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Use of autologous interposition vein graft in management of lymphedema: preliminary experimental and clinical observations.

Identifieur interne : 005B38 ( PubMed/Curation ); précédent : 005B37; suivant : 005B39

Use of autologous interposition vein graft in management of lymphedema: preliminary experimental and clinical observations.

Auteurs : C. Campisi [Italie]

Source :

Lymphology [ 0024-7766 ] ; 1991.

RBID : pubmed:1921479

Descripteurs français

KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Anastomose chirurgicale, Animaux, Enfant, Femelle, Humains, Lapins, Lymphoedème (), Maladie chronique, Microscopie électronique à balayage, Mâle, Rats, Système lymphatique (), Transplantation autologue, Veines (transplantation), Études de suivi.
MESH :
- Adolescent, Adulte, Adulte d'âge moyen, Anastomose chirurgicale, Animaux, Enfant, Femelle, Humains, Lapins, Lymphoedème, Maladie chronique, Microscopie électronique à balayage, Mâle, Rats, Système lymphatique, Transplantation autologue, Veines, Études de suivi.

English descriptors

KwdEn :
- Adolescent, Adult, Anastomosis, Surgical, Animals, Child, Chronic Disease, Female, Follow-Up Studies, Humans, Lymphatic System (surgery), Lymphedema (surgery), Male, Microscopy, Electron, Scanning, Middle Aged, Rabbits, Rats, Transplantation, Autologous, Veins (transplantation).
MESH :
- surgery : Lymphatic System, Lymphedema.
- transplantation : Veins.
- Adolescent, Adult, Anastomosis, Surgical, Animals, Child, Chronic Disease, Female, Follow-Up Studies, Humans, Male, Microscopy, Electron, Scanning, Middle Aged, Rabbits, Rats, Transplantation, Autologous.

Abstract

We report preliminary experimental studies in rats and rabbits together with clinical observations in 39 patients with chronic lymphedema undergoing interposition autologous lymphatic-venous-lymphatic (LVL) anastomoses. This microsurgical operative technique is an alternative to other lymphatic shunting methods particularly where venous disease coexists in the same limb and where direct lymphatic-venous bypass is accordingly inappropriate. Preoperative diagnostic evaluation including lymphatic and venous isotopic scintigraphy, Doppler venous flow metrics and pressure manometry play an essential role in delineating the status of both the lymphatic and venous systems and in determining which microsurgical procedure, if any, is indicated. Our microsurgical method consists of inserting suitably large and lengthy autologous venous grafts between lymphatic collectors above and below the site of blockage to lymph flow. The data demonstrate the feasibility of the LVL technique experimentally and in 39 patients with obstructive lymphedema (either arm or leg). Using LVL shunt, improvement was seen in both limb function and edema, and in some, edema regression was permanent for as long as 5 years.

PubMed: 1921479

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Le document en format XML

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<term>Chronic Disease</term>
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<term>Animaux</term>
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<term>Lymphoedème ()</term>
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<term>Microscopie électronique à balayage</term>
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<term>Transplantation autologue</term>
<term>Veines (transplantation)</term>
<term>Études de suivi</term>
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<term>Anastomosis, Surgical</term>
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<term>Chronic Disease</term>
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<term>Animaux</term>
<term>Enfant</term>
<term>Femelle</term>
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<term>Lapins</term>
<term>Lymphoedème</term>
<term>Maladie chronique</term>
<term>Microscopie électronique à balayage</term>
<term>Mâle</term>
<term>Rats</term>
<term>Système lymphatique</term>
<term>Transplantation autologue</term>
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<term>Études de suivi</term>
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<front><div type="abstract" xml:lang="en">We report preliminary experimental studies in rats and rabbits together with clinical observations in 39 patients with chronic lymphedema undergoing interposition autologous lymphatic-venous-lymphatic (LVL) anastomoses. This microsurgical operative technique is an alternative to other lymphatic shunting methods particularly where venous disease coexists in the same limb and where direct lymphatic-venous bypass is accordingly inappropriate. Preoperative diagnostic evaluation including lymphatic and venous isotopic scintigraphy, Doppler venous flow metrics and pressure manometry play an essential role in delineating the status of both the lymphatic and venous systems and in determining which microsurgical procedure, if any, is indicated. Our microsurgical method consists of inserting suitably large and lengthy autologous venous grafts between lymphatic collectors above and below the site of blockage to lymph flow. The data demonstrate the feasibility of the LVL technique experimentally and in 39 patients with obstructive lymphedema (either arm or leg). Using LVL shunt, improvement was seen in both limb function and edema, and in some, edema regression was permanent for as long as 5 years.</div>
</front>
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<Abstract><AbstractText>We report preliminary experimental studies in rats and rabbits together with clinical observations in 39 patients with chronic lymphedema undergoing interposition autologous lymphatic-venous-lymphatic (LVL) anastomoses. This microsurgical operative technique is an alternative to other lymphatic shunting methods particularly where venous disease coexists in the same limb and where direct lymphatic-venous bypass is accordingly inappropriate. Preoperative diagnostic evaluation including lymphatic and venous isotopic scintigraphy, Doppler venous flow metrics and pressure manometry play an essential role in delineating the status of both the lymphatic and venous systems and in determining which microsurgical procedure, if any, is indicated. Our microsurgical method consists of inserting suitably large and lengthy autologous venous grafts between lymphatic collectors above and below the site of blockage to lymph flow. The data demonstrate the feasibility of the LVL technique experimentally and in 39 patients with obstructive lymphedema (either arm or leg). Using LVL shunt, improvement was seen in both limb function and edema, and in some, edema regression was permanent for as long as 5 years.</AbstractText>
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Use of autologous interposition vein graft in management of lymphedema: preliminary experimental and clinical observations.

Use of autologous interposition vein graft in management of lymphedema: preliminary experimental and clinical observations.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki