Myasthenia gravis
Identifieur interne : 004560 ( Main/Exploration ); précédent : 004559; suivant : 004561Myasthenia gravis
Auteurs : Nick Willcox [Royaume-Uni]Source :
- Current Opinion in Immunology [ 0952-7915 ] ; 1993.
English descriptors
- Teeft :
- Acetylcholine, Acetylcholine receptor, Acetylcholine receptors, Achr, Achr subunits, Adjacent class, Ancestral haplotypes, Animal models, Antibody production, Antibody response, Autoantibody, Autoimmune, Autoimmune disease, Autoimmune responses, Basic research, Cell clones, Cell lines, Clin, Clone, Cytoplasmic loop, Eamg, Electric fish achr, Epithelial, Epitope, Genes encoding, Gravis, Helper type, High doses, Hong kong chinese, Human acetylcholine receptor, Human achr, Immunol, Imyasthenia gravis, Lymphocyte, Main immunogenic region, Major difficulties, Molecular medicine, Multiple sclerosis, Myasthenia, Myasthenia gravis, Myasthenia gravis patient, Myasthenia gravis patients, Negative selection, Nicotinic acetylcholine receptor, Pathogenic, Peptide, Peptides resident, Primary structure, Receptor, Scid mice, Second phase, Serum antibodies, Several groups, Several weeks, Striational autoantibodies, Subunit, Susceptibility locus, Synthetic peptides, Thymic, Thymic carcinoma, Thymoma, Thymoma patients, Thymus, Tumour, Tumour necrosis factor, Willcox.
Abstract
Abstract: The cause of the myasthenics' pathogenic autoantibody response against the muscle acetylcholine receptor is an intriguing puzzle involving the thymus and its epithelial tumours, and possibly a variety of cross-reacting epitopes. Another fascinating challenge is to find ways of selectively inhibiting this response in the patients.
Url:
DOI: 10.1016/0952-7915(93)90105-2
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 002023
- to stream Istex, to step Curation: 002023
- to stream Istex, to step Checkpoint: 001B71
- to stream Main, to step Merge: 004626
- to stream Main, to step Curation: 004560
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Myasthenia gravis</title>
<author><name sortKey="Willcox, Nick" sort="Willcox, Nick" uniqKey="Willcox N" first="Nick" last="Willcox">Nick Willcox</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:E0F9A53A22319E8D5566E40BCE365C6ADCA8266E</idno>
<date when="1993" year="1993">1993</date>
<idno type="doi">10.1016/0952-7915(93)90105-2</idno>
<idno type="url">https://api.istex.fr/ark:/67375/6H6-TK6G7XK5-8/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">002023</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002023</idno>
<idno type="wicri:Area/Istex/Curation">002023</idno>
<idno type="wicri:Area/Istex/Checkpoint">001B71</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">001B71</idno>
<idno type="wicri:Area/Main/Merge">004626</idno>
<idno type="wicri:Area/Main/Curation">004560</idno>
<idno type="wicri:Area/Main/Exploration">004560</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a">Myasthenia gravis</title>
<author><name sortKey="Willcox, Nick" sort="Willcox, Nick" uniqKey="Willcox N" first="Nick" last="Willcox">Nick Willcox</name>
<affiliation wicri:level="3"><country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Institute of Molecular Medicine, John Radcliffe Hospital, Oxford</wicri:regionArea>
<placeName><settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
</placeName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Current Opinion in Immunology</title>
<title level="j" type="abbrev">COIMMU</title>
<idno type="ISSN">0952-7915</idno>
<imprint><publisher>ELSEVIER</publisher>
<date type="published" when="1993">1993</date>
<biblScope unit="volume">5</biblScope>
<biblScope unit="issue">6</biblScope>
<biblScope unit="page" from="910">910</biblScope>
<biblScope unit="page" to="917">917</biblScope>
</imprint>
<idno type="ISSN">0952-7915</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0952-7915</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Acetylcholine</term>
<term>Acetylcholine receptor</term>
<term>Acetylcholine receptors</term>
<term>Achr</term>
<term>Achr subunits</term>
<term>Adjacent class</term>
<term>Ancestral haplotypes</term>
<term>Animal models</term>
<term>Antibody production</term>
<term>Antibody response</term>
<term>Autoantibody</term>
<term>Autoimmune</term>
<term>Autoimmune disease</term>
<term>Autoimmune responses</term>
<term>Basic research</term>
<term>Cell clones</term>
<term>Cell lines</term>
<term>Clin</term>
<term>Clone</term>
<term>Cytoplasmic loop</term>
<term>Eamg</term>
<term>Electric fish achr</term>
<term>Epithelial</term>
<term>Epitope</term>
<term>Genes encoding</term>
<term>Gravis</term>
<term>Helper type</term>
<term>High doses</term>
<term>Hong kong chinese</term>
<term>Human acetylcholine receptor</term>
<term>Human achr</term>
<term>Immunol</term>
<term>Imyasthenia gravis</term>
<term>Lymphocyte</term>
<term>Main immunogenic region</term>
<term>Major difficulties</term>
<term>Molecular medicine</term>
<term>Multiple sclerosis</term>
<term>Myasthenia</term>
<term>Myasthenia gravis</term>
<term>Myasthenia gravis patient</term>
<term>Myasthenia gravis patients</term>
<term>Negative selection</term>
<term>Nicotinic acetylcholine receptor</term>
<term>Pathogenic</term>
<term>Peptide</term>
<term>Peptides resident</term>
<term>Primary structure</term>
<term>Receptor</term>
<term>Scid mice</term>
<term>Second phase</term>
<term>Serum antibodies</term>
<term>Several groups</term>
<term>Several weeks</term>
<term>Striational autoantibodies</term>
<term>Subunit</term>
<term>Susceptibility locus</term>
<term>Synthetic peptides</term>
<term>Thymic</term>
<term>Thymic carcinoma</term>
<term>Thymoma</term>
<term>Thymoma patients</term>
<term>Thymus</term>
<term>Tumour</term>
<term>Tumour necrosis factor</term>
<term>Willcox</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Abstract: The cause of the myasthenics' pathogenic autoantibody response against the muscle acetylcholine receptor is an intriguing puzzle involving the thymus and its epithelial tumours, and possibly a variety of cross-reacting epitopes. Another fascinating challenge is to find ways of selectively inhibiting this response in the patients.</div>
</front>
</TEI>
<affiliations><list><country><li>Royaume-Uni</li>
</country>
<region><li>Angleterre</li>
<li>Oxfordshire</li>
</region>
<settlement><li>Oxford</li>
</settlement>
</list>
<tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Willcox, Nick" sort="Willcox, Nick" uniqKey="Willcox N" first="Nick" last="Willcox">Nick Willcox</name>
</region>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004560 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 004560 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= MersV1 |flux= Main |étape= Exploration |type= RBID |clé= ISTEX:E0F9A53A22319E8D5566E40BCE365C6ADCA8266E |texte= Myasthenia gravis }}
This area was generated with Dilib version V0.6.33. |