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[Lymphangiosarcoma following mastectomy: review of the literature apropos of 2 recent cases of Stewart-Treves syndrome].

Identifieur interne : 006067 ( PubMed/Curation ); précédent : 006066; suivant : 006068

[Lymphangiosarcoma following mastectomy: review of the literature apropos of 2 recent cases of Stewart-Treves syndrome].

Auteurs : J O Defraigne ; B. Detroz ; J. Dubois

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RBID : pubmed:2655358

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Abstract

Two cases of lymphangiosarcomas which arose 4 and 14 years after a mastectomy are reported (Stewart-Treves syndrome). One of the patients was treated by shoulder disarticulation and the other by chemotherapy (using Melphalan, Cyclophosphamide and 5-fluorouracil). Disseminated metastases and deaths occurred 6 and 18 months after the onset of the lesion. Stewart-Treves syndrome occurs in approximately 0.07 to 0.45% of mastectomy. Prognosis is worse: survival at five year is fewer than 10%. Early diagnosis is mandatory. Surgical resection of the lesions and adjunctive chemotherapy seem the best treatment.

PubMed: 2655358

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J O Defraigne
<affiliation>
<nlm:affiliation>Service de chirurgie cardio-vasculaire et digestive, Centre Hospitalier Universitaire de Liège, Sart-Tilman.</nlm:affiliation>
<wicri:noCountry code="subField">Sart-Tilman</wicri:noCountry>
</affiliation>

Le document en format XML

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<name sortKey="Detroz, B" sort="Detroz, B" uniqKey="Detroz B" first="B" last="Detroz">B. Detroz</name>
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<term>Aged</term>
<term>Antineoplastic Combined Chemotherapy Protocols (therapeutic use)</term>
<term>Arm</term>
<term>Disarticulation</term>
<term>Female</term>
<term>Humans</term>
<term>Lymphedema (complications)</term>
<term>Lymphedema (etiology)</term>
<term>Lymphoma, Non-Hodgkin (drug therapy)</term>
<term>Lymphoma, Non-Hodgkin (etiology)</term>
<term>Lymphoma, Non-Hodgkin (surgery)</term>
<term>Mastectomy, Radical (adverse effects)</term>
<term>Soft Tissue Neoplasms (drug therapy)</term>
<term>Soft Tissue Neoplasms (etiology)</term>
<term>Soft Tissue Neoplasms (surgery)</term>
<term>Syndrome</term>
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<term>Bras</term>
<term>Désarticulation</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lymphoedème ()</term>
<term>Lymphoedème (étiologie)</term>
<term>Lymphome malin non hodgkinien ()</term>
<term>Lymphome malin non hodgkinien (traitement médicamenteux)</term>
<term>Lymphome malin non hodgkinien (étiologie)</term>
<term>Mastectomie radicale (effets indésirables)</term>
<term>Protocoles de polychimiothérapie antinéoplasique (usage thérapeutique)</term>
<term>Sujet âgé</term>
<term>Syndrome</term>
<term>Tumeurs des tissus mous ()</term>
<term>Tumeurs des tissus mous (traitement médicamenteux)</term>
<term>Tumeurs des tissus mous (étiologie)</term>
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<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en">
<term>Mastectomy, Radical</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en">
<term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en">
<term>Lymphoma, Non-Hodgkin</term>
<term>Soft Tissue Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr">
<term>Mastectomie radicale</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en">
<term>Lymphedema</term>
<term>Lymphoma, Non-Hodgkin</term>
<term>Soft Tissue Neoplasms</term>
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<term>Lymphoma, Non-Hodgkin</term>
<term>Soft Tissue Neoplasms</term>
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<term>Antineoplastic Combined Chemotherapy Protocols</term>
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<term>Lymphome malin non hodgkinien</term>
<term>Tumeurs des tissus mous</term>
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<term>Bras</term>
<term>Désarticulation</term>
<term>Femelle</term>
<term>Humains</term>
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<term>Lymphome malin non hodgkinien</term>
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<front>
<div type="abstract" xml:lang="en">Two cases of lymphangiosarcomas which arose 4 and 14 years after a mastectomy are reported (Stewart-Treves syndrome). One of the patients was treated by shoulder disarticulation and the other by chemotherapy (using Melphalan, Cyclophosphamide and 5-fluorouracil). Disseminated metastases and deaths occurred 6 and 18 months after the onset of the lesion. Stewart-Treves syndrome occurs in approximately 0.07 to 0.45% of mastectomy. Prognosis is worse: survival at five year is fewer than 10%. Early diagnosis is mandatory. Surgical resection of the lesions and adjunctive chemotherapy seem the best treatment.</div>
</front>
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<Title>Acta chirurgica Belgica</Title>
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<AbstractText>Two cases of lymphangiosarcomas which arose 4 and 14 years after a mastectomy are reported (Stewart-Treves syndrome). One of the patients was treated by shoulder disarticulation and the other by chemotherapy (using Melphalan, Cyclophosphamide and 5-fluorouracil). Disseminated metastases and deaths occurred 6 and 18 months after the onset of the lesion. Stewart-Treves syndrome occurs in approximately 0.07 to 0.45% of mastectomy. Prognosis is worse: survival at five year is fewer than 10%. Early diagnosis is mandatory. Surgical resection of the lesions and adjunctive chemotherapy seem the best treatment.</AbstractText>
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