Serveur d'exploration MERS

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Stillbirth During Infection With Middle East Respiratory Syndrome Coronavirus

Identifieur interne : 001A85 ( Main/Merge ); précédent : 001A84; suivant : 001A86

Stillbirth During Infection With Middle East Respiratory Syndrome Coronavirus

Auteurs : Daniel C. Payne ; Ibrahim Iblan ; Sultan Alqasrawi ; Mohannad Al Nsour [Jordanie] ; Brian Rha ; Rania A. Tohme ; Glen R. Abedi ; Noha H. Farag ; Aktham Haddadin ; Tarek Al Sanhouri ; Najwa Jarour ; David L. Swerdlow ; Denise J. Jamieson [Géorgie (pays)] ; Mark A. Pallansch ; Lia M. Haynes ; Susan I. Gerber ; Mohammad Mousa Al Abdallat

Source :

RBID : PMC:4618552

Descripteurs français

English descriptors

Abstract

Abstract

We conducted an epidemiologic investigation among survivors of an outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in Jordan. A second-trimester stillbirth occurred during the course of an acute respiratory illness that was attributed to MERS-CoV on the basis of exposure history and positive results of MERS-CoV serologic testing. This is the first occurrence of stillbirth during an infection with MERS-CoV and may have bearing upon the surveillance and management of pregnant women in settings of unexplained respiratory illness potentially due to MERS-CoV. Future prospective investigations of MERS-CoV should ascertain pregnancy status and obtain further pregnancy-related data, including biological specimens for confirmatory testing.


Url:
DOI: 10.1093/infdis/jiu068
PubMed: 24474813
PubMed Central: 4618552

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PMC:4618552

Le document en format XML

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<name sortKey="Farag, Noha H" sort="Farag, Noha H" uniqKey="Farag N" first="Noha H." last="Farag">Noha H. Farag</name>
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<name sortKey="Haddadin, Aktham" sort="Haddadin, Aktham" uniqKey="Haddadin A" first="Aktham" last="Haddadin">Aktham Haddadin</name>
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<name sortKey="Al Sanhouri, Tarek" sort="Al Sanhouri, Tarek" uniqKey="Al Sanhouri T" first="Tarek" last="Al Sanhouri">Tarek Al Sanhouri</name>
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<nlm:aff id="af7">
<institution>Communicable Diseases Directorate</institution>
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<name sortKey="Swerdlow, David L" sort="Swerdlow, David L" uniqKey="Swerdlow D" first="David L." last="Swerdlow">David L. Swerdlow</name>
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<addr-line>Division of Viral Diseases</addr-line>
,
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<name sortKey="Jamieson, Denise J" sort="Jamieson, Denise J" uniqKey="Jamieson D" first="Denise J." last="Jamieson">Denise J. Jamieson</name>
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,
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<author>
<name sortKey="Haynes, Lia M" sort="Haynes, Lia M" uniqKey="Haynes L" first="Lia M." last="Haynes">Lia M. Haynes</name>
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<addr-line>Division of Viral Diseases</addr-line>
,
<institution>National Center for Immunization and Respiratory Diseases</institution>
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<name sortKey="Gerber, Susan I" sort="Gerber, Susan I" uniqKey="Gerber S" first="Susan I." last="Gerber">Susan I. Gerber</name>
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<addr-line>Division of Viral Diseases</addr-line>
,
<institution>National Center for Immunization and Respiratory Diseases</institution>
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<name sortKey="Al Abdallat, Mohammad Mousa" sort="Al Abdallat, Mohammad Mousa" uniqKey="Al Abdallat M" first="Mohammad Mousa" last="Al Abdallat">Mohammad Mousa Al Abdallat</name>
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,
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<name sortKey="Alqasrawi, Sultan" sort="Alqasrawi, Sultan" uniqKey="Alqasrawi S" first="Sultan" last="Alqasrawi">Sultan Alqasrawi</name>
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<institution>Eastern Mediterranean Public Health Network</institution>
,
<addr-line>Amman</addr-line>
,
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<country xml:lang="fr">Jordanie</country>
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<name sortKey="Rha, Brian" sort="Rha, Brian" uniqKey="Rha B" first="Brian" last="Rha">Brian Rha</name>
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<nlm:aff id="af1">
<addr-line>Division of Viral Diseases</addr-line>
,
<institution>National Center for Immunization and Respiratory Diseases</institution>
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<affiliation>
<nlm:aff id="af2">
<addr-line>Epidemic Intelligence Service</addr-line>
</nlm:aff>
</affiliation>
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<name sortKey="Tohme, Rania A" sort="Tohme, Rania A" uniqKey="Tohme R" first="Rania A." last="Tohme">Rania A. Tohme</name>
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<nlm:aff id="af3">
<addr-line>Global Immunization Division, Center for Global Health</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">Center for Global Health</wicri:noCountry>
</affiliation>
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<name sortKey="Abedi, Glen R" sort="Abedi, Glen R" uniqKey="Abedi G" first="Glen R." last="Abedi">Glen R. Abedi</name>
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<nlm:aff id="af1">
<addr-line>Division of Viral Diseases</addr-line>
,
<institution>National Center for Immunization and Respiratory Diseases</institution>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Farag, Noha H" sort="Farag, Noha H" uniqKey="Farag N" first="Noha H." last="Farag">Noha H. Farag</name>
<affiliation>
<nlm:aff id="af4">
<addr-line>Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases</addr-line>
</nlm:aff>
<wicri:noCountry code="subfield">National Center for Emerging and Zoonotic Infectious Diseases</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Haddadin, Aktham" sort="Haddadin, Aktham" uniqKey="Haddadin A" first="Aktham" last="Haddadin">Aktham Haddadin</name>
<affiliation>
<nlm:aff id="af8">
<addr-line>Directorate of Laboratories</addr-line>
,
<institution>Jordan Ministry of Health</institution>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Al Sanhouri, Tarek" sort="Al Sanhouri, Tarek" uniqKey="Al Sanhouri T" first="Tarek" last="Al Sanhouri">Tarek Al Sanhouri</name>
<affiliation>
<nlm:aff id="af8">
<addr-line>Directorate of Laboratories</addr-line>
,
<institution>Jordan Ministry of Health</institution>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Jarour, Najwa" sort="Jarour, Najwa" uniqKey="Jarour N" first="Najwa" last="Jarour">Najwa Jarour</name>
<affiliation>
<nlm:aff id="af7">
<institution>Communicable Diseases Directorate</institution>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Swerdlow, David L" sort="Swerdlow, David L" uniqKey="Swerdlow D" first="David L." last="Swerdlow">David L. Swerdlow</name>
<affiliation>
<nlm:aff id="af1">
<addr-line>Division of Viral Diseases</addr-line>
,
<institution>National Center for Immunization and Respiratory Diseases</institution>
</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Jamieson, Denise J" sort="Jamieson, Denise J" uniqKey="Jamieson D" first="Denise J." last="Jamieson">Denise J. Jamieson</name>
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<nlm:aff id="af5">
<addr-line>Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion</addr-line>
,
<institution>Centers for Disease Control and Prevention</institution>
,
<addr-line>Atlanta, Georgia</addr-line>
</nlm:aff>
<country xml:lang="fr">Géorgie (pays)</country>
<wicri:regionArea>Atlanta</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Pallansch, Mark A" sort="Pallansch, Mark A" uniqKey="Pallansch M" first="Mark A." last="Pallansch">Mark A. Pallansch</name>
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<nlm:aff id="af1">
<addr-line>Division of Viral Diseases</addr-line>
,
<institution>National Center for Immunization and Respiratory Diseases</institution>
</nlm:aff>
</affiliation>
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<name sortKey="Haynes, Lia M" sort="Haynes, Lia M" uniqKey="Haynes L" first="Lia M." last="Haynes">Lia M. Haynes</name>
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<nlm:aff id="af1">
<addr-line>Division of Viral Diseases</addr-line>
,
<institution>National Center for Immunization and Respiratory Diseases</institution>
</nlm:aff>
</affiliation>
</author>
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<name sortKey="Gerber, Susan I" sort="Gerber, Susan I" uniqKey="Gerber S" first="Susan I." last="Gerber">Susan I. Gerber</name>
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<nlm:aff id="af1">
<addr-line>Division of Viral Diseases</addr-line>
,
<institution>National Center for Immunization and Respiratory Diseases</institution>
</nlm:aff>
</affiliation>
</author>
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<name sortKey="Al Abdallat, Mohammad Mousa" sort="Al Abdallat, Mohammad Mousa" uniqKey="Al Abdallat M" first="Mohammad Mousa" last="Al Abdallat">Mohammad Mousa Al Abdallat</name>
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<nlm:aff id="af7">
<institution>Communicable Diseases Directorate</institution>
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<title level="j">The Journal of Infectious Diseases</title>
<idno type="ISSN">0022-1899</idno>
<idno type="eISSN">1537-6613</idno>
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<term>Adolescent</term>
<term>Adult</term>
<term>Coronavirus (isolation & purification)</term>
<term>Coronavirus Infections (diagnosis)</term>
<term>Coronavirus Infections (epidemiology)</term>
<term>Female</term>
<term>Humans</term>
<term>Jordan</term>
<term>Pregnancy</term>
<term>Respiratory Tract Infections (diagnosis)</term>
<term>Respiratory Tract Infections (epidemiology)</term>
<term>Respiratory Tract Infections (virology)</term>
<term>Retrospective Studies</term>
<term>Stillbirth (epidemiology)</term>
<term>Young Adult</term>
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<term>Adolescent</term>
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<term>Grossesse</term>
<term>Humains</term>
<term>Infections de l'appareil respiratoire (diagnostic)</term>
<term>Infections de l'appareil respiratoire (virologie)</term>
<term>Infections de l'appareil respiratoire (épidémiologie)</term>
<term>Infections à coronavirus (diagnostic)</term>
<term>Infections à coronavirus (épidémiologie)</term>
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<term>Coronavirus Infections</term>
<term>Respiratory Tract Infections</term>
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<term>Infections de l'appareil respiratoire</term>
<term>Infections à coronavirus</term>
</keywords>
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<term>Coronavirus Infections</term>
<term>Respiratory Tract Infections</term>
<term>Stillbirth</term>
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<term>Coronavirus</term>
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<term>Infections de l'appareil respiratoire</term>
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<term>Respiratory Tract Infections</term>
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<term>Infections à coronavirus</term>
<term>Mortinaissance</term>
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<term>Adolescent</term>
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<term>Jeune adulte</term>
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<front>
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<title>Abstract</title>
<p>We conducted an epidemiologic investigation among survivors of an outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in Jordan. A second-trimester stillbirth occurred during the course of an acute respiratory illness that was attributed to MERS-CoV on the basis of exposure history and positive results of MERS-CoV serologic testing. This is the first occurrence of stillbirth during an infection with MERS-CoV and may have bearing upon the surveillance and management of pregnant women in settings of unexplained respiratory illness potentially due to MERS-CoV. Future prospective investigations of MERS-CoV should ascertain pregnancy status and obtain further pregnancy-related data, including biological specimens for confirmatory testing.</p>
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