Topical treatment of acute hindlimb lymphedema of the rat using a troxerutin-phosphatidylcholine complex in liposomal-like microdispersion.
Identifieur interne : 005766 ( PubMed/Curation ); précédent : 005765; suivant : 005767Topical treatment of acute hindlimb lymphedema of the rat using a troxerutin-phosphatidylcholine complex in liposomal-like microdispersion.
Auteurs : J R Casley-Smith [Australie] ; J R Casley-Smith ; S. Curri ; M. FöldiSource :
- Lymphology [ 0024-7766 ] ; 1993.
Descripteurs français
- KwdFr :
- Administration par voie topique, Animaux, Liposomes, Lymphoedème (traitement médicamenteux), Membre pelvien, O-(bêta-Hydroxyéthyl)rutosides (administration et posologie), O-(bêta-Hydroxyéthyl)rutosides (analogues et dérivés), O-(bêta-Hydroxyéthyl)rutosides (usage thérapeutique), Phosphatidylcholines (administration et posologie), Phosphatidylcholines (usage thérapeutique), Rats, Vecteurs de médicaments.
- MESH :
- administration et posologie : O-(bêta-Hydroxyéthyl)rutosides, Phosphatidylcholines.
- analogues et dérivés : O-(bêta-Hydroxyéthyl)rutosides.
- traitement médicamenteux : Lymphoedème.
- usage thérapeutique : O-(bêta-Hydroxyéthyl)rutosides, Phosphatidylcholines.
- Administration par voie topique, Animaux, Liposomes, Membre pelvien, Rats, Vecteurs de médicaments.
English descriptors
- KwdEn :
- Administration, Topical, Animals, Drug Carriers, Hindlimb, Hydroxyethylrutoside (administration & dosage), Hydroxyethylrutoside (analogs & derivatives), Hydroxyethylrutoside (therapeutic use), Liposomes, Lymphedema (drug therapy), Phosphatidylcholines (administration & dosage), Phosphatidylcholines (therapeutic use), Rats.
- MESH :
- chemical , administration & dosage : Hydroxyethylrutoside, Phosphatidylcholines.
- chemical , analogs & derivatives : Hydroxyethylrutoside.
- chemical , therapeutic use : Hydroxyethylrutoside, Phosphatidylcholines.
- chemical : Drug Carriers, Liposomes.
- drug therapy : Lymphedema.
- Administration, Topical, Animals, Hindlimb, Rats.
Abstract
A new reversible complex between troxerutin and phosphatidylcholine (85-90mg/kg per day), in the form of a liposome-like water microdispersion, was topically applied to the rat thigh in an experimental counterpart of acute lymphedema. After four days there was 75% less hindlimb edema (mean decrease 40% of normal compared to control 10% of normal) in the treated compared with the untreated rats. These findings suggest that this drug preparation may be useful to minimize acute peripheral lymphedema in patients.
PubMed: 8464222
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :005766
Links to Exploration step
pubmed:8464222Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Topical treatment of acute hindlimb lymphedema of the rat using a troxerutin-phosphatidylcholine complex in liposomal-like microdispersion.</title><author><name sortKey="Casley Smith, J R" sort="Casley Smith, J R" uniqKey="Casley Smith J" first="J R" last="Casley-Smith">J R Casley-Smith</name><affiliation wicri:level="1"><nlm:affiliation>Henry Thomas Lab, University of Adelaide, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Henry Thomas Lab, University of Adelaide</wicri:regionArea></affiliation></author><author><name sortKey="Casley Smith, J R" sort="Casley Smith, J R" uniqKey="Casley Smith J" first="J R" last="Casley-Smith">J R Casley-Smith</name></author><author><name sortKey="Curri, S" sort="Curri, S" uniqKey="Curri S" first="S" last="Curri">S. Curri</name></author><author><name sortKey="Foldi, M" sort="Foldi, M" uniqKey="Foldi M" first="M" last="Földi">M. Földi</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1993">1993</date><idno type="RBID">pubmed:8464222</idno><idno type="pmid">8464222</idno><idno type="wicri:Area/PubMed/Corpus">005766</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">005766</idno><idno type="wicri:Area/PubMed/Curation">005766</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">005766</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Topical treatment of acute hindlimb lymphedema of the rat using a troxerutin-phosphatidylcholine complex in liposomal-like microdispersion.</title><author><name sortKey="Casley Smith, J R" sort="Casley Smith, J R" uniqKey="Casley Smith J" first="J R" last="Casley-Smith">J R Casley-Smith</name><affiliation wicri:level="1"><nlm:affiliation>Henry Thomas Lab, University of Adelaide, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Henry Thomas Lab, University of Adelaide</wicri:regionArea></affiliation></author><author><name sortKey="Casley Smith, J R" sort="Casley Smith, J R" uniqKey="Casley Smith J" first="J R" last="Casley-Smith">J R Casley-Smith</name></author><author><name sortKey="Curri, S" sort="Curri, S" uniqKey="Curri S" first="S" last="Curri">S. Curri</name></author><author><name sortKey="Foldi, M" sort="Foldi, M" uniqKey="Foldi M" first="M" last="Földi">M. Földi</name></author></analytic><series><title level="j">Lymphology</title><idno type="ISSN">0024-7766</idno><imprint><date when="1993" type="published">1993</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Administration, Topical</term><term>Animals</term><term>Drug Carriers</term><term>Hindlimb</term><term>Hydroxyethylrutoside (administration & dosage)</term><term>Hydroxyethylrutoside (analogs & derivatives)</term><term>Hydroxyethylrutoside (therapeutic use)</term><term>Liposomes</term><term>Lymphedema (drug therapy)</term><term>Phosphatidylcholines (administration & dosage)</term><term>Phosphatidylcholines (therapeutic use)</term><term>Rats</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Administration par voie topique</term><term>Animaux</term><term>Liposomes</term><term>Lymphoedème (traitement médicamenteux)</term><term>Membre pelvien</term><term>O-(bêta-Hydroxyéthyl)rutosides (administration et posologie)</term><term>O-(bêta-Hydroxyéthyl)rutosides (analogues et dérivés)</term><term>O-(bêta-Hydroxyéthyl)rutosides (usage thérapeutique)</term><term>Phosphatidylcholines (administration et posologie)</term><term>Phosphatidylcholines (usage thérapeutique)</term><term>Rats</term><term>Vecteurs de médicaments</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Hydroxyethylrutoside</term><term>Phosphatidylcholines</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Hydroxyethylrutoside</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Hydroxyethylrutoside</term><term>Phosphatidylcholines</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Drug Carriers</term><term>Liposomes</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>O-(bêta-Hydroxyéthyl)rutosides</term><term>Phosphatidylcholines</term></keywords><keywords scheme="MESH" qualifier="analogues et dérivés" xml:lang="fr"><term>O-(bêta-Hydroxyéthyl)rutosides</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Lymphoedème</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>O-(bêta-Hydroxyéthyl)rutosides</term><term>Phosphatidylcholines</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Administration, Topical</term><term>Animals</term><term>Hindlimb</term><term>Rats</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Administration par voie topique</term><term>Animaux</term><term>Liposomes</term><term>Membre pelvien</term><term>Rats</term><term>Vecteurs de médicaments</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A new reversible complex between troxerutin and phosphatidylcholine (85-90mg/kg per day), in the form of a liposome-like water microdispersion, was topically applied to the rat thigh in an experimental counterpart of acute lymphedema. After four days there was 75% less hindlimb edema (mean decrease 40% of normal compared to control 10% of normal) in the treated compared with the untreated rats. These findings suggest that this drug preparation may be useful to minimize acute peripheral lymphedema in patients.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">8464222</PMID><DateCreated><Year>1993</Year><Month>05</Month><Day>06</Day></DateCreated><DateCompleted><Year>1993</Year><Month>05</Month><Day>06</Day></DateCompleted><DateRevised><Year>2012</Year><Month>11</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0024-7766</ISSN><JournalIssue CitedMedium="Print"><Volume>26</Volume><Issue>1</Issue><PubDate><Year>1993</Year><Month>Mar</Month></PubDate></JournalIssue><Title>Lymphology</Title><ISOAbbreviation>Lymphology</ISOAbbreviation></Journal><ArticleTitle>Topical treatment of acute hindlimb lymphedema of the rat using a troxerutin-phosphatidylcholine complex in liposomal-like microdispersion.</ArticleTitle><Pagination><MedlinePgn>25-7</MedlinePgn></Pagination><Abstract><AbstractText>A new reversible complex between troxerutin and phosphatidylcholine (85-90mg/kg per day), in the form of a liposome-like water microdispersion, was topically applied to the rat thigh in an experimental counterpart of acute lymphedema. After four days there was 75% less hindlimb edema (mean decrease 40% of normal compared to control 10% of normal) in the treated compared with the untreated rats. These findings suggest that this drug preparation may be useful to minimize acute peripheral lymphedema in patients.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Casley-Smith</LastName><ForeName>J R</ForeName><Initials>JR</Initials><AffiliationInfo><Affiliation>Henry Thomas Lab, University of Adelaide, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Casley-Smith</LastName><ForeName>J R</ForeName><Initials>JR</Initials></Author><Author ValidYN="Y"><LastName>Curri</LastName><ForeName>S</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Földi</LastName><ForeName>M</ForeName><Initials>M</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Lymphology</MedlineTA><NlmUniqueID>0155112</NlmUniqueID><ISSNLinking>0024-7766</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D004337">Drug Carriers</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D006896">Hydroxyethylrutoside</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D008081">Liposomes</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010713">Phosphatidylcholines</NameOfSubstance></Chemical><Chemical><RegistryNumber>7Y4N11PXO8</RegistryNumber><NameOfSubstance UI="C005865">troxerutin</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000287" MajorTopicYN="N">Administration, Topical</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004337" MajorTopicYN="N">Drug Carriers</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006614" MajorTopicYN="N">Hindlimb</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006896" MajorTopicYN="N">Hydroxyethylrutoside</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000031" MajorTopicYN="Y">analogs & derivatives</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008081" MajorTopicYN="N">Liposomes</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010713" MajorTopicYN="N">Phosphatidylcholines</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D051381" MajorTopicYN="N">Rats</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1993</Year><Month>3</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1993</Year><Month>3</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1993</Year><Month>3</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">8464222</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005766 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 005766 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= PubMed
|étape= Curation
|type= RBID
|clé= pubmed:8464222
|texte= Topical treatment of acute hindlimb lymphedema of the rat using a troxerutin-phosphatidylcholine complex in liposomal-like microdispersion.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:8464222" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |