Dercum's disease (Lipomatosis dolorosa): successful therapy with pregabalin and manual lymphatic drainage and a current overview.
Identifieur interne : 003206 ( PubMed/Curation ); précédent : 003205; suivant : 003207Dercum's disease (Lipomatosis dolorosa): successful therapy with pregabalin and manual lymphatic drainage and a current overview.
Auteurs : Uwe Lange [Allemagne] ; Peter Oelzner ; Christine UhlemannSource :
- Rheumatology international [ 0172-8172 ] ; 2008.
Descripteurs français
- KwdFr :
- Acide gamma-amino-butyrique (analogues et dérivés), Acide gamma-amino-butyrique (usage thérapeutique), Adipose douloureuse (), Adipose douloureuse (anatomopathologie), Adulte d'âge moyen, Analgésiques (usage thérapeutique), Aspiration (technique) (), Femelle, Humains, Hyperalgésie (anatomopathologie), Hyperalgésie (traitement médicamenteux), Hyperalgésie (étiologie), Lymphoedème (), Lymphoedème (anatomopathologie), Lymphoedème (étiologie), Prégabaline, Résultat thérapeutique, Tissu adipeux (anatomopathologie).
- MESH :
- analogues et dérivés : Acide gamma-amino-butyrique.
- anatomopathologie : Adipose douloureuse, Hyperalgésie, Lymphoedème, Tissu adipeux.
- traitement médicamenteux : Hyperalgésie.
- usage thérapeutique : Acide gamma-amino-butyrique, Analgésiques.
- étiologie : Hyperalgésie, Lymphoedème.
- Adipose douloureuse, Adulte d'âge moyen, Aspiration (technique), Femelle, Humains, Lymphoedème, Prégabaline, Résultat thérapeutique.
English descriptors
- KwdEn :
- Adipose Tissue (pathology), Adiposis Dolorosa (complications), Adiposis Dolorosa (pathology), Adiposis Dolorosa (therapy), Analgesics (therapeutic use), Female, Humans, Hyperalgesia (drug therapy), Hyperalgesia (etiology), Hyperalgesia (pathology), Lymphedema (etiology), Lymphedema (pathology), Lymphedema (therapy), Middle Aged, Pregabalin, Suction (methods), Treatment Outcome, gamma-Aminobutyric Acid (analogs & derivatives), gamma-Aminobutyric Acid (therapeutic use).
- MESH :
- chemical , analogs & derivatives : gamma-Aminobutyric Acid.
- chemical , therapeutic use : Analgesics, gamma-Aminobutyric Acid.
- complications : Adiposis Dolorosa.
- drug therapy : Hyperalgesia.
- etiology : Hyperalgesia, Lymphedema.
- methods : Suction.
- pathology : Adipose Tissue, Adiposis Dolorosa, Hyperalgesia, Lymphedema.
- therapy : Adiposis Dolorosa, Lymphedema.
- Female, Humans, Middle Aged, Pregabalin, Treatment Outcome.
Abstract
Dercum's disease which is also termed lipomatosis dolorosa is a rare and relatively unknown disease. In this entity the upper arms, elbows, stomach wall, buttocks, thighs and knees are predominantly affected showing painful subcutaneous adipose tissue deposits. In addition severe hyperalgesia can be triggered by light pressure and touch. Analgesic and/or nonsteroidal antirheumatic drugs have usually only a minor or no effect. Here, we report a patient with Dercum's disease who was successfully treated with pregabalin and manual lymphatic drainage, and present a current overview of the literature.
DOI: 10.1007/s00296-008-0635-3
PubMed: 18604537
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pubmed:18604537Le document en format XML
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<author><name sortKey="Oelzner, Peter" sort="Oelzner, Peter" uniqKey="Oelzner P" first="Peter" last="Oelzner">Peter Oelzner</name>
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<term>Adiposis Dolorosa (pathology)</term>
<term>Adiposis Dolorosa (therapy)</term>
<term>Analgesics (therapeutic use)</term>
<term>Female</term>
<term>Humans</term>
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<term>Acide gamma-amino-butyrique (usage thérapeutique)</term>
<term>Adipose douloureuse ()</term>
<term>Adipose douloureuse (anatomopathologie)</term>
<term>Adulte d'âge moyen</term>
<term>Analgésiques (usage thérapeutique)</term>
<term>Aspiration (technique) ()</term>
<term>Femelle</term>
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<term>Hyperalgésie (étiologie)</term>
<term>Lymphoedème ()</term>
<term>Lymphoedème (anatomopathologie)</term>
<term>Lymphoedème (étiologie)</term>
<term>Prégabaline</term>
<term>Résultat thérapeutique</term>
<term>Tissu adipeux (anatomopathologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>gamma-Aminobutyric Acid</term>
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<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Analgesics</term>
<term>gamma-Aminobutyric Acid</term>
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<keywords scheme="MESH" qualifier="analogues et dérivés" xml:lang="fr"><term>Acide gamma-amino-butyrique</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Adipose douloureuse</term>
<term>Hyperalgésie</term>
<term>Lymphoedème</term>
<term>Tissu adipeux</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Adiposis Dolorosa</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Hyperalgesia</term>
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<term>Lymphedema</term>
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<term>Adiposis Dolorosa</term>
<term>Hyperalgesia</term>
<term>Lymphedema</term>
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<term>Lymphedema</term>
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<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Hyperalgésie</term>
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<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Acide gamma-amino-butyrique</term>
<term>Analgésiques</term>
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<term>Lymphoedème</term>
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<keywords scheme="MESH" xml:lang="en"><term>Female</term>
<term>Humans</term>
<term>Middle Aged</term>
<term>Pregabalin</term>
<term>Treatment Outcome</term>
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<term>Adulte d'âge moyen</term>
<term>Aspiration (technique)</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lymphoedème</term>
<term>Prégabaline</term>
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<front><div type="abstract" xml:lang="en">Dercum's disease which is also termed lipomatosis dolorosa is a rare and relatively unknown disease. In this entity the upper arms, elbows, stomach wall, buttocks, thighs and knees are predominantly affected showing painful subcutaneous adipose tissue deposits. In addition severe hyperalgesia can be triggered by light pressure and touch. Analgesic and/or nonsteroidal antirheumatic drugs have usually only a minor or no effect. Here, we report a patient with Dercum's disease who was successfully treated with pregabalin and manual lymphatic drainage, and present a current overview of the literature.</div>
</front>
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<ArticleTitle>Dercum's disease (Lipomatosis dolorosa): successful therapy with pregabalin and manual lymphatic drainage and a current overview.</ArticleTitle>
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<Abstract><AbstractText>Dercum's disease which is also termed lipomatosis dolorosa is a rare and relatively unknown disease. In this entity the upper arms, elbows, stomach wall, buttocks, thighs and knees are predominantly affected showing painful subcutaneous adipose tissue deposits. In addition severe hyperalgesia can be triggered by light pressure and touch. Analgesic and/or nonsteroidal antirheumatic drugs have usually only a minor or no effect. Here, we report a patient with Dercum's disease who was successfully treated with pregabalin and manual lymphatic drainage, and present a current overview of the literature.</AbstractText>
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