Genomic signatures: tracing the origin of retroelements at the nucleotide level
Identifieur interne : 000021 ( Istex/Curation ); précédent : 000020; suivant : 000022Genomic signatures: tracing the origin of retroelements at the nucleotide level
Auteurs : Christophe Terzian [France] ; Ivan Laprevotte [France] ; Sophie Brouillet [France] ; Alain Hénaut [France]Source :
- Genetica [ 0016-6707 ] ; 1997-03-01.
English descriptors
Abstract
Abstract: We investigate the nucleotide sequences of 23 retroelements (4 mammalian retroviruses, 1 human, 3 yeast, 2 plant, and 13 invertebrate retrotransposons) in terms of their oligonucleotide composition in order to address the problem of relationship between retrotransposons and retroviruses, and the coadaptation of these retroelements to their host genomes. We have identified by computer analysis over-represented 3- through 6-mers in each sequence. Our results indicate retrotransposons are heterogeneous in contrast to retroviruses, suggesting different modes of evolution by slippage-like mechanisms. Moreover, we have calculated the Observed/Expected number ratio for each of the 256 tetramers and analysed the data using a multivariate approach. The tetramer composition of retroelement sequences appears to be influenced by host genomic factors like methylase activity.
Url:
DOI: 10.1023/A:1018358301906
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000021
Links to Exploration step
ISTEX:A6C890D00A23FCC792DE92E1E0C57CBC4959C7F4Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Genomic signatures: tracing the origin of retroelements at the nucleotide level</title>
<author><name sortKey="Terzian, Christophe" sort="Terzian, Christophe" uniqKey="Terzian C" first="Christophe" last="Terzian">Christophe Terzian</name>
<affiliation wicri:level="1"><mods:affiliation>Centre de Génétique Moléculaire, CNRS, 91198, Gif-sur-Yvette, cedex, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Centre de Génétique Moléculaire, CNRS, 91198, Gif-sur-Yvette, cedex</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Laprevotte, Ivan" sort="Laprevotte, Ivan" uniqKey="Laprevotte I" first="Ivan" last="Laprevotte">Ivan Laprevotte</name>
<affiliation wicri:level="1"><mods:affiliation>Centre de Génétique Moléculaire, CNRS, 91198, Gif-sur-Yvette, cedex, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Centre de Génétique Moléculaire, CNRS, 91198, Gif-sur-Yvette, cedex</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brouillet, Sophie" sort="Brouillet, Sophie" uniqKey="Brouillet S" first="Sophie" last="Brouillet">Sophie Brouillet</name>
<affiliation wicri:level="1"><mods:affiliation>Centre de Génétique Moléculaire, CNRS, 91198, Gif-sur-Yvette, cedex, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Centre de Génétique Moléculaire, CNRS, 91198, Gif-sur-Yvette, cedex</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Henaut, Alain" sort="Henaut, Alain" uniqKey="Henaut A" first="Alain" last="Hénaut">Alain Hénaut</name>
<affiliation wicri:level="1"><mods:affiliation>Centre de Génétique Moléculaire, CNRS, 91198, Gif-sur-Yvette, cedex, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Centre de Génétique Moléculaire, CNRS, 91198, Gif-sur-Yvette, cedex</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:A6C890D00A23FCC792DE92E1E0C57CBC4959C7F4</idno>
<date when="1997" year="1997">1997</date>
<idno type="doi">10.1023/A:1018358301906</idno>
<idno type="url">https://api.istex.fr/ark:/67375/VQC-CG4P653T-L/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000021</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000021</idno>
<idno type="wicri:Area/Istex/Curation">000021</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Genomic signatures: tracing the origin of retroelements at the nucleotide level</title>
<author><name sortKey="Terzian, Christophe" sort="Terzian, Christophe" uniqKey="Terzian C" first="Christophe" last="Terzian">Christophe Terzian</name>
<affiliation wicri:level="1"><mods:affiliation>Centre de Génétique Moléculaire, CNRS, 91198, Gif-sur-Yvette, cedex, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Centre de Génétique Moléculaire, CNRS, 91198, Gif-sur-Yvette, cedex</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Laprevotte, Ivan" sort="Laprevotte, Ivan" uniqKey="Laprevotte I" first="Ivan" last="Laprevotte">Ivan Laprevotte</name>
<affiliation wicri:level="1"><mods:affiliation>Centre de Génétique Moléculaire, CNRS, 91198, Gif-sur-Yvette, cedex, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Centre de Génétique Moléculaire, CNRS, 91198, Gif-sur-Yvette, cedex</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Brouillet, Sophie" sort="Brouillet, Sophie" uniqKey="Brouillet S" first="Sophie" last="Brouillet">Sophie Brouillet</name>
<affiliation wicri:level="1"><mods:affiliation>Centre de Génétique Moléculaire, CNRS, 91198, Gif-sur-Yvette, cedex, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Centre de Génétique Moléculaire, CNRS, 91198, Gif-sur-Yvette, cedex</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Henaut, Alain" sort="Henaut, Alain" uniqKey="Henaut A" first="Alain" last="Hénaut">Alain Hénaut</name>
<affiliation wicri:level="1"><mods:affiliation>Centre de Génétique Moléculaire, CNRS, 91198, Gif-sur-Yvette, cedex, France</mods:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Centre de Génétique Moléculaire, CNRS, 91198, Gif-sur-Yvette, cedex</wicri:regionArea>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Genetica</title>
<title level="j" type="sub">An International Journal of Genetics and Evolution</title>
<title level="j" type="abbrev">Genetica</title>
<idno type="ISSN">0016-6707</idno>
<idno type="eISSN">1573-6857</idno>
<imprint><publisher>Kluwer Academic Publishers</publisher>
<pubPlace>Dordrecht</pubPlace>
<date type="published" when="1997-03-01">1997-03-01</date>
<biblScope unit="volume">100</biblScope>
<biblScope unit="issue">1-3</biblScope>
<biblScope unit="page" from="271">271</biblScope>
<biblScope unit="page" to="279">279</biblScope>
</imprint>
<idno type="ISSN">0016-6707</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0016-6707</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>multivariate analysis</term>
<term>oligonucleotide composition</term>
<term>retrotransposons</term>
<term>retroviruses</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Abstract: We investigate the nucleotide sequences of 23 retroelements (4 mammalian retroviruses, 1 human, 3 yeast, 2 plant, and 13 invertebrate retrotransposons) in terms of their oligonucleotide composition in order to address the problem of relationship between retrotransposons and retroviruses, and the coadaptation of these retroelements to their host genomes. We have identified by computer analysis over-represented 3- through 6-mers in each sequence. Our results indicate retrotransposons are heterogeneous in contrast to retroviruses, suggesting different modes of evolution by slippage-like mechanisms. Moreover, we have calculated the Observed/Expected number ratio for each of the 256 tetramers and analysed the data using a multivariate approach. The tetramer composition of retroelement sequences appears to be influenced by host genomic factors like methylase activity.</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Istex/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000021 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Curation/biblio.hfd -nk 000021 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= MersV1 |flux= Istex |étape= Curation |type= RBID |clé= ISTEX:A6C890D00A23FCC792DE92E1E0C57CBC4959C7F4 |texte= Genomic signatures: tracing the origin of retroelements at the nucleotide level }}
This area was generated with Dilib version V0.6.33. |