Serveur d'exploration MERS

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Family Cluster of Middle East Respiratory Syndrome Coronavirus Infections

Identifieur interne : 002188 ( Main/Exploration ); précédent : 002187; suivant : 002189

Family Cluster of Middle East Respiratory Syndrome Coronavirus Infections

Auteurs : Ziad A. Memish [Arabie saoudite] ; Alimuddin I. Zumla [Arabie saoudite, Royaume-Uni] ; Rafat F. Al-Hakeem [Arabie saoudite] ; Abdullah A. Al-Rabeeah [Arabie saoudite] ; Gwen M. Stephens [Arabie saoudite]

Source :

RBID : Pascal:13-0208927

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English descriptors

Abstract

A human coronavirus, called the Middle East respiratory syndrome coronavirus (MERS-CoV), was first identified in September 2012 in samples obtained from a Saudi Arabian businessman who died from acute respiratory failure. Since then, 49 cases of infections caused by MERS-CoV (previously called a novel coronavirus) with 26 deaths have been reported to date. In this report, we describe a family case cluster of MERS-CoV infection, including the clinical presentation, treatment outcomes, and household relationships of three young men who became ill with MERS-CoV infection after the hospitalization of an elderly male relative, who died of the disease. Twenty-four other family members living in the same household and 124 attending staff members at the hospitals did not become ill. MERS-CoV infection may cause a spectrum of clinical illness. Although an animal reservoir is suspected, none has been discovered. Meanwhile, global concern rests on the ability of MERS-CoV to cause major illness in close contacts of patients.


Affiliations:


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