Three-way and four-way junctions in DNA: a conformational viewpoint
Identifieur interne : 002553 ( Istex/Curation ); précédent : 002552; suivant : 002554Three-way and four-way junctions in DNA: a conformational viewpoint
Auteurs : Cornelis Altona [Pays-Bas] ; Jeroen A. Pikkemaat [Pays-Bas] ; Franc Jj Overmars [Pays-Bas]Source :
- Current Opinion in Structural Biology [ 0959-440X ] ; 1996.
English descriptors
- Teeft :
- Altona, Authors report, Backbone strands, Base pair, Base pairing, Base pairs, Base sequence, Base sequences, Biochemistry, Biol, Biological function, Biophys, Biophys biomol struct, Branch migration, Branch point, Capital letters, Central base pairs, Central residues, Centre, Chazin, Chemical attack, Chen chazin, Chen heffron, Clear preference, Coaxial, Coaxial base, Conformation, Conformational, Conformational analysis, Conformational aspects, Conformational choice, Conformational preference, Conformational selection, Conformational selectivity, Conformational viewpoint altona, Conformer, Conformer selection, Conformers, Continuous helical axes, Continuous strands, Critical amount, Direct evidence, Divalent ions, Double helices, Double helix, Duckett, Equimolar quantities, First time, Fluorescence resonance energy transfer, Fluorescence resonance energy transfer analysis, Further progress, Genetic recombination, Groove, Hairpin, Hairpin loop, Hairpin loops, Hela cells, Helical, Helical arms, Helix, Holliday, Holliday junction, Interhelical noes, International union, Interresidue noes, Ionic conditions, Ionic strength, Junction, Junction folds, Junctions exhibit, Junctions show, Kallenbach, Ladder motifs, Leontis, Lilley, Local conformation, Lond biol, Long arms, Magnesium, Magnesium ions, Migration, Minihairpin loops, Minor amount, Minor groove, Model compounds, Modelling study, Molecular biology, Molecular dynamics, More base pairs, Murchie, Mutual angle, Noesy spectra, Novel type, Nucleic, Nucleic acids, Other form, Other techniques, Overmars, Pikkemaat, Polyvalent, Polyvalent cations, Polyvalent ions, Proton, Proton resonances, Recombination, Relative orientation, Relative stabilities, Resonance assignments, Right angles, Salt conditions, Schematic representation, Seeman, Single strand, Single strands, Small angle, Solution structure, Spectroscopy, Spontaneous branch migration, Stacks, Stacks collinearly, Step time, Strand, Strand exchange, Strong preference, Structural biology, Sugar protons, Synthetic immobile holliday junctions, Tertiary constraints, Thymidine bases, Transition state, Twj1, Twj2.
Abstract
Abstract: DNA junctions are potential intermediates in various important genetic processes, including mutagenesis and recombination. The quantity of research carried out in this area is rapidly increasing. Examples of three-way and four-way junctions are now relatively well characterized and a few common properties have been recognized, of which the most important is the tendency of junctions to fold into one or more coaxially stacked helical conformations or cross-over structures.
Url:
DOI: 10.1016/S0959-440X(96)80048-0
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<profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Altona</term>
<term>Authors report</term>
<term>Backbone strands</term>
<term>Base pair</term>
<term>Base pairing</term>
<term>Base pairs</term>
<term>Base sequence</term>
<term>Base sequences</term>
<term>Biochemistry</term>
<term>Biol</term>
<term>Biological function</term>
<term>Biophys</term>
<term>Biophys biomol struct</term>
<term>Branch migration</term>
<term>Branch point</term>
<term>Capital letters</term>
<term>Central base pairs</term>
<term>Central residues</term>
<term>Centre</term>
<term>Chazin</term>
<term>Chemical attack</term>
<term>Chen chazin</term>
<term>Chen heffron</term>
<term>Clear preference</term>
<term>Coaxial</term>
<term>Coaxial base</term>
<term>Conformation</term>
<term>Conformational</term>
<term>Conformational analysis</term>
<term>Conformational aspects</term>
<term>Conformational choice</term>
<term>Conformational preference</term>
<term>Conformational selection</term>
<term>Conformational selectivity</term>
<term>Conformational viewpoint altona</term>
<term>Conformer</term>
<term>Conformer selection</term>
<term>Conformers</term>
<term>Continuous helical axes</term>
<term>Continuous strands</term>
<term>Critical amount</term>
<term>Direct evidence</term>
<term>Divalent ions</term>
<term>Double helices</term>
<term>Double helix</term>
<term>Duckett</term>
<term>Equimolar quantities</term>
<term>First time</term>
<term>Fluorescence resonance energy transfer</term>
<term>Fluorescence resonance energy transfer analysis</term>
<term>Further progress</term>
<term>Genetic recombination</term>
<term>Groove</term>
<term>Hairpin</term>
<term>Hairpin loop</term>
<term>Hairpin loops</term>
<term>Hela cells</term>
<term>Helical</term>
<term>Helical arms</term>
<term>Helix</term>
<term>Holliday</term>
<term>Holliday junction</term>
<term>Interhelical noes</term>
<term>International union</term>
<term>Interresidue noes</term>
<term>Ionic conditions</term>
<term>Ionic strength</term>
<term>Junction</term>
<term>Junction folds</term>
<term>Junctions exhibit</term>
<term>Junctions show</term>
<term>Kallenbach</term>
<term>Ladder motifs</term>
<term>Leontis</term>
<term>Lilley</term>
<term>Local conformation</term>
<term>Lond biol</term>
<term>Long arms</term>
<term>Magnesium</term>
<term>Magnesium ions</term>
<term>Migration</term>
<term>Minihairpin loops</term>
<term>Minor amount</term>
<term>Minor groove</term>
<term>Model compounds</term>
<term>Modelling study</term>
<term>Molecular biology</term>
<term>Molecular dynamics</term>
<term>More base pairs</term>
<term>Murchie</term>
<term>Mutual angle</term>
<term>Noesy spectra</term>
<term>Novel type</term>
<term>Nucleic</term>
<term>Nucleic acids</term>
<term>Other form</term>
<term>Other techniques</term>
<term>Overmars</term>
<term>Pikkemaat</term>
<term>Polyvalent</term>
<term>Polyvalent cations</term>
<term>Polyvalent ions</term>
<term>Proton</term>
<term>Proton resonances</term>
<term>Recombination</term>
<term>Relative orientation</term>
<term>Relative stabilities</term>
<term>Resonance assignments</term>
<term>Right angles</term>
<term>Salt conditions</term>
<term>Schematic representation</term>
<term>Seeman</term>
<term>Single strand</term>
<term>Single strands</term>
<term>Small angle</term>
<term>Solution structure</term>
<term>Spectroscopy</term>
<term>Spontaneous branch migration</term>
<term>Stacks</term>
<term>Stacks collinearly</term>
<term>Step time</term>
<term>Strand</term>
<term>Strand exchange</term>
<term>Strong preference</term>
<term>Structural biology</term>
<term>Sugar protons</term>
<term>Synthetic immobile holliday junctions</term>
<term>Tertiary constraints</term>
<term>Thymidine bases</term>
<term>Transition state</term>
<term>Twj1</term>
<term>Twj2</term>
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<front><div type="abstract" xml:lang="en">Abstract: DNA junctions are potential intermediates in various important genetic processes, including mutagenesis and recombination. The quantity of research carried out in this area is rapidly increasing. Examples of three-way and four-way junctions are now relatively well characterized and a few common properties have been recognized, of which the most important is the tendency of junctions to fold into one or more coaxially stacked helical conformations or cross-over structures.</div>
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