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<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">The Association between Sleep Problems and Psychotic Symptoms in the General Population: A Global Perspective</title>
<author>
<name sortKey="Koyanagi, Ai" sort="Koyanagi, Ai" uniqKey="Koyanagi A" first="Ai" last="Koyanagi">Ai Koyanagi</name>
<affiliation>
<nlm:aff id="aff1">Research and Development Unit, Parc Sanitari Sant Joan de Déu, Fundació Sant Joan de Déu, Sant Boi de Llobregat, Barcelona, Spain</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff2">The Stockholm Centre for Health and Social Change (SCOHOST), Södertörn University, Huddinge, Sweden</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff3">Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Stickley, Andrew" sort="Stickley, Andrew" uniqKey="Stickley A" first="Andrew" last="Stickley">Andrew Stickley</name>
<affiliation>
<nlm:aff id="aff2">The Stockholm Centre for Health and Social Change (SCOHOST), Södertörn University, Huddinge, Sweden</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff4">Department of Human Ecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff5">Department of Child and Adolescent Mental Health, National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">PMC</idno>
<idno type="pmid">26085291</idno>
<idno type="pmc">4667394</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667394</idno>
<idno type="RBID">PMC:4667394</idno>
<idno type="doi">10.5665/sleep.5232</idno>
<date when="2015">2015</date>
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<analytic>
<title xml:lang="en" level="a" type="main">The Association between Sleep Problems and Psychotic Symptoms in the General Population: A Global Perspective</title>
<author>
<name sortKey="Koyanagi, Ai" sort="Koyanagi, Ai" uniqKey="Koyanagi A" first="Ai" last="Koyanagi">Ai Koyanagi</name>
<affiliation>
<nlm:aff id="aff1">Research and Development Unit, Parc Sanitari Sant Joan de Déu, Fundació Sant Joan de Déu, Sant Boi de Llobregat, Barcelona, Spain</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff2">The Stockholm Centre for Health and Social Change (SCOHOST), Södertörn University, Huddinge, Sweden</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff3">Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Stickley, Andrew" sort="Stickley, Andrew" uniqKey="Stickley A" first="Andrew" last="Stickley">Andrew Stickley</name>
<affiliation>
<nlm:aff id="aff2">The Stockholm Centre for Health and Social Change (SCOHOST), Södertörn University, Huddinge, Sweden</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff4">Department of Human Ecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff5">Department of Child and Adolescent Mental Health, National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan</nlm:aff>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Sleep</title>
<idno type="ISSN">0161-8105</idno>
<idno type="eISSN">1550-9109</idno>
<imprint>
<date when="2015">2015</date>
</imprint>
</series>
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<textClass></textClass>
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</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<sec>
<title>Study Objectives:</title>
<p>To assess the prevalence of sleep problems and their association with psychotic symptoms using a global database.</p>
</sec>
<sec>
<title>Design:</title>
<p>Community-based cross-sectional study.</p>
</sec>
<sec>
<title>Setting:</title>
<p>Data were analyzed from the World Health Organization's World Health Survey (WHS), a population-based survey conducted in 70 countries between 2002 and 2004.</p>
</sec>
<sec>
<title>Patients or Participants:</title>
<p>261,547 individuals aged ≥ 18 years from 56 countries.</p>
</sec>
<sec>
<title>Interventions:</title>
<p>N/A.</p>
</sec>
<sec>
<title>Measurements and Results:</title>
<p>The presence of psychotic symptoms in the past 12 months was established using 4 questions pertaining to positive symptoms from the psychosis screening module of the Composite International Diagnostic Interview. Sleep problems referred to severe or extreme sleep problems in the past 30 days. Multivariable logistic regression was used to estimate the associations. The overall prevalence of sleep problems was 7.6% and ranged from 1.6% (China) to 18.6% (Morocco). Sleep problems were associated with significantly higher odds for at least one psychotic symptom in the vast majority of countries. In the pooled sample, after adjusting for demographic factors, alcohol consumption, smoking, and chronic medical conditions, having sleep problems resulted in an odds ratio (OR) for at least one psychotic symptom of 2.41 (95% confidence interval [CI] 2.18–2.65). This OR was 1.59 (1.40–1.81) when further adjusted for anxiety and depression.</p>
</sec>
<sec>
<title>Conclusions:</title>
<p>A strong association between sleep problems and psychotic symptoms was observed globally. These results have clinical implications and serve as a basis for future studies to elucidate the causal association between psychotic symptoms and sleep problems.</p>
</sec>
<sec>
<title>Citation:</title>
<p>Koyanagi A, Stickley A. The association between sleep problems and psychotic symptoms in the general population: a global perspective.
<italic>SLEEP</italic>
2015;38(12):1875–1885.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="research-article">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Sleep</journal-id>
<journal-id journal-id-type="iso-abbrev">Sleep</journal-id>
<journal-id journal-id-type="publisher-id">Sleep</journal-id>
<journal-title-group>
<journal-title>Sleep</journal-title>
</journal-title-group>
<issn pub-type="ppub">0161-8105</issn>
<issn pub-type="epub">1550-9109</issn>
<publisher>
<publisher-name>Associated Professional Sleep Societies, LLC</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">26085291</article-id>
<article-id pub-id-type="pmc">4667394</article-id>
<article-id pub-id-type="publisher-id">sp-00084-15</article-id>
<article-id pub-id-type="doi">10.5665/sleep.5232</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Sleep Problems and Psychotic Symptoms in the General Population</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>The Association between Sleep Problems and Psychotic Symptoms in the General Population: A Global Perspective</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Koyanagi</surname>
<given-names>Ai</given-names>
</name>
<degrees>MD, MSc, PhD</degrees>
<xref ref-type="aff" rid="aff1">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="aff3">
<sup>3</sup>
</xref>
<xref ref-type="corresp" rid="cor1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Stickley</surname>
<given-names>Andrew</given-names>
</name>
<degrees>PhD</degrees>
<xref ref-type="aff" rid="aff2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="aff4">
<sup>4</sup>
</xref>
<xref ref-type="aff" rid="aff5">
<sup>5</sup>
</xref>
</contrib>
<aff id="aff1">
<label>1</label>
Research and Development Unit, Parc Sanitari Sant Joan de Déu, Fundació Sant Joan de Déu, Sant Boi de Llobregat, Barcelona, Spain</aff>
<aff id="aff2">
<label>2</label>
The Stockholm Centre for Health and Social Change (SCOHOST), Södertörn University, Huddinge, Sweden</aff>
<aff id="aff3">
<label>3</label>
Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain</aff>
<aff id="aff4">
<label>4</label>
Department of Human Ecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan</aff>
<aff id="aff5">
<label>5</label>
Department of Child and Adolescent Mental Health, National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan</aff>
</contrib-group>
<author-notes>
<corresp id="cor1">Address correspondence to: Ai Koyanagi, MD, MSc, PhD,
<addr-line>Research and Development Unit, Parc Sanitari Sant Joan de Déu, Fundació Sant Joan de Déu, Dr. Antoni Pujadas, 42, Sant Boi de Llobregat, Barcelona, Spain</addr-line>
<phone>(+34)936002685</phone>
<fax>(+34)936305319</fax>
<email>a.koyanagi@pssjd.org</email>
</corresp>
</author-notes>
<pub-date pub-type="epub">
<day>1</day>
<month>12</month>
<year>2015</year>
</pub-date>
<volume>38</volume>
<issue>12</issue>
<fpage>1875</fpage>
<lpage>1885</lpage>
<history>
<date date-type="received">
<month>2</month>
<year>2015</year>
</date>
<date date-type="rev-recd">
<month>4</month>
<year>2015</year>
</date>
<date date-type="accepted">
<month>4</month>
<year>2015</year>
</date>
</history>
<permissions>
<copyright-statement>© 2015 Associated Professional Sleep Societies, LLC.</copyright-statement>
<copyright-year>2015</copyright-year>
</permissions>
<abstract>
<sec>
<title>Study Objectives:</title>
<p>To assess the prevalence of sleep problems and their association with psychotic symptoms using a global database.</p>
</sec>
<sec>
<title>Design:</title>
<p>Community-based cross-sectional study.</p>
</sec>
<sec>
<title>Setting:</title>
<p>Data were analyzed from the World Health Organization's World Health Survey (WHS), a population-based survey conducted in 70 countries between 2002 and 2004.</p>
</sec>
<sec>
<title>Patients or Participants:</title>
<p>261,547 individuals aged ≥ 18 years from 56 countries.</p>
</sec>
<sec>
<title>Interventions:</title>
<p>N/A.</p>
</sec>
<sec>
<title>Measurements and Results:</title>
<p>The presence of psychotic symptoms in the past 12 months was established using 4 questions pertaining to positive symptoms from the psychosis screening module of the Composite International Diagnostic Interview. Sleep problems referred to severe or extreme sleep problems in the past 30 days. Multivariable logistic regression was used to estimate the associations. The overall prevalence of sleep problems was 7.6% and ranged from 1.6% (China) to 18.6% (Morocco). Sleep problems were associated with significantly higher odds for at least one psychotic symptom in the vast majority of countries. In the pooled sample, after adjusting for demographic factors, alcohol consumption, smoking, and chronic medical conditions, having sleep problems resulted in an odds ratio (OR) for at least one psychotic symptom of 2.41 (95% confidence interval [CI] 2.18–2.65). This OR was 1.59 (1.40–1.81) when further adjusted for anxiety and depression.</p>
</sec>
<sec>
<title>Conclusions:</title>
<p>A strong association between sleep problems and psychotic symptoms was observed globally. These results have clinical implications and serve as a basis for future studies to elucidate the causal association between psychotic symptoms and sleep problems.</p>
</sec>
<sec>
<title>Citation:</title>
<p>Koyanagi A, Stickley A. The association between sleep problems and psychotic symptoms in the general population: a global perspective.
<italic>SLEEP</italic>
2015;38(12):1875–1885.</p>
</sec>
</abstract>
<kwd-group>
<kwd>low- and middle-income countries</kwd>
<kwd>psychotic experience</kwd>
<kwd>sleep disturbance</kwd>
<kwd>multi-country</kwd>
<kwd>population-based</kwd>
<kwd>prevalence</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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