Biochip Platforms for DNA Diagnostics
Identifieur interne : 001C84 ( Istex/Corpus ); précédent : 001C83; suivant : 001C85Biochip Platforms for DNA Diagnostics
Auteurs : Anil K. Deisingh ; Adilah Guiseppi-Wilson ; Anthony Guiseppi-ElieSource :
- Integrated Analytical Systems
Abstract
Abstract: This chapter looks at the use of microlithographically fabricated biochip platforms for DNA diagnostics and prognostics, although protein and RNA biochips are also briefly considered. Biodetection methods such as ion-selective electrodes (ISEs), microelectromechanical systems (MEMS) devices such as microcantilevers, optical, piezoelectric-based acoustic wave, and mass spectrometry are briefly discussed. Emphasis is given to label-free electrochemical (impedimetric, voltammet-ric, and amperometric) detection. The production of DNA biochips is highlighted as are the operation and design of the experiments to reveal gene expression and SNP data. Applications discussed include the monitoring of microbes, cancer classification studies, and patient stratification in drug development. Finally, challenges and issues facing the development of diagnostic and prognostic biochips are discussed in detail.
Url:
DOI: 10.1007/978-0-387-72719-6_14
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ISTEX:CD179081CDC488032F6225355A7E8D87F7B2C771Le document en format XML
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Deisingh</name><affiliation><mods:affiliation>Center for Bioelectronics, Biosensors and Biochips (C3B), Department of Chemical and Biomolecular Engineering, Department of Bioengineering, Clemson University, 100, Technology Drive, 29625, Anderson, South Carolina, USA</mods:affiliation></affiliation></author><author><name sortKey="Guiseppi Wilson, Adilah" sort="Guiseppi Wilson, Adilah" uniqKey="Guiseppi Wilson A" first="Adilah" last="Guiseppi-Wilson">Adilah Guiseppi-Wilson</name><affiliation><mods:affiliation>ABTECH Scientific, Inc., 800 East Leigh Street, 23219, Richmond, Virginia, USA</mods:affiliation></affiliation></author><author><name sortKey="Guiseppi Elie, Anthony" sort="Guiseppi Elie, Anthony" uniqKey="Guiseppi Elie A" first="Anthony" last="Guiseppi-Elie">Anthony Guiseppi-Elie</name><affiliation><mods:affiliation>Center for Bioelectronics, Biosensors and Biochips (C3B), Department of Chemical and Biomolecular Engineering, Department of Bioengineering, Clemson University, 100, Technology Drive, 29625, Anderson, South Carolina, USA</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: guiseppi@clemson.edu</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:CD179081CDC488032F6225355A7E8D87F7B2C771</idno><date when="2009" year="2009">2009</date><idno type="doi">10.1007/978-0-387-72719-6_14</idno><idno type="url">https://api.istex.fr/ark:/67375/HCB-BXCHGN0V-L/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">001C84</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001C84</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Biochip Platforms for DNA Diagnostics</title><author><name sortKey="Deisingh, Anil K" sort="Deisingh, Anil K" uniqKey="Deisingh A" first="Anil K." last="Deisingh">Anil K. Deisingh</name><affiliation><mods:affiliation>Center for Bioelectronics, Biosensors and Biochips (C3B), Department of Chemical and Biomolecular Engineering, Department of Bioengineering, Clemson University, 100, Technology Drive, 29625, Anderson, South Carolina, USA</mods:affiliation></affiliation></author><author><name sortKey="Guiseppi Wilson, Adilah" sort="Guiseppi Wilson, Adilah" uniqKey="Guiseppi Wilson A" first="Adilah" last="Guiseppi-Wilson">Adilah Guiseppi-Wilson</name><affiliation><mods:affiliation>ABTECH Scientific, Inc., 800 East Leigh Street, 23219, Richmond, Virginia, USA</mods:affiliation></affiliation></author><author><name sortKey="Guiseppi Elie, Anthony" sort="Guiseppi Elie, Anthony" uniqKey="Guiseppi Elie A" first="Anthony" last="Guiseppi-Elie">Anthony Guiseppi-Elie</name><affiliation><mods:affiliation>Center for Bioelectronics, Biosensors and Biochips (C3B), Department of Chemical and Biomolecular Engineering, Department of Bioengineering, Clemson University, 100, Technology Drive, 29625, Anderson, South Carolina, USA</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: guiseppi@clemson.edu</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="s" type="main" xml:lang="en">Integrated Analytical Systems</title><title level="s" type="abbrev">Integrated Analytical Systems</title></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: This chapter looks at the use of microlithographically fabricated biochip platforms for DNA diagnostics and prognostics, although protein and RNA biochips are also briefly considered. 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Biodetection methods such as ion-selective electrodes (ISEs), microelectromechanical systems (MEMS) devices such as microcantilevers, optical, piezoelectric-based acoustic wave, and mass spectrometry are briefly discussed. Emphasis is given to label-free electrochemical (impedimetric, voltammet-ric, and amperometric) detection. The production of DNA biochips is highlighted as are the operation and design of the experiments to reveal gene expression and SNP data. Applications discussed include the monitoring of microbes, cancer classification studies, and patient stratification in drug development. Finally, challenges and issues facing the development of diagnostic and prognostic biochips are discussed in detail.</abstract><qualityIndicators><refBibsNative>false</refBibsNative><abstractWordCount>116</abstractWordCount><abstractCharCount>915</abstractCharCount><keywordCount>0</keywordCount><score>8.392</score><pdfWordCount>10349</pdfWordCount><pdfCharCount>67808</pdfCharCount><pdfVersion>1.3</pdfVersion><pdfPageCount>27</pdfPageCount><pdfPageSize>439.37 x 666.142 pts</pdfPageSize></qualityIndicators><title>Biochip Platforms for DNA Diagnostics</title><chapterId><json:string>14</json:string><json:string>Chap14</json:string></chapterId><genre><json:string>research-article</json:string></genre><serie><title>Integrated Analytical Systems</title><language><json:string>unknown</json:string></language><copyrightDate>2009</copyrightDate><volume>V</volume><editor><json:item><name>Radislav A. 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Raymond Ave., 91105, Pasadena, CA, USA</json:string><json:string>E-mail: Robin.Liu@osmetech.com</json:string></affiliations></json:item><json:item><name>Piotr Grodzinski</name><affiliations><json:string>National Institutes of Health National Cancer Institute, 31 Center Drive, 20892, Bethesda, MD, USA</json:string><json:string>E-mail: grodzinp@mail.nih.gov</json:string></affiliations></json:item></editor><subject><json:item><value>Chemistry and Materials Science</value></json:item><json:item><value>Chemistry</value></json:item><json:item><value>Analytical Chemistry</value></json:item><json:item><value>Biotechnology</value></json:item><json:item><value>Biochemical Engineering</value></json:item><json:item><value>Electrochemistry</value></json:item><json:item><value>Industrial Chemistry/Chemical Engineering</value></json:item><json:item><value>Characterization and Evaluation of Materials</value></json:item></subject></host><ark><json:string>ark:/67375/HCB-BXCHGN0V-L</json:string></ark><categories><inist><json:string>1 - 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Biodetection methods such as ion-selective electrodes (ISEs), microelectromechanical systems (MEMS) devices such as microcantilevers, optical, piezoelectric-based acoustic wave, and mass spectrometry are briefly discussed. Emphasis is given to label-free electrochemical (impedimetric, voltammet-ric, and amperometric) detection. The production of DNA biochips is highlighted as are the operation and design of the experiments to reveal gene expression and SNP data. Applications discussed include the monitoring of microbes, cancer classification studies, and patient stratification in drug development. 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TocLevels="0"><SeriesID>7427</SeriesID><SeriesTitle Language="En">Integrated Analytical Systems</SeriesTitle><SeriesAbbreviatedTitle>Integrated Analytical Systems</SeriesAbbreviatedTitle></SeriesInfo><SeriesHeader><EditorGroup><Editor AffiliationIDS="Aff10"><EditorName DisplayOrder="Western"><GivenName>Radislav</GivenName><GivenName>A.</GivenName><FamilyName>Potyailo</FamilyName></EditorName></Editor><Affiliation ID="Aff10"><OrgName>GE Global Research Center</OrgName><OrgAddress><City>Niskayana</City><Country>NY</Country></OrgAddress></Affiliation></EditorGroup></SeriesHeader><Book Language="En"><BookInfo BookProductType="Monograph" ContainsESM="No" Language="En" MediaType="eBook" NumberingStyle="ChapterOnly" TocLevels="0"><BookID>978-0-387-72719-6</BookID><BookTitle>Microarrays</BookTitle><BookSubTitle>Preparation, Microfluidics, Detection Methods, and Biological Applications</BookSubTitle><BookSequenceNumber>4</BookSequenceNumber><BookDOI>10.1007/978-0-387-72719-6</BookDOI><BookTitleID>137992</BookTitleID><BookPrintISBN>978-0-387-72716-5</BookPrintISBN><BookElectronicISBN>978-0-387-72719-6</BookElectronicISBN><BookChapterCount>17</BookChapterCount><BookCopyright><CopyrightHolderName>Springer-Verlag New York</CopyrightHolderName><CopyrightYear>2009</CopyrightYear></BookCopyright><BookSubjectGroup><BookSubject Code="C" Type="Primary">Chemistry</BookSubject><BookSubject Code="C11006" Priority="1" Type="Secondary">Analytical Chemistry</BookSubject><BookSubject Code="C12002" Priority="2" Type="Secondary">Biotechnology</BookSubject><BookSubject Code="C12029" Priority="3" Type="Secondary">Biochemical Engineering</BookSubject><BookSubject Code="C21010" Priority="4" Type="Secondary">Electrochemistry</BookSubject><BookSubject Code="C27000" Priority="5" Type="Secondary">Industrial Chemistry/Chemical Engineering</BookSubject><BookSubject Code="Z17000" Priority="6" Type="Secondary">Characterization and Evaluation of Materials</BookSubject><SubjectCollection Code="SUCO11644">Chemistry and Materials Science</SubjectCollection></BookSubjectGroup><BookContext><SeriesID>7427</SeriesID></BookContext></BookInfo><BookHeader><EditorGroup><Editor AffiliationIDS="Aff1"><EditorName DisplayOrder="Western"><GivenName>Kilian</GivenName><FamilyName>Dill</FamilyName></EditorName><Contact><Email>redwoodranch@yahoo.com</Email></Contact></Editor><Editor AffiliationIDS="Aff2"><EditorName DisplayOrder="Western"><GivenName>Robin</GivenName><GivenName>Hui</GivenName><FamilyName>Liu</FamilyName></EditorName><Contact><Email>Robin.Liu@osmetech.com</Email></Contact></Editor><Editor AffiliationIDS="Aff3"><EditorName DisplayOrder="Western"><GivenName>Piotr</GivenName><FamilyName>Grodzinski</FamilyName></EditorName><Contact><Email>grodzinp@mail.nih.gov</Email></Contact></Editor><Affiliation ID="Aff1"><OrgName>CombiMatrix Corporation, Inc. 6500 Harbour Heights Parkway</OrgName><OrgAddress><Street>Suite 301</Street><City>Mukilteo</City><State>WA</State><Postcode>98275</Postcode><Country>USA</Country></OrgAddress></Affiliation><Affiliation ID="Aff2"><OrgName>Osmetech Molecular Diagnostics</OrgName><OrgAddress><Street>757 S. Raymond Ave.</Street><City>Pasadena</City><State>CA</State><Postcode>91105</Postcode><Country>USA</Country></OrgAddress></Affiliation><Affiliation ID="Aff3"><OrgName>National Institutes of Health National Cancer Institute</OrgName><OrgAddress><Street>31 Center Drive</Street><City>Bethesda</City><State>MD</State><Postcode>20892</Postcode><Country>USA</Country></OrgAddress></Affiliation></EditorGroup></BookHeader><Part ID="Part5"><PartInfo TocLevels="0"><PartID>5</PartID><PartNumber>V</PartNumber><PartSequenceNumber>5</PartSequenceNumber><PartTitle>Future Improvements in Microarray Sensing</PartTitle><PartChapterCount>5</PartChapterCount></PartInfo><Chapter ID="Chap14" Language="En"><ChapterInfo ChapterType="OriginalPaper" ContainsESM="No" NumberingStyle="ChapterOnly" TocLevels="0"><ChapterID>14</ChapterID><ChapterNumber>14</ChapterNumber><ChapterDOI>10.1007/978-0-387-72719-6_14</ChapterDOI><ChapterSequenceNumber>14</ChapterSequenceNumber><ChapterTitle Language="En">Biochip Platforms for DNA Diagnostics</ChapterTitle><ChapterFirstPage>271</ChapterFirstPage><ChapterLastPage>297</ChapterLastPage><ChapterCopyright><CopyrightHolderName>Springer Science+Business Media, LLC</CopyrightHolderName><CopyrightYear>2009</CopyrightYear></ChapterCopyright><ChapterClassification><CharacteristicValue Characteristic="Keyword">Biochip Platforms for DNA Diagnostics</CharacteristicValue></ChapterClassification><ChapterGrants Type="Regular"><MetadataGrant Grant="OpenAccess"></MetadataGrant><AbstractGrant Grant="OpenAccess"></AbstractGrant><BodyPDFGrant Grant="Restricted"></BodyPDFGrant><BodyHTMLGrant Grant="Restricted"></BodyHTMLGrant><BibliographyGrant Grant="Restricted"></BibliographyGrant><ESMGrant Grant="Restricted"></ESMGrant></ChapterGrants></ChapterInfo><ChapterHeader><AuthorGroup><Author AffiliationIDS="Aff4_14"><AuthorName DisplayOrder="Western"><GivenName>Anil</GivenName><GivenName>K.</GivenName><FamilyName>Deisingh</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff5_14"><AuthorName DisplayOrder="Western"><GivenName>Adilah</GivenName><FamilyName>Guiseppi-Wilson</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff4_14"><AuthorName DisplayOrder="Western"><GivenName>Anthony</GivenName><FamilyName>Guiseppi-Elie</FamilyName></AuthorName><Contact><Email>guiseppi@clemson.edu</Email></Contact></Author><Affiliation ID="Aff4_14"><OrgDivision>Center for Bioelectronics, Biosensors and Biochips (C3B), Department of Chemical and Biomolecular Engineering, Department of Bioengineering</OrgDivision><OrgName>Clemson University, 100, Technology Drive</OrgName><OrgAddress><City>Anderson</City><State>South Carolina</State><Postcode>29625</Postcode><Country>USA</Country></OrgAddress></Affiliation><Affiliation ID="Aff5_14"><OrgName>ABTECH Scientific, Inc.</OrgName><OrgAddress><Street>800 East Leigh Street</Street><City>Richmond</City><State>Virginia</State><Postcode>23219</Postcode><Country>USA</Country></OrgAddress></Affiliation></AuthorGroup><Abstract ID="Abs1_14" Language="En"><Heading>Abstract</Heading><Para>This chapter looks at the use of microlithographically fabricated biochip platforms for DNA diagnostics and prognostics, although protein and RNA biochips are also briefly considered. Biodetection methods such as ion-selective electrodes (ISEs), microelectromechanical systems (MEMS) devices such as microcantilevers, optical, piezoelectric-based acoustic wave, and mass spectrometry are briefly discussed. Emphasis is given to label-free electrochemical (impedimetric, voltammet-ric, and amperometric) detection. The production of DNA biochips is highlighted as are the operation and design of the experiments to reveal gene expression and SNP data. Applications discussed include the monitoring of microbes, cancer classification studies, and patient stratification in drug development. Finally, challenges and issues facing the development of diagnostic and prognostic biochips are discussed in detail.</Para></Abstract></ChapterHeader><NoBody></NoBody></Chapter></Part></Book></Series></Publisher></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Biochip Platforms for DNA Diagnostics</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Biochip Platforms for DNA Diagnostics</title></titleInfo><name type="personal"><namePart type="given">Anil</namePart><namePart type="given">K.</namePart><namePart type="family">Deisingh</namePart><affiliation>Center for Bioelectronics, Biosensors and Biochips (C3B), Department of Chemical and Biomolecular Engineering, Department of Bioengineering, Clemson University, 100, Technology Drive, 29625, Anderson, South Carolina, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Adilah</namePart><namePart type="family">Guiseppi-Wilson</namePart><affiliation>ABTECH Scientific, Inc., 800 East Leigh Street, 23219, Richmond, Virginia, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Anthony</namePart><namePart type="family">Guiseppi-Elie</namePart><affiliation>Center for Bioelectronics, Biosensors and Biochips (C3B), Department of Chemical and Biomolecular Engineering, Department of Bioengineering, Clemson University, 100, Technology Drive, 29625, Anderson, South Carolina, USA</affiliation><affiliation>E-mail: guiseppi@clemson.edu</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre displayLabel="OriginalPaper" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" type="research-article" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</genre><originInfo><publisher>Springer New York</publisher><place><placeTerm type="text">New York, NY</placeTerm></place><dateIssued encoding="w3cdtf">2009</dateIssued><copyrightDate encoding="w3cdtf">2009</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><abstract lang="en">Abstract: This chapter looks at the use of microlithographically fabricated biochip platforms for DNA diagnostics and prognostics, although protein and RNA biochips are also briefly considered. Biodetection methods such as ion-selective electrodes (ISEs), microelectromechanical systems (MEMS) devices such as microcantilevers, optical, piezoelectric-based acoustic wave, and mass spectrometry are briefly discussed. Emphasis is given to label-free electrochemical (impedimetric, voltammet-ric, and amperometric) detection. The production of DNA biochips is highlighted as are the operation and design of the experiments to reveal gene expression and SNP data. Applications discussed include the monitoring of microbes, cancer classification studies, and patient stratification in drug development. Finally, challenges and issues facing the development of diagnostic and prognostic biochips are discussed in detail.</abstract><relatedItem type="host"><titleInfo><title>Microarrays</title><subTitle>Preparation, Microfluidics, Detection Methods, and Biological Applications</subTitle></titleInfo><name type="personal"><namePart type="given">Kilian</namePart><namePart type="family">Dill</namePart><affiliation>CombiMatrix Corporation, Inc. 6500 Harbour Heights Parkway, Suite 301, 98275, Mukilteo, WA, USA</affiliation><affiliation>E-mail: redwoodranch@yahoo.com</affiliation><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Robin</namePart><namePart type="given">Hui</namePart><namePart type="family">Liu</namePart><affiliation>Osmetech Molecular Diagnostics, 757 S. Raymond Ave., 91105, Pasadena, CA, USA</affiliation><affiliation>E-mail: Robin.Liu@osmetech.com</affiliation><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Piotr</namePart><namePart type="family">Grodzinski</namePart><affiliation>National Institutes of Health National Cancer Institute, 31 Center Drive, 20892, Bethesda, MD, USA</affiliation><affiliation>E-mail: grodzinp@mail.nih.gov</affiliation><role><roleTerm type="text">editor</roleTerm></role></name><genre type="book-series" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0G6R5W5T-Z">book-series</genre><originInfo><publisher>Springer</publisher><copyrightDate encoding="w3cdtf">2009</copyrightDate><issuance>monographic</issuance></originInfo><subject><genre>Book-Subject-Collection</genre><topic authority="SpringerSubjectCodes" authorityURI="SUCO11644">Chemistry and Materials Science</topic></subject><subject><genre>Book-Subject-Group</genre><topic authority="SpringerSubjectCodes" authorityURI="C">Chemistry</topic><topic authority="SpringerSubjectCodes" authorityURI="C11006">Analytical Chemistry</topic><topic authority="SpringerSubjectCodes" authorityURI="C12002">Biotechnology</topic><topic authority="SpringerSubjectCodes" authorityURI="C12029">Biochemical Engineering</topic><topic authority="SpringerSubjectCodes" authorityURI="C21010">Electrochemistry</topic><topic authority="SpringerSubjectCodes" authorityURI="C27000">Industrial Chemistry/Chemical Engineering</topic><topic authority="SpringerSubjectCodes" authorityURI="Z17000">Characterization and Evaluation of Materials</topic></subject><identifier type="DOI">10.1007/978-0-387-72719-6</identifier><identifier type="ISBN">978-0-387-72716-5</identifier><identifier type="eISBN">978-0-387-72719-6</identifier><identifier type="BookTitleID">137992</identifier><identifier type="BookID">978-0-387-72719-6</identifier><identifier type="BookChapterCount">17</identifier><identifier type="BookSequenceNumber">4</identifier><identifier type="PartChapterCount">5</identifier><part><date>2009</date><detail type="part"><title>V: Future Improvements in Microarray Sensing</title></detail><detail type="chapter"><number>14</number><caption>chapter</caption></detail><extent unit="pages"><start>271</start><end>297</end></extent></part><recordInfo><recordOrigin>Springer-Verlag New York, 2009</recordOrigin></recordInfo></relatedItem><relatedItem type="series"><titleInfo><title>Integrated Analytical Systems</title></titleInfo><name type="personal"><namePart type="given">Radislav</namePart><namePart type="given">A.</namePart><namePart type="family">Potyailo</namePart><affiliation>GE Global Research Center, Niskayana, NY</affiliation><role><roleTerm type="text">editor</roleTerm></role></name><originInfo><publisher>Springer</publisher><copyrightDate encoding="w3cdtf">2009</copyrightDate><issuance>serial</issuance></originInfo><identifier type="SeriesID">7427</identifier><part><detail type="volume"><number>V</number><caption>vol.</caption></detail><detail type="chapter"><number>14</number></detail></part><recordInfo><recordOrigin>Springer-Verlag New York, 2009</recordOrigin></recordInfo></relatedItem><identifier type="istex">CD179081CDC488032F6225355A7E8D87F7B2C771</identifier><identifier type="ark">ark:/67375/HCB-BXCHGN0V-L</identifier><identifier type="DOI">10.1007/978-0-387-72719-6_14</identifier><identifier type="ChapterID">14</identifier><identifier type="ChapterID">Chap14</identifier><accessCondition type="use and reproduction" contentType="copyright">Springer-Verlag New York, 2009</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-RLRX46XW-4">springer</recordContentSource><recordOrigin>Springer Science+Business Media, LLC, 2009</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/ark:/67375/HCB-BXCHGN0V-L/record.json</uri></json:item></metadata><annexes><json:item><extension>xml</extension><original>true</original><mimetype>application/xml</mimetype><uri>https://api.istex.fr/ark:/67375/HCB-BXCHGN0V-L/annexes.xml</uri></json:item></annexes></istex></record>Pour manipuler ce document sous Unix (Dilib)
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