Microevolution of Outbreak-Associated Middle East Respiratory Syndrome Coronavirus, South Korea, 2015.
Identifieur interne : 001142 ( Main/Curation ); précédent : 001141; suivant : 001143Microevolution of Outbreak-Associated Middle East Respiratory Syndrome Coronavirus, South Korea, 2015.
Auteurs : Moon-Woo Seong ; So Yeon Kim ; Victor Max Corman ; Taek Soo Kim ; Sung Im Cho ; Man Jin Kim ; Seung Jun Lee ; Jee-Soo Lee ; Soo Hyun Seo ; Ji Soo Ahn ; Byeong Su Yu ; Nare Park ; Myoung-Don Oh ; Wan Beom Park ; Ji Yeon Lee ; Gayeon Kim ; Joon Sung Joh ; Ina Jeong ; Eui Chong Kim ; Christian Drosten ; Sung Sup ParkSource :
- Emerging infectious diseases [ 1080-6059 ] ; 2016.
Descripteurs français
- KwdFr :
- Adulte, Coronavirus du syndrome respiratoire du Moyen-Orient (génétique), Coronavirus du syndrome respiratoire du Moyen-Orient (isolement et purification), Flambées de maladies, Génome viral, Histoire du 21ème siècle, Humains, Infections à coronavirus (histoire), Infections à coronavirus (transmission), Infections à coronavirus (virologie), Infections à coronavirus (épidémiologie), Mâle, République de Corée (épidémiologie), Variation génétique, Évolution moléculaire.
- MESH :
- génétique : Coronavirus du syndrome respiratoire du Moyen-Orient.
- histoire : Infections à coronavirus.
- isolement et purification : Coronavirus du syndrome respiratoire du Moyen-Orient.
- virologie : Infections à coronavirus.
- épidémiologie : Infections à coronavirus, République de Corée.
- Adulte, Flambées de maladies, Génome viral, Histoire du 21ème siècle, Humains, Mâle, Variation génétique, Évolution moléculaire.
English descriptors
- KwdEn :
- Adult, Coronavirus Infections (epidemiology), Coronavirus Infections (history), Coronavirus Infections (transmission), Coronavirus Infections (virology), Disease Outbreaks, Evolution, Molecular, Genetic Variation, Genome, Viral, History, 21st Century, Humans, Male, Middle East Respiratory Syndrome Coronavirus (genetics), Middle East Respiratory Syndrome Coronavirus (isolation & purification), Republic of Korea (epidemiology).
- MESH :
- epidemiology : Coronavirus Infections, Republic of Korea.
- genetics : Middle East Respiratory Syndrome Coronavirus.
- history : Coronavirus Infections.
- isolation & purification : Middle East Respiratory Syndrome Coronavirus.
- transmission : Coronavirus Infections.
- virology : Coronavirus Infections.
- Adult, Disease Outbreaks, Evolution, Molecular, Genetic Variation, Genome, Viral, History, 21st Century, Humans, Male.
Abstract
During the 2015 Middle East respiratory syndrome coronavirus outbreak in South Korea, we sequenced full viral genomes of strains isolated from 4 patients early and late during infection. Patients represented at least 4 generations of transmission. We found no evidence of changes in the evolutionary rate and no reason to suspect adaptive changes in viral proteins.
DOI: 10.3201/eid2202.151700
PubMed: 26814649
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pubmed:26814649Le document en format XML
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<term>Coronavirus Infections (transmission)</term>
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<term>Coronavirus du syndrome respiratoire du Moyen-Orient (isolement et purification)</term>
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<term>Histoire du 21ème siècle</term>
<term>Humains</term>
<term>Infections à coronavirus (histoire)</term>
<term>Infections à coronavirus (transmission)</term>
<term>Infections à coronavirus (virologie)</term>
<term>Infections à coronavirus (épidémiologie)</term>
<term>Mâle</term>
<term>République de Corée (épidémiologie)</term>
<term>Variation génétique</term>
<term>Évolution moléculaire</term>
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<front><div type="abstract" xml:lang="en">During the 2015 Middle East respiratory syndrome coronavirus outbreak in South Korea, we sequenced full viral genomes of strains isolated from 4 patients early and late during infection. Patients represented at least 4 generations of transmission. We found no evidence of changes in the evolutionary rate and no reason to suspect adaptive changes in viral proteins. </div>
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