MersV1, France, Analysis, bibRecord, 000315

INTEREST OF A SIMPLE AND FAST METHOD FOR PLATELET VON WILLEBRAND FACTOR CHARACTERIZATION

Identifieur interne : 000315 ( France/Analysis ); précédent : 000314; suivant : 000316

INTEREST OF A SIMPLE AND FAST METHOD FOR PLATELET VON WILLEBRAND FACTOR CHARACTERIZATION

Auteurs : Christophe De Romeuf [France] ; Claudine Mazurier [France]

Source :

Thrombosis Research [ 0049-3848 ] ; 1996.

RBID : ISTEX:5C07843521B6C9D8626EDABC6CAE06D1A3B41347

English descriptors

Teeft :
- Appropriate treatment, Corresponding plasma, Former subtype, Gpib, Lysate, Lysates, Multimeric, Multimeric pattern, Multimers, Mutation, Normal individuals, Normal plasma, Normal platelet, Pellet, Platelet, Platelet gpib, Platelet lysate, Platelet lysates, Platelet vwfs, Protease, Protease inhibitors, Same point mutation, Thromb haemost, Weight multimers, Willebrand, Willebrand disease, Willebrand factor.

Abstract

Abstract: Quantitative or qualitative assay of platelet von Willebrand factor (vWF) is required for the classification of patients suffering from von Willebrand disease (vWD). The major interest of this classification is the administration of specific and appropriate treatment to each category of vWD patients. However, because platelet lysate is prepared from washed platelets, the analysis of platelet vWF is not performed in routine. To overcome this problem, platelet lysates were prepared either with a new method which does not require washing procedure or with the established protocol, then respective platelet vWF characteristics were compared. Our data show that the two methods provide comparable information required for the characterization of types 1 and 2 vWD patients. With this new procedure, complete phenotypic data including the characteristics of platelet vWF can be obtained from most of the vWD patients.

Url:

https://api.istex.fr/ark:/67375/6H6-Z19KCL6Q-2/fulltext.pdf

DOI: 10.1016/0049-3848(96)00137-5

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Istex, to step Corpus: 000263
to stream Istex, to step Curation: 000263
to stream Istex, to step Checkpoint: 001619
to stream Main, to step Merge: 003F38
to stream Main, to step Curation: 003E83
to stream Main, to step Exploration: 003E83
to stream France, to step Extraction: 000315

Links to Exploration step

ISTEX:5C07843521B6C9D8626EDABC6CAE06D1A3B41347

Le document en format XML

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<term>Lysates</term>
<term>Multimeric</term>
<term>Multimeric pattern</term>
<term>Multimers</term>
<term>Mutation</term>
<term>Normal individuals</term>
<term>Normal plasma</term>
<term>Normal platelet</term>
<term>Pellet</term>
<term>Platelet</term>
<term>Platelet gpib</term>
<term>Platelet lysate</term>
<term>Platelet lysates</term>
<term>Platelet vwfs</term>
<term>Protease</term>
<term>Protease inhibitors</term>
<term>Same point mutation</term>
<term>Thromb haemost</term>
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<front><div type="abstract" xml:lang="en">Abstract: Quantitative or qualitative assay of platelet von Willebrand factor (vWF) is required for the classification of patients suffering from von Willebrand disease (vWD). The major interest of this classification is the administration of specific and appropriate treatment to each category of vWD patients. However, because platelet lysate is prepared from washed platelets, the analysis of platelet vWF is not performed in routine. To overcome this problem, platelet lysates were prepared either with a new method which does not require washing procedure or with the established protocol, then respective platelet vWF characteristics were compared. Our data show that the two methods provide comparable information required for the characterization of types 1 and 2 vWD patients. With this new procedure, complete phenotypic data including the characteristics of platelet vWF can be obtained from most of the vWD patients.</div>
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   |texte=   INTEREST OF A SIMPLE AND FAST METHOD FOR PLATELET VON WILLEBRAND FACTOR CHARACTERIZATION
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INTEREST OF A SIMPLE AND FAST METHOD FOR PLATELET VON WILLEBRAND FACTOR CHARACTERIZATION

INTEREST OF A SIMPLE AND FAST METHOD FOR PLATELET VON WILLEBRAND FACTOR CHARACTERIZATION

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri