahim">Shahrul Ibrahim</name></author><author><name sortKey="Carroll, Michael C" sort="Carroll, Michael C" uniqKey="Carroll M" first="Michael C" last="Carroll">Michael C. Carroll</name></author><author><name sortKey="Moore, Francis D" sort="Moore, Francis D" uniqKey="Moore F" first="Francis D" last="Moore">Francis D. Moore</name></author></analytic><series><title level="j">Surgery</title><idno type="ISSN">0039-6060</idno><imprint><date when="2006" type="published">2006</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Electrophoresis, Polyacrylamide Gel</term><term>Immunoglobulin M (genetics)</term><term>Immunoglobulin M (metabolism)</term><term>Infusions, Intravenous</term><term>Mice</term><term>Mice, Knockout</term><term>Muscle, Skeletal (immunology)</term><term>Muscle, Skeletal (pathology)</term><term>Peptide Library</term><term>Peptides</term><term>Reperfusion Injury</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Banque de peptides</term><term>Immunoglobuline M (génétique)</term><term>Immunoglobuline M (métabolisme)</term><term>Lésion d'ischémie-reperfusion</term><term>Muscles squelettiques (anatomopathologie)</term><term>Muscles squelettiques (immunologie)</term><term>Peptides</term><term>Perfusions veineuses</term><term>Souris</term><term>Souris knockout</term><term>Électrophorèse sur gel de polyacrylamide</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Immunoglobulin M</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Immunoglobulin M</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Muscles squelettiques</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Immunoglobuline M</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Muscles squelettiques</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Muscle, Skeletal</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Immunoglobuline M</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Muscle, Skeletal</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Electrophoresis, Polyacrylamide Gel</term><term>Infusions, Intravenous</term><term>Mice</term><term>Mice, Knockout</term><term>Peptide Library</term><term>Peptides</term><term>Reperfusion Injury</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Banque de peptides</term><term>Lésion d'ischémie-reperfusion</term><term>Peptides</term><term>Perfusions veineuses</term><term>Souris</term><term>Souris knockout</term><term>Électrophorèse sur gel de polyacrylamide</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The injury sustained by reperfused skeletal muscle is inflammatory and is initiated by binding of pre-formed IgM to involved tissue, followed by local complement activation and further inflammation. A clone of natural IgM has been described that initiates this injury, suggesting that specific antigens are exposed on ischemic tissues that act as ligands for this pathogenic antibody. In these experiments, we examine the properties of short peptide sequences, and their homologues, that bind to the antigen-combining site of this pathogenic IgM clone.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002D78 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 002D78 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= Main
|étape= Merge
|type= RBID
|clé= pubmed:16455333
|texte= Attenuation of skeletal muscle reperfusion injury with intravenous 12 amino acid peptides that bind to pathogenic IgM.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Merge/RBID.i -Sk "pubmed:16455333" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Merge/biblio.hfd \
| NlmPubMed2Wicri -a MersV1
| This area was generated with Dilib version V0.6.33. |  |