Uterine expression of sodium/potassium/calcium exchanger 3 and its regulation by sex‐steroid hormones during the estrous cycle of rats
Identifieur interne : 001479 ( Istex/Corpus ); précédent : 001478; suivant : 001480Uterine expression of sodium/potassium/calcium exchanger 3 and its regulation by sex‐steroid hormones during the estrous cycle of rats
Auteurs : Hyun Yang ; Yeong-Min Yoo ; Eui-Man Jung ; Kyung-Chul Choi ; Eui-Bae JeungSource :
- Molecular Reproduction and Development [ 1040-452X ] ; 2010-11.
English descriptors
- Teeft :
- Body weight, Calcium ions, Diestrus, Dong, Embryo, Embryo implantation, Estrogen, Estrous, Estrous cycle, Estrus, Estrus cycle, Exchanger, Expression patterns, Female rats, Glandular epithelium, Immature rats, Implantation, Jeung, Krisinger, Mrna, Nckx3, Nckx3 expression, Nckx3 mrna, Nckx3 mrna expression, Nckx3 protein, Negative control, Proestrus, Progesterone, Rat, Reprod, Salamonsen, Santa cruz, Smooth muscle, Steroid, Steroid hormones, Subcutaneous injection, Trpv6, Uterine, Uterine expression, Uterine expressions, Uterine function, Uterine nckx3, Uterine nckx3 mrna, Uterus.
Abstract
Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. NCKX3 (gene SLC24A3), a potassium‐dependent sodium‐/calcium exchanger, plays a critical role in the transport of one intracellular calcium and potassium ion across the cell membrane in exchange for four extracellular sodium ions. NCKX3 transcripts are most abundant in the brain and smooth muscle, but many other tissues, in particular, the uterus, aorta and intestine, also express this gene at lower levels. However, the expression and physiological roles of NCKX3 in the uterus of rats during the estrous cycle are unknown. Thus, we examined the uterine expression of NCKX3 mRNA and protein at different stages of the estrous cycle in mature and immature female rats in the absence or presence of the sex‐steroid hormones estrogen (E2) and progesterone (P4). During the estrous cycle, uterine expression of NCKX3 mRNA and protein was enhanced up to 4.0‐ and 2.5‐fold, respectively, at proestrus compared to during estrus and diestrus. To examine the effect of sex steroids on NCKX3 regulation in the uterus, immature female rats were treated with E2 (40 µg/kg body weight; BW), P4 (4 mg/kg BW), or E2 plus P4 for 3 days. The expression of NCKX3 mRNA and protein was induced by E2, whereas P4 antagonized E2‐induced NCKX3 expression. Subsequent immunohistochemical analysis revealed that uterine NCKX3 protein was abundantly localized in the cytoplasm of luminal and glandular epithelial cells throughout the estrous cycle. Taken together, these results indicate that uterine NCKX3 is abundantly expressed in the uterus and that its expression is regulated by the steroid hormones, E2 and P4. These findings suggest that NCKX3 may be involved in reproductive function during the estrous cycle in female rats. Mol. Reprod. Dev. 77:971–977, 2010. © 2010 Wiley‐Liss, Inc.
Url:
DOI: 10.1002/mrd.21245
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ISTEX:9ACC4BAFBB7AA1E827E1BEA3B05F77C434BD0426Le document en format XML
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NCKX3 (gene SLC24A3), a potassium‐dependent sodium‐/calcium exchanger, plays a critical role in the transport of one intracellular calcium and potassium ion across the cell membrane in exchange for four extracellular sodium ions. NCKX3 transcripts are most abundant in the brain and smooth muscle, but many other tissues, in particular, the uterus, aorta and intestine, also express this gene at lower levels. However, the expression and physiological roles of NCKX3 in the uterus of rats during the estrous cycle are unknown. Thus, we examined the uterine expression of NCKX3 mRNA and protein at different stages of the estrous cycle in mature and immature female rats in the absence or presence of the sex‐steroid hormones estrogen (E2) and progesterone (P4). During the estrous cycle, uterine expression of NCKX3 mRNA and protein was enhanced up to 4.0‐ and 2.5‐fold, respectively, at proestrus compared to during estrus and diestrus. To examine the effect of sex steroids on NCKX3 regulation in the uterus, immature female rats were treated with E2 (40 µg/kg body weight; BW), P4 (4 mg/kg BW), or E2 plus P4 for 3 days. The expression of NCKX3 mRNA and protein was induced by E2, whereas P4 antagonized E2‐induced NCKX3 expression. Subsequent immunohistochemical analysis revealed that uterine NCKX3 protein was abundantly localized in the cytoplasm of luminal and glandular epithelial cells throughout the estrous cycle. Taken together, these results indicate that uterine NCKX3 is abundantly expressed in the uterus and that its expression is regulated by the steroid hormones, E2 and P4. These findings suggest that NCKX3 may be involved in reproductive function during the estrous cycle in female rats. Mol. Reprod. 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NCKX3 (gene SLC24A3), a potassium‐dependent sodium‐/calcium exchanger, plays a critical role in the transport of one intracellular calcium and potassium ion across the cell membrane in exchange for four extracellular sodium ions. NCKX3 transcripts are most abundant in the brain and smooth muscle, but many other tissues, in particular, the uterus, aorta and intestine, also express this gene at lower levels. However, the expression and physiological roles of NCKX3 in the uterus of rats during the estrous cycle are unknown. Thus, we examined the uterine expression of NCKX3 mRNA and protein at different stages of the estrous cycle in mature and immature female rats in the absence or presence of the sex‐steroid hormones estrogen (E2) and progesterone (P4). During the estrous cycle, uterine expression of NCKX3 mRNA and protein was enhanced up to 4.0‐ and 2.5‐fold, respectively, at proestrus compared to during estrus and diestrus. To examine the effect of sex steroids on NCKX3 regulation in the uterus, immature female rats were treated with E2 (40 µg/kg body weight; BW), P4 (4 mg/kg BW), or E2 plus P4 for 3 days. The expression of NCKX3 mRNA and protein was induced by E2, whereas P4 antagonized E2‐induced NCKX3 expression. Subsequent immunohistochemical analysis revealed that uterine NCKX3 protein was abundantly localized in the cytoplasm of luminal and glandular epithelial cells throughout the estrous cycle. Taken together, these results indicate that uterine NCKX3 is abundantly expressed in the uterus and that its expression is regulated by the steroid hormones, E2 and P4. These findings suggest that NCKX3 may be involved in reproductive function during the estrous cycle in female rats. Mol. Reprod. 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2004a,b</json:string><json:string>Floyd and Wray, 2007</json:string><json:string>Darwish et al., 1991</json:string><json:string>Das et al., 1994</json:string><json:string>Kono et al., 1996</json:string><json:string>An et al., 2003</json:string><json:string>Sanborn, 2000</json:string><json:string>Kim et al., 2006</json:string><json:string>Leach et al., 1993</json:string><json:string>Hong et al., 2004</json:string><json:string>Tatsumi et al., 1999</json:string></ref_bibl><bibl></bibl></unitex></namedEntities><ark><json:string>ark:/67375/WNG-PVSCBZ5C-X</json:string></ark><categories><wos><json:string>1 - science</json:string><json:string>2 - reproductive biology</json:string><json:string>2 - developmental biology</json:string><json:string>2 - cell biology</json:string><json:string>2 - biochemistry & molecular biology</json:string></wos><scienceMetrix><json:string>1 - health sciences</json:string><json:string>2 - clinical medicine</json:string><json:string>3 - obstetrics & reproductive 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type="first">Hyun</forename><surname>Yang</surname></persName><affiliation><orgName type="laboratory">Laboratory of Veterinary Biochemistry and Molecular Biology</orgName><orgName type="institution">College of Veterinary Medicine</orgName><orgName type="institution">Chungbuk National University</orgName><address><addrLine>Cheongju</addrLine><addrLine>Chungbuk, Republic of Korea</addrLine><country key="KR" xml:lang="en">KOREA, REPUBLIC OF</country></address></affiliation></author><author xml:id="author-0001"><persName><forename type="first">Yeong‐Min</forename><surname>Yoo</surname></persName><affiliation><orgName type="laboratory">Laboratory of Veterinary Biochemistry and Molecular Biology</orgName><orgName type="institution">College of Veterinary Medicine</orgName><orgName type="institution">Chungbuk National University</orgName><address><addrLine>Cheongju</addrLine><addrLine>Chungbuk, Republic of Korea</addrLine><country key="KR" xml:lang="en">KOREA, REPUBLIC OF</country></address></affiliation></author><author xml:id="author-0002"><persName><forename type="first">Eui‐Man</forename><surname>Jung</surname></persName><affiliation><orgName type="laboratory">Laboratory of Veterinary Biochemistry and Molecular Biology</orgName><orgName type="institution">College of Veterinary Medicine</orgName><orgName type="institution">Chungbuk National University</orgName><address><addrLine>Cheongju</addrLine><addrLine>Chungbuk, Republic of Korea</addrLine><country key="KR" xml:lang="en">KOREA, REPUBLIC OF</country></address></affiliation></author><author xml:id="author-0003"><persName><forename type="first">Kyung‐Chul</forename><surname>Choi</surname></persName><affiliation><orgName type="laboratory">Laboratory of Veterinary Biochemistry and Molecular Biology</orgName><orgName type="institution">College of Veterinary Medicine</orgName><orgName type="institution">Chungbuk National University</orgName><address><addrLine>Cheongju</addrLine><addrLine>Chungbuk, Republic of Korea</addrLine><country key="KR" xml:lang="en">KOREA, REPUBLIC OF</country></address></affiliation></author><author xml:id="author-0004" role="corresp"><persName><forename type="first">Eui‐Bae</forename><surname>Jeung</surname></persName><email>ebjeung@chungbuk.ac.kr</email><affiliation><orgName type="laboratory">Laboratory of Veterinary Biochemistry and Molecular Biology</orgName><orgName type="institution">College of Veterinary Medicine</orgName><orgName type="institution">Chungbuk National University</orgName><address><addrLine>Cheongju</addrLine><addrLine>Chungbuk, Republic of Korea</addrLine><country key="KR" xml:lang="en">KOREA, REPUBLIC OF</country></address></affiliation></author><idno type="istex">9ACC4BAFBB7AA1E827E1BEA3B05F77C434BD0426</idno><idno type="ark">ark:/67375/WNG-PVSCBZ5C-X</idno><idno type="DOI">10.1002/mrd.21245</idno><idno type="unit">MRD21245</idno><idno type="toTypesetVersion">file:MRD.MRD21245.pdf</idno></analytic><monogr><title level="j" type="main">Molecular Reproduction and Development</title><title level="j" type="alt">MOLECULAR REPRODUCTION AND DEVELOPMENT</title><idno type="pISSN">1040-452X</idno><idno type="eISSN">1098-2795</idno><idno type="book-DOI">10.1002/(ISSN)1098-2795</idno><idno type="book-part-DOI">10.1002/mrd.v77:11</idno><idno type="product">MRD</idno><imprint><biblScope unit="vol">77</biblScope><biblScope unit="issue">11</biblScope><biblScope unit="page" from="971">971</biblScope><biblScope unit="page" to="977">977</biblScope><biblScope unit="page-count">7</biblScope><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2010-11"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><encodingDesc><schemaRef type="ODD" url="https://xml-schema.delivery.istex.fr/tei-istex.odd"></schemaRef><appInfo><application ident="pub2tei" version="1.0.10" when="2019-12-20"><label>pub2TEI-ISTEX</label><desc>A set of style sheets for 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<ref target="http://www.tei-c.org/">We use TEI</ref></desc></application></appInfo></encodingDesc><profileDesc><abstract xml:lang="en" style="main"><head>Abstract</head><p>Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. NCKX3 (gene <hi rend="italic">SLC24A3</hi>), a potassium‐dependent sodium‐/calcium exchanger, plays a critical role in the transport of one intracellular calcium and potassium ion across the cell membrane in exchange for four extracellular sodium ions. <hi rend="italic">NCKX3</hi> transcripts are most abundant in the brain and smooth muscle, but many other tissues, in particular, the uterus, aorta and intestine, also express this gene at lower levels. However, the expression and physiological roles of NCKX3 in the uterus of rats during the estrous cycle are unknown. Thus, we examined the uterine expression of NCKX3 mRNA and protein at different stages of the estrous cycle in mature and immature female rats in the absence or presence of the sex‐steroid hormones estrogen (E2) and progesterone (P4). During the estrous cycle, uterine expression of NCKX3 mRNA and protein was enhanced up to 4.0‐ and 2.5‐fold, respectively, at proestrus compared to during estrus and diestrus. To examine the effect of sex steroids on NCKX3 regulation in the uterus, immature female rats were treated with E2 (40 µg/kg body weight; BW), P4 (4 mg/kg BW), or E2 plus P4 for 3 days. The expression of NCKX3 mRNA and protein was induced by E2, whereas P4 antagonized E2‐induced NCKX3 expression. Subsequent immunohistochemical analysis revealed that uterine NCKX3 protein was abundantly localized in the cytoplasm of luminal and glandular epithelial cells throughout the estrous cycle. Taken together, these results indicate that uterine NCKX3 is abundantly expressed in the uterus and that its expression is regulated by the steroid hormones, E2 and P4. These findings suggest that NCKX3 may be involved in reproductive function during the estrous cycle in female rats. Mol. Reprod. Dev. 77:971–977, 2010. © 2010 Wiley‐Liss, Inc.</p></abstract><textClass><keywords rend="articleCategory"><term>Research Article</term></keywords><keywords rend="tocHeading1"><term>Research Articles</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc><revisionDesc><change when="2019-12-20" who="#istex" xml:id="pub2tei">formatting</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-PVSCBZ5C-X/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1098-2795</doi><issn type="print">1040-452X</issn><issn type="electronic">1098-2795</issn><idGroup><id type="product" value="MRD"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="MOLECULAR REPRODUCTION AND DEVELOPMENT">Molecular Reproduction and Development</title><title type="short">Mol. Reprod. Dev.</title></titleGroup></publicationMeta><publicationMeta level="part" position="110"><doi origin="wiley" registered="yes">10.1002/mrd.v77:11</doi><numberingGroup><numbering type="journalVolume" number="77">77</numbering><numbering type="journalIssue">11</numbering></numberingGroup><coverDate startDate="2010-11">November 2010</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="60" status="forIssue"><doi origin="wiley" registered="yes">10.1002/mrd.21245</doi><idGroup><id type="unit" value="MRD21245"></id></idGroup><countGroup><count type="pageTotal" number="7"></count></countGroup><titleGroup><title type="articleCategory">Research Article</title><title type="tocHeading1">Research Articles</title></titleGroup><copyright ownership="publisher">Copyright © 2010 Wiley‐Liss, Inc.</copyright><eventGroup><event type="manuscriptReceived" date="2010-05-26"></event><event type="manuscriptAccepted" date="2010-09-01"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:2.3.27 mode:FullText mathml2tex" date="2010-11-20"></event><event type="publishedOnlineAccepted" date="2010-10-01"></event><event type="firstOnline" date="2010-11-20"></event><event type="publishedOnlineFinalForm" date="2010-11-20"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-02-03"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-31"></event></eventGroup><numberingGroup><numbering type="pageFirst">971</numbering><numbering type="pageLast">977</numbering></numberingGroup><correspondenceTo>Laboratory of Veterinary Biochemistry and Molecular Biology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk 361‐763, Republic of Korea.</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:MRD.MRD21245.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="3"></count><count type="tableTotal" number="0"></count><count type="referenceTotal" number="29"></count><count type="wordTotal" number="4941"></count></countGroup><titleGroup><title type="main" xml:lang="en">Uterine expression of sodium/potassium/calcium exchanger 3 and its regulation by sex‐steroid hormones during the estrous cycle of rats</title><title type="short" xml:lang="en">NCKX3 IS REGULATED BY ESTROGEN AND PROGESTERONE</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Hyun</givenNames><familyName>Yang</familyName></personName></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Yeong‐Min</givenNames><familyName>Yoo</familyName></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Eui‐Man</givenNames><familyName>Jung</familyName></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Kyung‐Chul</givenNames><familyName>Choi</familyName></personName></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Eui‐Bae</givenNames><familyName>Jeung</familyName></personName><contactDetails><email>ebjeung@chungbuk.ac.kr</email></contactDetails></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="KR" type="organization"><unparsedAffiliation>Laboratory of Veterinary Biochemistry and Molecular Biology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea</unparsedAffiliation></affiliation></affiliationGroup><fundingInfo><fundingAgency>NRF of Korea</fundingAgency><fundingNumber>2010‐0011433</fundingNumber></fundingInfo><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. NCKX3 (gene <i>SLC24A3</i>), a potassium‐dependent sodium‐/calcium exchanger, plays a critical role in the transport of one intracellular calcium and potassium ion across the cell membrane in exchange for four extracellular sodium ions. <i>NCKX3</i> transcripts are most abundant in the brain and smooth muscle, but many other tissues, in particular, the uterus, aorta and intestine, also express this gene at lower levels. However, the expression and physiological roles of NCKX3 in the uterus of rats during the estrous cycle are unknown. Thus, we examined the uterine expression of NCKX3 mRNA and protein at different stages of the estrous cycle in mature and immature female rats in the absence or presence of the sex‐steroid hormones estrogen (E2) and progesterone (P4). During the estrous cycle, uterine expression of NCKX3 mRNA and protein was enhanced up to 4.0‐ and 2.5‐fold, respectively, at proestrus compared to during estrus and diestrus. To examine the effect of sex steroids on NCKX3 regulation in the uterus, immature female rats were treated with E2 (40 µg/kg body weight; BW), P4 (4 mg/kg BW), or E2 plus P4 for 3 days. The expression of NCKX3 mRNA and protein was induced by E2, whereas P4 antagonized E2‐induced NCKX3 expression. Subsequent immunohistochemical analysis revealed that uterine NCKX3 protein was abundantly localized in the cytoplasm of luminal and glandular epithelial cells throughout the estrous cycle. Taken together, these results indicate that uterine NCKX3 is abundantly expressed in the uterus and that its expression is regulated by the steroid hormones, E2 and P4. These findings suggest that NCKX3 may be involved in reproductive function during the estrous cycle in female rats. Mol. Reprod. Dev. 77:971–977, 2010. © 2010 Wiley‐Liss, Inc.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Uterine expression of sodium/potassium/calcium exchanger 3 and its regulation by sex‐steroid hormones during the estrous cycle of rats</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>NCKX3 IS REGULATED BY ESTROGEN AND PROGESTERONE</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Uterine expression of sodium/potassium/calcium exchanger 3 and its regulation by sex‐steroid hormones during the estrous cycle of rats</title></titleInfo><name type="personal"><namePart type="given">Hyun</namePart><namePart type="family">Yang</namePart><affiliation>Laboratory of Veterinary Biochemistry and Molecular Biology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Yeong‐Min</namePart><namePart type="family">Yoo</namePart><affiliation>Laboratory of Veterinary Biochemistry and Molecular Biology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Eui‐Man</namePart><namePart type="family">Jung</namePart><affiliation>Laboratory of Veterinary Biochemistry and Molecular Biology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Kyung‐Chul</namePart><namePart type="family">Choi</namePart><affiliation>Laboratory of Veterinary Biochemistry and Molecular Biology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Eui‐Bae</namePart><namePart type="family">Jeung</namePart><affiliation>Laboratory of Veterinary Biochemistry and Molecular Biology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea</affiliation><affiliation>E-mail: ebjeung@chungbuk.ac.kr</affiliation><affiliation>Correspondence address: Laboratory of Veterinary Biochemistry and Molecular Biology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk 361‐763, Republic of Korea.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2010-11</dateIssued><dateCaptured encoding="w3cdtf">2010-05-26</dateCaptured><dateValid encoding="w3cdtf">2010-09-01</dateValid><copyrightDate encoding="w3cdtf">2010</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="figures">3</extent><extent unit="tables">0</extent><extent unit="references">29</extent><extent unit="words">4941</extent></physicalDescription><abstract lang="en">Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. NCKX3 (gene SLC24A3), a potassium‐dependent sodium‐/calcium exchanger, plays a critical role in the transport of one intracellular calcium and potassium ion across the cell membrane in exchange for four extracellular sodium ions. NCKX3 transcripts are most abundant in the brain and smooth muscle, but many other tissues, in particular, the uterus, aorta and intestine, also express this gene at lower levels. However, the expression and physiological roles of NCKX3 in the uterus of rats during the estrous cycle are unknown. Thus, we examined the uterine expression of NCKX3 mRNA and protein at different stages of the estrous cycle in mature and immature female rats in the absence or presence of the sex‐steroid hormones estrogen (E2) and progesterone (P4). During the estrous cycle, uterine expression of NCKX3 mRNA and protein was enhanced up to 4.0‐ and 2.5‐fold, respectively, at proestrus compared to during estrus and diestrus. To examine the effect of sex steroids on NCKX3 regulation in the uterus, immature female rats were treated with E2 (40 µg/kg body weight; BW), P4 (4 mg/kg BW), or E2 plus P4 for 3 days. The expression of NCKX3 mRNA and protein was induced by E2, whereas P4 antagonized E2‐induced NCKX3 expression. Subsequent immunohistochemical analysis revealed that uterine NCKX3 protein was abundantly localized in the cytoplasm of luminal and glandular epithelial cells throughout the estrous cycle. Taken together, these results indicate that uterine NCKX3 is abundantly expressed in the uterus and that its expression is regulated by the steroid hormones, E2 and P4. These findings suggest that NCKX3 may be involved in reproductive function during the estrous cycle in female rats. Mol. Reprod. Dev. 77:971–977, 2010. © 2010 Wiley‐Liss, Inc.</abstract><note type="funding">NRF of Korea - No. 2010‐0011433; </note><relatedItem type="host"><titleInfo><title>Molecular Reproduction and Development</title></titleInfo><titleInfo type="abbreviated"><title>Mol. Reprod. Dev.</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><subject><genre>article-category</genre><topic>Research Article</topic><topic>Research Articles</topic></subject><identifier type="ISSN">1040-452X</identifier><identifier type="eISSN">1098-2795</identifier><identifier type="DOI">10.1002/(ISSN)1098-2795</identifier><identifier type="PublisherID">MRD</identifier><part><date>2010</date><detail type="volume"><caption>vol.</caption><number>77</number></detail><detail type="issue"><caption>no.</caption><number>11</number></detail><extent unit="pages"><start>971</start><end>977</end><total>7</total></extent></part></relatedItem><relatedItem type="references" displayLabel="cit1"><titleInfo><title>Novel Calbindin‐D(9k) protein as a useful biomarker for environmental estrogenic compounds in the uterus of immature rats</title></titleInfo><name type="personal"><namePart type="given">BS</namePart><namePart type="family">An</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KC</namePart><namePart type="family">Choi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SK</namePart><namePart type="family">Kang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">WS</namePart><namePart type="family">Hwang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">EB</namePart><namePart type="family">Jeung</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">An BS, Choi KC, Kang SK, Hwang WS, Jeung EB. 2003. Novel Calbindin‐D(9k) protein as a useful biomarker for environmental estrogenic compounds in the uterus of immature rats. Reprod Toxicol 17: 311–319.</note><part><date>2003</date><detail type="volume"><caption>vol.</caption><number>17</number></detail><extent unit="pages"><start>311</start><end>319</end></extent></part><relatedItem type="host"><titleInfo><title>Reprod Toxicol</title></titleInfo><part><date>2003</date><detail type="volume"><caption>vol.</caption><number>17</number></detail><extent unit="pages"><start>311</start><end>319</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit2"><titleInfo><title>Modulation of Ca2+ signaling by Na+/Ca2+ exchangers in mast cells</title></titleInfo><name type="personal"><namePart type="given">E</namePart><namePart type="family">Aneiros</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Philipp</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Lis</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Freichel</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Cavalie</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Aneiros E, Philipp S, Lis A, Freichel M, Cavalie A. 2005. Modulation of Ca2+ signaling by Na+/Ca2+ exchangers in mast cells. J Immunol 174: 119–130.</note><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>174</number></detail><extent unit="pages"><start>119</start><end>130</end></extent></part><relatedItem type="host"><titleInfo><title>J Immunol</title></titleInfo><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>174</number></detail><extent unit="pages"><start>119</start><end>130</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit3"><titleInfo><title>An estrogen‐responsive element mediates the transcriptional regulation of calbindin D‐9K gene in rat uterus</title></titleInfo><name type="personal"><namePart type="given">H</namePart><namePart type="family">Darwish</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Krisinger</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JD</namePart><namePart type="family">Furlow</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Smith</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">FE</namePart><namePart type="family">Murdoch</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HF</namePart><namePart type="family">DeLuca</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Darwish H, Krisinger J, Furlow JD, Smith C, Murdoch FE, DeLuca HF. 1991. An estrogen‐responsive element mediates the transcriptional regulation of calbindin D‐9K gene in rat uterus. J Biol Chem 266: 551–558.</note><part><date>1991</date><detail type="volume"><caption>vol.</caption><number>266</number></detail><extent unit="pages"><start>551</start><end>558</end></extent></part><relatedItem type="host"><titleInfo><title>J Biol Chem</title></titleInfo><part><date>1991</date><detail type="volume"><caption>vol.</caption><number>266</number></detail><extent unit="pages"><start>551</start><end>558</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit4"><titleInfo><title>Heparin‐binding EGF‐like growth factor gene is induced in the mouse uterus temporally by the blastocyst solely at the site of its apposition: A possible ligand for interaction with blastocyst EGF‐receptor in implantation</title></titleInfo><name type="personal"><namePart type="given">SK</namePart><namePart type="family">Das</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">XN</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">BC</namePart><namePart type="family">Paria</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Damm</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JA</namePart><namePart type="family">Abraham</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Klagsbrun</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">GK</namePart><namePart type="family">Andrews</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SK</namePart><namePart type="family">Dey</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Das SK, Wang XN, Paria BC, Damm D, Abraham JA, Klagsbrun M, Andrews GK, Dey SK. 1994. Heparin‐binding EGF‐like growth factor gene is induced in the mouse uterus temporally by the blastocyst solely at the site of its apposition: A possible ligand for interaction with blastocyst EGF‐receptor in implantation. Development 120: 1071–1083.</note><part><date>1994</date><detail type="volume"><caption>vol.</caption><number>120</number></detail><extent unit="pages"><start>1071</start><end>1083</end></extent></part><relatedItem type="host"><titleInfo><title>Development</title></titleInfo><part><date>1994</date><detail type="volume"><caption>vol.</caption><number>120</number></detail><extent unit="pages"><start>1071</start><end>1083</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit5"><titleInfo><title>Gene expression changes related to growth and differentiation in the fetal and juvenile reproductive system of the female rat: Evaluation of microarray results</title></titleInfo><name type="personal"><namePart type="given">GP</namePart><namePart type="family">Daston</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JM</namePart><namePart type="family">Naciff</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Daston GP, Naciff JM. 2005. Gene expression changes related to growth and differentiation in the fetal and juvenile reproductive system of the female rat: Evaluation of microarray results. Reprod Toxicol 19: 381–394.</note><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>19</number></detail><extent unit="pages"><start>381</start><end>394</end></extent></part><relatedItem type="host"><titleInfo><title>Reprod Toxicol</title></titleInfo><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>19</number></detail><extent unit="pages"><start>381</start><end>394</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit6"><titleInfo><title>The epithelial calcium channels, TRPV5 & TRP V6: From identification towards regulation</title></titleInfo><name type="personal"><namePart type="given">E</namePart><namePart type="family">den Dekker</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JG</namePart><namePart type="family">Hoenderop</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B</namePart><namePart type="family">Nilius</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">RJ</namePart><namePart type="family">Bindels</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">den Dekker E, Hoenderop JG, Nilius B, Bindels RJ. 2003. The epithelial calcium channels, TRPV5 & TRP V6: From identification towards regulation. Cell Calcium 33: 497–507.</note><part><date>2003</date><detail type="volume"><caption>vol.</caption><number>33</number></detail><extent unit="pages"><start>497</start><end>507</end></extent></part><relatedItem type="host"><titleInfo><title>Cell Calcium</title></titleInfo><part><date>2003</date><detail type="volume"><caption>vol.</caption><number>33</number></detail><extent unit="pages"><start>497</start><end>507</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit7"><titleInfo><title>Progesterone stimulates calcitonin gene expression in the uterus during implantation</title></titleInfo><name type="personal"><namePart type="given">YQ</namePart><namePart type="family">Ding</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">LJ</namePart><namePart type="family">Zhu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MK</namePart><namePart type="family">Bagchi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">IC</namePart><namePart type="family">Bagchi</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Ding YQ, Zhu LJ, Bagchi MK, Bagchi IC. 1994. Progesterone stimulates calcitonin gene expression in the uterus during implantation. Endocrinology 135: 2265–2274.</note><part><date>1994</date><detail type="volume"><caption>vol.</caption><number>135</number></detail><extent unit="pages"><start>2265</start><end>2274</end></extent></part><relatedItem type="host"><titleInfo><title>Endocrinology</title></titleInfo><part><date>1994</date><detail type="volume"><caption>vol.</caption><number>135</number></detail><extent unit="pages"><start>2265</start><end>2274</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit8"><titleInfo><title>Novel role for K+‐dependent Na+/Ca2+ exchangers in regulation of cytoplasmic free Ca2+ and contractility in arterial smooth muscle</title></titleInfo><name type="personal"><namePart type="given">H</namePart><namePart type="family">Dong</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Jiang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">CR</namePart><namePart type="family">Triggle</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">X</namePart><namePart type="family">Li</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Lytton</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Dong H, Jiang Y, Triggle CR, Li X, Lytton J. 2006. Novel role for K+‐dependent Na+/Ca2+ exchangers in regulation of cytoplasmic free Ca2+ and contractility in arterial smooth muscle. Am J Physiol Heart Circ Physiol 291: H1226–H1235.</note><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>291</number></detail><extent unit="pages"><start>H1226</start><end>H1235</end></extent></part><relatedItem type="host"><titleInfo><title>Am J Physiol Heart Circ Physiol</title></titleInfo><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>291</number></detail><extent unit="pages"><start>H1226</start><end>H1235</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit9"><titleInfo><title>Calcium transporters and signalling in smooth muscles</title></titleInfo><name type="personal"><namePart type="given">R</namePart><namePart type="family">Floyd</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Wray</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Floyd R, Wray S. 2007. Calcium transporters and signalling in smooth muscles. Cell Calcium 42: 467–476.</note><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>42</number></detail><extent unit="pages"><start>467</start><end>476</end></extent></part><relatedItem type="host"><titleInfo><title>Cell Calcium</title></titleInfo><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>42</number></detail><extent unit="pages"><start>467</start><end>476</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit10"><titleInfo><title>Induction of calbindin‐D9k messenger RNA and protein by maternal exposure to alkylphenols during late pregnancy in maternal and neonatal uteri of rats</title></titleInfo><name type="personal"><namePart type="given">EJ</namePart><namePart type="family">Hong</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KC</namePart><namePart type="family">Choi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">EB</namePart><namePart type="family">Jeung</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Hong EJ, Choi KC, Jeung EB. 2004. Induction of calbindin‐D9k messenger RNA and protein by maternal exposure to alkylphenols during late pregnancy in maternal and neonatal uteri of rats. Biol Reprod 71: 669–675.</note><part><date>2004</date><detail type="volume"><caption>vol.</caption><number>71</number></detail><extent unit="pages"><start>669</start><end>675</end></extent></part><relatedItem type="host"><titleInfo><title>Biol Reprod</title></titleInfo><part><date>2004</date><detail type="volume"><caption>vol.</caption><number>71</number></detail><extent unit="pages"><start>669</start><end>675</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit11"><titleInfo><title>Novel progestogenic activity of environmental endocrine disruptors in the upregulation of calbindin‐D9k in an immature mouse model</title></titleInfo><name type="personal"><namePart type="given">YW</namePart><namePart type="family">Jung</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">EJ</namePart><namePart type="family">Hong</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KC</namePart><namePart type="family">Choi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">EB</namePart><namePart type="family">Jeung</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Jung YW, Hong EJ, Choi KC, Jeung EB. 2005. Novel progestogenic activity of environmental endocrine disruptors in the upregulation of calbindin‐D9k in an immature mouse model. Toxicol Sci 83: 78–88.</note><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>83</number></detail><extent unit="pages"><start>78</start><end>88</end></extent></part><relatedItem type="host"><titleInfo><title>Toxicol Sci</title></titleInfo><part><date>2005</date><detail type="volume"><caption>vol.</caption><number>83</number></detail><extent unit="pages"><start>78</start><end>88</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit12"><titleInfo><title>Differential expression of uterine calcium transporter 1 and plasma membrane Ca2+ ATPase 1b during rat estrous cycle</title></titleInfo><name type="personal"><namePart type="given">HJ</namePart><namePart type="family">Kim</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">GS</namePart><namePart type="family">Lee</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">YK</namePart><namePart type="family">Ji</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KC</namePart><namePart type="family">Choi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">EB</namePart><namePart type="family">Jeung</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Kim HJ, Lee GS, Ji YK, Choi KC, Jeung EB. 2006. Differential expression of uterine calcium transporter 1 and plasma membrane Ca2+ ATPase 1b during rat estrous cycle. Am J Physiol Endocrinol Metab 291: E234–E241.</note><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>291</number></detail><extent unit="pages"><start>E234</start><end>E241</end></extent></part><relatedItem type="host"><titleInfo><title>Am J Physiol Endocrinol Metab</title></titleInfo><part><date>2006</date><detail type="volume"><caption>vol.</caption><number>291</number></detail><extent unit="pages"><start>E234</start><end>E241</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit13"><titleInfo><title>A cell cycle‐associated change in Ca2+ releasing activity leads to the generation of Ca2+ transients in mouse embryos during the first mitotic division</title></titleInfo><name type="personal"><namePart type="given">T</namePart><namePart type="family">Kono</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KT</namePart><namePart type="family">Jones</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Bos‐Mikich</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DG</namePart><namePart type="family">Whittingham</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Carroll</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Kono T, Jones KT, Bos‐Mikich A, Whittingham DG, Carroll J. 1996. A cell cycle‐associated change in Ca2+ releasing activity leads to the generation of Ca2+ transients in mouse embryos during the first mitotic division. J Cell Biol 132: 915–923.</note><part><date>1996</date><detail type="volume"><caption>vol.</caption><number>132</number></detail><extent unit="pages"><start>915</start><end>923</end></extent></part><relatedItem type="host"><titleInfo><title>J Cell Biol</title></titleInfo><part><date>1996</date><detail type="volume"><caption>vol.</caption><number>132</number></detail><extent unit="pages"><start>915</start><end>923</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit14"><titleInfo><title>Molecular cloning of a third member of the potassium‐dependent sodium‐calcium exchanger gene family, NCKX3</title></titleInfo><name type="personal"><namePart type="given">A</namePart><namePart type="family">Kraev</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">BD</namePart><namePart type="family">Quednau</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Leach</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">XF</namePart><namePart type="family">Li</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Dong</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Winkfein</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Perizzolo</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">X</namePart><namePart type="family">Cai</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">R</namePart><namePart type="family">Yang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KD</namePart><namePart type="family">Philipson</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Lytton</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Kraev A, Quednau BD, Leach S, Li XF, Dong H, Winkfein R, Perizzolo M, Cai X, Yang R, Philipson KD, Lytton J. 2001. Molecular cloning of a third member of the potassium‐dependent sodium‐calcium exchanger gene family, NCKX3. J Biol Chem 276: 23161–23172.</note><part><date>2001</date><detail type="volume"><caption>vol.</caption><number>276</number></detail><extent unit="pages"><start>23161</start><end>23172</end></extent></part><relatedItem type="host"><titleInfo><title>J Biol Chem</title></titleInfo><part><date>2001</date><detail type="volume"><caption>vol.</caption><number>276</number></detail><extent unit="pages"><start>23161</start><end>23172</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit15"><titleInfo><title>Calbindin‐D9k mRNA is tightly regulated during the estrous cycle in the rat uterus</title></titleInfo><name type="personal"><namePart type="given">J</namePart><namePart type="family">Krisinger</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JL</namePart><namePart type="family">Dann</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">WD</namePart><namePart type="family">Currie</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">EB</namePart><namePart type="family">Jeung</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">PC</namePart><namePart type="family">Leung</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Krisinger J, Dann JL, Currie WD, Jeung EB, Leung PC. 1992. Calbindin‐D9k mRNA is tightly regulated during the estrous cycle in the rat uterus. Mol Cell Endocrinol 86: 119–123.</note><part><date>1992</date><detail type="volume"><caption>vol.</caption><number>86</number></detail><extent unit="pages"><start>119</start><end>123</end></extent></part><relatedItem type="host"><titleInfo><title>Mol Cell Endocrinol</title></titleInfo><part><date>1992</date><detail type="volume"><caption>vol.</caption><number>86</number></detail><extent unit="pages"><start>119</start><end>123</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit16"><titleInfo><title>Development of in vitro fertilized mouse embryos exposed to ethanol during the preimplantation period: Accelerated embryogenesis at subtoxic levels</title></titleInfo><name type="personal"><namePart type="given">RE</namePart><namePart type="family">Leach</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JJ</namePart><namePart type="family">Stachecki</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DR</namePart><namePart type="family">Armant</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Leach RE, Stachecki JJ, Armant DR. 1993. Development of in vitro fertilized mouse embryos exposed to ethanol during the preimplantation period: Accelerated embryogenesis at subtoxic levels. Teratology 47: 57–64.</note><part><date>1993</date><detail type="volume"><caption>vol.</caption><number>47</number></detail><extent unit="pages"><start>57</start><end>64</end></extent></part><relatedItem type="host"><titleInfo><title>Teratology</title></titleInfo><part><date>1993</date><detail type="volume"><caption>vol.</caption><number>47</number></detail><extent unit="pages"><start>57</start><end>64</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit17"><titleInfo><title>Uterine TRPV6 expression during the estrous cycle and pregnancy in a mouse model</title></titleInfo><name type="personal"><namePart type="given">GS</namePart><namePart type="family">Lee</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">EB</namePart><namePart type="family">Jeung</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Lee GS, Jeung EB. 2007. Uterine TRPV6 expression during the estrous cycle and pregnancy in a mouse model. Am J Physiol Endocrinol Metab 293: E132–E138.</note><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>293</number></detail><extent unit="pages"><start>E132</start><end>E138</end></extent></part><relatedItem type="host"><titleInfo><title>Am J Physiol Endocrinol Metab</title></titleInfo><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>293</number></detail><extent unit="pages"><start>E132</start><end>E138</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit18"><titleInfo><title>Endometrial expression of calbindin (CaBP)‐d28k but not CaBP‐d9k in primates implies evolutionary changes and functional redundancy of calbindins at implantation</title></titleInfo><name type="personal"><namePart type="given">KC</namePart><namePart type="family">Luu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">GY</namePart><namePart type="family">Nie</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Hampton</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">GQ</namePart><namePart type="family">Fu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">YX</namePart><namePart type="family">Liu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">LA</namePart><namePart type="family">Salamonsen</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Luu KC, Nie GY, Hampton A, Fu GQ, Liu YX, Salamonsen LA. 2004a. Endometrial expression of calbindin (CaBP)‐d28k but not CaBP‐d9k in primates implies evolutionary changes and functional redundancy of calbindins at implantation. Reproduction 128: 433–441.</note><part><date>2004</date><detail type="volume"><caption>vol.</caption><number>128</number></detail><extent unit="pages"><start>433</start><end>441</end></extent></part><relatedItem type="host"><titleInfo><title>Reproduction</title></titleInfo><part><date>2004</date><detail type="volume"><caption>vol.</caption><number>128</number></detail><extent unit="pages"><start>433</start><end>441</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit19"><titleInfo><title>Endometrial calbindins are critical for embryo implantation: Evidence from in vivo use of morpholino antisense oligonucleotides</title></titleInfo><name type="personal"><namePart type="given">KC</namePart><namePart type="family">Luu</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">GY</namePart><namePart type="family">Nie</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">LA</namePart><namePart type="family">Salamonsen</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Luu KC, Nie GY, Salamonsen LA. 2004b. Endometrial calbindins are critical for embryo implantation: Evidence from in vivo use of morpholino antisense oligonucleotides. Proc Natl Acad Sci USA 101: 8028–8033.</note><part><date>2004</date><detail type="volume"><caption>vol.</caption><number>101</number></detail><extent unit="pages"><start>8028</start><end>8033</end></extent></part><relatedItem type="host"><titleInfo><title>Proc Natl Acad Sci USA</title></titleInfo><part><date>2004</date><detail type="volume"><caption>vol.</caption><number>101</number></detail><extent unit="pages"><start>8028</start><end>8033</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit20"><titleInfo><title>K+‐dependent Na+/Ca2+ exchangers in the brain</title></titleInfo><name type="personal"><namePart type="given">J</namePart><namePart type="family">Lytton</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">XF</namePart><namePart type="family">Li</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Dong</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Kraev</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Lytton J, Li XF, Dong H, Kraev A. 2002. K+‐dependent Na+/Ca2+ exchangers in the brain. Ann N Y Acad Sci 976: 382–393.</note><part><date>2002</date><detail type="volume"><caption>vol.</caption><number>976</number></detail><extent unit="pages"><start>382</start><end>393</end></extent></part><relatedItem type="host"><titleInfo><title>Ann N Y Acad Sci</title></titleInfo><part><date>2002</date><detail type="volume"><caption>vol.</caption><number>976</number></detail><extent unit="pages"><start>382</start><end>393</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit21"><titleInfo><title>Molecular cloning and functional expression of the cardiac sarcolemmal Na(+)‐Ca2+ exchanger</title></titleInfo><name type="personal"><namePart type="given">DA</namePart><namePart type="family">Nicoll</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Longoni</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KD</namePart><namePart type="family">Philipson</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Nicoll DA, Longoni S, Philipson KD. 1990. Molecular cloning and functional expression of the cardiac sarcolemmal Na(+)‐Ca2+ exchanger. Science 250: 562–565.</note><part><date>1990</date><detail type="volume"><caption>vol.</caption><number>250</number></detail><extent unit="pages"><start>562</start><end>565</end></extent></part><relatedItem type="host"><titleInfo><title>Science</title></titleInfo><part><date>1990</date><detail type="volume"><caption>vol.</caption><number>250</number></detail><extent unit="pages"><start>562</start><end>565</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit22"><titleInfo><title>Complex regulation of calcium‐binding protein D9k (calbindin‐D(9k)) in mouse the uterus during early pregnancy at the site of embryo implantation</title></titleInfo><name type="personal"><namePart type="given">GY</namePart><namePart type="family">Nie</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Li</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Minoura</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JK</namePart><namePart type="family">Findlay</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">LA</namePart><namePart type="family">Salamonsen</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Nie GY, Li Y, Wang J, Minoura H, Findlay JK, Salamonsen LA. 2000. Complex regulation of calcium‐binding protein D9k (calbindin‐D(9k)) in mouse the uterus during early pregnancy at the site of embryo implantation. Biol Reprod 62: 27–36.</note><part><date>2000</date><detail type="volume"><caption>vol.</caption><number>62</number></detail><extent unit="pages"><start>27</start><end>36</end></extent></part><relatedItem type="host"><titleInfo><title>Biol Reprod</title></titleInfo><part><date>2000</date><detail type="volume"><caption>vol.</caption><number>62</number></detail><extent unit="pages"><start>27</start><end>36</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit23"><titleInfo><title>Genes involved in implantation</title></titleInfo><name type="personal"><namePart type="given">LA</namePart><namePart type="family">Salamonsen</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G</namePart><namePart type="family">Nie</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Dimitriadis</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Robb</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JK</namePart><namePart type="family">Findlay</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Salamonsen LA, Nie G, Dimitriadis E, Robb L, Findlay JK. 2001. Genes involved in implantation. Reprod Fertil Dev 13: 41–49.</note><part><date>2001</date><detail type="volume"><caption>vol.</caption><number>13</number></detail><extent unit="pages"><start>41</start><end>49</end></extent></part><relatedItem type="host"><titleInfo><title>Reprod Fertil Dev</title></titleInfo><part><date>2001</date><detail type="volume"><caption>vol.</caption><number>13</number></detail><extent unit="pages"><start>41</start><end>49</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit24"><titleInfo><title>Relationship of ion channel activity to control of myometrial calcium</title></titleInfo><name type="personal"><namePart type="given">BM</namePart><namePart type="family">Sanborn</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Sanborn BM. 2000. Relationship of ion channel activity to control of myometrial calcium. J Soc Gynecol Invest 7: 4–11.</note><part><date>2000</date><detail type="volume"><caption>vol.</caption><number>7</number></detail><extent unit="pages"><start>4</start><end>11</end></extent></part><relatedItem type="host"><titleInfo><title>J Soc Gynecol Invest</title></titleInfo><part><date>2000</date><detail type="volume"><caption>vol.</caption><number>7</number></detail><extent unit="pages"><start>4</start><end>11</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit25"><titleInfo><title>Expression of calcium binding protein D‐9k messenger RNA in the mouse uterine endometrium during implantation</title></titleInfo><name type="personal"><namePart type="given">K</namePart><namePart type="family">Tatsumi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Higuchi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">H</namePart><namePart type="family">Fujiwara</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Nakayama</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Itoh</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">T</namePart><namePart type="family">Mori</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Fujii</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Fujita</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Tatsumi K, Higuchi T, Fujiwara H, Nakayama T, Itoh K, Mori T, Fujii S, Fujita J. 1999. Expression of calcium binding protein D‐9k messenger RNA in the mouse uterine endometrium during implantation. Mol Hum Reprod 5: 153–161.</note><part><date>1999</date><detail type="volume"><caption>vol.</caption><number>5</number></detail><extent unit="pages"><start>153</start><end>161</end></extent></part><relatedItem type="host"><titleInfo><title>Mol Hum Reprod</title></titleInfo><part><date>1999</date><detail type="volume"><caption>vol.</caption><number>5</number></detail><extent unit="pages"><start>153</start><end>161</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit26"><titleInfo><title>Molecular cloning of a novel potassium‐dependent sodium‐calcium exchanger from rat brain</title></titleInfo><name type="personal"><namePart type="given">M</namePart><namePart type="family">Tsoi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KH</namePart><namePart type="family">Rhee</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Bungard</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">XF</namePart><namePart type="family">Li</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SL</namePart><namePart type="family">Lee</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">RN</namePart><namePart type="family">Auer</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Lytton</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Tsoi M, Rhee KH, Bungard D, Li XF, Lee SL, Auer RN, Lytton J. 1998. Molecular cloning of a novel potassium‐dependent sodium‐calcium exchanger from rat brain. J Biol Chem 273: 4155–4162.</note><part><date>1998</date><detail type="volume"><caption>vol.</caption><number>273</number></detail><extent unit="pages"><start>4155</start><end>4162</end></extent></part><relatedItem type="host"><titleInfo><title>J Biol Chem</title></titleInfo><part><date>1998</date><detail type="volume"><caption>vol.</caption><number>273</number></detail><extent unit="pages"><start>4155</start><end>4162</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit27"><titleInfo><title>Expression of calcitonin receptors in mouse preimplantation embryos and their function in the regulation of blastocyst differentiation by calcitonin</title></titleInfo><name type="personal"><namePart type="given">J</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">UK</namePart><namePart type="family">Rout</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">IC</namePart><namePart type="family">Bagchi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DR</namePart><namePart type="family">Armant</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Wang J, Rout UK, Bagchi IC, Armant DR. 1998. Expression of calcitonin receptors in mouse preimplantation embryos and their function in the regulation of blastocyst differentiation by calcitonin. Development 125: 4293–4302.</note><part><date>1998</date><detail type="volume"><caption>vol.</caption><number>125</number></detail><extent unit="pages"><start>4293</start><end>4302</end></extent></part><relatedItem type="host"><titleInfo><title>Development</title></titleInfo><part><date>1998</date><detail type="volume"><caption>vol.</caption><number>125</number></detail><extent unit="pages"><start>4293</start><end>4302</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit28"><titleInfo><title>Calcium signaling and uterine contractility</title></titleInfo><name type="personal"><namePart type="given">S</namePart><namePart type="family">Wray</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Jones</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Kupittayanant</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y</namePart><namePart type="family">Li</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Matthew</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E</namePart><namePart type="family">Monir‐Bishty</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">K</namePart><namePart type="family">Noble</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SJ</namePart><namePart type="family">Pierce</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Quenby</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">AV</namePart><namePart type="family">Shmygol</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Wray S, Jones K, Kupittayanant S, Li Y, Matthew A, Monir‐Bishty E, Noble K, Pierce SJ, Quenby S, Shmygol AV. 2003. Calcium signaling and uterine contractility. J Soc Gynecol Invest 10: 252–264.</note><part><date>2003</date><detail type="volume"><caption>vol.</caption><number>10</number></detail><extent unit="pages"><start>252</start><end>264</end></extent></part><relatedItem type="host"><titleInfo><title>J Soc Gynecol Invest</title></titleInfo><part><date>2003</date><detail type="volume"><caption>vol.</caption><number>10</number></detail><extent unit="pages"><start>252</start><end>264</end></extent></part></relatedItem></relatedItem><relatedItem type="references" displayLabel="cit29"><titleInfo><title>Sodium/potassium/calcium exchanger 3 is regulated by the steroid hormones estrogen and progesterone in the uterus of mice during the estrous cycle</title></titleInfo><name type="personal"><namePart type="given">H</namePart><namePart type="family">Yang</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">GS</namePart><namePart type="family">Lee</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">YM</namePart><namePart type="family">Yoo</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">KC</namePart><namePart type="family">Choi</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">EB</namePart><namePart type="family">Jeung</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Yang H, Lee GS, Yoo YM, Choi KC, Jeung EB. 2009. Sodium/potassium/calcium exchanger 3 is regulated by the steroid hormones estrogen and progesterone in the uterus of mice during the estrous cycle. Biochem Biophys Res Commun 385: 279–283.</note><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>385</number></detail><extent unit="pages"><start>279</start><end>283</end></extent></part><relatedItem type="host"><titleInfo><title>Biochem Biophys Res Commun</title></titleInfo><part><date>2009</date><detail type="volume"><caption>vol.</caption><number>385</number></detail><extent unit="pages"><start>279</start><end>283</end></extent></part></relatedItem></relatedItem><identifier type="istex">9ACC4BAFBB7AA1E827E1BEA3B05F77C434BD0426</identifier><identifier type="ark">ark:/67375/WNG-PVSCBZ5C-X</identifier><identifier type="DOI">10.1002/mrd.21245</identifier><identifier type="ArticleID">MRD21245</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2010 Wiley‐Liss, Inc.</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-L0C46X92-X">wiley</recordContentSource><recordOrigin>Converted from (version ) to MODS version 3.6.</recordOrigin><recordCreationDate encoding="w3cdtf">2019-11-16</recordCreationDate></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-PVSCBZ5C-X/record.json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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