Dercum's disease (Lipomatosis dolorosa): successful therapy with pregabalin and manual lymphatic drainage and a current overview.
Identifieur interne : 003206 ( PubMed/Curation ); précédent : 003205; suivant : 003207Dercum's disease (Lipomatosis dolorosa): successful therapy with pregabalin and manual lymphatic drainage and a current overview.
Auteurs : Uwe Lange [Allemagne] ; Peter Oelzner ; Christine UhlemannSource :
- Rheumatology international [ 0172-8172 ] ; 2008.
Descripteurs français
- KwdFr :
- Acide gamma-amino-butyrique (analogues et dérivés), Acide gamma-amino-butyrique (usage thérapeutique), Adipose douloureuse (), Adipose douloureuse (anatomopathologie), Adulte d'âge moyen, Analgésiques (usage thérapeutique), Aspiration (technique) (), Femelle, Humains, Hyperalgésie (anatomopathologie), Hyperalgésie (traitement médicamenteux), Hyperalgésie (étiologie), Lymphoedème (), Lymphoedème (anatomopathologie), Lymphoedème (étiologie), Prégabaline, Résultat thérapeutique, Tissu adipeux (anatomopathologie).
- MESH :
- analogues et dérivés : Acide gamma-amino-butyrique.
- anatomopathologie : Adipose douloureuse, Hyperalgésie, Lymphoedème, Tissu adipeux.
- traitement médicamenteux : Hyperalgésie.
- usage thérapeutique : Acide gamma-amino-butyrique, Analgésiques.
- étiologie : Hyperalgésie, Lymphoedème.
- Adipose douloureuse, Adulte d'âge moyen, Aspiration (technique), Femelle, Humains, Lymphoedème, Prégabaline, Résultat thérapeutique.
English descriptors
- KwdEn :
- Adipose Tissue (pathology), Adiposis Dolorosa (complications), Adiposis Dolorosa (pathology), Adiposis Dolorosa (therapy), Analgesics (therapeutic use), Female, Humans, Hyperalgesia (drug therapy), Hyperalgesia (etiology), Hyperalgesia (pathology), Lymphedema (etiology), Lymphedema (pathology), Lymphedema (therapy), Middle Aged, Pregabalin, Suction (methods), Treatment Outcome, gamma-Aminobutyric Acid (analogs & derivatives), gamma-Aminobutyric Acid (therapeutic use).
- MESH :
- chemical , analogs & derivatives : gamma-Aminobutyric Acid.
- chemical , therapeutic use : Analgesics, gamma-Aminobutyric Acid.
- complications : Adiposis Dolorosa.
- drug therapy : Hyperalgesia.
- etiology : Hyperalgesia, Lymphedema.
- methods : Suction.
- pathology : Adipose Tissue, Adiposis Dolorosa, Hyperalgesia, Lymphedema.
- therapy : Adiposis Dolorosa, Lymphedema.
- Female, Humans, Middle Aged, Pregabalin, Treatment Outcome.
Abstract
Dercum's disease which is also termed lipomatosis dolorosa is a rare and relatively unknown disease. In this entity the upper arms, elbows, stomach wall, buttocks, thighs and knees are predominantly affected showing painful subcutaneous adipose tissue deposits. In addition severe hyperalgesia can be triggered by light pressure and touch. Analgesic and/or nonsteroidal antirheumatic drugs have usually only a minor or no effect. Here, we report a patient with Dercum's disease who was successfully treated with pregabalin and manual lymphatic drainage, and present a current overview of the literature.
DOI: 10.1007/s00296-008-0635-3
PubMed: 18604537
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xml:lang="en"><term>Hyperalgesia</term><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Suction</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Adipose Tissue</term><term>Adiposis Dolorosa</term><term>Hyperalgesia</term><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Adiposis Dolorosa</term><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Hyperalgésie</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Acide gamma-amino-butyrique</term><term>Analgésiques</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Hyperalgésie</term><term>Lymphoedème</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Female</term><term>Humans</term><term>Middle Aged</term><term>Pregabalin</term><term>Treatment 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In this entity the upper arms, elbows, stomach wall, buttocks, thighs and knees are predominantly affected showing painful subcutaneous adipose tissue deposits. In addition severe hyperalgesia can be triggered by light pressure and touch. Analgesic and/or nonsteroidal antirheumatic drugs have usually only a minor or no effect. Here, we report a patient with Dercum's disease who was successfully treated with pregabalin and manual lymphatic drainage, and present a current overview of the literature.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">18604537</PMID><DateCreated><Year>2008</Year><Month>09</Month><Day>30</Day></DateCreated><DateCompleted><Year>2009</Year><Month>04</Month><Day>24</Day></DateCompleted><DateRevised><Year>2015</Year><Month>11</Month><Day>19</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">0172-8172</ISSN><JournalIssue CitedMedium="Print"><Volume>29</Volume><Issue>1</Issue><PubDate><Year>2008</Year><Month>Nov</Month></PubDate></JournalIssue><Title>Rheumatology international</Title><ISOAbbreviation>Rheumatol. Int.</ISOAbbreviation></Journal><ArticleTitle>Dercum's disease (Lipomatosis dolorosa): successful therapy with pregabalin and manual lymphatic drainage and a current overview.</ArticleTitle><Pagination><MedlinePgn>17-22</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s00296-008-0635-3</ELocationID><Abstract><AbstractText>Dercum's disease which is also termed lipomatosis dolorosa is a rare and relatively unknown disease. In this entity the upper arms, elbows, stomach wall, buttocks, thighs and knees are predominantly affected showing painful subcutaneous adipose tissue deposits. In addition severe hyperalgesia can be triggered by light pressure and touch. Analgesic and/or nonsteroidal antirheumatic drugs have usually only a minor or no effect. Here, we report a patient with Dercum's disease who was successfully treated with pregabalin and manual lymphatic drainage, and present a current overview of the literature.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Lange</LastName><ForeName>Uwe</ForeName><Initials>U</Initials><AffiliationInfo><Affiliation>Kerckhoff-Clinic, Bad Nauheim, Germany, U.Lange@kerckhoff-klinik.de</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Oelzner</LastName><ForeName>Peter</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Uhlemann</LastName><ForeName>Christine</ForeName><Initials>C</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2008</Year><Month>07</Month><Day>05</Day></ArticleDate></Article><MedlineJournalInfo><Country>Germany</Country><MedlineTA>Rheumatol Int</MedlineTA><NlmUniqueID>8206885</NlmUniqueID><ISSNLinking>0172-8172</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000700">Analgesics</NameOfSubstance></Chemical><Chemical><RegistryNumber>55JG375S6M</RegistryNumber><NameOfSubstance UI="D000069583">Pregabalin</NameOfSubstance></Chemical><Chemical><RegistryNumber>56-12-2</RegistryNumber><NameOfSubstance UI="D005680">gamma-Aminobutyric Acid</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000273" MajorTopicYN="N">Adipose Tissue</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000274" MajorTopicYN="N">Adiposis Dolorosa</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000700" MajorTopicYN="N">Analgesics</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006930" MajorTopicYN="N">Hyperalgesia</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000069583" MajorTopicYN="N">Pregabalin</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013396" MajorTopicYN="N">Suction</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016896" MajorTopicYN="N">Treatment Outcome</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005680" MajorTopicYN="N">gamma-Aminobutyric Acid</DescriptorName><QualifierName UI="Q000031" MajorTopicYN="Y">analogs & derivatives</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2008</Year><Month>01</Month><Day>09</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2008</Year><Month>06</Month><Day>15</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2008</Year><Month>7</Month><Day>8</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2009</Year><Month>4</Month><Day>25</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2008</Year><Month>7</Month><Day>8</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">18604537</ArticleId><ArticleId IdType="doi">10.1007/s00296-008-0635-3</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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