Oro-facial granulomatosis--a clinical and pathological analysis.
Identifieur interne : 006866 ( PubMed/Curation ); précédent : 006865; suivant : 006867Oro-facial granulomatosis--a clinical and pathological analysis.
Auteurs : D. Wiesenfeld ; M M Ferguson ; D N Mitchell ; D G Macdonald ; C. Scully ; K. Cochran ; R I RussellSource :
- The Quarterly journal of medicine [ 0033-5622 ] ; 1985.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Enfant, Enfant d'âge préscolaire, Face (anatomopathologie), Femelle, Granulome (), Granulome (anatomopathologie), Granulome à cellules géantes (anatomopathologie), Humains, Joue, Maladie de Crohn (), Maladies de la bouche (), Maladies de la bouche (anatomopathologie), Maladies de la gencive (anatomopathologie), Maladies de la lèvre (anatomopathologie), Muqueuse de la bouche (anatomopathologie), Mâle, Sarcoïdose (), Tests hématologiques.
- MESH :
- anatomopathologie : Face, Granulome, Granulome à cellules géantes, Maladies de la bouche, Maladies de la gencive, Maladies de la lèvre, Muqueuse de la bouche.
- Adolescent, Adulte, Adulte d'âge moyen, Enfant, Enfant d'âge préscolaire, Femelle, Granulome, Humains, Joue, Maladie de Crohn, Maladies de la bouche, Mâle, Sarcoïdose, Tests hématologiques.
English descriptors
- KwdEn :
- Adolescent, Adult, Cheek, Child, Child, Preschool, Crohn Disease (complications), Face (pathology), Female, Gingival Diseases (pathology), Granuloma (complications), Granuloma (pathology), Granuloma, Giant Cell (pathology), Hematologic Tests, Humans, Lip Diseases (pathology), Male, Middle Aged, Mouth Diseases (complications), Mouth Diseases (pathology), Mouth Mucosa (pathology), Sarcoidosis (complications).
- MESH :
- complications : Crohn Disease, Granuloma, Mouth Diseases, Sarcoidosis.
- pathology : Face, Gingival Diseases, Granuloma, Granuloma, Giant Cell, Lip Diseases, Mouth Diseases, Mouth Mucosa.
- Adolescent, Adult, Cheek, Child, Child, Preschool, Female, Hematologic Tests, Humans, Male, Middle Aged.
Abstract
A study of 60 patients with oro-facial granulomatosis has been conducted and the clinical presentation of this disorder defined. It encompasses the previously recognised clinical entities of Melkersson-Rosenthal syndrome and cheilitis granulomatosa. The pathological features of the disease are lymphoedema and the presence of multiple non-caseating giant cell granulomata. These granulomata are histologically indistinguishable from those found in both gastrointestinal Crohn's disease and systemic sarcoidosis. Within this series of patients, nine had evidence suggestive of gastrointestinal Crohn's disease, and in six this was confirmed. A diagnosis of sarcoidosis was made in a further two patients. The relationship of oro-facial granulomatosis to these systemic granulomatous diseases is not yet clear. Patients with oro-facial granulomatosis who have gastrointestinal symptoms should be investigated for the presence of gastrointestinal Crohn's disease. Those without symptoms should be investigated for evidence of malabsorption or serological evidence of Crohn's disease. Within the present study, the erythrocyte sedimentation rate, full blood count, corrected whole blood folate, serum albumin and calcium were the most sensitive markers of gastrointestinal involvement. Sarcoidosis should be considered in all patients with oro-facial granulomatosis. The absence of clinical signs suggestive of sarcoidosis, a normal chest radiograph and normal levels of serum angiotensin-converting enzyme makes sarcoidosis unlikely.
PubMed: 3975343
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Cochran</name></author><author><name sortKey="Russell, R I" sort="Russell, R I" uniqKey="Russell R" first="R I" last="Russell">R I Russell</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1985">1985</date><idno type="RBID">pubmed:3975343</idno><idno type="pmid">3975343</idno><idno type="wicri:Area/PubMed/Corpus">006866</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">006866</idno><idno type="wicri:Area/PubMed/Curation">006866</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">006866</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Oro-facial granulomatosis--a clinical and pathological analysis.</title><author><name sortKey="Wiesenfeld, D" sort="Wiesenfeld, D" uniqKey="Wiesenfeld D" first="D" last="Wiesenfeld">D. Wiesenfeld</name></author><author><name sortKey="Ferguson, M M" sort="Ferguson, M M" uniqKey="Ferguson M" first="M M" last="Ferguson">M M Ferguson</name></author><author><name sortKey="Mitchell, D N" sort="Mitchell, D N" uniqKey="Mitchell D" first="D N" last="Mitchell">D N Mitchell</name></author><author><name sortKey="Macdonald, D G" sort="Macdonald, D G" uniqKey="Macdonald D" first="D G" last="Macdonald">D G Macdonald</name></author><author><name sortKey="Scully, C" sort="Scully, C" uniqKey="Scully C" first="C" last="Scully">C. Scully</name></author><author><name sortKey="Cochran, K" sort="Cochran, K" uniqKey="Cochran K" first="K" last="Cochran">K. Cochran</name></author><author><name sortKey="Russell, R I" sort="Russell, R I" uniqKey="Russell R" first="R I" last="Russell">R I Russell</name></author></analytic><series><title level="j">The Quarterly journal of medicine</title><idno type="ISSN">0033-5622</idno><imprint><date when="1985" type="published">1985</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Cheek</term><term>Child</term><term>Child, Preschool</term><term>Crohn Disease (complications)</term><term>Face (pathology)</term><term>Female</term><term>Gingival Diseases (pathology)</term><term>Granuloma (complications)</term><term>Granuloma (pathology)</term><term>Granuloma, Giant Cell (pathology)</term><term>Hematologic Tests</term><term>Humans</term><term>Lip Diseases (pathology)</term><term>Male</term><term>Middle Aged</term><term>Mouth Diseases (complications)</term><term>Mouth Diseases (pathology)</term><term>Mouth Mucosa (pathology)</term><term>Sarcoidosis (complications)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Face (anatomopathologie)</term><term>Femelle</term><term>Granulome ()</term><term>Granulome (anatomopathologie)</term><term>Granulome à cellules géantes (anatomopathologie)</term><term>Humains</term><term>Joue</term><term>Maladie de Crohn ()</term><term>Maladies de la bouche ()</term><term>Maladies de la bouche (anatomopathologie)</term><term>Maladies de la gencive (anatomopathologie)</term><term>Maladies de la lèvre (anatomopathologie)</term><term>Muqueuse de la bouche (anatomopathologie)</term><term>Mâle</term><term>Sarcoïdose ()</term><term>Tests hématologiques</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Face</term><term>Granulome</term><term>Granulome à cellules géantes</term><term>Maladies de la bouche</term><term>Maladies de la gencive</term><term>Maladies de la lèvre</term><term>Muqueuse de la bouche</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Crohn Disease</term><term>Granuloma</term><term>Mouth Diseases</term><term>Sarcoidosis</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Face</term><term>Gingival Diseases</term><term>Granuloma</term><term>Granuloma, Giant Cell</term><term>Lip Diseases</term><term>Mouth Diseases</term><term>Mouth Mucosa</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Cheek</term><term>Child</term><term>Child, Preschool</term><term>Female</term><term>Hematologic Tests</term><term>Humans</term><term>Male</term><term>Middle Aged</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Femelle</term><term>Granulome</term><term>Humains</term><term>Joue</term><term>Maladie de Crohn</term><term>Maladies de la bouche</term><term>Mâle</term><term>Sarcoïdose</term><term>Tests hématologiques</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A study of 60 patients with oro-facial granulomatosis has been conducted and the clinical presentation of this disorder defined. It encompasses the previously recognised clinical entities of Melkersson-Rosenthal syndrome and cheilitis granulomatosa. The pathological features of the disease are lymphoedema and the presence of multiple non-caseating giant cell granulomata. These granulomata are histologically indistinguishable from those found in both gastrointestinal Crohn's disease and systemic sarcoidosis. Within this series of patients, nine had evidence suggestive of gastrointestinal Crohn's disease, and in six this was confirmed. A diagnosis of sarcoidosis was made in a further two patients. The relationship of oro-facial granulomatosis to these systemic granulomatous diseases is not yet clear. Patients with oro-facial granulomatosis who have gastrointestinal symptoms should be investigated for the presence of gastrointestinal Crohn's disease. Those without symptoms should be investigated for evidence of malabsorption or serological evidence of Crohn's disease. Within the present study, the erythrocyte sedimentation rate, full blood count, corrected whole blood folate, serum albumin and calcium were the most sensitive markers of gastrointestinal involvement. Sarcoidosis should be considered in all patients with oro-facial granulomatosis. The absence of clinical signs suggestive of sarcoidosis, a normal chest radiograph and normal levels of serum angiotensin-converting enzyme makes sarcoidosis unlikely.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">3975343</PMID><DateCreated><Year>1985</Year><Month>04</Month><Day>09</Day></DateCreated><DateCompleted><Year>1985</Year><Month>04</Month><Day>09</Day></DateCompleted><DateRevised><Year>2004</Year><Month>11</Month><Day>17</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0033-5622</ISSN><JournalIssue CitedMedium="Print"><Volume>54</Volume><Issue>213</Issue><PubDate><Year>1985</Year><Month>Jan</Month></PubDate></JournalIssue><Title>The Quarterly journal of medicine</Title><ISOAbbreviation>Q. J. Med.</ISOAbbreviation></Journal><ArticleTitle>Oro-facial granulomatosis--a clinical and pathological analysis.</ArticleTitle><Pagination><MedlinePgn>101-13</MedlinePgn></Pagination><Abstract><AbstractText>A study of 60 patients with oro-facial granulomatosis has been conducted and the clinical presentation of this disorder defined. It encompasses the previously recognised clinical entities of Melkersson-Rosenthal syndrome and cheilitis granulomatosa. The pathological features of the disease are lymphoedema and the presence of multiple non-caseating giant cell granulomata. These granulomata are histologically indistinguishable from those found in both gastrointestinal Crohn's disease and systemic sarcoidosis. Within this series of patients, nine had evidence suggestive of gastrointestinal Crohn's disease, and in six this was confirmed. A diagnosis of sarcoidosis was made in a further two patients. The relationship of oro-facial granulomatosis to these systemic granulomatous diseases is not yet clear. Patients with oro-facial granulomatosis who have gastrointestinal symptoms should be investigated for the presence of gastrointestinal Crohn's disease. Those without symptoms should be investigated for evidence of malabsorption or serological evidence of Crohn's disease. Within the present study, the erythrocyte sedimentation rate, full blood count, corrected whole blood folate, serum albumin and calcium were the most sensitive markers of gastrointestinal involvement. Sarcoidosis should be considered in all patients with oro-facial granulomatosis. The absence of clinical signs suggestive of sarcoidosis, a normal chest radiograph and normal levels of serum angiotensin-converting enzyme makes sarcoidosis unlikely.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Wiesenfeld</LastName><ForeName>D</ForeName><Initials>D</Initials></Author><Author ValidYN="Y"><LastName>Ferguson</LastName><ForeName>M M</ForeName><Initials>MM</Initials></Author><Author ValidYN="Y"><LastName>Mitchell</LastName><ForeName>D N</ForeName><Initials>DN</Initials></Author><Author ValidYN="Y"><LastName>MacDonald</LastName><ForeName>D G</ForeName><Initials>DG</Initials></Author><Author ValidYN="Y"><LastName>Scully</LastName><ForeName>C</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Cochran</LastName><ForeName>K</ForeName><Initials>K</Initials></Author><Author ValidYN="Y"><LastName>Russell</LastName><ForeName>R I</ForeName><Initials>RI</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Q J Med</MedlineTA><NlmUniqueID>0401027</NlmUniqueID><ISSNLinking>0033-5622</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002610" MajorTopicYN="N">Cheek</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002675" MajorTopicYN="N">Child, Preschool</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003424" MajorTopicYN="N">Crohn Disease</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005145" MajorTopicYN="N">Face</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005882" MajorTopicYN="N">Gingival Diseases</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006099" MajorTopicYN="N">Granuloma</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006101" MajorTopicYN="N">Granuloma, Giant Cell</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006403" MajorTopicYN="N">Hematologic Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008047" MajorTopicYN="N">Lip Diseases</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009059" MajorTopicYN="N">Mouth Diseases</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009061" MajorTopicYN="N">Mouth Mucosa</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012507" MajorTopicYN="N">Sarcoidosis</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1985</Year><Month>1</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1985</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1985</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">3975343</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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