MersV1, Main, Exploration, bibRecord, 002A59

RNA expression analysis from formalin fixed paraffin embedded tissues

Identifieur interne : 002A59 ( Main/Exploration ); précédent : 002A58; suivant : 002A60

RNA expression analysis from formalin fixed paraffin embedded tissues

Auteurs : Susan M. Farragher [Royaume-Uni] ; Austin Tanney [Royaume-Uni] ; Richard D. Kennedy [Royaume-Uni] ; D. Paul Harkin [Royaume-Uni]

Source :

Histochemistry and Cell Biology [ 0948-6143 ] ; 2008-09-01.

RBID : ISTEX:3E4BF41DD19BC30AC9D4C629359A3476D10BF82D

English descriptors

KwdEn :
- FFPE, Gene expression, Microarray, Personalized medicine, RNA profiling.

Abstract

Abstract: Formalin fixation and paraffin embedding (FFPE) is the most commonly used method worldwide for tissue storage. This method preserves the tissue integrity but causes extensive damage to nucleic acids stored within the tissue. As methods for measuring gene expression such as RT-PCR and microarray are adopted into clinical practice there is an increasing necessity to access the wealth of information locked in the Formalin fixation and paraffin embedding archives. This paper reviews the progress in this field and discusses the unique opportunities that exist for the application of these techniques in the development of personalized medicine.

Url:

https://api.istex.fr/ark:/67375/VQC-6PGM7MZX-V/fulltext.pdf

DOI: 10.1007/s00418-008-0479-7

Affiliations:

Royaume-Uni

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Le document en format XML

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<front><div type="abstract" xml:lang="en">Abstract: Formalin fixation and paraffin embedding (FFPE) is the most commonly used method worldwide for tissue storage. This method preserves the tissue integrity but causes extensive damage to nucleic acids stored within the tissue. As methods for measuring gene expression such as RT-PCR and microarray are adopted into clinical practice there is an increasing necessity to access the wealth of information locked in the Formalin fixation and paraffin embedding archives. This paper reviews the progress in this field and discusses the unique opportunities that exist for the application of these techniques in the development of personalized medicine.</div>
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RNA expression analysis from formalin fixed paraffin embedded tissues

RNA expression analysis from formalin fixed paraffin embedded tissues

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri