Direct gene transfer with compacted DNA nanoparticles in retinal pigment epithelial cells: expression, repeat delivery and lack of toxicity.
Identifieur interne : 002261 ( Main/Exploration ); précédent : 002260; suivant : 002262Direct gene transfer with compacted DNA nanoparticles in retinal pigment epithelial cells: expression, repeat delivery and lack of toxicity.
Auteurs : Zongchao Han [États-Unis] ; Adarsha Koirala ; Rasha Makkia ; Mark J. Cooper ; Muna I. NaashSource :
- Nanomedicine (London, England) [ 1748-6963 ] ; 2012.
Descripteurs français
- KwdFr :
- ADN (administration et posologie), ADN (génétique), Animaux, Cellules épithéliales (métabolisme), Nanoparticules (), Nanoparticules (administration et posologie), Protéines à fluorescence verte (génétique), Protéines à fluorescence verte (métabolisme), Souris, Souris de lignée BALB C, Techniques de transfert de gènes, Épithélium pigmentaire de la rétine (cytologie).
- MESH :
- administration et posologie : ADN, Nanoparticules.
- cytologie : Épithélium pigmentaire de la rétine.
- génétique : ADN, Protéines à fluorescence verte.
- métabolisme : Cellules épithéliales, Protéines à fluorescence verte.
- Animaux, Nanoparticules, Souris, Souris de lignée BALB C, Techniques de transfert de gènes.
English descriptors
- KwdEn :
- Animals, DNA (administration & dosage), DNA (genetics), Epithelial Cells (metabolism), Gene Transfer Techniques, Green Fluorescent Proteins (genetics), Green Fluorescent Proteins (metabolism), Mice, Mice, Inbred BALB C, Nanoparticles (administration & dosage), Nanoparticles (chemistry), Retinal Pigment Epithelium (cytology).
- MESH :
- chemical , administration & dosage : DNA.
- chemical , genetics : DNA, Green Fluorescent Proteins.
- administration & dosage : Nanoparticles.
- chemistry : Nanoparticles.
- cytology : Retinal Pigment Epithelium.
- metabolism : Epithelial Cells, Green Fluorescent Proteins.
- Animals, Gene Transfer Techniques, Mice, Mice, Inbred BALB C.
Abstract
To evaluate the safety of compacted DNA nanoparticles (NPs) in retinal pigment epithelial (RPE) cells.
DOI: 10.2217/nnm.11.158
PubMed: 22356602
Affiliations:
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Le document en format XML
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Cooper</name></author><author><name sortKey="Naash, Muna I" sort="Naash, Muna I" uniqKey="Naash M" first="Muna I" last="Naash">Muna I. 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Cooper</name></author><author><name sortKey="Naash, Muna I" sort="Naash, Muna I" uniqKey="Naash M" first="Muna I" last="Naash">Muna I. 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Cooper</name><name sortKey="Koirala, Adarsha" sort="Koirala, Adarsha" uniqKey="Koirala A" first="Adarsha" last="Koirala">Adarsha Koirala</name><name sortKey="Makkia, Rasha" sort="Makkia, Rasha" uniqKey="Makkia R" first="Rasha" last="Makkia">Rasha Makkia</name><name sortKey="Naash, Muna I" sort="Naash, Muna I" uniqKey="Naash M" first="Muna I" last="Naash">Muna I. Naash</name></noCountry><country name="États-Unis"><region name="Oklahoma"><name sortKey="Han, Zongchao" sort="Han, Zongchao" uniqKey="Han Z" first="Zongchao" last="Han">Zongchao Han</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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