Application of immunoassay methods in the serodiagnosis of human filariasis.
Identifieur interne : 006725 ( PubMed/Curation ); précédent : 006724; suivant : 006726Application of immunoassay methods in the serodiagnosis of human filariasis.
Auteurs : R G HamiltonSource :
- Reviews of infectious diseases [ 0162-0886 ]
Descripteurs français
- KwdFr :
- Anticorps (analyse), Antigènes d'helminthe (analyse), Brugia (immunologie), Complexe antigène-anticorps, Dosage radioimmunologique, Filariose lymphatique (diagnostic), Filariose lymphatique (immunologie), Humains, Indium, Lymphoedème (diagnostic), Onchocerca (immunologie), Précipitation chimique, Techniques immunoenzymatiques, Tests sérologiques.
- MESH :
- analyse : Anticorps, Antigènes d'helminthe.
- diagnostic : Filariose lymphatique, Lymphoedème.
- immunologie : Brugia, Filariose lymphatique, Onchocerca.
- Complexe antigène-anticorps, Dosage radioimmunologique, Humains, Indium, Précipitation chimique, Techniques immunoenzymatiques, Tests sérologiques.
English descriptors
- KwdEn :
- Antibodies (analysis), Antigen-Antibody Complex, Antigens, Helminth (analysis), Brugia (immunology), Chemical Precipitation, Elephantiasis, Filarial (diagnosis), Elephantiasis, Filarial (immunology), Humans, Immunoenzyme Techniques, Indium, Lymphedema (diagnosis), Onchocerca (immunology), Radioimmunoassay, Serologic Tests.
- MESH :
- chemical , analysis : Antibodies, Antigens, Helminth.
- chemical : Antigen-Antibody Complex, Indium.
- diagnosis : Elephantiasis, Filarial, Lymphedema.
- immunology : Brugia, Elephantiasis, Filarial, Onchocerca.
- Chemical Precipitation, Humans, Immunoenzyme Techniques, Radioimmunoassay, Serologic Tests.
Abstract
To be more definitive as a serodiagnostic method, an ideal immunoassay for detection of filaria-specific antibody and filarial antigens in body fluids should identify active filarial infection and differentiate between past and present infection. It should perform well in the areas of precision, reproducibility, parallelism, and sensitivity and should use reference and quality control reagents prepared with human body fluids that contain defined amounts of filarial antigen. Moreover, a sufficient quantity of reference serum in stable form should be made available to permit interlaboratory cross-standardization. Difficulty with uniform radiolabeling of filarial antigen extracts and the interference of human antibody have combined to eliminate the competitive-binding immunoassay as a useful method. Of the noncompetitive methods evaluated, the immunoradiometric assay (IRMA) and its nonisotopic counterpart, the immunoenzymetric assay (IEMA), perform best. As a factor masking diagnostically important antigenic determinants, the variable amount of human antibody in blood interfered with all assay designs tested. Better characterization of the antigen(s) circulating in the blood or excreted into the urine of infected individuals will improve assay specificity and sensitivity and will facilitate the preparation of antibody probes more specifically targeted to filarial antigens for use in both the IRMA and IEMA.
PubMed: 3906832
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :006725
Links to Exploration step
pubmed:3906832Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Application of immunoassay methods in the serodiagnosis of human filariasis.</title><author><name sortKey="Hamilton, R G" sort="Hamilton, R G" uniqKey="Hamilton R" first="R G" last="Hamilton">R G Hamilton</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="????"><PubDate><MedlineDate>1985 Nov-Dec</MedlineDate></PubDate></date><idno type="RBID">pubmed:3906832</idno><idno type="pmid">3906832</idno><idno type="wicri:Area/PubMed/Corpus">006725</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">006725</idno><idno type="wicri:Area/PubMed/Curation">006725</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">006725</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Application of immunoassay methods in the serodiagnosis of human filariasis.</title><author><name sortKey="Hamilton, R G" sort="Hamilton, R G" uniqKey="Hamilton R" first="R G" last="Hamilton">R G Hamilton</name></author></analytic><series><title level="j">Reviews of infectious diseases</title><idno type="ISSN">0162-0886</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antibodies (analysis)</term><term>Antigen-Antibody Complex</term><term>Antigens, Helminth (analysis)</term><term>Brugia (immunology)</term><term>Chemical Precipitation</term><term>Elephantiasis, Filarial (diagnosis)</term><term>Elephantiasis, Filarial (immunology)</term><term>Humans</term><term>Immunoenzyme Techniques</term><term>Indium</term><term>Lymphedema (diagnosis)</term><term>Onchocerca (immunology)</term><term>Radioimmunoassay</term><term>Serologic Tests</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Anticorps (analyse)</term><term>Antigènes d'helminthe (analyse)</term><term>Brugia (immunologie)</term><term>Complexe antigène-anticorps</term><term>Dosage radioimmunologique</term><term>Filariose lymphatique (diagnostic)</term><term>Filariose lymphatique (immunologie)</term><term>Humains</term><term>Indium</term><term>Lymphoedème (diagnostic)</term><term>Onchocerca (immunologie)</term><term>Précipitation chimique</term><term>Techniques immunoenzymatiques</term><term>Tests sérologiques</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Antibodies</term><term>Antigens, Helminth</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Antigen-Antibody Complex</term><term>Indium</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Anticorps</term><term>Antigènes d'helminthe</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Elephantiasis, Filarial</term><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Filariose lymphatique</term><term>Lymphoedème</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Brugia</term><term>Filariose lymphatique</term><term>Onchocerca</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Brugia</term><term>Elephantiasis, Filarial</term><term>Onchocerca</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Chemical Precipitation</term><term>Humans</term><term>Immunoenzyme Techniques</term><term>Radioimmunoassay</term><term>Serologic Tests</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Complexe antigène-anticorps</term><term>Dosage radioimmunologique</term><term>Humains</term><term>Indium</term><term>Précipitation chimique</term><term>Techniques immunoenzymatiques</term><term>Tests sérologiques</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To be more definitive as a serodiagnostic method, an ideal immunoassay for detection of filaria-specific antibody and filarial antigens in body fluids should identify active filarial infection and differentiate between past and present infection. It should perform well in the areas of precision, reproducibility, parallelism, and sensitivity and should use reference and quality control reagents prepared with human body fluids that contain defined amounts of filarial antigen. Moreover, a sufficient quantity of reference serum in stable form should be made available to permit interlaboratory cross-standardization. Difficulty with uniform radiolabeling of filarial antigen extracts and the interference of human antibody have combined to eliminate the competitive-binding immunoassay as a useful method. Of the noncompetitive methods evaluated, the immunoradiometric assay (IRMA) and its nonisotopic counterpart, the immunoenzymetric assay (IEMA), perform best. As a factor masking diagnostically important antigenic determinants, the variable amount of human antibody in blood interfered with all assay designs tested. Better characterization of the antigen(s) circulating in the blood or excreted into the urine of infected individuals will improve assay specificity and sensitivity and will facilitate the preparation of antibody probes more specifically targeted to filarial antigens for use in both the IRMA and IEMA.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">3906832</PMID><DateCreated><Year>1986</Year><Month>01</Month><Day>22</Day></DateCreated><DateCompleted><Year>1986</Year><Month>01</Month><Day>22</Day></DateCompleted><DateRevised><Year>2015</Year><Month>11</Month><Day>19</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0162-0886</ISSN><JournalIssue CitedMedium="Print"><Volume>7</Volume><Issue>6</Issue><PubDate><MedlineDate>1985 Nov-Dec</MedlineDate></PubDate></JournalIssue><Title>Reviews of infectious diseases</Title><ISOAbbreviation>Rev. Infect. Dis.</ISOAbbreviation></Journal><ArticleTitle>Application of immunoassay methods in the serodiagnosis of human filariasis.</ArticleTitle><Pagination><MedlinePgn>837-43</MedlinePgn></Pagination><Abstract><AbstractText>To be more definitive as a serodiagnostic method, an ideal immunoassay for detection of filaria-specific antibody and filarial antigens in body fluids should identify active filarial infection and differentiate between past and present infection. It should perform well in the areas of precision, reproducibility, parallelism, and sensitivity and should use reference and quality control reagents prepared with human body fluids that contain defined amounts of filarial antigen. Moreover, a sufficient quantity of reference serum in stable form should be made available to permit interlaboratory cross-standardization. Difficulty with uniform radiolabeling of filarial antigen extracts and the interference of human antibody have combined to eliminate the competitive-binding immunoassay as a useful method. Of the noncompetitive methods evaluated, the immunoradiometric assay (IRMA) and its nonisotopic counterpart, the immunoenzymetric assay (IEMA), perform best. As a factor masking diagnostically important antigenic determinants, the variable amount of human antibody in blood interfered with all assay designs tested. Better characterization of the antigen(s) circulating in the blood or excreted into the urine of infected individuals will improve assay specificity and sensitivity and will facilitate the preparation of antibody probes more specifically targeted to filarial antigens for use in both the IRMA and IEMA.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Hamilton</LastName><ForeName>R G</ForeName><Initials>RG</Initials></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>AI-11361</GrantID><Acronym>AI</Acronym><Agency>NIAID NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>AI-22367</GrantID><Acronym>AI</Acronym><Agency>NIAID NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D013487">Research Support, U.S. Gov't, P.H.S.</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Rev Infect Dis</MedlineTA><NlmUniqueID>7905878</NlmUniqueID><ISSNLinking>0162-0886</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000906">Antibodies</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000936">Antigen-Antibody Complex</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000947">Antigens, Helminth</NameOfSubstance></Chemical><Chemical><RegistryNumber>045A6V3VFX</RegistryNumber><NameOfSubstance UI="D007204">Indium</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000906" MajorTopicYN="N">Antibodies</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000936" MajorTopicYN="N">Antigen-Antibody Complex</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000947" MajorTopicYN="N">Antigens, Helminth</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002009" MajorTopicYN="N">Brugia</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011232" MajorTopicYN="N">Chemical Precipitation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004605" MajorTopicYN="N">Elephantiasis, Filarial</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007124" MajorTopicYN="N">Immunoenzyme Techniques</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007204" MajorTopicYN="N">Indium</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009854" MajorTopicYN="N">Onchocerca</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011863" MajorTopicYN="N">Radioimmunoassay</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012698" MajorTopicYN="N">Serologic Tests</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1985</Year><Month>11</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1985</Year><Month>11</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1985</Year><Month>11</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">3906832</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 006725 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 006725 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= PubMed
|étape= Curation
|type= RBID
|clé= pubmed:3906832
|texte= Application of immunoassay methods in the serodiagnosis of human filariasis.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:3906832" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |