Middle East Respiratory Syndrome Coronavirus “MERS-CoV”: Current Knowledge Gaps
Identifieur interne : 001686 ( Main/Exploration ); précédent : 001685; suivant : 001687Middle East Respiratory Syndrome Coronavirus “MERS-CoV”: Current Knowledge Gaps
Auteurs : G. R. Banik [Australie] ; G. Khandaker [Australie] ; H. Rashid [Australie]Source :
- Paediatric Respiratory Reviews [ 1526-0542 ] ; 2015.
Descripteurs français
- KwdFr :
- Animaux, Coronavirus du syndrome respiratoire du Moyen-Orient, Femelle, Humains, Infections à coronavirus (), Infections à coronavirus (diagnostic), Infections à coronavirus (virologie), Maladies de l'appareil respiratoire (), Maladies de l'appareil respiratoire (diagnostic), Maladies de l'appareil respiratoire (virologie), Mâle, Voyage.
- MESH :
- diagnostic : Infections à coronavirus, Maladies de l'appareil respiratoire.
- virologie : Infections à coronavirus, Maladies de l'appareil respiratoire.
- Animaux, Coronavirus du syndrome respiratoire du Moyen-Orient, Femelle, Humains, Infections à coronavirus, Maladies de l'appareil respiratoire, Mâle, Voyage.
English descriptors
- KwdEn :
- Animals, Coronavirus Infections (diagnosis), Coronavirus Infections (therapy), Coronavirus Infections (virology), Female, Humans, Male, Middle East Respiratory Syndrome Coronavirus, Respiratory Tract Diseases (diagnosis), Respiratory Tract Diseases (therapy), Respiratory Tract Diseases (virology), Travel.
- MESH :
- diagnosis : Coronavirus Infections, Respiratory Tract Diseases.
- therapy : Coronavirus Infections, Respiratory Tract Diseases.
- virology : Coronavirus Infections, Respiratory Tract Diseases.
- Animals, Female, Humans, Male, Middle East Respiratory Syndrome Coronavirus, Travel.
Abstract
The Middle East respiratory syndrome coronavirus (MERS-CoV) that causes a severe lower respiratory tract infection in humans is now considered a pandemic threat to the Gulf region. Since its discovery in 2012, MERS-CoV has reached 23 countries affecting about 1100 people, including a dozen children, and claiming over 400 lives. Compared to SARS (severe acute respiratory syndrome), MERS-CoV appears to kill more people (40% versus 10%), more quickly, and is especially more severe in those with pre-existing medical conditions. Most MERS-CoV cases (>85%) reported thus far have a history of residence in, or travel to the Middle East. The current epidemiology is characterised by slow and sustained transmission with occasional sparks. The dromedary camel is the intermediate host of MERS-CoV, but the transmission cycle is not fully understood. In this current review, we have briefly summarised the latest information on the epidemiology, clinical features, diagnosis, treatment and prevention of MERS-CoV especially highlighting the knowledge gaps in its transmission dynamics, diagnosis and preventive strategy.
Url:
DOI: 10.1016/j.prrv.2015.04.002
PubMed: 26002405
PubMed Central: 7106011
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en"><title>Summary</title>
<p>The Middle East respiratory syndrome coronavirus (MERS-CoV) that causes a severe lower respiratory tract infection in humans is now considered a pandemic threat to the Gulf region. Since its discovery in 2012, MERS-CoV has reached 23 countries affecting about 1100 people, including a dozen children, and claiming over 400 lives. Compared to SARS (severe acute respiratory syndrome), MERS-CoV appears to kill more people (40% versus 10%), more quickly, and is especially more severe in those with pre-existing medical conditions. Most MERS-CoV cases (>85%) reported thus far have a history of residence in, or travel to the Middle East. The current epidemiology is characterised by slow and sustained transmission with occasional sparks. The dromedary camel is the intermediate host of MERS-CoV, but the transmission cycle is not fully understood. In this current review, we have briefly summarised the latest information on the epidemiology, clinical features, diagnosis, treatment and prevention of MERS-CoV especially highlighting the knowledge gaps in its transmission dynamics, diagnosis and preventive strategy.</p>
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</TEI>
<affiliations><list><country><li>Australie</li>
</country>
<region><li>Nouvelle-Galles du Sud</li>
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<settlement><li>Sydney</li>
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<orgName><li>Université de Sydney</li>
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</record>
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