Extracellular ribonucleic acids of human milk.
Identifieur interne : 003063 ( Main/Exploration ); précédent : 003062; suivant : 003064Extracellular ribonucleic acids of human milk.
Auteurs : Dmitry V. Semenov [Russie] ; Elena V. Kuligina ; Olesya N. Shevyrina ; Vladimir A. Richter ; Valentin V. VlassovSource :
- Annals of the New York Academy of Sciences [ 0077-8923 ] ; 2004.
Descripteurs français
- KwdFr :
- ARN (), ARN de transfert (analyse), ARN de transfert (métabolisme), ARN ribosomique (analyse), ARN ribosomique (métabolisme), ARN ribosomique 5.8S (analyse), ARN ribosomique 5.8S (métabolisme), Allaitement maternel, Dimérisation, Dénaturation d'acide nucléique, Facteurs temps, Femelle, Humains, Lactation, Lait humain (), Oligoribonucléotides (), Séquence nucléotidique, Électrophorèse bidimensionnelle sur gel.
- MESH :
- analyse : ARN de transfert, ARN ribosomique, ARN ribosomique 5.8S.
- métabolisme : ARN de transfert, ARN ribosomique, ARN ribosomique 5.8S.
- ARN, Allaitement maternel, Dimérisation, Dénaturation d'acide nucléique, Facteurs temps, Femelle, Humains, Lactation, Lait humain, Oligoribonucléotides, Séquence nucléotidique, Électrophorèse bidimensionnelle sur gel.
English descriptors
- KwdEn :
- Base Sequence, Breast Feeding, Dimerization, Electrophoresis, Gel, Two-Dimensional, Female, Humans, Lactation, Milk, Human (chemistry), Nucleic Acid Denaturation, Oligoribonucleotides (chemistry), RNA (chemistry), RNA, Ribosomal (analysis), RNA, Ribosomal (metabolism), RNA, Ribosomal, 5.8S (analysis), RNA, Ribosomal, 5.8S (metabolism), RNA, Transfer (analysis), RNA, Transfer (metabolism), Time Factors.
- MESH :
- chemical , analysis : RNA, Ribosomal, RNA, Ribosomal, 5.8S, RNA, Transfer.
- chemical , chemistry : Oligoribonucleotides, RNA.
- chemistry : Milk, Human.
- chemical , metabolism : RNA, Ribosomal, RNA, Ribosomal, 5.8S, RNA, Transfer.
- Base Sequence, Breast Feeding, Dimerization, Electrophoresis, Gel, Two-Dimensional, Female, Humans, Lactation, Nucleic Acid Denaturation, Time Factors.
Abstract
Human milk has been shown to contain heterogeneous oligoribonucleotides varying in size from dimers to 100 mers. The sets of long oligonucleotides in milk samples from different donors and from different stages of lactation have some conservative elements. Sequences of some RNA oligonucleotides correspond to the 3'-part of 5.8S human ribosomal RNA and to 3'-parts of tRNAVal and tRNATyr. Primary structures of other oligo-RNAs are homologous to fragments of human 18S and 28S rRNAs. Concentration of RNA in milk samples tends to decrease with lactation development. The change of RNA concentration and the low concentration of DNA in milk plasma suggest that the source of RNA in human milk may be active secretion of RNA by mammary gland cells.
DOI: 10.1196/annals.1318.029
PubMed: 15251959
Affiliations:
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Le document en format XML
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Shevyrina</name></author><author><name sortKey="Richter, Vladimir A" sort="Richter, Vladimir A" uniqKey="Richter V" first="Vladimir A" last="Richter">Vladimir A. Richter</name></author><author><name sortKey="Vlassov, Valentin V" sort="Vlassov, Valentin V" uniqKey="Vlassov V" first="Valentin V" last="Vlassov">Valentin V. 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Semenov</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, 630090, Russia. semenov@niboch.nsc.ru</nlm:affiliation><country xml:lang="fr">Russie</country><wicri:regionArea>Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, 630090</wicri:regionArea><wicri:noRegion>630090</wicri:noRegion></affiliation></author><author><name sortKey="Kuligina, Elena V" sort="Kuligina, Elena V" uniqKey="Kuligina E" first="Elena V" last="Kuligina">Elena V. Kuligina</name></author><author><name sortKey="Shevyrina, Olesya N" sort="Shevyrina, Olesya N" uniqKey="Shevyrina O" first="Olesya N" last="Shevyrina">Olesya N. Shevyrina</name></author><author><name sortKey="Richter, Vladimir A" sort="Richter, Vladimir A" uniqKey="Richter V" first="Vladimir A" last="Richter">Vladimir A. Richter</name></author><author><name sortKey="Vlassov, Valentin V" sort="Vlassov, Valentin V" uniqKey="Vlassov V" first="Valentin V" last="Vlassov">Valentin V. Vlassov</name></author></analytic><series><title level="j">Annals of the New York Academy of Sciences</title><idno type="ISSN">0077-8923</idno><imprint><date when="2004" type="published">2004</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Base Sequence</term><term>Breast Feeding</term><term>Dimerization</term><term>Electrophoresis, Gel, Two-Dimensional</term><term>Female</term><term>Humans</term><term>Lactation</term><term>Milk, Human (chemistry)</term><term>Nucleic Acid Denaturation</term><term>Oligoribonucleotides (chemistry)</term><term>RNA (chemistry)</term><term>RNA, Ribosomal (analysis)</term><term>RNA, Ribosomal (metabolism)</term><term>RNA, Ribosomal, 5.8S (analysis)</term><term>RNA, Ribosomal, 5.8S (metabolism)</term><term>RNA, Transfer (analysis)</term><term>RNA, Transfer (metabolism)</term><term>Time Factors</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ARN ()</term><term>ARN de transfert (analyse)</term><term>ARN de transfert (métabolisme)</term><term>ARN ribosomique (analyse)</term><term>ARN ribosomique (métabolisme)</term><term>ARN ribosomique 5.8S (analyse)</term><term>ARN ribosomique 5.8S (métabolisme)</term><term>Allaitement maternel</term><term>Dimérisation</term><term>Dénaturation d'acide nucléique</term><term>Facteurs temps</term><term>Femelle</term><term>Humains</term><term>Lactation</term><term>Lait humain ()</term><term>Oligoribonucléotides ()</term><term>Séquence nucléotidique</term><term>Électrophorèse bidimensionnelle sur gel</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>RNA, Ribosomal</term><term>RNA, Ribosomal, 5.8S</term><term>RNA, Transfer</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Oligoribonucleotides</term><term>RNA</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>ARN de transfert</term><term>ARN ribosomique</term><term>ARN ribosomique 5.8S</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Milk, Human</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>RNA, Ribosomal</term><term>RNA, Ribosomal, 5.8S</term><term>RNA, Transfer</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>ARN de transfert</term><term>ARN ribosomique</term><term>ARN ribosomique 5.8S</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Base Sequence</term><term>Breast Feeding</term><term>Dimerization</term><term>Electrophoresis, Gel, Two-Dimensional</term><term>Female</term><term>Humans</term><term>Lactation</term><term>Nucleic Acid Denaturation</term><term>Time Factors</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>ARN</term><term>Allaitement maternel</term><term>Dimérisation</term><term>Dénaturation d'acide nucléique</term><term>Facteurs temps</term><term>Femelle</term><term>Humains</term><term>Lactation</term><term>Lait humain</term><term>Oligoribonucléotides</term><term>Séquence nucléotidique</term><term>Électrophorèse bidimensionnelle sur gel</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Human milk has been shown to contain heterogeneous oligoribonucleotides varying in size from dimers to 100 mers. The sets of long oligonucleotides in milk samples from different donors and from different stages of lactation have some conservative elements. Sequences of some RNA oligonucleotides correspond to the 3'-part of 5.8S human ribosomal RNA and to 3'-parts of tRNAVal and tRNATyr. Primary structures of other oligo-RNAs are homologous to fragments of human 18S and 28S rRNAs. Concentration of RNA in milk samples tends to decrease with lactation development. The change of RNA concentration and the low concentration of DNA in milk plasma suggest that the source of RNA in human milk may be active secretion of RNA by mammary gland cells.</div></front></TEI><affiliations><list><country><li>Russie</li></country></list><tree><noCountry><name sortKey="Kuligina, Elena V" sort="Kuligina, Elena V" uniqKey="Kuligina E" first="Elena V" last="Kuligina">Elena V. Kuligina</name><name sortKey="Richter, Vladimir A" sort="Richter, Vladimir A" uniqKey="Richter V" first="Vladimir A" last="Richter">Vladimir A. Richter</name><name sortKey="Shevyrina, Olesya N" sort="Shevyrina, Olesya N" uniqKey="Shevyrina O" first="Olesya N" last="Shevyrina">Olesya N. Shevyrina</name><name sortKey="Vlassov, Valentin V" sort="Vlassov, Valentin V" uniqKey="Vlassov V" first="Valentin V" last="Vlassov">Valentin V. Vlassov</name></noCountry><country name="Russie"><noRegion><name sortKey="Semenov, Dmitry V" sort="Semenov, Dmitry V" uniqKey="Semenov D" first="Dmitry V" last="Semenov">Dmitry V. Semenov</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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