Detection and typing of human papillomaviruses by in situ hybridization with biotinylated oligonucleotide mixtures
Identifieur interne : 000A92 ( Istex/Corpus ); précédent : 000A91; suivant : 000A93Detection and typing of human papillomaviruses by in situ hybridization with biotinylated oligonucleotide mixtures
Auteurs : Marie-Lise Jourdan ; Alain Goudeau ; Martine Joannes ; C Me Barranger ; Gérard SomméSource :
- Journal of Medical Virology [ 0146-6615 ] ; 1995-03.
Abstract
The value of biotinylated Oligonucleotide probes for screening and typing by in situ hybridization of the most frequent genital human papillomavirus infections (HPVs 6,11,16,18, 31, and 33) was assessed. Optimal hybridization conditions were defined on a panel of paraffin‐embedded tissue sections previously characterized with HPV full genome probes. Mixtures of oligonucleotides rather than single oligonucleotides were used to improve sensitivity and specificity. All HPV‐positive specimens were detected by the screening mixture with a sensitivity and specificity similar to that of full genome probes. Typing mixtures were highly specific for each HPV type. This study confirms the potential of Oligonucleotide probes for detecting and typing HPV infections. © 1995 Wiley‐Liss, Inc.
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DOI: 10.1002/jmv.1890450310
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This study confirms the potential of Oligonucleotide probes for detecting and typing HPV infections. © 1995 Wiley‐Liss, Inc.</p></abstract><textClass><keywords xml:lang="en"><term xml:id="kwd1">HPV</term><term xml:id="kwd2">human papillomavirus</term><term xml:id="kwd3">cervix</term><term xml:id="kwd4">in situ hybridization</term><term xml:id="kwd5">oligonucleotides</term></keywords><keywords rend="articleCategory"><term>Article</term></keywords><keywords rend="tocHeading1"><term>Articles</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc><revisionDesc><change when="2019-12-20" who="#istex" xml:id="pub2tei">formatting</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-K1X6D7Q8-C/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>New York</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1096-9071</doi><issn type="print">0146-6615</issn><issn type="electronic">1096-9071</issn><idGroup><id type="product" value="JMV"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="JOURNAL OF MEDICAL VIROLOGY">Journal of Medical Virology</title><title type="short">J. 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Virol.</title></titleGroup></publicationMeta><publicationMeta level="part" position="30"><doi origin="wiley" registered="yes">10.1002/jmv.v45:3</doi><numberingGroup><numbering type="journalVolume" number="45">45</numbering><numbering type="journalIssue">3</numbering></numberingGroup><coverDate startDate="1995-03">March 1995</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="10" status="forIssue"><doi origin="wiley" registered="yes">10.1002/jmv.1890450310</doi><idGroup><id type="unit" value="JMV1890450310"></id></idGroup><countGroup><count type="pageTotal" number="7"></count></countGroup><titleGroup><title type="articleCategory">Article</title><title type="tocHeading1">Articles</title></titleGroup><copyright ownership="publisher">Copyright © 1995 Wiley‐Liss, Inc., A Wiley Company</copyright><eventGroup><event type="manuscriptAccepted" date="1994-08-16"></event><event type="firstOnline" date="2005-12-07"></event><event type="publishedOnlineFinalForm" date="2005-12-07"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:2.3.6 mode:FullText source:HeaderRef result:HeaderRef" date="2010-04-20"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:4.0.1" date="2014-03-20"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-30"></event></eventGroup><numberingGroup><numbering type="pageFirst">293</numbering><numbering type="pageLast">299</numbering></numberingGroup><correspondenceTo>Département de Microbiologie Médicale et Moléculaire, Unité de Virologie, URA CNRS 1334, CHU Bretonneau, 37044 Tours cedex, France===</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:JMV.JMV1890450310.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="2"></count><count type="tableTotal" number="4"></count><count type="referenceTotal" number="23"></count></countGroup><titleGroup><title type="main" xml:lang="en">Detection and typing of human papillomaviruses by in situ hybridization with biotinylated oligonucleotide mixtures</title><title type="short" xml:lang="en">In Situ Hybridization of HCV</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Marie‐Lise</givenNames><familyName>Jourdan</familyName></personName></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Alain</givenNames><familyName>Goudeau</familyName></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Martine</givenNames><familyName>Joannes</familyName></personName></creator><creator xml:id="au4" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Cǒme</givenNames><familyName>Barranger</familyName></personName></creator><creator xml:id="au5" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Gérard</givenNames><familyName>Sommé</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="FR" type="organization"><unparsedAffiliation>Département de Microbiologie Médicate et Moléculaire, Unité de Virologie, URA CNRS 1334, CHU Bretonneau, Tours, France</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="FR" type="organization"><unparsedAffiliation>Clonatec, Paris, France</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">HPV</keyword><keyword xml:id="kwd2">human papillomavirus</keyword><keyword xml:id="kwd3">cervix</keyword><keyword xml:id="kwd4">in situ hybridization</keyword><keyword xml:id="kwd5">oligonucleotides</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>The value of biotinylated Oligonucleotide probes for screening and typing by in situ hybridization of the most frequent genital human papillomavirus infections (HPVs 6,11,16,18, 31, and 33) was assessed. Optimal hybridization conditions were defined on a panel of paraffin‐embedded tissue sections previously characterized with HPV full genome probes. Mixtures of oligonucleotides rather than single oligonucleotides were used to improve sensitivity and specificity. All HPV‐positive specimens were detected by the screening mixture with a sensitivity and specificity similar to that of full genome probes. Typing mixtures were highly specific for each HPV type. This study confirms the potential of Oligonucleotide probes for detecting and typing HPV infections. © 1995 Wiley‐Liss, Inc.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Detection and typing of human papillomaviruses by in situ hybridization with biotinylated oligonucleotide mixtures</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>In Situ Hybridization of HCV</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Detection and typing of human papillomaviruses by in situ hybridization with biotinylated oligonucleotide mixtures</title></titleInfo><name type="personal"><namePart type="given">Marie‐Lise</namePart><namePart type="family">Jourdan</namePart><affiliation>Département de Microbiologie Médicate et Moléculaire, Unité de Virologie, URA CNRS 1334, CHU Bretonneau, Tours, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Alain</namePart><namePart type="family">Goudeau</namePart><affiliation>Département de Microbiologie Médicate et Moléculaire, Unité de Virologie, URA CNRS 1334, CHU Bretonneau, Tours, France</affiliation><affiliation>Correspondence address: Département de Microbiologie Médicale et Moléculaire, Unité de Virologie, URA CNRS 1334, CHU Bretonneau, 37044 Tours cedex, France===</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Martine</namePart><namePart type="family">Joannes</namePart><affiliation>Clonatec, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Cǒme</namePart><namePart type="family">Barranger</namePart><affiliation>Clonatec, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Gérard</namePart><namePart type="family">Sommé</namePart><affiliation>Clonatec, Paris, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">New York</placeTerm></place><dateIssued encoding="w3cdtf">1995-03</dateIssued><dateValid encoding="w3cdtf">1994-08-16</dateValid><copyrightDate encoding="w3cdtf">1995</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="figures">2</extent><extent unit="tables">4</extent><extent unit="references">23</extent></physicalDescription><abstract lang="en">The value of biotinylated Oligonucleotide probes for screening and typing by in situ hybridization of the most frequent genital human papillomavirus infections (HPVs 6,11,16,18, 31, and 33) was assessed. Optimal hybridization conditions were defined on a panel of paraffin‐embedded tissue sections previously characterized with HPV full genome probes. Mixtures of oligonucleotides rather than single oligonucleotides were used to improve sensitivity and specificity. All HPV‐positive specimens were detected by the screening mixture with a sensitivity and specificity similar to that of full genome probes. Typing mixtures were highly specific for each HPV type. This study confirms the potential of Oligonucleotide probes for detecting and typing HPV infections. © 1995 Wiley‐Liss, Inc.</abstract><subject lang="en"><genre>keywords</genre><topic>HPV</topic><topic>human papillomavirus</topic><topic>cervix</topic><topic>in situ hybridization</topic><topic>oligonucleotides</topic></subject><relatedItem type="host"><titleInfo><title>Journal of Medical Virology</title></titleInfo><titleInfo type="abbreviated"><title>J. Med. Virol.</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><subject><genre>article-category</genre><topic>Article</topic><topic>Articles</topic></subject><identifier type="ISSN">0146-6615</identifier><identifier type="eISSN">1096-9071</identifier><identifier type="DOI">10.1002/(ISSN)1096-9071</identifier><identifier type="PublisherID">JMV</identifier><part><date>1995</date><detail type="volume"><caption>vol.</caption><number>45</number></detail><detail type="issue"><caption>no.</caption><number>3</number></detail><extent unit="pages"><start>293</start><end>299</end><total>7</total></extent></part></relatedItem><relatedItem type="references" displayLabel="cit1"><titleInfo><title>In situ hybridization: an optimised detection protocol for a biotinylated DNA probe renders it more sensitive than a comparable 35S‐labelled probe</title></titleInfo><name type="personal"><namePart type="given">GM</namePart><namePart type="family">Allan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D</namePart><namePart type="family">Todd</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">JA</namePart><namePart type="family">Smyth</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">DP</namePart><namePart type="family">Mackie</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J</namePart><namePart type="family">Burns</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MS</namePart><namePart type="family">McNulty</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Allan GM, Todd D, Smyth JA, Mackie DP, Burns J, McNulty MS (1989): In situ hybridization: an optimised detection protocol for a biotinylated DNA probe renders it more sensitive than a comparable 35S‐labelled probe. 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