Middle East respiratory syndrome coronavirus intermittent positive cases: Implications for infection control
Identifieur interne : 000895 ( Main/Merge ); précédent : 000894; suivant : 000896Middle East respiratory syndrome coronavirus intermittent positive cases: Implications for infection control
Auteurs : Sarah H. Alfaraj [Arabie saoudite, Canada] ; Jaffar A. Al-Tawfiq [Arabie saoudite, États-Unis] ; Ziad A. Memish [Arabie saoudite, États-Unis]Source :
- American Journal of Infection Control [ 0196-6553 ] ; 2018.
Descripteurs français
- KwdFr :
- Arabie saoudite (épidémiologie), Coronavirus du syndrome respiratoire du Moyen-Orient (isolement et purification), Humains, Hôpitaux, Infections à coronavirus (diagnostic), Infections à coronavirus (épidémiologie), Lutte contre l'infection (), Partie nasale du pharynx (virologie), RT-PCR (), Tests diagnostiques courants (), Études rétrospectives.
- MESH :
- diagnostic : Infections à coronavirus.
- isolement et purification : Coronavirus du syndrome respiratoire du Moyen-Orient.
- virologie : Partie nasale du pharynx.
- épidémiologie : Arabie saoudite, Infections à coronavirus.
- Humains, Hôpitaux, Lutte contre l'infection, RT-PCR, Tests diagnostiques courants, Études rétrospectives.
- Wicri :
- geographic : Arabie saoudite.
English descriptors
- KwdEn :
- Coronavirus Infections (diagnosis), Coronavirus Infections (epidemiology), Diagnostic Tests, Routine (methods), Hospitals, Humans, Infection Control (methods), Middle East Respiratory Syndrome Coronavirus (isolation & purification), Nasopharynx (virology), Retrospective Studies, Reverse Transcriptase Polymerase Chain Reaction (methods), Saudi Arabia (epidemiology).
- MESH :
- geographic , epidemiology : Saudi Arabia.
- diagnosis : Coronavirus Infections.
- epidemiology : Coronavirus Infections.
- isolation & purification : Middle East Respiratory Syndrome Coronavirus.
- methods : Diagnostic Tests, Routine, Infection Control, Reverse Transcriptase Polymerase Chain Reaction.
- virology : Nasopharynx.
- Hospitals, Humans, Retrospective Studies.
Abstract
Middle East respiratory syndrome coronavirus (MERS-CoV) continues to be reported from the Kingdom of Saudi Arabia. Data on the phenomenon of intermittent positive results for MERS-CoV on reverse-transcription polymerase chain reaction (RT-PCR) with negative results in between are lacking. Here we describe cases with intermittent positive MERS-CoV test results and highlight the required number of tests to rule out or rule in MERS-CoV infection based on a large retrospective cohort of patients with confirmed MERS-CoV.
This analysis included cases admitted between January 2014 and December 2017. The included patients had a minimum of 3 nasopharyngeal MERS-CoV RT-PCR tests for confirmation and needed 2 negative samples for MERS-CoV evaluated 48 hours apart with clinical improvement or stabilization apart to ensure clearance.
A total of 408 patients with positive MERS-CoV test results were treated at the referring hospital. We excluded 72 patients who had only 1 swab result available in the system and were treated in the initial years of the disease. Of the remaining 336 patients, 300 (89%) had a positive result after 1 swab, 324 (96.5%) had a positive result after 2 consecutive swabs, and 328 (97.6%) had a positive result after 3 consecutive swabs. Of the total cases, 46 (13.7%) had a positive MERS-CoV test then a negative test, followed by positive test results.
Our data indicate that 2 to 3 nasopharyngeal samples are needed to produce the highest yield of positive results for MERS-CoV. In addition, 2 negative results 48 hours apart with clinical improvement or stabilization are needed to clear patients from MERS-CoV. Evaluation of the yield of sputum samples is needed to assess the effectiveness against nasopharyngeal swabs.
Url:
DOI: 10.1016/j.ajic.2018.08.020
PubMed: 30352694
PubMed Central: 7115256
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PMC:7115256Le document en format XML
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<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p>Middle East respiratory syndrome coronavirus (MERS-CoV) continues to be reported from the Kingdom of Saudi Arabia. Data on the phenomenon of intermittent positive results for MERS-CoV on reverse-transcription polymerase chain reaction (RT-PCR) with negative results in between are lacking. Here we describe cases with intermittent positive MERS-CoV test results and highlight the required number of tests to rule out or rule in MERS-CoV infection based on a large retrospective cohort of patients with confirmed MERS-CoV.</p>
</sec>
<sec><title>Methods</title>
<p>This analysis included cases admitted between January 2014 and December 2017. The included patients had a minimum of 3 nasopharyngeal MERS-CoV RT-PCR tests for confirmation and needed 2 negative samples for MERS-CoV evaluated 48 hours apart with clinical improvement or stabilization apart to ensure clearance.</p>
</sec>
<sec><title>Results</title>
<p>A total of 408 patients with positive MERS-CoV test results were treated at the referring hospital. We excluded 72 patients who had only 1 swab result available in the system and were treated in the initial years of the disease. Of the remaining 336 patients, 300 (89%) had a positive result after 1 swab, 324 (96.5%) had a positive result after 2 consecutive swabs, and 328 (97.6%) had a positive result after 3 consecutive swabs. Of the total cases, 46 (13.7%) had a positive MERS-CoV test then a negative test, followed by positive test results.</p>
</sec>
<sec><title>Conclusions</title>
<p>Our data indicate that 2 to 3 nasopharyngeal samples are needed to produce the highest yield of positive results for MERS-CoV. In addition, 2 negative results 48 hours apart with clinical improvement or stabilization are needed to clear patients from MERS-CoV. Evaluation of the yield of sputum samples is needed to assess the effectiveness against nasopharyngeal swabs.</p>
</sec>
</div>
</front>
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</author>
<author><name sortKey="Auwaerter, Pg" uniqKey="Auwaerter P">PG Auwaerter</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lim, Pl" uniqKey="Lim P">PL. Lim</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kim, Kh" uniqKey="Kim K">KH Kim</name>
</author>
<author><name sortKey="Tandi, Te" uniqKey="Tandi T">TE Tandi</name>
</author>
<author><name sortKey="Choi, Jw" uniqKey="Choi J">JW Choi</name>
</author>
<author><name sortKey="Moon, Jm" uniqKey="Moon J">JM Moon</name>
</author>
<author><name sortKey="Kim, Ms" uniqKey="Kim M">MS Kim</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Park, Ys" uniqKey="Park Y">YS Park</name>
</author>
<author><name sortKey="Lee, C" uniqKey="Lee C">C Lee</name>
</author>
<author><name sortKey="Kim, Km" uniqKey="Kim K">KM Kim</name>
</author>
<author><name sortKey="Kim, Sw" uniqKey="Kim S">SW Kim</name>
</author>
<author><name sortKey="Lee, Kj" uniqKey="Lee K">KJ Lee</name>
</author>
<author><name sortKey="Ahn, J" uniqKey="Ahn J">J Ahn</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Memish, Za" uniqKey="Memish Z">ZA Memish</name>
</author>
<author><name sortKey="Assiri, Am" uniqKey="Assiri A">AM Assiri</name>
</author>
<author><name sortKey="Al Tawfiq, Ja" uniqKey="Al Tawfiq J">JA Al-Tawfiq</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Al Tawfiq, Ja" uniqKey="Al Tawfiq J">JA Al-Tawfiq</name>
</author>
<author><name sortKey="Hinedi, K" uniqKey="Hinedi K">K Hinedi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Huh, Hj" uniqKey="Huh H">HJ Huh</name>
</author>
<author><name sortKey="Ko, Jh" uniqKey="Ko J">JH Ko</name>
</author>
<author><name sortKey="Kim, Ye" uniqKey="Kim Y">YE Kim</name>
</author>
<author><name sortKey="Park, Ch" uniqKey="Park C">CH Park</name>
</author>
<author><name sortKey="Hong, G" uniqKey="Hong G">G Hong</name>
</author>
<author><name sortKey="Choi, R" uniqKey="Choi R">R Choi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Oh, M" uniqKey="Oh M">M Oh</name>
</author>
<author><name sortKey="Park, Wb" uniqKey="Park W">WB Park</name>
</author>
<author><name sortKey="Choe, Pg" uniqKey="Choe P">PG Choe</name>
</author>
<author><name sortKey="Choi, Sj" uniqKey="Choi S">SJ Choi</name>
</author>
<author><name sortKey="Kim, Ji" uniqKey="Kim J">JI Kim</name>
</author>
<author><name sortKey="Chae, J" uniqKey="Chae J">J Chae</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Park, Wb" uniqKey="Park W">WB Park</name>
</author>
<author><name sortKey="Poon, Llm" uniqKey="Poon L">LLM Poon</name>
</author>
<author><name sortKey="Choi, Sj" uniqKey="Choi S">SJ Choi</name>
</author>
<author><name sortKey="Choe, Pg" uniqKey="Choe P">PG Choe</name>
</author>
<author><name sortKey="Song, Kh" uniqKey="Song K">KH Song</name>
</author>
<author><name sortKey="Bang, Jh" uniqKey="Bang J">JH Bang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Drosten, C" uniqKey="Drosten C">C Drosten</name>
</author>
<author><name sortKey="Seilmaier, M" uniqKey="Seilmaier M">M Seilmaier</name>
</author>
<author><name sortKey="Corman, Vm" uniqKey="Corman V">VM Corman</name>
</author>
<author><name sortKey="Hartmann, W" uniqKey="Hartmann W">W Hartmann</name>
</author>
<author><name sortKey="Scheible, G" uniqKey="Scheible G">G Scheible</name>
</author>
<author><name sortKey="Sack, S" uniqKey="Sack S">S Sack</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Guery, B" uniqKey="Guery B">B Guery</name>
</author>
<author><name sortKey="Poissy, J" uniqKey="Poissy J">J Poissy</name>
</author>
<author><name sortKey="El Mansouf, L" uniqKey="El Mansouf L">L el Mansouf</name>
</author>
<author><name sortKey="Sejourne, C" uniqKey="Sejourne C">C Séjourné</name>
</author>
<author><name sortKey="Ettahar, N" uniqKey="Ettahar N">N Ettahar</name>
</author>
<author><name sortKey="Lemaire, X" uniqKey="Lemaire X">X Lemaire</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kapoor, M" uniqKey="Kapoor M">M Kapoor</name>
</author>
<author><name sortKey="Pringle, K" uniqKey="Pringle K">K Pringle</name>
</author>
<author><name sortKey="Kumar, A" uniqKey="Kumar A">A Kumar</name>
</author>
<author><name sortKey="Dearth, S" uniqKey="Dearth S">S Dearth</name>
</author>
<author><name sortKey="Liu, L" uniqKey="Liu L">L Liu</name>
</author>
<author><name sortKey="Lovchik, J" uniqKey="Lovchik J">J Lovchik</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Amer, H" uniqKey="Amer H">H Amer</name>
</author>
<author><name sortKey="Alqahtani, As" uniqKey="Alqahtani A">AS Alqahtani</name>
</author>
<author><name sortKey="Alaklobi, F" uniqKey="Alaklobi F">F Alaklobi</name>
</author>
<author><name sortKey="Altayeb, J" uniqKey="Altayeb J">J Altayeb</name>
</author>
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</author>
<author><name sortKey="Alzoman, H" uniqKey="Alzoman H">H Alzoman</name>
</author>
<author><name sortKey="Aljerian, N" uniqKey="Aljerian N">N Aljerian</name>
</author>
<author><name sortKey="Memish, Za" uniqKey="Memish Z">ZA Memish</name>
</author>
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</author>
<author><name sortKey="Alkhamis, Am" uniqKey="Alkhamis A">AM Alkhamis</name>
</author>
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</author>
<author><name sortKey="Tamin, A" uniqKey="Tamin A">A Tamin</name>
</author>
<author><name sortKey="Binder, Am" uniqKey="Binder A">AM Binder</name>
</author>
</analytic>
</biblStruct>
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</author>
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</author>
<author><name sortKey="Cao, Z" uniqKey="Cao Z">Z Cao</name>
</author>
<author><name sortKey="Jin, H" uniqKey="Jin H">H Jin</name>
</author>
<author><name sortKey="Chi, H" uniqKey="Chi H">H Chi</name>
</author>
<author><name sortKey="Zhao, J" uniqKey="Zhao J">J Zhao</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
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</author>
<author><name sortKey="Chan, Kh" uniqKey="Chan K">KH Chan</name>
</author>
<author><name sortKey="Hong, C" uniqKey="Hong C">C Hong</name>
</author>
<author><name sortKey="Kang, Y" uniqKey="Kang Y">Y Kang</name>
</author>
<author><name sortKey="Ge, S" uniqKey="Ge S">S Ge</name>
</author>
<author><name sortKey="Chen, H" uniqKey="Chen H">H Chen</name>
</author>
</analytic>
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