Characterization of antibody responses to Wolbachia surface protein in humans with lymphatic filariasis.
Identifieur interne : 004189 ( PubMed/Curation ); précédent : 004188; suivant : 004190Characterization of antibody responses to Wolbachia surface protein in humans with lymphatic filariasis.
Auteurs : George A. Punkosdy [États-Unis] ; David G. Addiss ; Patrick J. LammieSource :
- Infection and immunity [ 0019-9567 ] ; 2003.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Animaux, Anticorps antibactériens (sang), Antigènes bactériens (génétique), Brugia malayi (microbiologie), Cartographie épitopique, Facteurs temps, Femelle, Filariose lymphatique (immunologie), Filariose lymphatique (microbiologie), Filariose lymphatique (parasitologie), Haïti, Humains, Hydrocèle (immunologie), Hydrocèle (microbiologie), Hydrocèle (parasitologie), Immunoglobuline G (sang), Mâle, Protéines bactériennes (génétique), Protéines bactériennes (immunologie), Protéines membranaires (génétique), Protéines membranaires (immunologie), Sujet âgé, Symbiose, Séquence d'acides aminés, Wolbachia (génétique), Wolbachia (immunologie), Wolbachia (pathogénicité), Études cas-témoins.
- MESH :
- génétique : Antigènes bactériens, Protéines bactériennes, Protéines membranaires, Wolbachia.
- immunologie : Filariose lymphatique, Hydrocèle, Protéines bactériennes, Protéines membranaires, Wolbachia.
- microbiologie : Brugia malayi, Filariose lymphatique, Hydrocèle.
- parasitologie : Filariose lymphatique, Hydrocèle.
- pathogénicité : Wolbachia.
- sang : Anticorps antibactériens, Immunoglobuline G.
- Adolescent, Adulte, Adulte d'âge moyen, Animaux, Cartographie épitopique, Facteurs temps, Femelle, Haïti, Humains, Mâle, Sujet âgé, Symbiose, Séquence d'acides aminés, Études cas-témoins.
- Wicri :
- geographic : Haïti.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Amino Acid Sequence, Animals, Antibodies, Bacterial (blood), Antigens, Bacterial (genetics), Bacterial Proteins (genetics), Bacterial Proteins (immunology), Brugia malayi (microbiology), Case-Control Studies, Elephantiasis, Filarial (immunology), Elephantiasis, Filarial (microbiology), Elephantiasis, Filarial (parasitology), Epitope Mapping, Female, Haiti, Humans, Immunoglobulin G (blood), Male, Membrane Proteins (genetics), Membrane Proteins (immunology), Middle Aged, Symbiosis, Testicular Hydrocele (immunology), Testicular Hydrocele (microbiology), Testicular Hydrocele (parasitology), Time Factors, Wolbachia (genetics), Wolbachia (immunology), Wolbachia (pathogenicity).
- MESH :
- chemical , blood : Antibodies, Bacterial, Immunoglobulin G.
- chemical , genetics : Antigens, Bacterial, Bacterial Proteins, Membrane Proteins.
- chemical , immunology : Bacterial Proteins, Membrane Proteins.
- geographic : Haiti.
- genetics : Wolbachia.
- immunology : Elephantiasis, Filarial, Testicular Hydrocele, Wolbachia.
- microbiology : Brugia malayi, Elephantiasis, Filarial, Testicular Hydrocele.
- parasitology : Elephantiasis, Filarial, Testicular Hydrocele.
- pathogenicity : Wolbachia.
- Adolescent, Adult, Aged, Amino Acid Sequence, Animals, Case-Control Studies, Epitope Mapping, Female, Humans, Male, Middle Aged, Symbiosis, Time Factors.
Abstract
Symbiotic Wolbachia organisms of filarial nematodes have received much attention as possible chemotherapy targets and disease-causing organisms. In order to further investigate the association between anti-Wolbachia immune responses and chronic filarial disease in humans, antibody responses to Wolbachia surface protein (WSP) were assayed in serum samples collected from 232 individuals living in Leogane, Haiti, an area where Wuchereria bancrofti infection is endemic, and from 67 North Americans with no history of lymphatic filariasis. As opposed to antifilarial antibody responses, which were largely influenced by the patient's infection status, the prevalence and levels of anti-WSP immunoglobulin G (IgG) antibodies among individuals with lymphedema or hydrocele were significantly greater than those in gender- and infection-matched individuals without disease. In at least one case, the anti-WSP IgG response was coincident with the onset of lymphedema development, and among anti-WSP-positive women with lymphedema, anti-WSP IgG levels were negatively correlated with the duration of lymphedema. The presence of anti-WSP IgG was also associated with the severity of inguinal adenopathy among men with hydrocele. In addition to the presence of anti-WSP antibodies among Haitians, 15 of 67 (22%) serum samples collected from individuals from North America, where filariasis is not endemic, were also positive for anti-WSP antibodies. In comparison to those from Haitians, anti-WSP antibodies from North Americans primarily recognized a distinct region of WSP located within the highly conserved second transmembrane domain. The results of this study demonstrate that anti-WSP antibody responses are associated with the presence of chronic filarial morbidity and not filarial infection status in humans and suggest that WSP should be further studied as a potential trigger for the development of filarial disease.
PubMed: 12933853
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :004189
Links to Exploration step
pubmed:12933853Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Characterization of antibody responses to Wolbachia surface protein in humans with lymphatic filariasis.</title>
<author><name sortKey="Punkosdy, George A" sort="Punkosdy, George A" uniqKey="Punkosdy G" first="George A" last="Punkosdy">George A. Punkosdy</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cellular Biology, University of Georgia, Athens, Georgia, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Cellular Biology, University of Georgia, Athens, Georgia</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Addiss, David G" sort="Addiss, David G" uniqKey="Addiss D" first="David G" last="Addiss">David G. Addiss</name>
</author>
<author><name sortKey="Lammie, Patrick J" sort="Lammie, Patrick J" uniqKey="Lammie P" first="Patrick J" last="Lammie">Patrick J. Lammie</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2003">2003</date>
<idno type="RBID">pubmed:12933853</idno>
<idno type="pmid">12933853</idno>
<idno type="wicri:Area/PubMed/Corpus">004189</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">004189</idno>
<idno type="wicri:Area/PubMed/Curation">004189</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">004189</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Characterization of antibody responses to Wolbachia surface protein in humans with lymphatic filariasis.</title>
<author><name sortKey="Punkosdy, George A" sort="Punkosdy, George A" uniqKey="Punkosdy G" first="George A" last="Punkosdy">George A. Punkosdy</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Cellular Biology, University of Georgia, Athens, Georgia, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Cellular Biology, University of Georgia, Athens, Georgia</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Addiss, David G" sort="Addiss, David G" uniqKey="Addiss D" first="David G" last="Addiss">David G. Addiss</name>
</author>
<author><name sortKey="Lammie, Patrick J" sort="Lammie, Patrick J" uniqKey="Lammie P" first="Patrick J" last="Lammie">Patrick J. Lammie</name>
</author>
</analytic>
<series><title level="j">Infection and immunity</title>
<idno type="ISSN">0019-9567</idno>
<imprint><date when="2003" type="published">2003</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Amino Acid Sequence</term>
<term>Animals</term>
<term>Antibodies, Bacterial (blood)</term>
<term>Antigens, Bacterial (genetics)</term>
<term>Bacterial Proteins (genetics)</term>
<term>Bacterial Proteins (immunology)</term>
<term>Brugia malayi (microbiology)</term>
<term>Case-Control Studies</term>
<term>Elephantiasis, Filarial (immunology)</term>
<term>Elephantiasis, Filarial (microbiology)</term>
<term>Elephantiasis, Filarial (parasitology)</term>
<term>Epitope Mapping</term>
<term>Female</term>
<term>Haiti</term>
<term>Humans</term>
<term>Immunoglobulin G (blood)</term>
<term>Male</term>
<term>Membrane Proteins (genetics)</term>
<term>Membrane Proteins (immunology)</term>
<term>Middle Aged</term>
<term>Symbiosis</term>
<term>Testicular Hydrocele (immunology)</term>
<term>Testicular Hydrocele (microbiology)</term>
<term>Testicular Hydrocele (parasitology)</term>
<term>Time Factors</term>
<term>Wolbachia (genetics)</term>
<term>Wolbachia (immunology)</term>
<term>Wolbachia (pathogenicity)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Animaux</term>
<term>Anticorps antibactériens (sang)</term>
<term>Antigènes bactériens (génétique)</term>
<term>Brugia malayi (microbiologie)</term>
<term>Cartographie épitopique</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Filariose lymphatique (immunologie)</term>
<term>Filariose lymphatique (microbiologie)</term>
<term>Filariose lymphatique (parasitologie)</term>
<term>Haïti</term>
<term>Humains</term>
<term>Hydrocèle (immunologie)</term>
<term>Hydrocèle (microbiologie)</term>
<term>Hydrocèle (parasitologie)</term>
<term>Immunoglobuline G (sang)</term>
<term>Mâle</term>
<term>Protéines bactériennes (génétique)</term>
<term>Protéines bactériennes (immunologie)</term>
<term>Protéines membranaires (génétique)</term>
<term>Protéines membranaires (immunologie)</term>
<term>Sujet âgé</term>
<term>Symbiose</term>
<term>Séquence d'acides aminés</term>
<term>Wolbachia (génétique)</term>
<term>Wolbachia (immunologie)</term>
<term>Wolbachia (pathogénicité)</term>
<term>Études cas-témoins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Bacterial</term>
<term>Immunoglobulin G</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Antigens, Bacterial</term>
<term>Bacterial Proteins</term>
<term>Membrane Proteins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Bacterial Proteins</term>
<term>Membrane Proteins</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>Haiti</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Wolbachia</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Antigènes bactériens</term>
<term>Protéines bactériennes</term>
<term>Protéines membranaires</term>
<term>Wolbachia</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Filariose lymphatique</term>
<term>Hydrocèle</term>
<term>Protéines bactériennes</term>
<term>Protéines membranaires</term>
<term>Wolbachia</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Elephantiasis, Filarial</term>
<term>Testicular Hydrocele</term>
<term>Wolbachia</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Brugia malayi</term>
<term>Filariose lymphatique</term>
<term>Hydrocèle</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Brugia malayi</term>
<term>Elephantiasis, Filarial</term>
<term>Testicular Hydrocele</term>
</keywords>
<keywords scheme="MESH" qualifier="parasitologie" xml:lang="fr"><term>Filariose lymphatique</term>
<term>Hydrocèle</term>
</keywords>
<keywords scheme="MESH" qualifier="parasitology" xml:lang="en"><term>Elephantiasis, Filarial</term>
<term>Testicular Hydrocele</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Wolbachia</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Wolbachia</term>
</keywords>
<keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Anticorps antibactériens</term>
<term>Immunoglobuline G</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Amino Acid Sequence</term>
<term>Animals</term>
<term>Case-Control Studies</term>
<term>Epitope Mapping</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Symbiosis</term>
<term>Time Factors</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Animaux</term>
<term>Cartographie épitopique</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Haïti</term>
<term>Humains</term>
<term>Mâle</term>
<term>Sujet âgé</term>
<term>Symbiose</term>
<term>Séquence d'acides aminés</term>
<term>Études cas-témoins</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Haïti</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Symbiotic Wolbachia organisms of filarial nematodes have received much attention as possible chemotherapy targets and disease-causing organisms. In order to further investigate the association between anti-Wolbachia immune responses and chronic filarial disease in humans, antibody responses to Wolbachia surface protein (WSP) were assayed in serum samples collected from 232 individuals living in Leogane, Haiti, an area where Wuchereria bancrofti infection is endemic, and from 67 North Americans with no history of lymphatic filariasis. As opposed to antifilarial antibody responses, which were largely influenced by the patient's infection status, the prevalence and levels of anti-WSP immunoglobulin G (IgG) antibodies among individuals with lymphedema or hydrocele were significantly greater than those in gender- and infection-matched individuals without disease. In at least one case, the anti-WSP IgG response was coincident with the onset of lymphedema development, and among anti-WSP-positive women with lymphedema, anti-WSP IgG levels were negatively correlated with the duration of lymphedema. The presence of anti-WSP IgG was also associated with the severity of inguinal adenopathy among men with hydrocele. In addition to the presence of anti-WSP antibodies among Haitians, 15 of 67 (22%) serum samples collected from individuals from North America, where filariasis is not endemic, were also positive for anti-WSP antibodies. In comparison to those from Haitians, anti-WSP antibodies from North Americans primarily recognized a distinct region of WSP located within the highly conserved second transmembrane domain. The results of this study demonstrate that anti-WSP antibody responses are associated with the presence of chronic filarial morbidity and not filarial infection status in humans and suggest that WSP should be further studied as a potential trigger for the development of filarial disease.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">12933853</PMID>
<DateCreated><Year>2003</Year>
<Month>08</Month>
<Day>22</Day>
</DateCreated>
<DateCompleted><Year>2003</Year>
<Month>09</Month>
<Day>29</Day>
</DateCompleted>
<DateRevised><Year>2017</Year>
<Month>02</Month>
<Day>19</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0019-9567</ISSN>
<JournalIssue CitedMedium="Print"><Volume>71</Volume>
<Issue>9</Issue>
<PubDate><Year>2003</Year>
<Month>Sep</Month>
</PubDate>
</JournalIssue>
<Title>Infection and immunity</Title>
<ISOAbbreviation>Infect. Immun.</ISOAbbreviation>
</Journal>
<ArticleTitle>Characterization of antibody responses to Wolbachia surface protein in humans with lymphatic filariasis.</ArticleTitle>
<Pagination><MedlinePgn>5104-14</MedlinePgn>
</Pagination>
<Abstract><AbstractText>Symbiotic Wolbachia organisms of filarial nematodes have received much attention as possible chemotherapy targets and disease-causing organisms. In order to further investigate the association between anti-Wolbachia immune responses and chronic filarial disease in humans, antibody responses to Wolbachia surface protein (WSP) were assayed in serum samples collected from 232 individuals living in Leogane, Haiti, an area where Wuchereria bancrofti infection is endemic, and from 67 North Americans with no history of lymphatic filariasis. As opposed to antifilarial antibody responses, which were largely influenced by the patient's infection status, the prevalence and levels of anti-WSP immunoglobulin G (IgG) antibodies among individuals with lymphedema or hydrocele were significantly greater than those in gender- and infection-matched individuals without disease. In at least one case, the anti-WSP IgG response was coincident with the onset of lymphedema development, and among anti-WSP-positive women with lymphedema, anti-WSP IgG levels were negatively correlated with the duration of lymphedema. The presence of anti-WSP IgG was also associated with the severity of inguinal adenopathy among men with hydrocele. In addition to the presence of anti-WSP antibodies among Haitians, 15 of 67 (22%) serum samples collected from individuals from North America, where filariasis is not endemic, were also positive for anti-WSP antibodies. In comparison to those from Haitians, anti-WSP antibodies from North Americans primarily recognized a distinct region of WSP located within the highly conserved second transmembrane domain. The results of this study demonstrate that anti-WSP antibody responses are associated with the presence of chronic filarial morbidity and not filarial infection status in humans and suggest that WSP should be further studied as a potential trigger for the development of filarial disease.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Punkosdy</LastName>
<ForeName>George A</ForeName>
<Initials>GA</Initials>
<AffiliationInfo><Affiliation>Department of Cellular Biology, University of Georgia, Athens, Georgia, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Addiss</LastName>
<ForeName>David G</ForeName>
<Initials>DG</Initials>
</Author>
<Author ValidYN="Y"><LastName>Lammie</LastName>
<ForeName>Patrick J</ForeName>
<Initials>PJ</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013487">Research Support, U.S. Gov't, P.H.S.</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Infect Immun</MedlineTA>
<NlmUniqueID>0246127</NlmUniqueID>
<ISSNLinking>0019-9567</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000907">Antibodies, Bacterial</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000942">Antigens, Bacterial</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D001426">Bacterial Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D007074">Immunoglobulin G</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D008565">Membrane Proteins</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Insect Mol Biol. 2000 Aug;9(4):393-405</RefSource>
<PMID Version="1">10971717</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Parasitol Today. 1998 Dec;14(6):229-34</RefSource>
<PMID Version="1">17040766</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Parasitol Today. 2000 Apr;16(4):135</RefSource>
<PMID Version="1">10725894</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Science. 2002 Mar 8;295(5561):1892-5</RefSource>
<PMID Version="1">11884755</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Clin Diagn Lab Immunol. 2003 Jan;10(1):180-1</RefSource>
<PMID Version="1">12522059</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Science. 2001 May 11;292(5519):1093-5</RefSource>
<PMID Version="1">11352061</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Trop Med Hyg. 2002 Feb;66(2):163-9</RefSource>
<PMID Version="1">12135288</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Parasitol. 2002 Jun;88(3):605-11</RefSource>
<PMID Version="1">12099435</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Lancet. 2001 May 5;357(9266):1415-6</RefSource>
<PMID Version="1">11356444</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Infect Dis. 2001 Aug 1;184(3):385-9</RefSource>
<PMID Version="1">11443570</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Int J Parasitol. 1999 Feb;29(2):357-64</RefSource>
<PMID Version="1">10221636</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trans R Soc Trop Med Hyg. 1999 Jul-Aug;93(4):413-7</RefSource>
<PMID Version="1">10674092</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Curr Microbiol. 2000 Aug;41(2):96-100</RefSource>
<PMID Version="1">10856373</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Clin Invest. 1999 Jan;103(1):11-8</RefSource>
<PMID Version="1">9884329</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Proc Biol Sci. 2000 Jul 7;267(1450):1277-85</RefSource>
<PMID Version="1">10972121</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Microbes Infect. 2000 Aug;2(10):1147-57</RefSource>
<PMID Version="1">11008105</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Infect Immun. 1996 Aug;64(8):2962-7</RefSource>
<PMID Version="1">8757821</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Proc Biol Sci. 2000 Dec 22;267(1461):2511-6</RefSource>
<PMID Version="1">11197127</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Lancet. 2000 Apr 8;355(9211):1242-3</RefSource>
<PMID Version="1">10770311</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Parasitol. 1993 Oct;79(5):775-7</RefSource>
<PMID Version="1">8410553</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Infect Dis. 2002 Mar 15;185(6):805-11</RefSource>
<PMID Version="1">11920298</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Proc Biol Sci. 2000 Jun 7;267(1448):1063-9</RefSource>
<PMID Version="1">10885510</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Mol Biol Evol. 2002 Aug;19(8):1341-9</RefSource>
<PMID Version="1">12140246</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Exp Med. 2000 Apr 17;191(8):1429-36</RefSource>
<PMID Version="1">10770808</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Parasitol Today. 2000 Dec;16(12):544-8</RefSource>
<PMID Version="1">11121854</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Infect Dis. 1995 Mar;171(3):755-8</RefSource>
<PMID Version="1">7876636</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Bacteriol. 1998 May;180(9):2373-8</RefSource>
<PMID Version="1">9573188</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Ann N Y Acad Sci. 2002 Dec;979:131-42; discussion 188-96</RefSource>
<PMID Version="1">12543723</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Trop Med Hyg. 1991 Feb;44(2):161-7</RefSource>
<PMID Version="1">2012259</PMID>
</CommentsCorrections>
</CommentsCorrectionsList>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000595" MajorTopicYN="N">Amino Acid Sequence</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000907" MajorTopicYN="N">Antibodies, Bacterial</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000942" MajorTopicYN="N">Antigens, Bacterial</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001426" MajorTopicYN="N">Bacterial Proteins</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017178" MajorTopicYN="N">Brugia malayi</DescriptorName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016022" MajorTopicYN="N">Case-Control Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004605" MajorTopicYN="N">Elephantiasis, Filarial</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="Y">microbiology</QualifierName>
<QualifierName UI="Q000469" MajorTopicYN="N">parasitology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018604" MajorTopicYN="N">Epitope Mapping</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006205" MajorTopicYN="N" Type="Geographic">Haiti</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007074" MajorTopicYN="N">Immunoglobulin G</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008565" MajorTopicYN="N">Membrane Proteins</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013559" MajorTopicYN="N">Symbiosis</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006848" MajorTopicYN="N">Testicular Hydrocele</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
<QualifierName UI="Q000469" MajorTopicYN="N">parasitology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D020577" MajorTopicYN="N">Wolbachia</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
<QualifierName UI="Q000472" MajorTopicYN="N">pathogenicity</QualifierName>
</MeshHeading>
</MeshHeadingList>
<OtherID Source="NLM">PMC187306</OtherID>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2003</Year>
<Month>8</Month>
<Day>23</Day>
<Hour>5</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2003</Year>
<Month>9</Month>
<Day>30</Day>
<Hour>5</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2003</Year>
<Month>8</Month>
<Day>23</Day>
<Hour>5</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">12933853</ArticleId>
<ArticleId IdType="pmc">PMC187306</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004189 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 004189 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= LymphedemaV1 |flux= PubMed |étape= Curation |type= RBID |clé= pubmed:12933853 |texte= Characterization of antibody responses to Wolbachia surface protein in humans with lymphatic filariasis. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:12933853" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \ | NlmPubMed2Wicri -a LymphedemaV1
![]() | This area was generated with Dilib version V0.6.31. | ![]() |