Clusterin regulates vascular smooth muscle cell nodule formation and migration
Identifieur interne : 001C03 ( Istex/Corpus ); précédent : 001C02; suivant : 001C04Clusterin regulates vascular smooth muscle cell nodule formation and migration
Auteurs : Albert J. T. Millis ; Michael Luciani ; Heather M. Mccue ; Mark E. Rosenberg ; Casey L. MoulsonSource :
- Journal of Cellular Physiology [ 0021-9541 ] ; 2001-02.
Abstract
Vascular smooth muscle cells (VSMC) are the principal cellular component of the blood vessel wall where they exist in a differentiated state to maintain vascular tone. However, VSMC are not terminally differentiated and can be induced to dediffentiate, proliferate, and migrate. In fact, smooth muscle cell migration from the vascular wall into the lumen of the vessel is a central feature of occlusive vascular pathologies including atherosclerosis and intimal hyperplasia. In vitro, in the presence of an extracellular matrix, cultured vascular smooth muscle cells can migrate and invade the underlying gelatinous matrix, form multicellular nodular aggregations, and secrete the glycoprotein clusterin. Nodular cultures appear to mimic some of the properties of differentiated VSMC, in vivo. Here, to test the hypothesis that clusterin functions to modulate the formation of VSMC nodules and to facilitate cell migration a clusterin negative VSMC clone, SM‐CLU13AS (Moulson and Millis, 1999, J Cell Physiol 180:355), was transiently transfected with plasmid pRcCMVCLU that contains the full‐length porcine clusterin cDNA sequence under control of the CMV promoter. The transiently transfected VSMC culture expressed and secreted clusterin and formed nodules. To determine if clusterin regulates VSMC migration we used modified Boyden chamber assays. Clusterin, at 10 μg/ml, clearly promotes VSMC migration. In addition, a 15 amino acid synthetic peptide, representing amino acids 118–132 [KQTCMKFYARVCRSG] of the mature clusterin polypeptide, inhibits VSMC attachment to gelatinous substrate. Finally, clusterin appears to have a role in regulating endogenous clusterin expression in the clusterin negative clone. These results clearly establish that clusterin has functional role in VSMC nodule formation and support the conclusion that clusterin is a critical component of smooth muscle cell phenotypic modulation. J. Cell. Physiol. 186:210–219, 2001. © 2001 Wiley‐Liss, Inc.
Url:
DOI: 10.1002/1097-4652(200102)186:2<210::AID-JCP1019>3.0.CO;2-N
Links to Exploration step
ISTEX:BB776BE5D099364B5E02D9FCC7DAF7C3CEDE7A85Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Clusterin regulates vascular smooth muscle cell nodule formation and migration</title><author><name sortKey="Millis, Albert J T" sort="Millis, Albert J T" uniqKey="Millis A" first="Albert J. T." last="Millis">Albert J. T. Millis</name><affiliation><mods:affiliation>Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, Albany, New York</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: millis@csc.albany.edu</mods:affiliation></affiliation><affiliation><mods:affiliation>Correspondence address: Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, 1400 Washington Avenue, Albany, NY 12222.</mods:affiliation></affiliation></author><author><name sortKey="Luciani, Michael" sort="Luciani, Michael" uniqKey="Luciani M" first="Michael" last="Luciani">Michael Luciani</name><affiliation><mods:affiliation>Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, Albany, New York</mods:affiliation></affiliation></author><author><name sortKey="Mccue, Heather M" sort="Mccue, Heather M" uniqKey="Mccue H" first="Heather M." last="Mccue">Heather M. Mccue</name><affiliation><mods:affiliation>Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, Albany, New York</mods:affiliation></affiliation></author><author><name sortKey="Rosenberg, Mark E" sort="Rosenberg, Mark E" uniqKey="Rosenberg M" first="Mark E." last="Rosenberg">Mark E. Rosenberg</name><affiliation><mods:affiliation>Department of Medicine, University of Minnesota, Minneapolis, Minnesota</mods:affiliation></affiliation></author><author><name sortKey="Moulson, Casey L" sort="Moulson, Casey L" uniqKey="Moulson C" first="Casey L." last="Moulson">Casey L. Moulson</name><affiliation><mods:affiliation>Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, Albany, New York</mods:affiliation></affiliation><affiliation><mods:affiliation>Current Address: Renal Division, Washington University of St. Louis School of Medicine, 660 Euclid Avenue, St. Louis, MO 63110.</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:BB776BE5D099364B5E02D9FCC7DAF7C3CEDE7A85</idno><date when="2001" year="2001">2001</date><idno type="doi">10.1002/1097-4652(200102)186:2<210::AID-JCP1019>3.0.CO;2-N</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-9DRCK8TN-B/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">001C03</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001C03</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Clusterin regulates vascular smooth muscle cell nodule formation and migration</title><author><name sortKey="Millis, Albert J T" sort="Millis, Albert J T" uniqKey="Millis A" first="Albert J. T." last="Millis">Albert J. T. Millis</name><affiliation><mods:affiliation>Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, Albany, New York</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: millis@csc.albany.edu</mods:affiliation></affiliation><affiliation><mods:affiliation>Correspondence address: Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, 1400 Washington Avenue, Albany, NY 12222.</mods:affiliation></affiliation></author><author><name sortKey="Luciani, Michael" sort="Luciani, Michael" uniqKey="Luciani M" first="Michael" last="Luciani">Michael Luciani</name><affiliation><mods:affiliation>Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, Albany, New York</mods:affiliation></affiliation></author><author><name sortKey="Mccue, Heather M" sort="Mccue, Heather M" uniqKey="Mccue H" first="Heather M." last="Mccue">Heather M. Mccue</name><affiliation><mods:affiliation>Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, Albany, New York</mods:affiliation></affiliation></author><author><name sortKey="Rosenberg, Mark E" sort="Rosenberg, Mark E" uniqKey="Rosenberg M" first="Mark E." last="Rosenberg">Mark E. Rosenberg</name><affiliation><mods:affiliation>Department of Medicine, University of Minnesota, Minneapolis, Minnesota</mods:affiliation></affiliation></author><author><name sortKey="Moulson, Casey L" sort="Moulson, Casey L" uniqKey="Moulson C" first="Casey L." last="Moulson">Casey L. Moulson</name><affiliation><mods:affiliation>Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, Albany, New York</mods:affiliation></affiliation><affiliation><mods:affiliation>Current Address: Renal Division, Washington University of St. Louis School of Medicine, 660 Euclid Avenue, St. Louis, MO 63110.</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Journal of Cellular Physiology</title><title level="j" type="alt">JOURNAL OF CELLULAR PHYSIOLOGY</title><idno type="ISSN">0021-9541</idno><idno type="eISSN">1097-4652</idno><imprint><biblScope unit="vol">186</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="210">210</biblScope><biblScope unit="page" to="219">219</biblScope><biblScope unit="page-count">10</biblScope><publisher>John Wiley & Sons, Inc.</publisher><pubPlace>New York</pubPlace><date type="published" when="2001-02">2001-02</date></imprint><idno type="ISSN">0021-9541</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0021-9541</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Vascular smooth muscle cells (VSMC) are the principal cellular component of the blood vessel wall where they exist in a differentiated state to maintain vascular tone. However, VSMC are not terminally differentiated and can be induced to dediffentiate, proliferate, and migrate. In fact, smooth muscle cell migration from the vascular wall into the lumen of the vessel is a central feature of occlusive vascular pathologies including atherosclerosis and intimal hyperplasia. In vitro, in the presence of an extracellular matrix, cultured vascular smooth muscle cells can migrate and invade the underlying gelatinous matrix, form multicellular nodular aggregations, and secrete the glycoprotein clusterin. Nodular cultures appear to mimic some of the properties of differentiated VSMC, in vivo. Here, to test the hypothesis that clusterin functions to modulate the formation of VSMC nodules and to facilitate cell migration a clusterin negative VSMC clone, SM‐CLU13AS (Moulson and Millis, 1999, J Cell Physiol 180:355), was transiently transfected with plasmid pRcCMVCLU that contains the full‐length porcine clusterin cDNA sequence under control of the CMV promoter. The transiently transfected VSMC culture expressed and secreted clusterin and formed nodules. To determine if clusterin regulates VSMC migration we used modified Boyden chamber assays. Clusterin, at 10 μg/ml, clearly promotes VSMC migration. In addition, a 15 amino acid synthetic peptide, representing amino acids 118–132 [KQTCMKFYARVCRSG] of the mature clusterin polypeptide, inhibits VSMC attachment to gelatinous substrate. Finally, clusterin appears to have a role in regulating endogenous clusterin expression in the clusterin negative clone. These results clearly establish that clusterin has functional role in VSMC nodule formation and support the conclusion that clusterin is a critical component of smooth muscle cell phenotypic modulation. J. Cell. Physiol. 186:210–219, 2001. © 2001 Wiley‐Liss, Inc.</div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>clusterin</json:string><json:string>vsmc</json:string><json:string>millis</json:string><json:string>nodule</json:string><json:string>transfected</json:string><json:string>peptide</json:string><json:string>clone</json:string><json:string>porcine</json:string><json:string>biol</json:string><json:string>gelatin</json:string><json:string>transiently</json:string><json:string>receptor</json:string><json:string>antisense</json:string><json:string>moulson</json:string><json:string>mrna</json:string><json:string>chem</json:string><json:string>plasmid</json:string><json:string>glycoprotein</json:string><json:string>hybridization</json:string><json:string>transfection</json:string><json:string>diemer</json:string><json:string>vsmc migration</json:string><json:string>extracellular</json:string><json:string>silkensen</json:string><json:string>nodule formation</json:string><json:string>vascular smooth muscle cell</json:string><json:string>transiently transfected</json:string><json:string>vascular</json:string><json:string>gelatin substrate</json:string><json:string>clusterin expression</json:string><json:string>promoter</json:string><json:string>adhesion</json:string><json:string>nodular</json:string><json:string>amino</json:string><json:string>phenotypic modulation</json:string><json:string>transfected culture</json:string><json:string>life technology</json:string><json:string>smooth muscle cell</json:string><json:string>clusterin mrna</json:string><json:string>aggregation</json:string><json:string>assay</json:string><json:string>endogenous</json:string><json:string>matrix</json:string><json:string>western immunoassay</json:string><json:string>noncloned vsmc</json:string><json:string>vsmc nodule formation</json:string><json:string>room temperature</json:string><json:string>synthetic peptide</json:string><json:string>biol chem</json:string><json:string>boehringer mannheim</json:string><json:string>vascular muscle cell</json:string><json:string>culture morphology</json:string><json:string>recombinant clusterin</json:string><json:string>cell migration</json:string><json:string>endogenous clusterin</json:string><json:string>dose response</json:string><json:string>nodular culture</json:string><json:string>cell adhesion</json:string><json:string>cell death</json:string><json:string>clusterin peptide</json:string><json:string>plastic substrate</json:string><json:string>peptide concentration</json:string><json:string>cultured vsmc</json:string><json:string>porcine clusterin cdna sequence</json:string><json:string>form nodule</json:string><json:string>migration</json:string></teeft></keywords><author><json:item><name>Albert J.T. Millis</name><affiliations><json:string>Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, Albany, New York</json:string><json:string>E-mail: millis@csc.albany.edu</json:string><json:string>Correspondence address: Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, 1400 Washington Avenue, Albany, NY 12222.</json:string></affiliations></json:item><json:item><name>Michael Luciani</name><affiliations><json:string>Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, Albany, New York</json:string></affiliations></json:item><json:item><name>Heather M. McCue</name><affiliations><json:string>Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, Albany, New York</json:string></affiliations></json:item><json:item><name>Mark E. Rosenberg</name><affiliations><json:string>Department of Medicine, University of Minnesota, Minneapolis, Minnesota</json:string></affiliations></json:item><json:item><name>Casey L. Moulson</name><affiliations><json:string>Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, Albany, New York</json:string><json:string>Current Address: Renal Division, Washington University of St. Louis School of Medicine, 660 Euclid Avenue, St. Louis, MO 63110.</json:string></affiliations></json:item></author><articleId><json:string>JCP1019</json:string></articleId><arkIstex>ark:/67375/WNG-9DRCK8TN-B</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>Vascular smooth muscle cells (VSMC) are the principal cellular component of the blood vessel wall where they exist in a differentiated state to maintain vascular tone. However, VSMC are not terminally differentiated and can be induced to dediffentiate, proliferate, and migrate. In fact, smooth muscle cell migration from the vascular wall into the lumen of the vessel is a central feature of occlusive vascular pathologies including atherosclerosis and intimal hyperplasia. In vitro, in the presence of an extracellular matrix, cultured vascular smooth muscle cells can migrate and invade the underlying gelatinous matrix, form multicellular nodular aggregations, and secrete the glycoprotein clusterin. Nodular cultures appear to mimic some of the properties of differentiated VSMC, in vivo. Here, to test the hypothesis that clusterin functions to modulate the formation of VSMC nodules and to facilitate cell migration a clusterin negative VSMC clone, SM‐CLU13AS (Moulson and Millis, 1999, J Cell Physiol 180:355), was transiently transfected with plasmid pRcCMVCLU that contains the full‐length porcine clusterin cDNA sequence under control of the CMV promoter. The transiently transfected VSMC culture expressed and secreted clusterin and formed nodules. To determine if clusterin regulates VSMC migration we used modified Boyden chamber assays. Clusterin, at 10 μg/ml, clearly promotes VSMC migration. In addition, a 15 amino acid synthetic peptide, representing amino acids 118–132 [KQTCMKFYARVCRSG] of the mature clusterin polypeptide, inhibits VSMC attachment to gelatinous substrate. Finally, clusterin appears to have a role in regulating endogenous clusterin expression in the clusterin negative clone. These results clearly establish that clusterin has functional role in VSMC nodule formation and support the conclusion that clusterin is a critical component of smooth muscle cell phenotypic modulation. J. Cell. Physiol. 186:210–219, 2001. © 2001 Wiley‐Liss, Inc.</abstract><qualityIndicators><score>10</score><pdfWordCount>6066</pdfWordCount><pdfCharCount>39040</pdfCharCount><pdfVersion>1.2</pdfVersion><pdfPageCount>10</pdfPageCount><pdfPageSize>592 x 789 pts</pdfPageSize><pdfWordsPerPage>607</pdfWordsPerPage><pdfText>true</pdfText><refBibsNative>true</refBibsNative><abstractWordCount>280</abstractWordCount><abstractCharCount>1979</abstractCharCount><keywordCount>0</keywordCount></qualityIndicators><title>Clusterin regulates vascular smooth muscle cell nodule formation and migration</title><genre><json:string>article</json:string></genre><host><title>Journal of Cellular Physiology</title><language><json:string>unknown</json:string></language><doi><json:string>10.1002/(ISSN)1097-4652</json:string></doi><issn><json:string>0021-9541</json:string></issn><eissn><json:string>1097-4652</json:string></eissn><publisherId><json:string>JCP</json:string></publisherId><volume>186</volume><issue>2</issue><pages><first>210</first><last>219</last><total>10</total></pages><genre><json:string>journal</json:string></genre><subject><json:item><value>Original Article</value></json:item><json:item><value>Original Articles</value></json:item></subject></host><namedEntities><unitex><date><json:string>2001</json:string><json:string>1990</json:string></date><geogName></geogName><orgName><json:string>Microsoft Corporation, Redmond</json:string><json:string>Ohio State University</json:string><json:string>Washington University</json:string><json:string>Washington State University</json:string><json:string>Millis, Center for Comparative Functional Genomics</json:string><json:string>Life Technologies</json:string><json:string>Life Technologies, Inc.</json:string><json:string>Amersham Corporation</json:string><json:string>Universal Imaging Corporation</json:string><json:string>University of Minnesota</json:string><json:string>Wiley-Liss, Inc.</json:string><json:string>University of Cincinnati Medical Center</json:string><json:string>Department of Biological Sciences, University</json:string><json:string>Baxter Healthcare Corporation</json:string><json:string>Life Technologies Inc.</json:string><json:string>National Heart, Lung, and Blood Institute, National Institutes of Health</json:string><json:string>LISS, INC.</json:string><json:string>Neuro Probe Inc.</json:string><json:string>Department of Medicine, University of Minnesota, Minneapolis, Minnesota Vascular</json:string></orgName><orgName_funder></orgName_funder><orgName_provider></orgName_provider><persName><json:string>J. Cell</json:string><json:string>Cabin John</json:string><json:string>B. Considered</json:string><json:string>Judy Harmony</json:string><json:string>Michael Griswold</json:string><json:string>Louis School</json:string><json:string>Facility</json:string><json:string>Pamela HawleyNelson</json:string><json:string>To</json:string><json:string>Nat Acad</json:string><json:string>Washington Avenue</json:string><json:string>La Jolla</json:string><json:string>Arthur Strauch</json:string><json:string>A. Cultures</json:string><json:string>Dev Biol</json:string><json:string>Falcon Plastics</json:string></persName><placeName><json:string>Bedford</json:string><json:string>Minneapolis</json:string><json:string>Lund</json:string><json:string>IL</json:string><json:string>NY</json:string><json:string>Columbus</json:string><json:string>Albany</json:string><json:string>Mannheim</json:string><json:string>Cincinnati</json:string><json:string>MD</json:string><json:string>Puri</json:string><json:string>Pullman</json:string><json:string>Rockville</json:string><json:string>York</json:string><json:string>MA</json:string><json:string>WA</json:string><json:string>OH.</json:string><json:string>Arlington Heights</json:string><json:string>MN</json:string><json:string>Chester</json:string><json:string>OH</json:string><json:string>Grand Island</json:string></placeName><ref_url></ref_url><ref_bibl><json:string>Schwartz and Liaw, 1993</json:string><json:string>Watson et al., 1994</json:string><json:string>Benditt et al., 1983</json:string><json:string>Buttyan et al., 1989</json:string><json:string>Giambrone and Cotran, 1975</json:string><json:string>Moulson and Millis, 1999</json:string><json:string>Ross, 1993</json:string><json:string>Witte et al., 1993</json:string><json:string>Kounnas et al., 1995</json:string><json:string>Yamamoto and Yamamoto, 1994</json:string><json:string>Kyprianou et al., 1990</json:string><json:string>ThomasSalgar and Millis, 1994</json:string><json:string>Pauley et al., 1992</json:string><json:string>Shackelton et al., 1995</json:string><json:string>Hartmann et al., 1991</json:string><json:string>Bostrom et al., 1993</json:string><json:string>Collard and Griswold, 1987</json:string><json:string>Owens, 1995</json:string><json:string>Diemer et al., 1992</json:string><json:string>Cockerill et al., 1995</json:string><json:string>Tung et al., 1992</json:string><json:string>Aronow et al., 1993</json:string><json:string>Blaschuk et al., 1983</json:string><json:string>Faris et al., 1992</json:string><json:string>Ivaska et al., 1999</json:string><json:string>Montgomery et al., 1994</json:string><json:string>Hedin and Thyberg, 1987</json:string><json:string>Brennan et al., 1983</json:string><json:string>Burkey et al., 1991</json:string><json:string>Mackness et al., 1997</json:string><json:string>Silkensen et al., 1995</json:string><json:string>Montesano et al., 1998</json:string><json:string>Brennan et al., 1982</json:string><json:string>Shanahan et al., 1993</json:string><json:string>Thomas-Salgar and Millis, 1994</json:string><json:string>Ishikawa et al., 1998</json:string><json:string>Thyberg et al., 1990</json:string><json:string>Lee et al., 1995</json:string><json:string>Skinner et al., 1994</json:string><json:string>Malinda et al., 1999</json:string><json:string>Silkensen et al., 1999</json:string><json:string>Mahon et al., 1999</json:string></ref_bibl><bibl></bibl></unitex></namedEntities><ark><json:string>ark:/67375/WNG-9DRCK8TN-B</json:string></ark><categories><wos><json:string>1 - science</json:string><json:string>2 - physiology</json:string><json:string>2 - cell biology</json:string></wos><scienceMetrix><json:string>1 - health sciences</json:string><json:string>2 - biomedical research</json:string><json:string>3 - biochemistry & molecular biology</json:string></scienceMetrix><scopus><json:string>1 - Life Sciences</json:string><json:string>2 - Biochemistry, Genetics and Molecular Biology</json:string><json:string>3 - Cell Biology</json:string><json:string>1 - Life Sciences</json:string><json:string>2 - Biochemistry, Genetics and Molecular Biology</json:string><json:string>3 - Clinical Biochemistry</json:string><json:string>1 - Life Sciences</json:string><json:string>2 - Biochemistry, Genetics and Molecular Biology</json:string><json:string>3 - Physiology</json:string></scopus><inist><json:string>1 - sciences appliquees, technologies et medecines</json:string><json:string>2 - sciences biologiques et medicales</json:string><json:string>3 - sciences medicales</json:string></inist></categories><publicationDate>2001</publicationDate><copyrightDate>2001</copyrightDate><doi><json:string>10.1002/1097-4652(200102)186:2>210::AID-JCP1019>3.0.CO;2-N</json:string></doi><id>BB776BE5D099364B5E02D9FCC7DAF7C3CEDE7A85</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-9DRCK8TN-B/fulltext.pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-9DRCK8TN-B/bundle.zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/ark:/67375/WNG-9DRCK8TN-B/fulltext.tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main">Clusterin regulates vascular smooth muscle cell nodule formation and migration</title><title level="a" type="short" xml:lang="en">Clusterin Regulates Vascular Muscle Cells</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>John Wiley & Sons, Inc.</publisher><pubPlace>New York</pubPlace><availability><licence>Copyright © 2001 Wiley‐Liss, Inc.</licence></availability><date type="published" when="2001-02"></date></publicationStmt><notesStmt><note type="content-type" subtype="article" source="article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="article"><analytic><title level="a" type="main">Clusterin regulates vascular smooth muscle cell nodule formation and migration</title><title level="a" type="short" xml:lang="en">Clusterin Regulates Vascular Muscle Cells</title><author xml:id="author-0000" role="corresp"><persName><forename type="first">Albert J.T.</forename><surname>Millis</surname></persName><email>millis@csc.albany.edu</email><affiliation><orgName type="institution">Center for Comparative Functional Genomics</orgName><orgName type="laboratory">Department of Biological Sciences</orgName><orgName type="institution">University at Albany‐SUNY</orgName><address><addrLine>Albany</addrLine><addrLine>New York</addrLine><country key="US" xml:lang="en">UNITED STATES</country></address></affiliation></author><author xml:id="author-0001"><persName><forename type="first">Michael</forename><surname>Luciani</surname></persName><affiliation><orgName type="institution">Center for Comparative Functional Genomics</orgName><orgName type="laboratory">Department of Biological Sciences</orgName><orgName type="institution">University at Albany‐SUNY</orgName><address><addrLine>Albany</addrLine><addrLine>New York</addrLine><country key="US" xml:lang="en">UNITED STATES</country></address></affiliation></author><author xml:id="author-0002"><persName><forename type="first">Heather M.</forename><surname>McCue</surname></persName><affiliation><orgName type="institution">Center for Comparative Functional Genomics</orgName><orgName type="laboratory">Department of Biological Sciences</orgName><orgName type="institution">University at Albany‐SUNY</orgName><address><addrLine>Albany</addrLine><addrLine>New York</addrLine><country key="US" xml:lang="en">UNITED STATES</country></address></affiliation></author><author xml:id="author-0003"><persName><forename type="first">Mark E.</forename><surname>Rosenberg</surname></persName><affiliation><orgName type="division">Department of Medicine</orgName><orgName type="institution">University of Minnesota</orgName><address><addrLine>Minneapolis</addrLine><addrLine>Minnesota</addrLine><country key="US" xml:lang="en">UNITED STATES</country></address></affiliation></author><author xml:id="author-0004"><persName><forename type="first">Casey L.</forename><surname>Moulson</surname></persName><affiliation><orgName type="institution">Center for Comparative Functional Genomics</orgName><orgName type="laboratory">Department of Biological Sciences</orgName><orgName type="institution">University at Albany‐SUNY</orgName><address><addrLine>Albany</addrLine><addrLine>New York</addrLine><country key="US" xml:lang="en">UNITED STATES</country></address></affiliation><affiliation><orgName type="division">Renal Division</orgName><orgName type="institution">Washington University of St. Louis School of Medicine</orgName><address><addrLine>660 Euclid Avenue</addrLine><addrLine>St. Louis, MO 63110.</addrLine><country key="US" xml:lang="en">UNITED STATES</country></address></affiliation></author><idno type="istex">BB776BE5D099364B5E02D9FCC7DAF7C3CEDE7A85</idno><idno type="ark">ark:/67375/WNG-9DRCK8TN-B</idno><idno type="DOI">10.1002/1097-4652(200102)186:2<210::AID-JCP1019>3.0.CO;2-N</idno><idno type="unit">JCP1019</idno><idno type="toTypesetVersion">file:JCP.JCP1019.pdf</idno></analytic><monogr><title level="j" type="main">Journal of Cellular Physiology</title><title level="j" type="alt">JOURNAL OF CELLULAR PHYSIOLOGY</title><idno type="pISSN">0021-9541</idno><idno type="eISSN">1097-4652</idno><idno type="book-DOI">10.1002/(ISSN)1097-4652</idno><idno type="book-part-DOI">10.1002/1097-4652(200002)186:2<>1.0.CO;2-V</idno><idno type="product">JCP</idno><imprint><biblScope unit="vol">186</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="210">210</biblScope><biblScope unit="page" to="219">219</biblScope><biblScope unit="page-count">10</biblScope><publisher>John Wiley & Sons, Inc.</publisher><pubPlace>New York</pubPlace><date type="published" when="2001-02"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><encodingDesc><schemaRef type="ODD" url="https://xml-schema.delivery.istex.fr/tei-istex.odd"></schemaRef><appInfo><application ident="pub2tei" version="1.0.10" when="2019-12-20"><label>pub2TEI-ISTEX</label><desc>A set of style sheets for converting XML documents encoded in various scientific publisher formats into a common TEI format.
<ref target="http://www.tei-c.org/">We use TEI</ref></desc></application></appInfo></encodingDesc><profileDesc><abstract xml:lang="en" style="main"><head>Abstract</head><p>Vascular smooth muscle cells (VSMC) are the principal cellular component of the blood vessel wall where they exist in a differentiated state to maintain vascular tone. However, VSMC are not terminally differentiated and can be induced to dediffentiate, proliferate, and migrate. In fact, smooth muscle cell migration from the vascular wall into the lumen of the vessel is a central feature of occlusive vascular pathologies including atherosclerosis and intimal hyperplasia. In vitro, in the presence of an extracellular matrix, cultured vascular smooth muscle cells can migrate and invade the underlying gelatinous matrix, form multicellular nodular aggregations, and secrete the glycoprotein clusterin. Nodular cultures appear to mimic some of the properties of differentiated VSMC, in vivo. Here, to test the hypothesis that clusterin functions to modulate the formation of VSMC nodules and to facilitate cell migration a clusterin negative VSMC clone, SM‐CLU13AS (Moulson and Millis, <ref type="bibr" target="#bib28">1999</ref>, J Cell Physiol 180:355), was transiently transfected with plasmid pRcCMVCLU that contains the full‐length porcine clusterin cDNA sequence under control of the CMV promoter. The transiently transfected VSMC culture expressed and secreted clusterin and formed nodules. To determine if clusterin regulates VSMC migration we used modified Boyden chamber assays. Clusterin, at 10 μg/ml, clearly promotes VSMC migration. In addition, a 15 amino acid synthetic peptide, representing amino acids 118–132 [KQTCMKFYARVCRSG] of the mature clusterin polypeptide, inhibits VSMC attachment to gelatinous substrate. Finally, clusterin appears to have a role in regulating endogenous clusterin expression in the clusterin negative clone. These results clearly establish that clusterin has functional role in VSMC nodule formation and support the conclusion that clusterin is a critical component of smooth muscle cell phenotypic modulation. J. Cell. Physiol. 186:210–219, 2001. © 2001 Wiley‐Liss, Inc.</p></abstract><textClass><keywords rend="articleCategory"><term>Original Article</term></keywords><keywords rend="tocHeading1"><term>Original Articles</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc><revisionDesc><change when="2019-12-20" who="#istex" xml:id="pub2tei">formatting</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-9DRCK8TN-B/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>John Wiley & Sons, Inc.</publisherName><publisherLoc>New York</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1097-4652</doi><issn type="print">0021-9541</issn><issn type="electronic">1097-4652</issn><idGroup><id type="product" value="JCP"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="JOURNAL OF CELLULAR PHYSIOLOGY">Journal of Cellular Physiology</title><title type="short">J. Cell. Physiol.</title></titleGroup></publicationMeta><publicationMeta level="part" position="20"><doi origin="wiley" registered="yes">10.1002/1097-4652(200002)186:2<>1.0.CO;2-V</doi><numberingGroup><numbering type="journalVolume" number="186">186</numbering><numbering type="journalIssue">2</numbering></numberingGroup><coverDate startDate="2001-02">February 2001</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="60" status="forIssue"><doi origin="wiley" registered="yes">10.1002/1097-4652(200102)186:2<210::AID-JCP1019>3.0.CO;2-N</doi><idGroup><id type="unit" value="JCP1019"></id></idGroup><countGroup><count type="pageTotal" number="10"></count></countGroup><titleGroup><title type="articleCategory">Original Article</title><title type="tocHeading1">Original Articles</title></titleGroup><copyright ownership="publisher">Copyright © 2001 Wiley‐Liss, Inc.</copyright><eventGroup><event type="manuscriptReceived" date="2000-05-02"></event><event type="manuscriptAccepted" date="2000-08-25"></event><event type="firstOnline" date="2000-12-21"></event><event type="publishedOnlineFinalForm" date="2001-01-11"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:2.4.7 mode:FullText source:FullText result:FullText" date="2011-02-24"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-30"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-24"></event></eventGroup><numberingGroup><numbering type="pageFirst">210</numbering><numbering type="pageLast">219</numbering></numberingGroup><correspondenceTo>Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, 1400 Washington Avenue, Albany, NY 12222.</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:JCP.JCP1019.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="7"></count><count type="tableTotal" number="0"></count><count type="referenceTotal" number="45"></count><count type="wordTotal" number="6483"></count></countGroup><titleGroup><title type="main" xml:lang="en">Clusterin regulates vascular smooth muscle cell nodule formation and migration</title><title type="short" xml:lang="en">Clusterin Regulates Vascular Muscle Cells</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Albert J.T.</givenNames><familyName>Millis</familyName></personName><contactDetails><email>millis@csc.albany.edu</email></contactDetails></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Michael</givenNames><familyName>Luciani</familyName></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Heather M.</givenNames><familyName>McCue</familyName></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Mark E.</givenNames><familyName>Rosenberg</familyName></personName></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af1" currentRef="#curr1"><personName><givenNames>Casey L.</givenNames><familyName>Moulson</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="US" type="organization"><unparsedAffiliation>Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, Albany, New York</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="US" type="organization"><unparsedAffiliation>Department of Medicine, University of Minnesota, Minneapolis, Minnesota</unparsedAffiliation></affiliation><affiliation xml:id="curr1" countryCode="US"><unparsedAffiliation>Renal Division, Washington University of St. Louis School of Medicine, 660 Euclid Avenue, St. Louis, MO 63110.</unparsedAffiliation></affiliation></affiliationGroup><fundingInfo><fundingAgency>National Heart, Lung, and Blood Institute, National Institutes of Health</fundingAgency><fundingNumber>HL: RO1‐40417</fundingNumber></fundingInfo><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>Vascular smooth muscle cells (VSMC) are the principal cellular component of the blood vessel wall where they exist in a differentiated state to maintain vascular tone. However, VSMC are not terminally differentiated and can be induced to dediffentiate, proliferate, and migrate. In fact, smooth muscle cell migration from the vascular wall into the lumen of the vessel is a central feature of occlusive vascular pathologies including atherosclerosis and intimal hyperplasia. In vitro, in the presence of an extracellular matrix, cultured vascular smooth muscle cells can migrate and invade the underlying gelatinous matrix, form multicellular nodular aggregations, and secrete the glycoprotein clusterin. Nodular cultures appear to mimic some of the properties of differentiated VSMC, in vivo. Here, to test the hypothesis that clusterin functions to modulate the formation of VSMC nodules and to facilitate cell migration a clusterin negative VSMC clone, SM‐CLU13AS (Moulson and Millis, <link href="#bib28">1999</link>, J Cell Physiol 180:355), was transiently transfected with plasmid pRcCMVCLU that contains the full‐length porcine clusterin cDNA sequence under control of the CMV promoter. The transiently transfected VSMC culture expressed and secreted clusterin and formed nodules. To determine if clusterin regulates VSMC migration we used modified Boyden chamber assays. Clusterin, at 10 μg/ml, clearly promotes VSMC migration. In addition, a 15 amino acid synthetic peptide, representing amino acids 118–132 [KQTCMKFYARVCRSG] of the mature clusterin polypeptide, inhibits VSMC attachment to gelatinous substrate. Finally, clusterin appears to have a role in regulating endogenous clusterin expression in the clusterin negative clone. These results clearly establish that clusterin has functional role in VSMC nodule formation and support the conclusion that clusterin is a critical component of smooth muscle cell phenotypic modulation. J. Cell. Physiol. 186:210–219, 2001. © 2001 Wiley‐Liss, Inc.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Clusterin regulates vascular smooth muscle cell nodule formation and migration</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Clusterin Regulates Vascular Muscle Cells</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Clusterin regulates vascular smooth muscle cell nodule formation and migration</title></titleInfo><name type="personal"><namePart type="given">Albert J.T.</namePart><namePart type="family">Millis</namePart><affiliation>Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, Albany, New York</affiliation><affiliation>E-mail: millis@csc.albany.edu</affiliation><affiliation>Correspondence address: Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, 1400 Washington Avenue, Albany, NY 12222.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Michael</namePart><namePart type="family">Luciani</namePart><affiliation>Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, Albany, New York</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Heather M.</namePart><namePart type="family">McCue</namePart><affiliation>Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, Albany, New York</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Mark E.</namePart><namePart type="family">Rosenberg</namePart><affiliation>Department of Medicine, University of Minnesota, Minneapolis, Minnesota</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Casey L.</namePart><namePart type="family">Moulson</namePart><affiliation>Center for Comparative Functional Genomics, Department of Biological Sciences, University at Albany‐SUNY, Albany, New York</affiliation><affiliation>Current Address: Renal Division, Washington University of St. Louis School of Medicine, 660 Euclid Avenue, St. Louis, MO 63110.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>John Wiley & Sons, Inc.</publisher><place><placeTerm type="text">New York</placeTerm></place><dateIssued encoding="w3cdtf">2001-02</dateIssued><dateCaptured encoding="w3cdtf">2000-05-02</dateCaptured><dateValid encoding="w3cdtf">2000-08-25</dateValid><copyrightDate encoding="w3cdtf">2001</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="figures">7</extent><extent unit="tables">0</extent><extent unit="references">45</extent><extent unit="words">6483</extent></physicalDescription><abstract lang="en">Vascular smooth muscle cells (VSMC) are the principal cellular component of the blood vessel wall where they exist in a differentiated state to maintain vascular tone. However, VSMC are not terminally differentiated and can be induced to dediffentiate, proliferate, and migrate. In fact, smooth muscle cell migration from the vascular wall into the lumen of the vessel is a central feature of occlusive vascular pathologies including atherosclerosis and intimal hyperplasia. In vitro, in the presence of an extracellular matrix, cultured vascular smooth muscle cells can migrate and invade the underlying gelatinous matrix, form multicellular nodular aggregations, and secrete the glycoprotein clusterin. Nodular cultures appear to mimic some of the properties of differentiated VSMC, in vivo. Here, to test the hypothesis that clusterin functions to modulate the formation of VSMC nodules and to facilitate cell migration a clusterin negative VSMC clone, SM‐CLU13AS (Moulson and Millis, 1999, J Cell Physiol 180:355), was transiently transfected with plasmid pRcCMVCLU that contains the full‐length porcine clusterin cDNA sequence under control of the CMV promoter. The transiently transfected VSMC culture expressed and secreted clusterin and formed nodules. To determine if clusterin regulates VSMC migration we used modified Boyden chamber assays. Clusterin, at 10 μg/ml, clearly promotes VSMC migration. In addition, a 15 amino acid synthetic peptide, representing amino acids 118–132 [KQTCMKFYARVCRSG] of the mature clusterin polypeptide, inhibits VSMC attachment to gelatinous substrate. Finally, clusterin appears to have a role in regulating endogenous clusterin expression in the clusterin negative clone. These results clearly establish that clusterin has functional role in VSMC nodule formation and support the conclusion that clusterin is a critical component of smooth muscle cell phenotypic modulation. J. Cell. Physiol. 186:210–219, 2001. © 2001 Wiley‐Liss, Inc.</abstract><note type="funding">National Heart, Lung, and Blood Institute, National Institutes of Health - No. HL: RO1‐40417; </note><relatedItem type="host"><titleInfo><title>Journal of Cellular Physiology</title></titleInfo><titleInfo type="abbreviated"><title>J. Cell. Physiol.</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><subject><genre>article-category</genre><topic>Original Article</topic><topic>Original Articles</topic></subject><identifier type="ISSN">0021-9541</identifier><identifier type="eISSN">1097-4652</identifier><identifier type="DOI">10.1002/(ISSN)1097-4652</identifier><identifier type="PublisherID">JCP</identifier><part><date>2001</date><detail type="volume"><caption>vol.</caption><number>186</number></detail><detail type="issue"><caption>no.</caption><number>2</number></detail><extent unit="pages"><start>210</start><end>219</end><total>10</total></extent></part></relatedItem><relatedItem type="references" displayLabel="cit1"><titleInfo><title>Apolipoprotein J expression at fluid‐tissue interfaces, potential role in barrier cytoprotection</title></titleInfo><name type="personal"><namePart type="given">BJ</namePart><namePart type="family">Aronow</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SD</namePart><namePart type="family">Lund</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">TL</namePart><namePart type="family">Brown</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JK</namePart><namePart type="family">Harmony</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DP</namePart><namePart type="family">Witte</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Aronow BJ, Lund SD, Brown TL, Harmony JK, Witte DP. 1993. Apolipoprotein J expression at fluid‐tissue interfaces, potential role in barrier cytoprotection. Proc Natl Acad Sci USA 90:725–729.</note><part><date>1993</date><detail type="volume"><caption>vol.</caption><number>90</number></detail><extent unit="pages"><start>725</start><end>729</end></extent></part><relatedItem type="host"><titleInfo><title>Proc Natl Acad Sci USA</title></titleInfo><part><date>1993</date><detail type="volume"><caption>vol.</caption><number>90</number></detail><extent unit="pages"><start>725</start><end>729</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit2"><titleInfo><title>Viruses in the etiology of atherosclerosis</title></titleInfo><name type="personal"><namePart type="given">E</namePart><namePart type="family">Benditt</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Barrettt</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">McDougall</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Benditt E, Barrettt T, McDougall J. 1983. Viruses in the etiology of atherosclerosis. Proc Nat Acad Sci USA 80:6386–6389.</note><part><date>1983</date><detail type="volume"><caption>vol.</caption><number>80</number></detail><extent unit="pages"><start>6386</start><end>6389</end></extent></part><relatedItem type="host"><titleInfo><title>Proc Nat Acad Sci USA</title></titleInfo><part><date>1983</date><detail type="volume"><caption>vol.</caption><number>80</number></detail><extent unit="pages"><start>6386</start><end>6389</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit3"><titleInfo><title>Purification and characterization of a cell‐aggregating factor (clusterin), the major glycoprotein in ram rete testis fluid</title></titleInfo><name type="personal"><namePart type="given">O</namePart><namePart type="family">Blaschuk</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Burdzy</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">IB</namePart><namePart type="family">Fritz</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Blaschuk O, Burdzy K, Fritz IB. 1983. Purification and characterization of a cell‐aggregating factor (clusterin), the major glycoprotein in ram rete testis fluid. J Biol Chem 258:7714–7720.</note><part><date>1983</date><detail type="volume"><caption>vol.</caption><number>258</number></detail><extent unit="pages"><start>7714</start><end>7720</end></extent></part><relatedItem type="host"><titleInfo><title>J Biol Chem</title></titleInfo><part><date>1983</date><detail type="volume"><caption>vol.</caption><number>258</number></detail><extent unit="pages"><start>7714</start><end>7720</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit4"><titleInfo><title>Bone morphogenic protein expression in human atherosclerotic lesions</title></titleInfo><name type="personal"><namePart type="given">K</namePart><namePart type="family">Bostrom</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KE</namePart><namePart type="family">Watson</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Horn</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Wortham</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">IM</namePart><namePart type="family">Herman</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">LL</namePart><namePart type="family">Demer</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Bostrom K, Watson KE, Horn S, Wortham C, Herman IM, Demer LL. 1993. Bone morphogenic protein expression in human atherosclerotic lesions. J Clin Invest 91:1800–1809.</note><part><date>1993</date><detail type="volume"><caption>vol.</caption><number>91</number></detail><extent unit="pages"><start>1800</start><end>1809</end></extent></part><relatedItem type="host"><titleInfo><title>J Clin Invest</title></titleInfo><part><date>1993</date><detail type="volume"><caption>vol.</caption><number>91</number></detail><extent unit="pages"><start>1800</start><end>1809</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit5"><titleInfo><title>Fibronectin inhibits morphological changes in cultures of vascular smooth muscle cells</title></titleInfo><name type="personal"><namePart type="given">MJ</namePart><namePart type="family">Brennan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AJT</namePart><namePart type="family">Millis</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KE</namePart><namePart type="family">Fritz</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Brennan MJ, Millis AJT, Fritz KE. 1982. Fibronectin inhibits morphological changes in cultures of vascular smooth muscle cells. J Cell Physiol 112:284–290.</note><part><date>1982</date><detail type="volume"><caption>vol.</caption><number>112</number></detail><extent unit="pages"><start>284</start><end>290</end></extent></part><relatedItem type="host"><titleInfo><title>J Cell Physiol</title></titleInfo><part><date>1982</date><detail type="volume"><caption>vol.</caption><number>112</number></detail><extent unit="pages"><start>284</start><end>290</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit6"><titleInfo><title>Structural alterations in fibronectin correlated with morphological changes in smooth muscle cells</title></titleInfo><name type="personal"><namePart type="given">MJ</namePart><namePart type="family">Brennan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AJT</namePart><namePart type="family">Millis</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DM</namePart><namePart type="family">Mann</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KE</namePart><namePart type="family">Fritz</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Brennan MJ, Millis AJT, Mann DM, Fritz KE. 1983. Structural alterations in fibronectin correlated with morphological changes in smooth muscle cells. Dev Biol 97:391–397.</note><part><date>1983</date><detail type="volume"><caption>vol.</caption><number>97</number></detail><extent unit="pages"><start>391</start><end>397</end></extent></part><relatedItem type="host"><titleInfo><title>Dev Biol</title></titleInfo><part><date>1983</date><detail type="volume"><caption>vol.</caption><number>97</number></detail><extent unit="pages"><start>391</start><end>397</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit7"><titleInfo><title>Intracellular processing of apolipoprotein J precursor to the mature heterodimer</title></titleInfo><name type="personal"><namePart type="given">BF</namePart><namePart type="family">Burkey</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HV</namePart><namePart type="family">DeSilva</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JA</namePart><namePart type="family">Harmony</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Burkey BF, DeSilva HV, Harmony JA. 1991. Intracellular processing of apolipoprotein J precursor to the mature heterodimer. J Lip Res 32:1039–1048.</note><part><date>1991</date><detail type="volume"><caption>vol.</caption><number>32</number></detail><extent unit="pages"><start>1039</start><end>1048</end></extent></part><relatedItem type="host"><titleInfo><title>J Lip Res</title></titleInfo><part><date>1991</date><detail type="volume"><caption>vol.</caption><number>32</number></detail><extent unit="pages"><start>1039</start><end>1048</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit8"><titleInfo><title>Induction of the TRPM‐2 gene in cells undergoing programmed death</title></titleInfo><name type="personal"><namePart type="given">R</namePart><namePart type="family">Buttyan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">CA</namePart><namePart type="family">Olsson</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Pintar</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Chang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Bandyk</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Po‐Y</namePart><namePart type="family">Ng</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">I</namePart><namePart type="family">Sawczuk</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Buttyan R, Olsson CA, Pintar J, Chang C, Bandyk M, Ng Po‐Y, Sawczuk I. 1989. Induction of the TRPM‐2 gene in cells undergoing programmed death. Mol Cell Biol 9:3473–3481.</note><part><date>1989</date><detail type="volume"><caption>vol.</caption><number>9</number></detail><extent unit="pages"><start>3473</start><end>3481</end></extent></part><relatedItem type="host"><titleInfo><title>Mol Cell Biol</title></titleInfo><part><date>1989</date><detail type="volume"><caption>vol.</caption><number>9</number></detail><extent unit="pages"><start>3473</start><end>3481</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit9"><titleInfo><title>Biosynthesis and molecular cloning of sulfated glycoprotein‐2 secreted by rat Sertoli cells</title></titleInfo><name type="personal"><namePart type="given">MW</namePart><namePart type="family">Collard</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MD</namePart><namePart type="family">Griswold</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Collard MW, Griswold MD. 1987. Biosynthesis and molecular cloning of sulfated glycoprotein‐2 secreted by rat Sertoli cells. Biochemistry 26:3297–3303.</note><part><date>1987</date><detail type="volume"><caption>vol.</caption><number>26</number></detail><extent unit="pages"><start>3297</start><end>3303</end></extent></part><relatedItem type="host"><titleInfo><title>Biochemistry</title></titleInfo><part><date>1987</date><detail type="volume"><caption>vol.</caption><number>26</number></detail><extent unit="pages"><start>3297</start><end>3303</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit10"><titleInfo><title>Angiogenesis: models and modulators</title></titleInfo><name type="personal"><namePart type="given">GW</namePart><namePart type="family">Cockerill</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JR</namePart><namePart type="family">Gamble</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MA</namePart><namePart type="family">Vadas</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Cockerill GW, Gamble JR, Vadas MA. 1995. Angiogenesis: models and modulators. Int Rev Cytol 159:113–160.</note><part><date>1995</date><detail type="volume"><caption>vol.</caption><number>159</number></detail><extent unit="pages"><start>113</start><end>160</end></extent></part><relatedItem type="host"><titleInfo><title>Int Rev Cytol</title></titleInfo><part><date>1995</date><detail type="volume"><caption>vol.</caption><number>159</number></detail><extent unit="pages"><start>113</start><end>160</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit11"><titleInfo><title>Expression of porcine complement cytolysis inhibitor mRNA in cultured aortic smooth muscle cells</title></titleInfo><name type="personal"><namePart type="given">VD</namePart><namePart type="family">Diemer</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Hoyle</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Baglioni</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AJT</namePart><namePart type="family">Millis</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Diemer VD, Hoyle M, Baglioni C, Millis AJT. 1992. Expression of porcine complement cytolysis inhibitor mRNA in cultured aortic smooth muscle cells. J Biol Chem 267:5257–52646.</note><part><date>1992</date><detail type="volume"><caption>vol.</caption><number>267</number></detail><extent unit="pages"><start>5257</start><end>52646</end></extent></part><relatedItem type="host"><titleInfo><title>J Biol Chem</title></titleInfo><part><date>1992</date><detail type="volume"><caption>vol.</caption><number>267</number></detail><extent unit="pages"><start>5257</start><end>52646</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit12"><titleInfo><title>Long‐term neonatal rat aortic smooth muscle cell cultures, a model for the tunica media of a blood vessel</title></titleInfo><name type="personal"><namePart type="given">B</namePart><namePart type="family">Faris</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">OT</namePart><namePart type="family">Tan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Toselli</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Franzblau</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Faris B, Tan OT, Toselli P, Franzblau C. 1992. Long‐term neonatal rat aortic smooth muscle cell cultures, a model for the tunica media of a blood vessel. Matrix 12:185–188.</note><part><date>1992</date><detail type="volume"><caption>vol.</caption><number>12</number></detail><extent unit="pages"><start>185</start><end>188</end></extent></part><relatedItem type="host"><titleInfo><title>Matrix</title></titleInfo><part><date>1992</date><detail type="volume"><caption>vol.</caption><number>12</number></detail><extent unit="pages"><start>185</start><end>188</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit13"><titleInfo><title>Murine clusterin, molecular cloning and mRNA localization of a gene associated with epithelial differentiation process during embryogenesis</title></titleInfo><name type="personal"><namePart type="given">LE</namePart><namePart type="family">French</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Chonn</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Ducrest</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Baumann</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Belin</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Wohlwend</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JZ</namePart><namePart type="family">Kiss</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A‐P</namePart><namePart type="family">Sappino</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Tschopp</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JA</namePart><namePart type="family">Schifferli</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">French LE, Chonn A, Ducrest E, Baumann B, Belin D, Wohlwend A, Kiss JZ, Sappino A‐P, Tschopp J, Schifferli JA. 1993. Murine clusterin, molecular cloning and mRNA localization of a gene associated with epithelial differentiation process during embryogenesis. J Cell Biol 122:119–1130.</note><part><date>1993</date><detail type="volume"><caption>vol.</caption><number>122</number></detail><extent unit="pages"><start>119</start><end>1130</end></extent></part><relatedItem type="host"><titleInfo><title>J Cell Biol</title></titleInfo><part><date>1993</date><detail type="volume"><caption>vol.</caption><number>122</number></detail><extent unit="pages"><start>119</start><end>1130</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit14"><titleInfo><title>Human vascular smooth muscle in culture. Growth and ultrastructure</title></titleInfo><name type="personal"><namePart type="given">MA</namePart><namePart type="family">Gimbrone</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">RS</namePart><namePart type="family">Cotran</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Gimbrone MA, Cotran RS. 1975. Human vascular smooth muscle in culture. Growth and ultrastructure. Lab Invest 33:16–27.</note><part><date>1975</date><detail type="volume"><caption>vol.</caption><number>33</number></detail><extent unit="pages"><start>16</start><end>27</end></extent></part><relatedItem type="host"><titleInfo><title>Lab Invest</title></titleInfo><part><date>1975</date><detail type="volume"><caption>vol.</caption><number>33</number></detail><extent unit="pages"><start>16</start><end>27</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit15"><titleInfo><title>Molecular cloning of gp80, a glycoprotein complex secreted by kidney cells in vitro and in vivo</title></titleInfo><name type="personal"><namePart type="given">K</namePart><namePart type="family">Hartmann</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Rauch</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Urban</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Parczyk</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Diel</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Pilarsky</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Appel</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">W</namePart><namePart type="family">Haase</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Mann</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Weller</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Koch‐Brandt</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Hartmann K, Rauch J, Urban J, Parczyk K, Diel P, Pilarsky C, Appel D, Haase W, Mann K, Weller A, Koch‐Brandt C. 1991. Molecular cloning of gp80, a glycoprotein complex secreted by kidney cells in vitro and in vivo. J Biol Chem 266:9924–9931.</note><part><date>1991</date><detail type="volume"><caption>vol.</caption><number>266</number></detail><extent unit="pages"><start>9924</start><end>9931</end></extent></part><relatedItem type="host"><titleInfo><title>J Biol Chem</title></titleInfo><part><date>1991</date><detail type="volume"><caption>vol.</caption><number>266</number></detail><extent unit="pages"><start>9924</start><end>9931</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit16"><titleInfo><title>Plasma fibronectin modulation of arterial smooth muscle cells from contractile to synthetic phenotype</title></titleInfo><name type="personal"><namePart type="given">U</namePart><namePart type="family">Hedin</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Thyberg</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Hedin U, Thyberg J. 1987. Plasma fibronectin modulation of arterial smooth muscle cells from contractile to synthetic phenotype. Differentiation 33:239–246.</note><part><date>1987</date><detail type="volume"><caption>vol.</caption><number>33</number></detail><extent unit="pages"><start>239</start><end>246</end></extent></part><relatedItem type="host"><titleInfo><title>Differentiation</title></titleInfo><part><date>1987</date><detail type="volume"><caption>vol.</caption><number>33</number></detail><extent unit="pages"><start>239</start><end>246</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit17"><titleInfo><title>Distribution and synthesis of apolipoprotein J in the atherosclerotic aorta</title></titleInfo><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Ishikawa</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Akasaka</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Ishii</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Komiyama</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Masuda</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">N</namePart><namePart type="family">Asuwa</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">NH</namePart><namePart type="family">Choi‐Miura</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Tomita</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Ishikawa Y, Akasaka Y, Ishii T, Komiyama K, Masuda S, Asuwa N, Choi‐Miura NH, Tomita M. 1998. Distribution and synthesis of apolipoprotein J in the atherosclerotic aorta. Arterioscler Thromb Vasc Biol 18:665–672.</note><part><date>1998</date><detail type="volume"><caption>vol.</caption><number>18</number></detail><extent unit="pages"><start>665</start><end>672</end></extent></part><relatedItem type="host"><titleInfo><title>Arterioscler Thromb Vasc Biol</title></titleInfo><part><date>1998</date><detail type="volume"><caption>vol.</caption><number>18</number></detail><extent unit="pages"><start>665</start><end>672</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit18"><titleInfo><title>A peptide inhibiting the collagen binding function of integrin α2I domain</title></titleInfo><name type="personal"><namePart type="given">J</namePart><namePart type="family">Ivaska</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Kapyla</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">O</namePart><namePart type="family">Pentikainen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A‐M</namePart><namePart type="family">Hoffren</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Hermonen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P</namePart><namePart type="family">Huttunen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MS</namePart><namePart type="family">Johnson</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Heino</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Ivaska J, Kapyla J, Pentikainen O, Hoffren A‐M, Hermonen J, Huttunen P, Johnson MS, Heino J. 1999. A peptide inhibiting the collagen binding function of integrin α2I domain. J Biol Chem 274:3513–3521.</note><part><date>1999</date><detail type="volume"><caption>vol.</caption><number>274</number></detail><extent unit="pages"><start>3513</start><end>3521</end></extent></part><relatedItem type="host"><titleInfo><title>J Biol Chem</title></titleInfo><part><date>1999</date><detail type="volume"><caption>vol.</caption><number>274</number></detail><extent unit="pages"><start>3513</start><end>3521</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit19"><titleInfo><title>Clusterin: the intriguing guises of a widely expressed glycoprotein</title></titleInfo><name type="personal"><namePart type="given">DE</namePart><namePart type="family">Jenne</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Tschopp</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Jenne DE, Tschopp J. 1992. Clusterin: the intriguing guises of a widely expressed glycoprotein. TIBS 17:154–159.</note><part><date>1992</date><detail type="volume"><caption>vol.</caption><number>17</number></detail><extent unit="pages"><start>154</start><end>159</end></extent></part><relatedItem type="host"><titleInfo><title>TIBS</title></titleInfo><part><date>1992</date><detail type="volume"><caption>vol.</caption><number>17</number></detail><extent unit="pages"><start>154</start><end>159</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit20"><titleInfo><title>Identification of glycoprotein 330 as an endocytotic receptor for apolipoprotein J/clusterin</title></titleInfo><name type="personal"><namePart type="given">MZ</namePart><namePart type="family">Kounnas</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">EB</namePart><namePart type="family">Loukinova</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Stefansson</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JAK</namePart><namePart type="family">Harmony</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">BH</namePart><namePart type="family">Brewer</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DK</namePart><namePart type="family">Strickland</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">WS</namePart><namePart type="family">Argraves</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Kounnas MZ, Loukinova EB, Stefansson S, Harmony JAK, Brewer BH, Strickland DK, Argraves WS. 1995. Identification of glycoprotein 330 as an endocytotic receptor for apolipoprotein J/clusterin. J Biol Chem 270:13070–1307.</note><part><date>1995</date><detail type="volume"><caption>vol.</caption><number>270</number></detail><extent unit="pages"><start>13070</start><end>1307</end></extent></part><relatedItem type="host"><titleInfo><title>J Biol Chem</title></titleInfo><part><date>1995</date><detail type="volume"><caption>vol.</caption><number>270</number></detail><extent unit="pages"><start>13070</start><end>1307</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit21"><titleInfo><title>Programmed cell death during regression of PC‐82 human prostate cancer following androgen ablation</title></titleInfo><name type="personal"><namePart type="given">N</namePart><namePart type="family">Kyprianou</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HF</namePart><namePart type="family">English</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JT</namePart><namePart type="family">Isaacs</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Kyprianou N, English HF, Isaacs JT. 1990. Programmed cell death during regression of PC‐82 human prostate cancer following androgen ablation. Biol Reprod 33:177–186.</note><part><date>1990</date><detail type="volume"><caption>vol.</caption><number>33</number></detail><extent unit="pages"><start>177</start><end>186</end></extent></part><relatedItem type="host"><titleInfo><title>Biol Reprod</title></titleInfo><part><date>1990</date><detail type="volume"><caption>vol.</caption><number>33</number></detail><extent unit="pages"><start>177</start><end>186</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit22"><titleInfo><title>Integrin‐mediated collagen matrix reorganization by cultured human vascular smooth muscle cells</title></titleInfo><name type="personal"><namePart type="given">RT</namePart><namePart type="family">Lee</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">F</namePart><namePart type="family">Berditcheveski</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">GC</namePart><namePart type="family">Cheng</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">ME</namePart><namePart type="family">Hemler</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Lee RT, Berditcheveski F, Cheng GC, Hemler ME. 1995. Integrin‐mediated collagen matrix reorganization by cultured human vascular smooth muscle cells. Circ Res 76:209–214.</note><part><date>1995</date><detail type="volume"><caption>vol.</caption><number>76</number></detail><extent unit="pages"><start>209</start><end>214</end></extent></part><relatedItem type="host"><titleInfo><title>Circ Res</title></titleInfo><part><date>1995</date><detail type="volume"><caption>vol.</caption><number>76</number></detail><extent unit="pages"><start>209</start><end>214</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit23"><titleInfo><title>Increased immunolocalization of paraoxonase, clusterin, and apolipoprotein A‐I in the human artery wall with the progression of atherosclerosis</title></titleInfo><name type="personal"><namePart type="given">B</namePart><namePart type="family">Mackness</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Hunt</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">PN</namePart><namePart type="family">Durrington</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MI</namePart><namePart type="family">Mackness</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Mackness B, Hunt R, Durrington PN, Mackness MI. 1997. Increased immunolocalization of paraoxonase, clusterin, and apolipoprotein A‐I in the human artery wall with the progression of atherosclerosis. Arterioscler Thromb Vasc Biol 17:1233–1238.</note><part><date>1997</date><detail type="volume"><caption>vol.</caption><number>17</number></detail><extent unit="pages"><start>1233</start><end>1238</end></extent></part><relatedItem type="host"><titleInfo><title>Arterioscler Thromb Vasc Biol</title></titleInfo><part><date>1997</date><detail type="volume"><caption>vol.</caption><number>17</number></detail><extent unit="pages"><start>1233</start><end>1238</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit24"><titleInfo><title>Multiple involvement of clusterin in chicken ovarian follicle development. Binding to two oocyte‐specific members of the low‐density lipoprotein gene family</title></titleInfo><name type="personal"><namePart type="given">MG</namePart><namePart type="family">Mahon</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KA</namePart><namePart type="family">Lindstedt</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Hermann</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Nimpf</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">WJ</namePart><namePart type="family">Schneider</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Mahon MG, Lindstedt KA, Hermann M, Nimpf J, Schneider WJ. 1999. Multiple involvement of clusterin in chicken ovarian follicle development. Binding to two oocyte‐specific members of the low‐density lipoprotein gene family. J Biol Chem 274:4036–4044.</note><part><date>1999</date><detail type="volume"><caption>vol.</caption><number>274</number></detail><extent unit="pages"><start>4036</start><end>4044</end></extent></part><relatedItem type="host"><titleInfo><title>J Biol Chem</title></titleInfo><part><date>1999</date><detail type="volume"><caption>vol.</caption><number>274</number></detail><extent unit="pages"><start>4036</start><end>4044</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit25"><titleInfo><title>Gp38k, a protein synthesized by vascular smooth muscle cells, stimulates directional migration of human umbilical vein endothelial cells</title></titleInfo><name type="personal"><namePart type="given">KM</namePart><namePart type="family">Malinda</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Ponce</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HK</namePart><namePart type="family">Kleinman</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">LM</namePart><namePart type="family">Shackelton</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AJT</namePart><namePart type="family">Millis</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Malinda KM, Ponce L, Kleinman HK, Shackelton LM, Millis AJT. 1999. Gp38k, a protein synthesized by vascular smooth muscle cells, stimulates directional migration of human umbilical vein endothelial cells. Exp Cell Res 250:168–173.</note><part><date>1999</date><detail type="volume"><caption>vol.</caption><number>250</number></detail><extent unit="pages"><start>168</start><end>173</end></extent></part><relatedItem type="host"><titleInfo><title>Exp Cell Res</title></titleInfo><part><date>1999</date><detail type="volume"><caption>vol.</caption><number>250</number></detail><extent unit="pages"><start>168</start><end>173</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit26"><titleInfo><title>Differential effects of hepatocyte growth factor isoforms on epithelial and endothelial tubulogenesis</title></titleInfo><name type="personal"><namePart type="given">R</namePart><namePart type="family">Montesano</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JV</namePart><namePart type="family">Soriano</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KM</namePart><namePart type="family">Malinda</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">ML</namePart><namePart type="family">Ponce</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Bafico</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HK</namePart><namePart type="family">Kleinman</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DP</namePart><namePart type="family">Bottaro</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SA</namePart><namePart type="family">Aaronson</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Montesano R, Soriano JV, Malinda KM, Ponce ML, Bafico A, Kleinman HK, Bottaro DP, Aaronson SA. 1998. Differential effects of hepatocyte growth factor isoforms on epithelial and endothelial tubulogenesis. Cell Growth Differ 9:355–365.</note><part><date>1998</date><detail type="volume"><caption>vol.</caption><number>9</number></detail><extent unit="pages"><start>355</start><end>365</end></extent></part><relatedItem type="host"><titleInfo><title>Cell Growth Differ</title></titleInfo><part><date>1998</date><detail type="volume"><caption>vol.</caption><number>9</number></detail><extent unit="pages"><start>355</start><end>365</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit27"><titleInfo><title>Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three‐dimensional dermal collagen</title></titleInfo><name type="personal"><namePart type="given">AM</namePart><namePart type="family">Montgomery</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">RA</namePart><namePart type="family">Reisfeld</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DA</namePart><namePart type="family">Cherish</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Montgomery AM, Reisfeld RA, Cherish DA. 1994. Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three‐dimensional dermal collagen. Proc Natl Acad Sci USA 1:8856–8860.</note><part><date>1994</date><detail type="volume"><caption>vol.</caption><number>1</number></detail><extent unit="pages"><start>8856</start><end>8860</end></extent></part><relatedItem type="host"><titleInfo><title>Proc Natl Acad Sci USA</title></titleInfo><part><date>1994</date><detail type="volume"><caption>vol.</caption><number>1</number></detail><extent unit="pages"><start>8856</start><end>8860</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit28"><titleInfo><title>Clusterin (ApoJ) regulates vascular smooth muscle cell differentiation, in vitro</title></titleInfo><name type="personal"><namePart type="given">CL</namePart><namePart type="family">Moulson</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Millis</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Moulson CL, Millis A. 1999. Clusterin (ApoJ) regulates vascular smooth muscle cell differentiation, in vitro. J Cell Physiol 180:355–364.</note><part><date>1999</date><detail type="volume"><caption>vol.</caption><number>180</number></detail><extent unit="pages"><start>355</start><end>364</end></extent></part><relatedItem type="host"><titleInfo><title>J Cell Physiol</title></titleInfo><part><date>1999</date><detail type="volume"><caption>vol.</caption><number>180</number></detail><extent unit="pages"><start>355</start><end>364</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit29"><titleInfo><title>SP‐40, 40, a newly identified normal human serum protein found in the SC5b‐9 complex of complement and in the immune deposits in glomerulonephritis</title></titleInfo><name type="personal"><namePart type="given">BF</namePart><namePart type="family">Murphy</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Kirszbaum</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">ID</namePart><namePart type="family">Walker</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AJF</namePart><namePart type="family">d'Apice</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Murphy BF, Kirszbaum L, Walker ID, d'Apice AJF. 1988. SP‐40, 40, a newly identified normal human serum protein found in the SC5b‐9 complex of complement and in the immune deposits in glomerulonephritis. J Clin Invest 81:1858–1864.</note><part><date>1988</date><detail type="volume"><caption>vol.</caption><number>81</number></detail><extent unit="pages"><start>1858</start><end>1864</end></extent></part><relatedItem type="host"><titleInfo><title>J Clin Invest</title></titleInfo><part><date>1988</date><detail type="volume"><caption>vol.</caption><number>81</number></detail><extent unit="pages"><start>1858</start><end>1864</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit30"><titleInfo><title>Regulation of differentiation of vascular smooth muscle cells</title></titleInfo><name type="personal"><namePart type="given">GK</namePart><namePart type="family">Owens</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Owens GK. 1995. Regulation of differentiation of vascular smooth muscle cells. Physiol Rev 75:487–517.</note><part><date>1995</date><detail type="volume"><caption>vol.</caption><number>75</number></detail><extent unit="pages"><start>487</start><end>517</end></extent></part><relatedItem type="host"><titleInfo><title>Physiol Rev</title></titleInfo><part><date>1995</date><detail type="volume"><caption>vol.</caption><number>75</number></detail><extent unit="pages"><start>487</start><end>517</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit31"><titleInfo><title>Experimental models that mimic the differentiation and dedifferentiation of vascular cells</title></titleInfo><name type="personal"><namePart type="given">RR</namePart><namePart type="family">Pauly</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Passaniti</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Crow</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JL</namePart><namePart type="family">Kinsella</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">N</namePart><namePart type="family">Papadopoulous</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Monticone</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">EG</namePart><namePart type="family">Lakatta</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">GR</namePart><namePart type="family">Martin</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Pauly RR, Passaniti A, Crow M, Kinsella JL, Papadopoulous N, Monticone R, Lakatta EG, Martin GR. 1992. Experimental models that mimic the differentiation and dedifferentiation of vascular cells. Circulation 86(Suppl III):68–73.</note><part><date>1992</date><detail type="volume"><caption>vol.</caption><number>86</number></detail><detail type="issue"><caption>no.</caption><number>Suppl III</number></detail><extent unit="pages"><start>68</start><end>73</end></extent></part><relatedItem type="host"><titleInfo><title>Circulation</title></titleInfo><part><date>1992</date><detail type="volume"><caption>vol.</caption><number>86</number></detail><detail type="issue"><caption>no.</caption><number>Suppl III</number></detail><extent unit="pages"><start>68</start><end>73</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit32"><titleInfo><title>The pathogenesis of atherosclerosis: a perspective for the 1990's</title></titleInfo><name type="personal"><namePart type="given">R</namePart><namePart type="family">Ross</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Ross R. 1993. The pathogenesis of atherosclerosis: a perspective for the 1990's. Nature 362:801–809.</note><part><date>1993</date><detail type="volume"><caption>vol.</caption><number>362</number></detail><extent unit="pages"><start>801</start><end>809</end></extent></part><relatedItem type="host"><titleInfo><title>Nature</title></titleInfo><part><date>1993</date><detail type="volume"><caption>vol.</caption><number>362</number></detail><extent unit="pages"><start>801</start><end>809</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit33"><titleInfo><title>Growth control and morphogenesis in the development and pathology of arteries</title></titleInfo><name type="personal"><namePart type="given">SM</namePart><namePart type="family">Schwartz</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Liaw</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Schwartz SM, Liaw L. 1993. Growth control and morphogenesis in the development and pathology of arteries. Cardiovascular Pharmacol 21:S31–S49.</note><part><date>1993</date><detail type="volume"><caption>vol.</caption><number>21</number></detail><extent unit="pages"><start>S31</start><end>S49</end></extent></part><relatedItem type="host"><titleInfo><title>Cardiovascular Pharmacol</title></titleInfo><part><date>1993</date><detail type="volume"><caption>vol.</caption><number>21</number></detail><extent unit="pages"><start>S31</start><end>S49</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit34"><titleInfo><title>Identification of a 38 kDa heparin binding glycoprotein in differentiating vascular smooth muscle cells as a member of a group of proteins associated with tissue remodeling</title></titleInfo><name type="personal"><namePart type="given">LM</namePart><namePart type="family">Shackelton</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DH</namePart><namePart type="family">Mann</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AJT</namePart><namePart type="family">Millis</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Shackelton LM, Mann DH, Millis AJT. 1995. Identification of a 38 kDa heparin binding glycoprotein in differentiating vascular smooth muscle cells as a member of a group of proteins associated with tissue remodeling. J Biol Chem 270:13076–13083.</note><part><date>1995</date><detail type="volume"><caption>vol.</caption><number>270</number></detail><extent unit="pages"><start>13076</start><end>13083</end></extent></part><relatedItem type="host"><titleInfo><title>J Biol Chem</title></titleInfo><part><date>1995</date><detail type="volume"><caption>vol.</caption><number>270</number></detail><extent unit="pages"><start>13076</start><end>13083</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit35"><titleInfo><title>Isolation of gene markers of differentiated and proliferating vascular smooth muscle cells</title></titleInfo><name type="personal"><namePart type="given">CM</namePart><namePart type="family">Shanahan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">PL</namePart><namePart type="family">Weissberg</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JC</namePart><namePart type="family">Metcalfe</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Shanahan CM, Weissberg PL, Metcalfe JC. 1993. Isolation of gene markers of differentiated and proliferating vascular smooth muscle cells. Circ Res 73:193–204.</note><part><date>1993</date><detail type="volume"><caption>vol.</caption><number>73</number></detail><extent unit="pages"><start>193</start><end>204</end></extent></part><relatedItem type="host"><titleInfo><title>Circ Res</title></titleInfo><part><date>1993</date><detail type="volume"><caption>vol.</caption><number>73</number></detail><extent unit="pages"><start>193</start><end>204</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit36"><titleInfo><title>Clusterin promotes the aggregation and adhesion of renal porcine epithelial cells</title></titleInfo><name type="personal"><namePart type="given">JR</namePart><namePart type="family">Silkensen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KM</namePart><namePart type="family">Skubitz</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">APN</namePart><namePart type="family">Skubitz</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DH</namePart><namePart type="family">Chmlelewski</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JC</namePart><namePart type="family">Manivel</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JA</namePart><namePart type="family">Dvergsten</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">ME</namePart><namePart type="family">Rosenberg</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Silkensen JR, Skubitz KM, Skubitz APN, Chmlelewski DH, Manivel JC, Dvergsten JA, Rosenberg ME. 1995. Clusterin promotes the aggregation and adhesion of renal porcine epithelial cells. J Clin Invest 96:2646–2653.</note><part><date>1995</date><detail type="volume"><caption>vol.</caption><number>96</number></detail><extent unit="pages"><start>2646</start><end>2653</end></extent></part><relatedItem type="host"><titleInfo><title>J Clin Invest</title></titleInfo><part><date>1995</date><detail type="volume"><caption>vol.</caption><number>96</number></detail><extent unit="pages"><start>2646</start><end>2653</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit37"><titleInfo><title>Identification of clusterin sequences mediating renal tubular cell interactions</title></titleInfo><name type="personal"><namePart type="given">JR</namePart><namePart type="family">Silkensen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AP</namePart><namePart type="family">Skubitz</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KM</namePart><namePart type="family">Skubitz</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">ME</namePart><namePart type="family">Rosenberg</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Silkensen JR, Skubitz AP, Skubitz KM, Rosenberg ME. 1999. Identification of clusterin sequences mediating renal tubular cell interactions. J Pept Res 54:449–457.</note><part><date>1999</date><detail type="volume"><caption>vol.</caption><number>54</number></detail><extent unit="pages"><start>449</start><end>457</end></extent></part><relatedItem type="host"><titleInfo><title>J Pept Res</title></titleInfo><part><date>1999</date><detail type="volume"><caption>vol.</caption><number>54</number></detail><extent unit="pages"><start>449</start><end>457</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit38"><titleInfo><title>Dynamic expression of α1β1 and α2β1 integrin receptors by human vascular smooth muscle cells. α1β1 integrin is required for chemotaxis across type I collagen‐coated membranes</title></titleInfo><name type="personal"><namePart type="given">MP</namePart><namePart type="family">Skinner</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">EW</namePart><namePart type="family">Raines</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Ross</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Skinner MP, Raines EW, Ross R. 1994. Dynamic expression of α1β1 and α2β1 integrin receptors by human vascular smooth muscle cells. α1β1 integrin is required for chemotaxis across type I collagen‐coated membranes. Am J Pathol 145:1070–1081.</note><part><date>1994</date><detail type="volume"><caption>vol.</caption><number>145</number></detail><extent unit="pages"><start>1070</start><end>1081</end></extent></part><relatedItem type="host"><titleInfo><title>Am J Pathol</title></titleInfo><part><date>1994</date><detail type="volume"><caption>vol.</caption><number>145</number></detail><extent unit="pages"><start>1070</start><end>1081</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit39"><titleInfo><title>Clusterin expression in differentiating smooth muscle cells</title></titleInfo><name type="personal"><namePart type="given">SA</namePart><namePart type="family">Thomas‐Salgar</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AJT</namePart><namePart type="family">Millis</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Thomas‐Salgar SA, Millis AJT. 1994. Clusterin expression in differentiating smooth muscle cells. J Biol Chem 269:17879–17885.</note><part><date>1994</date><detail type="volume"><caption>vol.</caption><number>269</number></detail><extent unit="pages"><start>17879</start><end>17885</end></extent></part><relatedItem type="host"><titleInfo><title>J Biol Chem</title></titleInfo><part><date>1994</date><detail type="volume"><caption>vol.</caption><number>269</number></detail><extent unit="pages"><start>17879</start><end>17885</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit40"><titleInfo><title>Regulation of differentiated properties and proliferation of arterial smooth muscle cells</title></titleInfo><name type="personal"><namePart type="given">J</namePart><namePart type="family">Thyberg</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">U</namePart><namePart type="family">Hedin</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Sjoplund</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Palmberg</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">BA</namePart><namePart type="family">Bottger</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Thyberg J, Hedin U, Sjoplund M, Palmberg L, Bottger BA. 1990. Regulation of differentiated properties and proliferation of arterial smooth muscle cells. Atherosclerosis 10:966–990.</note><part><date>1990</date><detail type="volume"><caption>vol.</caption><number>10</number></detail><extent unit="pages"><start>966</start><end>990</end></extent></part><relatedItem type="host"><titleInfo><title>Atherosclerosis</title></titleInfo><part><date>1990</date><detail type="volume"><caption>vol.</caption><number>10</number></detail><extent unit="pages"><start>966</start><end>990</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit41"><titleInfo><title>Competition between cell‐substrate and cell‐cell interactions</title></titleInfo><name type="personal"><namePart type="given">PS</namePart><namePart type="family">Tung</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Burdzy</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Wong</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">IB</namePart><namePart type="family">Fritz</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Tung PS, Burdzy K, Wong K, Fritz IB. 1992. Competition between cell‐substrate and cell‐cell interactions. J Cell Physiol 152:410–421.</note><part><date>1992</date><detail type="volume"><caption>vol.</caption><number>152</number></detail><extent unit="pages"><start>410</start><end>421</end></extent></part><relatedItem type="host"><titleInfo><title>J Cell Physiol</title></titleInfo><part><date>1992</date><detail type="volume"><caption>vol.</caption><number>152</number></detail><extent unit="pages"><start>410</start><end>421</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit42"><titleInfo><title>TGFβ1 and 25‐hydroxycholesterol stimulate osteoblast‐like vascular cells to calcify</title></titleInfo><name type="personal"><namePart type="given">KE</namePart><namePart type="family">Watson</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Bostrom</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Ravindranath</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Lam</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Norton</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">LL</namePart><namePart type="family">Demer</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Watson KE, Bostrom K, Ravindranath R, Lam T, Norton B, Demer LL. 1994. TGFβ1 and 25‐hydroxycholesterol stimulate osteoblast‐like vascular cells to calcify. J Clin Invest 93:2106–2113.</note><part><date>1994</date><detail type="volume"><caption>vol.</caption><number>93</number></detail><extent unit="pages"><start>2106</start><end>2113</end></extent></part><relatedItem type="host"><titleInfo><title>J Clin Invest</title></titleInfo><part><date>1994</date><detail type="volume"><caption>vol.</caption><number>93</number></detail><extent unit="pages"><start>2106</start><end>2113</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit43"><titleInfo><title>Platelet aggregation releases megakaryocyte synthesized apolipoprotein J, a highly abundant protein in atheromatous lesions</title></titleInfo><name type="personal"><namePart type="given">DP</namePart><namePart type="family">Witte</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">BJ</namePart><namePart type="family">Aronow</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">ML</namePart><namePart type="family">Stauderman</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">WD</namePart><namePart type="family">Stuart</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MA</namePart><namePart type="family">Clay</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">RA</namePart><namePart type="family">Gruppo</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SH</namePart><namePart type="family">Jenkins</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JAK</namePart><namePart type="family">Harmony</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Witte DP, Aronow BJ, Stauderman ML, Stuart WD, Clay MA, Gruppo RA, Jenkins SH, Harmony JAK. 1993. Platelet aggregation releases megakaryocyte synthesized apolipoprotein J, a highly abundant protein in atheromatous lesions. Am J Pathol 143:763–773.</note><part><date>1993</date><detail type="volume"><caption>vol.</caption><number>143</number></detail><extent unit="pages"><start>763</start><end>773</end></extent></part><relatedItem type="host"><titleInfo><title>Am J Pathol</title></titleInfo><part><date>1993</date><detail type="volume"><caption>vol.</caption><number>143</number></detail><extent unit="pages"><start>763</start><end>773</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit44"><titleInfo><title>Genomic organization and expression of the rat TRPM‐2 (clusterin) gene, a gene implicated in apoptosis</title></titleInfo><name type="personal"><namePart type="given">P</namePart><namePart type="family">Wong</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Pineault</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Lakins</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Taillefer</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Leger</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Tenniswood</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Wong P, Pineault J, Lakins J, Taillefer D, Leger J, Wang C, Tenniswood M. 1993. Genomic organization and expression of the rat TRPM‐2 (clusterin) gene, a gene implicated in apoptosis. J Biol Chem 268:5021–5031.</note><part><date>1993</date><detail type="volume"><caption>vol.</caption><number>268</number></detail><extent unit="pages"><start>5021</start><end>5031</end></extent></part><relatedItem type="host"><titleInfo><title>J Biol Chem</title></titleInfo><part><date>1993</date><detail type="volume"><caption>vol.</caption><number>268</number></detail><extent unit="pages"><start>5021</start><end>5031</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit45"><titleInfo><title>Cell adhesion receptors for native and denatured type I collagens and fibronectin in rabbit arterial smooth muscle cells in culture</title></titleInfo><name type="personal"><namePart type="given">K</namePart><namePart type="family">Yamamoto</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Yamamoto</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Yamamoto K, Yamamoto M. 1994. Cell adhesion receptors for native and denatured type I collagens and fibronectin in rabbit arterial smooth muscle cells in culture. Exp Cell Res 214:258–263.</note><part><date>1994</date><detail type="volume"><caption>vol.</caption><number>214</number></detail><extent unit="pages"><start>258</start><end>263</end></extent></part><relatedItem type="host"><titleInfo><title>Exp Cell Res</title></titleInfo><part><date>1994</date><detail type="volume"><caption>vol.</caption><number>214</number></detail><extent unit="pages"><start>258</start><end>263</end></extent></part></relatedItem></relatedItem><identifier type="istex">BB776BE5D099364B5E02D9FCC7DAF7C3CEDE7A85</identifier><identifier type="ark">ark:/67375/WNG-9DRCK8TN-B</identifier><identifier type="DOI">10.1002/1097-4652(200102)186:2<210::AID-JCP1019>3.0.CO;2-N</identifier><identifier type="ArticleID">JCP1019</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2001 Wiley‐Liss, Inc.</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-L0C46X92-X">wiley</recordContentSource><recordOrigin>Converted from (version ) to MODS version 3.6.</recordOrigin><recordCreationDate encoding="w3cdtf">2019-11-15</recordCreationDate></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-9DRCK8TN-B/record.json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001C03 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 001C03 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:BB776BE5D099364B5E02D9FCC7DAF7C3CEDE7A85
|texte= Clusterin regulates vascular smooth muscle cell nodule formation and migration
}}
| This area was generated with Dilib version V0.6.33. |  |