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Creation of distal canine limb lymphedema.

Identifieur interne : 005F83 ( PubMed/Curation ); précédent : 005F82; suivant : 005F84

Creation of distal canine limb lymphedema.

Auteurs : H C Chen [Australie] ; J J Pribaz ; B M O'Brien ; K R Knight ; W A Morrison

Source :

RBID : pubmed:2727149

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English descriptors

Abstract

A canine model of distal limb lymphedema was established in order to study the treatment of this condition by lymph node transfer. This model was more difficult to establish than whole-limb lymphedema. Significant edema was achieved by a combination of preoperative irradiation and circumferential removal of skin from the irradiated areas followed by removal of the contents of the popliteal fossa. Despite these measures, it was not possible to produce lymphedema in every case, possibly because of the presence of lymphaticovenous shunts and panvascular compensation mechanisms.

PubMed: 2727149

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pubmed:2727149

Le document en format XML

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<name sortKey="Chen, H C" sort="Chen, H C" uniqKey="Chen H" first="H C" last="Chen">H C Chen</name>
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<name sortKey="O Brien, B M" sort="O Brien, B M" uniqKey="O Brien B" first="B M" last="O'Brien">B M O'Brien</name>
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<name sortKey="Knight, K R" sort="Knight, K R" uniqKey="Knight K" first="K R" last="Knight">K R Knight</name>
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<name sortKey="Morrison, W A" sort="Morrison, W A" uniqKey="Morrison W" first="W A" last="Morrison">W A Morrison</name>
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<term>Animaux</term>
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<div type="abstract" xml:lang="en">A canine model of distal limb lymphedema was established in order to study the treatment of this condition by lymph node transfer. This model was more difficult to establish than whole-limb lymphedema. Significant edema was achieved by a combination of preoperative irradiation and circumferential removal of skin from the irradiated areas followed by removal of the contents of the popliteal fossa. Despite these measures, it was not possible to produce lymphedema in every case, possibly because of the presence of lymphaticovenous shunts and panvascular compensation mechanisms.</div>
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