Natural and synthetic polymers
Identifieur interne : 000426 ( Istex/Corpus ); précédent : 000425; suivant : 000427Natural and synthetic polymers
Auteurs : P. D. CalvertSource :
- Nature [ 0028-0836 ] ; 1975-02-13.
Url:
DOI: 10.1038/253504b0
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<bdy>
SCIENTISTS have great trouble even in communicating the meaning of their work to each other. This was probably the main conclusion to be drawn from the symposium which, because of the lack of dialogue or (apparently) of flashes of inspiration, must be judged a failure. The reasons may be that the speakers did not address themselves sufficiently to areas of potential overlap, that the discussion was too limited or that the two subjects are irrelevant to each other.
Polymer 'science groups in the USA are increasingly turning their interest to biological macromolecules, spurred on by the increase in the fortunes of the NTH compared to those of the Defense Department a few years ago. This has resulted in work on solid state and solution properties of poly-saccharides and polypeptides, one obvious avenue, and in the study of collagen ultrastructure and its relationship to mechanical properties presented by R.'G. C. Arridge and L. Gathercole of Bristol and carried out jointly with Case Western Reserve University.
One thing that did emerge was the relative lack of understanding of physical aspects of enzyme structure such as the denaturation and renatura-tion processes, the nature of subunit interactions, and of questions such as "How large must a protein be to have a hydrophobic core?" posed by T. L. Blundell during the discussion. This was reinforced by the parallel between J. O. Thomas's review of work on chromatin structure at Cambridge and D. M. Sadler's of polymer crystallisation and morphology.' UQth topics are almost baroque in their complexity, the methocfs used ate completely different, yet the problems are very much related. It is to be hoped that researchers starting from the synthetic polymer direction can contribute to these subjects, though the immediate problem for a person used to working with kilograms of sample is to learn techniques for handling natural polymers, and here cooperation between the groups is essential.</bdy>
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