Low concentrations of isoflurane abolish motor evoked responses to transcranial electrical stimulation during nitrous oxide/opioid anesthesia in humans.
Identifieur interne : 004871 ( Main/Exploration ); précédent : 004870; suivant : 004872Low concentrations of isoflurane abolish motor evoked responses to transcranial electrical stimulation during nitrous oxide/opioid anesthesia in humans.
Auteurs : C J Kalkman ; J C Drummond ; A A RibberinkSource :
- Anesthesia and analgesia [ 0003-2999 ] ; 1991.
Descripteurs français
- KwdFr :
- MESH :
- analogues et dérivés : Fentanyl.
- pharmacologie : Isoflurane.
- Adulte, Adulte d'âge moyen, Analgésiques, Anesthésie, Humains, Motoneurones, Protoxyde d'azote, Période peropératoire, Stimulation électrique, Sufentanil.
English descriptors
- KwdEn :
- MESH :
- chemical , analogs & derivatives : Fentanyl.
- chemical , pharmacology : Isoflurane.
- chemical : Analgesics, Nitrous Oxide, Sufentanil.
- drug effects : Motor Neurons.
- Adult, Anesthesia, Electric Stimulation, Humans, Intraoperative Period, Middle Aged.
Abstract
To study the feasibility of noninvasive monitoring of motor pathways in anesthetized patients, we evaluated the effect of isoflurane on motor evoked responses to constant-voltage transcranial electrical stimulation (tce-MERs). Reproducible tce-MERs were recordable from the tibialis anterior muscle during nitrous oxide/opioid anesthesia in 11 patients. Before the introduction of isoflurane, tce-MER onset latency was 30.8 +/- 1.9 ms, and amplitude ranged from 19 microV to 2.6 mV (median, 209 microV). Operating conditions necessitated neuromuscular blockade in three patients before administration of isoflurane. In the remaining eight patients, introduction of isoflurane in low concentrations resulted in an immediate increase in the latency and a decrease in the amplitude of tce-MERs. The tce-MERs were completely obliterated in all subjects at end-tidal isoflurane concentrations between 0.2% and 0.6% (median, 0.24%). After discontinuation of isoflurane, the tce-MER returned in all patients. The authors conclude that, during nitrous oxide/opioid anesthesia, with the stimulus and recording variables used, isoflurane even at very low concentrations precludes recording of tce-MERs.
DOI: 10.1213/00000539-199110000-00008
PubMed: 1832825
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 002981
- to stream PubMed, to step Curation: 002981
- to stream PubMed, to step Checkpoint: 002832
- to stream Ncbi, to step Merge: 000588
- to stream Ncbi, to step Curation: 000588
- to stream Ncbi, to step Checkpoint: 000588
- to stream Main, to step Merge: 004946
- to stream Main, to step Curation: 004871
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Low concentrations of isoflurane abolish motor evoked responses to transcranial electrical stimulation during nitrous oxide/opioid anesthesia in humans.</title>
<author><name sortKey="Kalkman, C J" sort="Kalkman, C J" uniqKey="Kalkman C" first="C J" last="Kalkman">C J Kalkman</name>
<affiliation><nlm:affiliation>Department of Anesthesiology, University of California, San Diego, La Jolla 92093-0629.</nlm:affiliation>
<wicri:noCountry code="subField">La Jolla 92093-0629</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Drummond, J C" sort="Drummond, J C" uniqKey="Drummond J" first="J C" last="Drummond">J C Drummond</name>
</author>
<author><name sortKey="Ribberink, A A" sort="Ribberink, A A" uniqKey="Ribberink A" first="A A" last="Ribberink">A A Ribberink</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="1991">1991</date>
<idno type="RBID">pubmed:1832825</idno>
<idno type="pmid">1832825</idno>
<idno type="doi">10.1213/00000539-199110000-00008</idno>
<idno type="wicri:Area/PubMed/Corpus">002981</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002981</idno>
<idno type="wicri:Area/PubMed/Curation">002981</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002981</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002832</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002832</idno>
<idno type="wicri:Area/Ncbi/Merge">000588</idno>
<idno type="wicri:Area/Ncbi/Curation">000588</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000588</idno>
<idno type="wicri:doubleKey">0003-2999:1991:Kalkman C:low:concentrations:of</idno>
<idno type="wicri:Area/Main/Merge">004946</idno>
<idno type="wicri:Area/Main/Curation">004871</idno>
<idno type="wicri:Area/Main/Exploration">004871</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Low concentrations of isoflurane abolish motor evoked responses to transcranial electrical stimulation during nitrous oxide/opioid anesthesia in humans.</title>
<author><name sortKey="Kalkman, C J" sort="Kalkman, C J" uniqKey="Kalkman C" first="C J" last="Kalkman">C J Kalkman</name>
<affiliation><nlm:affiliation>Department of Anesthesiology, University of California, San Diego, La Jolla 92093-0629.</nlm:affiliation>
<wicri:noCountry code="subField">La Jolla 92093-0629</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Drummond, J C" sort="Drummond, J C" uniqKey="Drummond J" first="J C" last="Drummond">J C Drummond</name>
</author>
<author><name sortKey="Ribberink, A A" sort="Ribberink, A A" uniqKey="Ribberink A" first="A A" last="Ribberink">A A Ribberink</name>
</author>
</analytic>
<series><title level="j">Anesthesia and analgesia</title>
<idno type="ISSN">0003-2999</idno>
<imprint><date when="1991" type="published">1991</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Analgesics</term>
<term>Anesthesia</term>
<term>Electric Stimulation</term>
<term>Fentanyl (analogs & derivatives)</term>
<term>Humans</term>
<term>Intraoperative Period</term>
<term>Isoflurane (pharmacology)</term>
<term>Middle Aged</term>
<term>Motor Neurons (drug effects)</term>
<term>Nitrous Oxide</term>
<term>Sufentanil</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Analgésiques</term>
<term>Anesthésie</term>
<term>Fentanyl (analogues et dérivés)</term>
<term>Humains</term>
<term>Isoflurane (pharmacologie)</term>
<term>Motoneurones ()</term>
<term>Protoxyde d'azote</term>
<term>Période peropératoire</term>
<term>Stimulation électrique</term>
<term>Sufentanil</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Fentanyl</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Isoflurane</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Analgesics</term>
<term>Nitrous Oxide</term>
<term>Sufentanil</term>
</keywords>
<keywords scheme="MESH" qualifier="analogues et dérivés" xml:lang="fr"><term>Fentanyl</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Motor Neurons</term>
</keywords>
<keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Isoflurane</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Anesthesia</term>
<term>Electric Stimulation</term>
<term>Humans</term>
<term>Intraoperative Period</term>
<term>Middle Aged</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Analgésiques</term>
<term>Anesthésie</term>
<term>Humains</term>
<term>Motoneurones</term>
<term>Protoxyde d'azote</term>
<term>Période peropératoire</term>
<term>Stimulation électrique</term>
<term>Sufentanil</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">To study the feasibility of noninvasive monitoring of motor pathways in anesthetized patients, we evaluated the effect of isoflurane on motor evoked responses to constant-voltage transcranial electrical stimulation (tce-MERs). Reproducible tce-MERs were recordable from the tibialis anterior muscle during nitrous oxide/opioid anesthesia in 11 patients. Before the introduction of isoflurane, tce-MER onset latency was 30.8 +/- 1.9 ms, and amplitude ranged from 19 microV to 2.6 mV (median, 209 microV). Operating conditions necessitated neuromuscular blockade in three patients before administration of isoflurane. In the remaining eight patients, introduction of isoflurane in low concentrations resulted in an immediate increase in the latency and a decrease in the amplitude of tce-MERs. The tce-MERs were completely obliterated in all subjects at end-tidal isoflurane concentrations between 0.2% and 0.6% (median, 0.24%). After discontinuation of isoflurane, the tce-MER returned in all patients. The authors conclude that, during nitrous oxide/opioid anesthesia, with the stimulus and recording variables used, isoflurane even at very low concentrations precludes recording of tce-MERs.</div>
</front>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Drummond, J C" sort="Drummond, J C" uniqKey="Drummond J" first="J C" last="Drummond">J C Drummond</name>
<name sortKey="Kalkman, C J" sort="Kalkman, C J" uniqKey="Kalkman C" first="C J" last="Kalkman">C J Kalkman</name>
<name sortKey="Ribberink, A A" sort="Ribberink, A A" uniqKey="Ribberink A" first="A A" last="Ribberink">A A Ribberink</name>
</noCountry>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004871 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 004871 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= MersV1 |flux= Main |étape= Exploration |type= RBID |clé= pubmed:1832825 |texte= Low concentrations of isoflurane abolish motor evoked responses to transcranial electrical stimulation during nitrous oxide/opioid anesthesia in humans. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:1832825" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a MersV1
This area was generated with Dilib version V0.6.33. |