Comparison between soluble components of adenovirus types 3 and 16 and of the intermediate strain 3–16 (the San Carlos Agent)
Identifieur interne : 005228 ( Main/Exploration ); précédent : 005227; suivant : 005229Comparison between soluble components of adenovirus types 3 and 16 and of the intermediate strain 3–16 (the San Carlos Agent)
Auteurs : Erling Norrby [Suède] ; Per Skaaret [Suède]Source :
- Virology [ 0042-6822 ] ; 1968.
English descriptors
- Teeft :
- Adenovirtts type, Adenovirus, Adenovirus type, Adenovirus types, Albumin peak, Antiadenovirus type, Biological activities, Capsomers, Centrifugation, Corresponding components, Different components, Different symbols, Different types, Dimer, Elution diagram, Erythrocyte, Erythrocyte absorptions, Exclusion chromatography, First absorption, Hexons, Intermediate strain, Latter samples, Norrby, Pentons, Physiological saline, Representative experiment, Sedimenting, Serotypes, Skaaret, Small quantities, Soluble, Soluble adenovirus, Soluble components, Sorrby, Speed centrifugation, Subgroup, Toxin, Toxin activity, Trypsin, Trypsin treatment, Vertex capsomers, Virion, Water bath, Zonal, Zonal centrifugation.
Abstract
Abstract: The San Carlos agent, an adenovirus (type 3–16) sharing characteristics of type 3 by neutralization and of type 16 by hemagglutination inhibition (HI) tests, has been compared with types 3 and 16 with regard to physical-chemical properties of different structural components. No marked differences were found between the properties of isolated hexons, pentons (i.e., the incomplete hemagglutinin, HA, demonstrable in the presence of heterotypic immune sera), and fibers (i.e., the slowly sedimenting HI antibody-consuming components) of the three materials. However, the soluble complete HA's exhibited markedly different characteristics. The results indicate that they are carried by the following subunit aggregates: type 3—dodecahedral aggregates of pentons plus some extra structure; type 3–16—smaller polymers (probably dimers) of pentons; type 16—small polymers (probably dimers) of pentons or of fibers. Some members of Rosen's subgroup III (types 1, 2, 5, 6) show soluble complete HA subunit activities qualitatively similar to those of type 16.Soluble complete HA's containing small polymers of pentons were distinguished from those containing only fibers by the following properties; (a) a more rapid rate of sedimentation, (b) presence of toxin (cell-detachment) activity, (c) sensitivity to trypsin treatment, (d) presence of vertex capsomer antigen demonstrable by its hemagglutination enhancement antibody-consuming activity, and (e) a marked enhancement of the HA activity in the presence of heterotypic antisera.
Url:
DOI: 10.1016/0042-6822(68)90137-2
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001760
- to stream Istex, to step Curation: 001760
- to stream Istex, to step Checkpoint: 002667
- to stream Main, to step Merge: 005308
- to stream Main, to step Curation: 005228
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Comparison between soluble components of adenovirus types 3 and 16 and of the intermediate strain 3–16 (the San Carlos Agent)</title><author><name sortKey="Norrby, Erling" sort="Norrby, Erling" uniqKey="Norrby E" first="Erling" last="Norrby">Erling Norrby</name></author><author><name sortKey="Skaaret, Per" sort="Skaaret, Per" uniqKey="Skaaret P" first="Per" last="Skaaret">Per Skaaret</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:9C983233081CACF35D621CA2BAA14FC6289CF262</idno><date when="1968" year="1968">1968</date><idno type="doi">10.1016/0042-6822(68)90137-2</idno><idno type="url">https://api.istex.fr/ark:/67375/6H6-Z8NJSNG4-0/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">001760</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001760</idno><idno type="wicri:Area/Istex/Curation">001760</idno><idno type="wicri:Area/Istex/Checkpoint">002667</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">002667</idno><idno type="wicri:doubleKey">0042-6822:1968:Norrby E:comparison:between:soluble</idno><idno type="wicri:Area/Main/Merge">005308</idno><idno type="wicri:Area/Main/Curation">005228</idno><idno type="wicri:Area/Main/Exploration">005228</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a">Comparison between soluble components of adenovirus types 3 and 16 and of the intermediate strain 3–16 (the San Carlos Agent)</title><author><name sortKey="Norrby, Erling" sort="Norrby, Erling" uniqKey="Norrby E" first="Erling" last="Norrby">Erling Norrby</name><affiliation wicri:level="4"><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Virology, Karolinska Institutel, Faculty of Medicine, Stockholm University</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="1">Svealand</region><region nuts="1">Comté de Stockholm</region></placeName><orgName type="university">Université de Stockholm</orgName></affiliation></author><author><name sortKey="Skaaret, Per" sort="Skaaret, Per" uniqKey="Skaaret P" first="Per" last="Skaaret">Per Skaaret</name><affiliation wicri:level="4"><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Virology, Karolinska Institutel, Faculty of Medicine, Stockholm University</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="1">Svealand</region><region nuts="1">Comté de Stockholm</region></placeName><orgName type="university">Université de Stockholm</orgName></affiliation></author></analytic><monogr></monogr><series><title level="j">Virology</title><title level="j" type="abbrev">YVIRO</title><idno type="ISSN">0042-6822</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1968">1968</date><biblScope unit="volume">36</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="201">201</biblScope><biblScope unit="page" to="211">211</biblScope></imprint><idno type="ISSN">0042-6822</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0042-6822</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Adenovirtts type</term><term>Adenovirus</term><term>Adenovirus type</term><term>Adenovirus types</term><term>Albumin peak</term><term>Antiadenovirus type</term><term>Biological activities</term><term>Capsomers</term><term>Centrifugation</term><term>Corresponding components</term><term>Different components</term><term>Different symbols</term><term>Different types</term><term>Dimer</term><term>Elution diagram</term><term>Erythrocyte</term><term>Erythrocyte absorptions</term><term>Exclusion chromatography</term><term>First absorption</term><term>Hexons</term><term>Intermediate strain</term><term>Latter samples</term><term>Norrby</term><term>Pentons</term><term>Physiological saline</term><term>Representative experiment</term><term>Sedimenting</term><term>Serotypes</term><term>Skaaret</term><term>Small quantities</term><term>Soluble</term><term>Soluble adenovirus</term><term>Soluble components</term><term>Sorrby</term><term>Speed centrifugation</term><term>Subgroup</term><term>Toxin</term><term>Toxin activity</term><term>Trypsin</term><term>Trypsin treatment</term><term>Vertex capsomers</term><term>Virion</term><term>Water bath</term><term>Zonal</term><term>Zonal centrifugation</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: The San Carlos agent, an adenovirus (type 3–16) sharing characteristics of type 3 by neutralization and of type 16 by hemagglutination inhibition (HI) tests, has been compared with types 3 and 16 with regard to physical-chemical properties of different structural components. No marked differences were found between the properties of isolated hexons, pentons (i.e., the incomplete hemagglutinin, HA, demonstrable in the presence of heterotypic immune sera), and fibers (i.e., the slowly sedimenting HI antibody-consuming components) of the three materials. However, the soluble complete HA's exhibited markedly different characteristics. The results indicate that they are carried by the following subunit aggregates: type 3—dodecahedral aggregates of pentons plus some extra structure; type 3–16—smaller polymers (probably dimers) of pentons; type 16—small polymers (probably dimers) of pentons or of fibers. Some members of Rosen's subgroup III (types 1, 2, 5, 6) show soluble complete HA subunit activities qualitatively similar to those of type 16.Soluble complete HA's containing small polymers of pentons were distinguished from those containing only fibers by the following properties; (a) a more rapid rate of sedimentation, (b) presence of toxin (cell-detachment) activity, (c) sensitivity to trypsin treatment, (d) presence of vertex capsomer antigen demonstrable by its hemagglutination enhancement antibody-consuming activity, and (e) a marked enhancement of the HA activity in the presence of heterotypic antisera.</div></front></TEI><affiliations><list><country><li>Suède</li></country><region><li>Comté de Stockholm</li><li>Svealand</li></region><settlement><li>Stockholm</li></settlement><orgName><li>Université de Stockholm</li></orgName></list><tree><country name="Suède"><region name="Svealand"><name sortKey="Norrby, Erling" sort="Norrby, Erling" uniqKey="Norrby E" first="Erling" last="Norrby">Erling Norrby</name></region><name sortKey="Skaaret, Per" sort="Skaaret, Per" uniqKey="Skaaret P" first="Per" last="Skaaret">Per Skaaret</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005228 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 005228 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:9C983233081CACF35D621CA2BAA14FC6289CF262
|texte= Comparison between soluble components of adenovirus types 3 and 16 and of the intermediate strain 3–16 (the San Carlos Agent)
}}
| This area was generated with Dilib version V0.6.33. |  |