Biopolymer mimicry with polymeric wormlike micelles: Molecular weight scaled flexibility, locked‐in curvature, and coexisting microphases
Identifieur interne : 003176 ( Main/Exploration ); précédent : 003175; suivant : 003177Biopolymer mimicry with polymeric wormlike micelles: Molecular weight scaled flexibility, locked‐in curvature, and coexisting microphases
Auteurs : Paul Dalhaimer [États-Unis] ; Harry Bermudez [États-Unis] ; Dennis E. Discher [États-Unis]Source :
- Journal of Polymer Science Part B: Polymer Physics [ 0887-6266 ] ; 2004-01-01.
English descriptors
- Teeft :
- Actin cytoskeletons, Backbone traces, Bermudez, Bilayer, Bilayer vesicle, Bilayer vesicles, Biopolymer mimicry, Biopolymers, Blended worms, Butadiene bond, Contour length, Copolymer, Critical molar fraction, Crosslinked, Cytoskeletal, Diblock, Diblock copolymers, Discher, Discher figure, Glass slide, Hydrophobic, Hydrophobic chain, Hydrophobic core, Micelle, Mimicry, Molecular weight, Open circles, Open squares, Percolation, Percolation point, Persistence length, Persistence lengths, Phase diagram, Phys, Phys chem, Polymer, Polymer physics, Rigidity, Scale bars, Snapshot, Spherical micelles, Spontaneous curvature, Stiffness, Uorescence, Uorescence snapshots, Vesicle, Weight fraction, Wiley periodicals, Worm, Worm backbone, Worm diameter, Worm dynamics, Wormlike, Wormlike micelle, Wormlike micelles.
Abstract
Giant and stable wormlike micelles formed in water from a series of poly(ethylene oxide) (PEO)‐based diblock copolymer amphiphiles mimicked the flexibility of various cytoskeletal filaments. The worm diameter (d) was found by cryo‐transmission electron microscopy to scale with the length of the hydrophobic chain (Nh) of the copolymer as d ∼ Nh0.61. By fluorescence video imaging of worm dynamics, we also showed that the persistence length (lP) of wormlike micelles scaled as lP ∼ d2.8, consistent with a fluid aggregate (∼d3) rather than a solid rod (∼d4). By polymerizing the unsaturated bonds of assembled copolymers, fluid worms were converted to solid‐core worms, extending the bending rigidity from that of intermediate filament biopolymers to actin filaments and, in principle, microtubules. Through partial crosslinking, polymerized worms further locked in spontaneous curvature at a novel fluid‐to‐solid percolation point. The dynamics of distinct, branched conformations were also imaged for recently discovered Y‐junctioned wormlike micelles composed of diblocks of high molecular weight (>10–15 kg/mol). Finally, block copolymers of hydrophilic weight fraction close to the transition between a vesicle‐ and worm‐former assembled into both structures, allowing encapsulation of wormlike micelles in giant vesicles reminiscent of cytoskeletal filaments enclosed within cells. © 2003 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 42: 168–176, 2004
Url:
DOI: 10.1002/polb.10709
Affiliations:
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The worm diameter (d) was found by cryo‐transmission electron microscopy to scale with the length of the hydrophobic chain (Nh) of the copolymer as d ∼ Nh0.61. By fluorescence video imaging of worm dynamics, we also showed that the persistence length (lP) of wormlike micelles scaled as lP ∼ d2.8, consistent with a fluid aggregate (∼d3) rather than a solid rod (∼d4). By polymerizing the unsaturated bonds of assembled copolymers, fluid worms were converted to solid‐core worms, extending the bending rigidity from that of intermediate filament biopolymers to actin filaments and, in principle, microtubules. Through partial crosslinking, polymerized worms further locked in spontaneous curvature at a novel fluid‐to‐solid percolation point. The dynamics of distinct, branched conformations were also imaged for recently discovered Y‐junctioned wormlike micelles composed of diblocks of high molecular weight (>10–15 kg/mol). Finally, block copolymers of hydrophilic weight fraction close to the transition between a vesicle‐ and worm‐former assembled into both structures, allowing encapsulation of wormlike micelles in giant vesicles reminiscent of cytoskeletal filaments enclosed within cells. © 2003 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 42: 168–176, 2004</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Pennsylvanie</li></region></list><tree><country name="États-Unis"><region name="Pennsylvanie"><name sortKey="Dalhaimer, Paul" sort="Dalhaimer, Paul" uniqKey="Dalhaimer P" first="Paul" last="Dalhaimer">Paul Dalhaimer</name></region><name sortKey="Bermudez, Harry" sort="Bermudez, Harry" uniqKey="Bermudez H" first="Harry" last="Bermudez">Harry Bermudez</name><name sortKey="Discher, Dennis E" sort="Discher, Dennis E" uniqKey="Discher D" first="Dennis E." last="Discher">Dennis E. Discher</name><name sortKey="Discher, Dennis E" sort="Discher, Dennis E" uniqKey="Discher D" first="Dennis E." last="Discher">Dennis E. Discher</name><name sortKey="Discher, Dennis E" sort="Discher, Dennis E" uniqKey="Discher D" first="Dennis E." last="Discher">Dennis E. Discher</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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