Pathogenicity and transmissibility of 2019-nCoV—A quick overview and comparison with other emerging viruses
Identifieur interne : 000121 ( Main/Exploration ); précédent : 000120; suivant : 000122Pathogenicity and transmissibility of 2019-nCoV—A quick overview and comparison with other emerging viruses
Auteurs : Jieliang ChenSource :
- Microbes and Infection [ 1286-4579 ] ; 2020.
Descripteurs français
- KwdFr :
- MESH :
- virologie : Infections à coronavirus, Pneumopathie virale.
- transmission : Humains, Infections à coronavirus, Nombre de reproduction de base, Pandémies, Pneumopathie virale, Virulence.
English descriptors
- KwdEn :
- MESH :
- pathogenicity : Betacoronavirus.
- transmission : Coronavirus Infections, Pneumonia, Viral.
- virology : Coronavirus Infections, Pneumonia, Viral.
- Basic Reproduction Number, Humans, Pandemics, Virulence.
Abstract
A zoonotic coronavirus, tentatively labeled as 2019-nCoV by the World Health Organization (WHO), has been identified as the causative agent of the viral pneumonia outbreak in Wuhan, China, at the end of 2019. Although 2019-nCoV can cause a severe respiratory illness like SARS and MERS, evidence from clinics suggested that 2019-nCoV is generally less pathogenic than SARS-CoV, and much less than MERS-CoV. The transmissibility of 2019-nCoV is still debated and needs to be further assessed. To avoid the 2019-nCoV outbreak turning into an epidemic or even a pandemic and to minimize the mortality rate, China activated emergency response procedures, but much remains to be learned about the features of the virus to refine the risk assessment and response. Here, the current knowledge in 2019-nCoV pathogenicity and transmissibility is summarized in comparison with several commonly known emerging viruses, and information urgently needed for a better control of the disease is highlighted.
Url:
DOI: 10.1016/j.micinf.2020.01.004
PubMed: 32032682
PubMed Central: 7102641
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000F23
- to stream Pmc, to step Curation: 000F23
- to stream Pmc, to step Checkpoint: 000048
- to stream PubMed, to step Corpus: 000249
- to stream PubMed, to step Curation: 000249
- to stream PubMed, to step Checkpoint: 000119
- to stream Ncbi, to step Merge: 002520
- to stream Ncbi, to step Curation: 002520
- to stream Ncbi, to step Checkpoint: 002520
- to stream Main, to step Merge: 000124
- to stream Main, to step Curation: 000121
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Pathogenicity and transmissibility of 2019-nCoV—A quick overview and comparison with other emerging viruses</title>
<author><name sortKey="Chen, Jieliang" sort="Chen, Jieliang" uniqKey="Chen J" first="Jieliang" last="Chen">Jieliang Chen</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">32032682</idno>
<idno type="pmc">7102641</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102641</idno>
<idno type="RBID">PMC:7102641</idno>
<idno type="doi">10.1016/j.micinf.2020.01.004</idno>
<date when="2020">2020</date>
<idno type="wicri:Area/Pmc/Corpus">000F23</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000F23</idno>
<idno type="wicri:Area/Pmc/Curation">000F23</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000F23</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000048</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000048</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:32032682</idno>
<idno type="wicri:Area/PubMed/Corpus">000249</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000249</idno>
<idno type="wicri:Area/PubMed/Curation">000249</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000249</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000119</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000119</idno>
<idno type="wicri:Area/Ncbi/Merge">002520</idno>
<idno type="wicri:Area/Ncbi/Curation">002520</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">002520</idno>
<idno type="wicri:doubleKey">1286-4579:2020:Chen J:pathogenicity:and:transmissibility</idno>
<idno type="wicri:Area/Main/Merge">000124</idno>
<idno type="wicri:Area/Main/Curation">000121</idno>
<idno type="wicri:Area/Main/Exploration">000121</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Pathogenicity and transmissibility of 2019-nCoV—A quick overview and comparison with other emerging viruses</title>
<author><name sortKey="Chen, Jieliang" sort="Chen, Jieliang" uniqKey="Chen J" first="Jieliang" last="Chen">Jieliang Chen</name>
</author>
</analytic>
<series><title level="j">Microbes and Infection</title>
<idno type="ISSN">1286-4579</idno>
<idno type="eISSN">1769-714X</idno>
<imprint><date when="2020">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Basic Reproduction Number</term>
<term>Betacoronavirus (pathogenicity)</term>
<term>Coronavirus Infections (transmission)</term>
<term>Coronavirus Infections (virology)</term>
<term>Humans</term>
<term>Pandemics</term>
<term>Pneumonia, Viral (transmission)</term>
<term>Pneumonia, Viral (virology)</term>
<term>Virulence</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Humains</term>
<term>Infections à coronavirus (transmission)</term>
<term>Infections à coronavirus (virologie)</term>
<term>Nombre de reproduction de base</term>
<term>Pandémies</term>
<term>Pneumopathie virale (transmission)</term>
<term>Pneumopathie virale (virologie)</term>
<term>Virulence</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Betacoronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections à coronavirus</term>
<term>Pneumopathie virale</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Basic Reproduction Number</term>
<term>Humans</term>
<term>Pandemics</term>
<term>Virulence</term>
</keywords>
<keywords scheme="MESH" qualifier="transmission" xml:lang="fr"><term>Humains</term>
<term>Infections à coronavirus</term>
<term>Nombre de reproduction de base</term>
<term>Pandémies</term>
<term>Pneumopathie virale</term>
<term>Virulence</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>A zoonotic coronavirus, tentatively labeled as 2019-nCoV by the World Health Organization (WHO), has been identified as the causative agent of the viral pneumonia outbreak in Wuhan, China, at the end of 2019. Although 2019-nCoV can cause a severe respiratory illness like SARS and MERS, evidence from clinics suggested that 2019-nCoV is generally less pathogenic than SARS-CoV, and much less than MERS-CoV. The transmissibility of 2019-nCoV is still debated and needs to be further assessed. To avoid the 2019-nCoV outbreak turning into an epidemic or even a pandemic and to minimize the mortality rate, China activated emergency response procedures, but much remains to be learned about the features of the virus to refine the risk assessment and response. Here, the current knowledge in 2019-nCoV pathogenicity and transmissibility is summarized in comparison with several commonly known emerging viruses, and information urgently needed for a better control of the disease is highlighted.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Who" uniqKey="Who">WHO</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wang, C" uniqKey="Wang C">C. Wang</name>
</author>
<author><name sortKey="Horby, P W" uniqKey="Horby P">P.W. Horby</name>
</author>
<author><name sortKey="Hayden, F G" uniqKey="Hayden F">F.G. Hayden</name>
</author>
<author><name sortKey="Gao, G F" uniqKey="Gao G">G.F. Gao</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Cui, J" uniqKey="Cui J">J. Cui</name>
</author>
<author><name sortKey="Li, F" uniqKey="Li F">F. Li</name>
</author>
<author><name sortKey="Shi, Z L" uniqKey="Shi Z">Z.L. Shi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="De Wit, E" uniqKey="De Wit E">E. de Wit</name>
</author>
<author><name sortKey="Van Doremalen, N" uniqKey="Van Doremalen N">N. van Doremalen</name>
</author>
<author><name sortKey="Falzarano, D" uniqKey="Falzarano D">D. Falzarano</name>
</author>
<author><name sortKey="Munster, V J" uniqKey="Munster V">V.J. Munster</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Huang, C" uniqKey="Huang C">C. Huang</name>
</author>
<author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name>
</author>
<author><name sortKey="Li, X" uniqKey="Li X">X. Li</name>
</author>
<author><name sortKey="Ren, L" uniqKey="Ren L">L. Ren</name>
</author>
<author><name sortKey="Zhao, J" uniqKey="Zhao J">J. Zhao</name>
</author>
<author><name sortKey="Hu, Y" uniqKey="Hu Y">Y. Hu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chan, J F W" uniqKey="Chan J">J.F.-W. Chan</name>
</author>
<author><name sortKey="Kok, K H" uniqKey="Kok K">K.-H. Kok</name>
</author>
<author><name sortKey="Zhu, Z" uniqKey="Zhu Z">Z. Zhu</name>
</author>
<author><name sortKey="Chu, H" uniqKey="Chu H">H. Chu</name>
</author>
<author><name sortKey="To, K K W" uniqKey="To K">K.K.-W. To</name>
</author>
<author><name sortKey="Yuan, S" uniqKey="Yuan S">S. Yuan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zhou, P" uniqKey="Zhou P">P. Zhou</name>
</author>
<author><name sortKey="Yang, X L" uniqKey="Yang X">X.-L. Yang</name>
</author>
<author><name sortKey="Wang, X G" uniqKey="Wang X">X.-G. Wang</name>
</author>
<author><name sortKey="Hu, B" uniqKey="Hu B">B. Hu</name>
</author>
<author><name sortKey="Zhang, L" uniqKey="Zhang L">L. Zhang</name>
</author>
<author><name sortKey="Zhang, W" uniqKey="Zhang W">W. Zhang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chan, J F W" uniqKey="Chan J">J.F.-W. Chan</name>
</author>
<author><name sortKey="Yuan, S" uniqKey="Yuan S">S. Yuan</name>
</author>
<author><name sortKey="Kok, K H" uniqKey="Kok K">K.-H. Kok</name>
</author>
<author><name sortKey="To, K K W" uniqKey="To K">K.K.-W. To</name>
</author>
<author><name sortKey="Chu, H" uniqKey="Chu H">H. Chu</name>
</author>
<author><name sortKey="Yang, J" uniqKey="Yang J">J. Yang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zhao, S" uniqKey="Zhao S">S. Zhao</name>
</author>
<author><name sortKey="Ran, J" uniqKey="Ran J">J. Ran</name>
</author>
<author><name sortKey="Musa, S S" uniqKey="Musa S">S.S. Musa</name>
</author>
<author><name sortKey="Yang, G" uniqKey="Yang G">G. Yang</name>
</author>
<author><name sortKey="Lou, Y" uniqKey="Lou Y">Y. Lou</name>
</author>
<author><name sortKey="Gao, D" uniqKey="Gao D">D. Gao</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bauch, C T" uniqKey="Bauch C">C.T. Bauch</name>
</author>
<author><name sortKey="Oraby, T" uniqKey="Oraby T">T. Oraby</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Read, J M" uniqKey="Read J">J.M. Read</name>
</author>
<author><name sortKey="Bridgen, J R" uniqKey="Bridgen J">J.R. Bridgen</name>
</author>
<author><name sortKey="Cummings, D A" uniqKey="Cummings D">D.A. Cummings</name>
</author>
<author><name sortKey="Ho, A" uniqKey="Ho A">A. Ho</name>
</author>
<author><name sortKey="Jewell, C P" uniqKey="Jewell C">C.P. Jewell</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Delamater, P L" uniqKey="Delamater P">P.L. Delamater</name>
</author>
<author><name sortKey="Street, E J" uniqKey="Street E">E.J. Street</name>
</author>
<author><name sortKey="Leslie, T F" uniqKey="Leslie T">T.F. Leslie</name>
</author>
<author><name sortKey="Yang, Y T" uniqKey="Yang Y">Y.T. Yang</name>
</author>
<author><name sortKey="Jacobsen, K H" uniqKey="Jacobsen K">K.H. Jacobsen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Shen, M" uniqKey="Shen M">M. Shen</name>
</author>
<author><name sortKey="Peng, Z" uniqKey="Peng Z">Z. Peng</name>
</author>
<author><name sortKey="Xiao, Y" uniqKey="Xiao Y">Y. Xiao</name>
</author>
<author><name sortKey="Zhang, L" uniqKey="Zhang L">L. Zhang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hamming, I" uniqKey="Hamming I">I. Hamming</name>
</author>
<author><name sortKey="Timens, W" uniqKey="Timens W">W. Timens</name>
</author>
<author><name sortKey="Bulthuis, M L" uniqKey="Bulthuis M">M.L. Bulthuis</name>
</author>
<author><name sortKey="Lely, A T" uniqKey="Lely A">A.T. Lely</name>
</author>
<author><name sortKey="Navis, G" uniqKey="Navis G">G. Navis</name>
</author>
<author><name sortKey="Van Goor, H" uniqKey="Van Goor H">H. van Goor</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Munster, V J" uniqKey="Munster V">V.J. Munster</name>
</author>
<author><name sortKey="Koopmans, M" uniqKey="Koopmans M">M. Koopmans</name>
</author>
<author><name sortKey="Van Doremalen, N" uniqKey="Van Doremalen N">N. van Doremalen</name>
</author>
<author><name sortKey="Van Riel, D" uniqKey="Van Riel D">D. van Riel</name>
</author>
<author><name sortKey="De Wit, E" uniqKey="De Wit E">E. de Wit</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Van Den Driessche, P" uniqKey="Van Den Driessche P">P. van den Driessche</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Jiang, S" uniqKey="Jiang S">S. Jiang</name>
</author>
<author><name sortKey="Du, L" uniqKey="Du L">L. Du</name>
</author>
<author><name sortKey="Shi, Z" uniqKey="Shi Z">Z. Shi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Yu, F" uniqKey="Yu F">F. Yu</name>
</author>
<author><name sortKey="Ojcis, D" uniqKey="Ojcis D">D. Ojcis</name>
</author>
<author><name sortKey="Pan, C" uniqKey="Pan C">C. Pan</name>
</author>
<author><name sortKey="Jiang, S" uniqKey="Jiang S">S. Jiang</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Chen, Jieliang" sort="Chen, Jieliang" uniqKey="Chen J" first="Jieliang" last="Chen">Jieliang Chen</name>
</noCountry>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000121 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000121 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= MersV1 |flux= Main |étape= Exploration |type= RBID |clé= PMC:7102641 |texte= Pathogenicity and transmissibility of 2019-nCoV—A quick overview and comparison with other emerging viruses }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:32032682" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a MersV1
This area was generated with Dilib version V0.6.33. |