Analysis of genetic variability of populations of herpes simplex viruses
Identifieur interne : 004594 ( Main/Exploration ); précédent : 004593; suivant : 004595Analysis of genetic variability of populations of herpes simplex viruses
Auteurs : Josém. Rojas [Espagne] ; Joaquín Dopazo [Espagne] ; Enrique Martín-Blanco [Espagne] ; Cecilio L Pez-Galíndez [Espagne] ; Enrique Tabarés [Espagne]Source :
- Virus Research [ 0168-1702 ] ; 1993.
English descriptors
- Teeft :
- Acad, Additional cleavage site, African swine fever virus, Anatomical origin, Brain biopsy, Branch lengths, Buchman, Bumhi, Cleavage, Different patients, Different strains, Differents groups, Endonuclease, Evolutionary pattern, Fusion fragment, Genetic, Genetic distances, Genetic variability, Genome, Herpes, Herpes simplex virus, Herpes simplex virus type, Herpes simplex viruses, Heterogeneity, Large number, Madrid, Molecular epidemiology, Molecular epidemiology studies, Mutation, Nucleotide, Nucleotide diversity index, Nucleotide sequences, Nucleotide site, Nucleotide substitutions, Original strains, Other hand, Pairwise distances, Phylip package, Phylogenetic, Phylogenetic analysis, Phylogenetic tree, Phylogenetic trees, Point mutations, Restriction, Restriction endonuclease analysis, Restriction endonuclease cleavage sites, Restriction endonucleases, Restriction maps, Restriction site, Restriction sites, Roizman, Sakaoka, Salud carlos, Simplex, Unique origin, Vero cells, Viral, Viral dnas, Virol.
Abstract
Abstract: An analysis of genetic variability of herpes simplex virus type 1 and type 2 populations of the Madrid (Spain) area has been carried out by digestion of viral DNA with restriction endonucleases. The index of nucleotide diversity indicated that herpes simplex virus type 1 has a slightly, although statistically significant, higher degree of heterogeneity than type 2. A phylogenetic tree for each type of virus has been constructed. The evolutionary pattern followed by both types of viruses (‘star-like’ topology) suggest that all the isolates analyzed evolved from a unique origin for each type of virus.
Url:
DOI: 10.1016/0168-1702(93)90025-I
Affiliations:
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The index of nucleotide diversity indicated that herpes simplex virus type 1 has a slightly, although statistically significant, higher degree of heterogeneity than type 2. A phylogenetic tree for each type of virus has been constructed. The evolutionary pattern followed by both types of viruses (‘star-like’ topology) suggest that all the isolates analyzed evolved from a unique origin for each type of virus.</div></front></TEI><affiliations><list><country><li>Espagne</li></country><region><li>Communauté de Madrid</li></region><settlement><li>Madrid</li></settlement><orgName><li>Université autonome de Madrid</li></orgName></list><tree><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Rojas, Josem" sort="Rojas, Josem" uniqKey="Rojas J" first="Josém." last="Rojas">Josém. Rojas</name></region><name sortKey="Dopazo, Joaquin" sort="Dopazo, Joaquin" uniqKey="Dopazo J" first="Joaquín" last="Dopazo">Joaquín Dopazo</name><name sortKey="L Pez Galindez, Cecilio" sort="L Pez Galindez, Cecilio" uniqKey="L Pez Galindez C" first="Cecilio" last="L Pez-Galíndez">Cecilio L Pez-Galíndez</name><name sortKey="Martin Blanco, Enrique" sort="Martin Blanco, Enrique" uniqKey="Martin Blanco E" first="Enrique" last="Martín-Blanco">Enrique Martín-Blanco</name><name sortKey="Tabares, Enrique" sort="Tabares, Enrique" uniqKey="Tabares E" first="Enrique" last="Tabarés">Enrique Tabarés</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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