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Arm symptoms and overall survival in Brazilian patients with advanced breast cancer.

Identifieur interne : 002795 ( PubMed/Curation ); précédent : 002794; suivant : 002796

Arm symptoms and overall survival in Brazilian patients with advanced breast cancer.

Auteurs : Anke Bergmann [Brésil] ; Nathalia Santos Bourrus ; Cristiane Monteiro De Carvalho ; Ricardo De Almeida Dias ; Erica Alves Nogueira Fabro ; Núria Silva Sales ; Suzana Sales De Aguiar

Source :

RBID : pubmed:22393967

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English descriptors

Abstract

Advanced breast cancer is a very frequent serious public health problem.

PubMed: 22393967

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pubmed:22393967

Le document en format XML

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<title xml:lang="en">Arm symptoms and overall survival in Brazilian patients with advanced breast cancer.</title>
<author>
<name sortKey="Bergmann, Anke" sort="Bergmann, Anke" uniqKey="Bergmann A" first="Anke" last="Bergmann">Anke Bergmann</name>
<affiliation wicri:level="1">
<nlm:affiliation>Centro Universitário Augusto Motta and Instituto Nacional de Cancer, Brazil. bergmann@inca.gov.br</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Centro Universitário Augusto Motta and Instituto Nacional de Cancer</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Bourrus, Nathalia Santos" sort="Bourrus, Nathalia Santos" uniqKey="Bourrus N" first="Nathalia Santos" last="Bourrus">Nathalia Santos Bourrus</name>
</author>
<author>
<name sortKey="De Carvalho, Cristiane Monteiro" sort="De Carvalho, Cristiane Monteiro" uniqKey="De Carvalho C" first="Cristiane Monteiro" last="De Carvalho">Cristiane Monteiro De Carvalho</name>
</author>
<author>
<name sortKey="Dias, Ricardo De Almeida" sort="Dias, Ricardo De Almeida" uniqKey="Dias R" first="Ricardo De Almeida" last="Dias">Ricardo De Almeida Dias</name>
</author>
<author>
<name sortKey="Fabro, Erica Alves Nogueira" sort="Fabro, Erica Alves Nogueira" uniqKey="Fabro E" first="Erica Alves Nogueira" last="Fabro">Erica Alves Nogueira Fabro</name>
</author>
<author>
<name sortKey="Sales, Nuria Silva" sort="Sales, Nuria Silva" uniqKey="Sales N" first="Núria Silva" last="Sales">Núria Silva Sales</name>
</author>
<author>
<name sortKey="De Aguiar, Suzana Sales" sort="De Aguiar, Suzana Sales" uniqKey="De Aguiar S" first="Suzana Sales" last="De Aguiar">Suzana Sales De Aguiar</name>
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<title xml:lang="en">Arm symptoms and overall survival in Brazilian patients with advanced breast cancer.</title>
<author>
<name sortKey="Bergmann, Anke" sort="Bergmann, Anke" uniqKey="Bergmann A" first="Anke" last="Bergmann">Anke Bergmann</name>
<affiliation wicri:level="1">
<nlm:affiliation>Centro Universitário Augusto Motta and Instituto Nacional de Cancer, Brazil. bergmann@inca.gov.br</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Centro Universitário Augusto Motta and Instituto Nacional de Cancer</wicri:regionArea>
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<author>
<name sortKey="Bourrus, Nathalia Santos" sort="Bourrus, Nathalia Santos" uniqKey="Bourrus N" first="Nathalia Santos" last="Bourrus">Nathalia Santos Bourrus</name>
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<author>
<name sortKey="De Carvalho, Cristiane Monteiro" sort="De Carvalho, Cristiane Monteiro" uniqKey="De Carvalho C" first="Cristiane Monteiro" last="De Carvalho">Cristiane Monteiro De Carvalho</name>
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<author>
<name sortKey="Dias, Ricardo De Almeida" sort="Dias, Ricardo De Almeida" uniqKey="Dias R" first="Ricardo De Almeida" last="Dias">Ricardo De Almeida Dias</name>
</author>
<author>
<name sortKey="Fabro, Erica Alves Nogueira" sort="Fabro, Erica Alves Nogueira" uniqKey="Fabro E" first="Erica Alves Nogueira" last="Fabro">Erica Alves Nogueira Fabro</name>
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<name sortKey="Sales, Nuria Silva" sort="Sales, Nuria Silva" uniqKey="Sales N" first="Núria Silva" last="Sales">Núria Silva Sales</name>
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<name sortKey="De Aguiar, Suzana Sales" sort="De Aguiar, Suzana Sales" uniqKey="De Aguiar S" first="Suzana Sales" last="De Aguiar">Suzana Sales De Aguiar</name>
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<series>
<title level="j">Asian Pacific journal of cancer prevention : APJCP</title>
<idno type="eISSN">2476-762X</idno>
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<date when="2011" type="published">2011</date>
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<keywords scheme="KwdEn" xml:lang="en">
<term>Adult</term>
<term>Aged</term>
<term>Arm (physiopathology)</term>
<term>Brazil</term>
<term>Breast Neoplasms (diagnosis)</term>
<term>Breast Neoplasms (mortality)</term>
<term>Cohort Studies</term>
<term>Disease-Free Survival</term>
<term>Female</term>
<term>Humans</term>
<term>Kaplan-Meier Estimate</term>
<term>Lymphedema</term>
<term>Middle Aged</term>
<term>Obesity</term>
<term>Pain</term>
<term>Paresthesia</term>
<term>Proportional Hazards Models</term>
<term>Retrospective Studies</term>
<term>Shoulder</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Bras (physiopathologie)</term>
<term>Brésil</term>
<term>Douleur</term>
<term>Estimation de Kaplan-Meier</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lymphoedème</term>
<term>Modèles de hasards proportionnels</term>
<term>Obésité</term>
<term>Paresthésie</term>
<term>Sujet âgé</term>
<term>Survie sans rechute</term>
<term>Tumeurs du sein (diagnostic)</term>
<term>Tumeurs du sein (mortalité)</term>
<term>Épaule</term>
<term>Études de cohortes</term>
<term>Études rétrospectives</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en">
<term>Brazil</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en">
<term>Breast Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr">
<term>Tumeurs du sein</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en">
<term>Breast Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="mortalité" xml:lang="fr">
<term>Tumeurs du sein</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr">
<term>Bras</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en">
<term>Arm</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Adult</term>
<term>Aged</term>
<term>Cohort Studies</term>
<term>Disease-Free Survival</term>
<term>Female</term>
<term>Humans</term>
<term>Kaplan-Meier Estimate</term>
<term>Lymphedema</term>
<term>Middle Aged</term>
<term>Obesity</term>
<term>Pain</term>
<term>Paresthesia</term>
<term>Proportional Hazards Models</term>
<term>Retrospective Studies</term>
<term>Shoulder</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Brésil</term>
<term>Douleur</term>
<term>Estimation de Kaplan-Meier</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lymphoedème</term>
<term>Modèles de hasards proportionnels</term>
<term>Obésité</term>
<term>Paresthésie</term>
<term>Sujet âgé</term>
<term>Survie sans rechute</term>
<term>Épaule</term>
<term>Études de cohortes</term>
<term>Études rétrospectives</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr">
<term>Brésil</term>
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<front>
<div type="abstract" xml:lang="en">Advanced breast cancer is a very frequent serious public health problem.</div>
</front>
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<pubmed>
<MedlineCitation Status="MEDLINE" Owner="NLM">
<PMID Version="1">22393967</PMID>
<DateCreated>
<Year>2012</Year>
<Month>03</Month>
<Day>07</Day>
</DateCreated>
<DateCompleted>
<Year>2012</Year>
<Month>07</Month>
<Day>13</Day>
</DateCompleted>
<DateRevised>
<Year>2017</Year>
<Month>03</Month>
<Day>08</Day>
</DateRevised>
<Article PubModel="Print">
<Journal>
<ISSN IssnType="Electronic">2476-762X</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>12</Volume>
<Issue>11</Issue>
<PubDate>
<Year>2011</Year>
</PubDate>
</JournalIssue>
<Title>Asian Pacific journal of cancer prevention : APJCP</Title>
<ISOAbbreviation>Asian Pac. J. Cancer Prev.</ISOAbbreviation>
</Journal>
<ArticleTitle>Arm symptoms and overall survival in Brazilian patients with advanced breast cancer.</ArticleTitle>
<Pagination>
<MedlinePgn>2939-42</MedlinePgn>
</Pagination>
<Abstract>
<AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">Advanced breast cancer is a very frequent serious public health problem.</AbstractText>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">This study aimed to analyze the prevalence of arm symptoms and overall survival in affected patients.</AbstractText>
<AbstractText Label="METHODOLOGY" NlmCategory="METHODS">A retrospective cohort study was accomplished in 196 women presenting with advanced breast cancer. A descriptive analysis was carried out by and overall survival probabilities were calculated according to Kaplan-Meier method and Cox regression.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">These included 196 woman had a medium age of 55.9 years, the majority being obese (71.3%) and having a IIIB clinical staging (52.3%). The most prevalent arm symptoms were pain (54.6%), paresthesia in upper limb (8.5%), lymphedema (> 200 ml) (6.6%), shoulder restriction (4.7%) and axillary web syndrome (0.6%). The median follow-up was 18.7 months (SD 7,33), 4.0% of the patients had metastasis and 31.6% were dead. The mean free disease survival was 20.4 months (95% CI 18.4-22.4), and the mean survival time was 26.3 months (95% CI 24.7-28.0). After adjusted the association with arm symptom and overall survival for clinical stage and presence of distant metastasis, the shoulder restriction was a predict variable, were represents the risk 2.59 for worse survival in compared with woman with no shoulder restriction (CI 95% 1.06-5.98).</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The population studied at this study presented high prevalence of complications earlier than neo adjuvant treatment. After controlling for effects of tumor variables, the shoulder restriction was statistically associated with poor overall survival after 2 years.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y">
<Author ValidYN="Y">
<LastName>Bergmann</LastName>
<ForeName>Anke</ForeName>
<Initials>A</Initials>
<AffiliationInfo>
<Affiliation>Centro Universitário Augusto Motta and Instituto Nacional de Cancer, Brazil. bergmann@inca.gov.br</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Bourrus</LastName>
<ForeName>Nathalia Santos</ForeName>
<Initials>NS</Initials>
</Author>
<Author ValidYN="Y">
<LastName>de Carvalho</LastName>
<ForeName>Cristiane Monteiro</ForeName>
<Initials>CM</Initials>
</Author>
<Author ValidYN="Y">
<LastName>Dias</LastName>
<ForeName>Ricardo de Almeida</ForeName>
<Initials>Rde A</Initials>
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<Author ValidYN="Y">
<LastName>Fabro</LastName>
<ForeName>Erica Alves Nogueira</ForeName>
<Initials>EA</Initials>
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<Author ValidYN="Y">
<LastName>Sales</LastName>
<ForeName>Núria Silva</ForeName>
<Initials>NS</Initials>
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<Author ValidYN="Y">
<LastName>de Aguiar</LastName>
<ForeName>Suzana Sales</ForeName>
<Initials>SS</Initials>
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<Language>eng</Language>
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<MedlineJournalInfo>
<Country>Thailand</Country>
<MedlineTA>Asian Pac J Cancer Prev</MedlineTA>
<NlmUniqueID>101130625</NlmUniqueID>
<ISSNLinking>1513-7368</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList>
<MeshHeading>
<DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
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<MeshHeading>
<DescriptorName UI="D001132" MajorTopicYN="N">Arm</DescriptorName>
<QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D001938" MajorTopicYN="N" Type="Geographic">Brazil</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D001943" MajorTopicYN="N">Breast Neoplasms</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName>
<QualifierName UI="Q000401" MajorTopicYN="Y">mortality</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D015331" MajorTopicYN="N">Cohort Studies</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D018572" MajorTopicYN="N">Disease-Free Survival</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D053208" MajorTopicYN="N">Kaplan-Meier Estimate</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D009765" MajorTopicYN="N">Obesity</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D010146" MajorTopicYN="N">Pain</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D010292" MajorTopicYN="N">Paresthesia</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D016016" MajorTopicYN="N">Proportional Hazards Models</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D012782" MajorTopicYN="N">Shoulder</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
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<Year>2012</Year>
<Month>3</Month>
<Day>8</Day>
<Hour>6</Hour>
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