Real-time machine learning classification of pallidal borders during deep brain stimulation surgery.
Identifieur interne : 000099 ( Main/Exploration ); précédent : 000098; suivant : 000100Real-time machine learning classification of pallidal borders during deep brain stimulation surgery.
Auteurs : Dan Valsky [Israël] ; Kim T. Blackwell ; Idit Tamir ; Renana Eitan ; Hagai Bergman ; Zvi IsraelSource :
- Journal of neural engineering [ 1741-2552 ] ; 2020.
Abstract
Deep brain stimulation (DBS) of the internal segment of the globus pallidus (GPi) in patients with Parkinson's disease and dystonia improves motor symptoms and quality of life. Traditionally, pallidal borders have been demarcated by electrophysiological microelectrode recordings (MERs) during DBS surgery. However, detection of pallidal borders can be challenging due to the variability of the firing characteristics of neurons encountered along the trajectory. MER can also be time-consuming and therefore costly. Here we show the feasibility of real-time machine learning classification of striato-pallidal borders to assist neurosurgeons during DBS surgery.
DOI: 10.1088/1741-2552/ab53ac
PubMed: 31675740
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Deep brain stimulation (DBS) of the internal segment of the globus pallidus (GPi) in patients with Parkinson's disease and dystonia improves motor symptoms and quality of life. Traditionally, pallidal borders have been demarcated by electrophysiological microelectrode recordings (MERs) during DBS surgery. However, detection of pallidal borders can be challenging due to the variability of the firing characteristics of neurons encountered along the trajectory. MER can also be time-consuming and therefore costly. Here we show the feasibility of real-time machine learning classification of striato-pallidal borders to assist neurosurgeons during DBS surgery.</div>
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