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A case of primary cutaneous nasal type NK/T-cell lymphoma and review of the literature.

Identifieur interne : 003808 ( PubMed/Curation ); précédent : 003807; suivant : 003809

A case of primary cutaneous nasal type NK/T-cell lymphoma and review of the literature.

Auteurs : J. Stokkermans-Dubois [France] ; T. Jouary ; B. Vergier ; M M Delaunay ; A. Taieb

Source :

RBID : pubmed:17135744

Descripteurs français

English descriptors

Abstract

Cutaneous T-cell lymphoma subtypes are now better identified thanks to progress in immunohistochemistry. This article describes a new case of primary cutaneous natural killer/T-cell lymphoma of nasal type (NKTL-NT) and reviews 18 other cases of this rare neoplasm.

DOI: 10.1159/000096201
PubMed: 17135744

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pubmed:17135744

Le document en format XML

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<nlm:affiliation>Skin and Cancer Unit, Department of Dermatology, Saint André Hospital, Bordeaux, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
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<term>Killer Cells, Natural (pathology)</term>
<term>Leg</term>
<term>Lymphedema (diagnosis)</term>
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<term>Lymphoma, T-Cell, Cutaneous (pathology)</term>
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<div type="abstract" xml:lang="en">Cutaneous T-cell lymphoma subtypes are now better identified thanks to progress in immunohistochemistry. This article describes a new case of primary cutaneous natural killer/T-cell lymphoma of nasal type (NKTL-NT) and reviews 18 other cases of this rare neoplasm.</div>
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<AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">Cutaneous T-cell lymphoma subtypes are now better identified thanks to progress in immunohistochemistry. This article describes a new case of primary cutaneous natural killer/T-cell lymphoma of nasal type (NKTL-NT) and reviews 18 other cases of this rare neoplasm.</AbstractText>
<AbstractText Label="CASE REPORT" NlmCategory="METHODS">A 79-year-old man presented with a 3-cm nodular tumor of the left leg occurring on a primary chronic lymphedema of the legs. The lesion was CD56+, CD3 intracytoplasmic+, CD45+ and Epstein-Barr virus+. A comprehensive workup including CT scan and bone marrow biopsy was negative and a diagnosis of NKTL-NT with a primary cutaneous involvement was made. The patient was free of disease under multi-agent chemotherapy after 24 months of follow-up.</AbstractText>
<AbstractText Label="DISCUSSION" NlmCategory="CONCLUSIONS">After reviewing 18 other cases of primary cutaneous NKTL-NT, we conclude that the prognosis of these lymphomas is usually poor. However, limited cutaneous forms have a longer median survival than extracutaneous variants.</AbstractText>
<CopyrightInformation>Copyright (c) 2006 S. Karger AG, Basel.</CopyrightInformation>
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