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[Chronic eyelid oedema and rosacea (Morbus Morbihan): diagnostic and therapeutic challenges].

Identifieur interne : 002768 ( PubMed/Curation ); précédent : 002767; suivant : 002769

[Chronic eyelid oedema and rosacea (Morbus Morbihan): diagnostic and therapeutic challenges].

Auteurs : G. Renieri [Italie] ; C. Brochhausen ; N. Pfeiffer ; S. Pitz

Source :

RBID : pubmed:21249610

Descripteurs français

English descriptors

Abstract

Morbus Morbihan is a rare complication of rosacea, consisting of a persistent lymphoedema of the upper part of the face. It has typically a chronic course, unspecific histopathological findings and an extreme refractoriness to therapy.

DOI: 10.1055/s-0029-1245960
PubMed: 21249610

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pubmed:21249610

Le document en format XML

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<title xml:lang="en">[Chronic eyelid oedema and rosacea (Morbus Morbihan): diagnostic and therapeutic challenges].</title>
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<name sortKey="Renieri, G" sort="Renieri, G" uniqKey="Renieri G" first="G" last="Renieri">G. Renieri</name>
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<nlm:affiliation>Augenklinik und Poliklinik, Universitätsmedizin der Johannes-Gutenberg-Universität Mainz, Langenbeckstrasse 1, Mainz. giulia_renieri@iol.it</nlm:affiliation>
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<name sortKey="Brochhausen, C" sort="Brochhausen, C" uniqKey="Brochhausen C" first="C" last="Brochhausen">C. Brochhausen</name>
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<name sortKey="Pfeiffer, N" sort="Pfeiffer, N" uniqKey="Pfeiffer N" first="N" last="Pfeiffer">N. Pfeiffer</name>
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<name sortKey="Pitz, S" sort="Pitz, S" uniqKey="Pitz S" first="S" last="Pitz">S. Pitz</name>
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<term>Adult</term>
<term>Anti-Inflammatory Agents (therapeutic use)</term>
<term>Chronic Disease</term>
<term>Edema (diagnosis)</term>
<term>Edema (therapy)</term>
<term>Eyelid Diseases (diagnosis)</term>
<term>Eyelid Diseases (therapy)</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Ophthalmologic Surgical Procedures (methods)</term>
<term>Rosacea (diagnosis)</term>
<term>Rosacea (therapy)</term>
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<term>Treatment Outcome</term>
<term>Triamcinolone (therapeutic use)</term>
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<term>Adulte</term>
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<term>Anti-inflammatoires (usage thérapeutique)</term>
<term>Femelle</term>
<term>Humains</term>
<term>Maladie chronique</term>
<term>Maladies de la paupière ()</term>
<term>Maladies de la paupière (diagnostic)</term>
<term>Mâle</term>
<term>Oedème ()</term>
<term>Oedème (diagnostic)</term>
<term>Procédures de chirurgie ophtalmologique ()</term>
<term>Rosacée ()</term>
<term>Rosacée (diagnostic)</term>
<term>Résultat thérapeutique</term>
<term>Syndrome</term>
<term>Triamcinolone (usage thérapeutique)</term>
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<term>Anti-Inflammatory Agents</term>
<term>Triamcinolone</term>
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<term>Edema</term>
<term>Eyelid Diseases</term>
<term>Rosacea</term>
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<term>Maladies de la paupière</term>
<term>Oedème</term>
<term>Rosacée</term>
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<term>Ophthalmologic Surgical Procedures</term>
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<term>Eyelid Diseases</term>
<term>Rosacea</term>
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<term>Humans</term>
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<div type="abstract" xml:lang="en">Morbus Morbihan is a rare complication of rosacea, consisting of a persistent lymphoedema of the upper part of the face. It has typically a chronic course, unspecific histopathological findings and an extreme refractoriness to therapy.</div>
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<Month>05</Month>
<Day>17</Day>
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<Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
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<Title>Klinische Monatsblatter fur Augenheilkunde</Title>
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<ArticleTitle>[Chronic eyelid oedema and rosacea (Morbus Morbihan): diagnostic and therapeutic challenges].</ArticleTitle>
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<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Morbus Morbihan is a rare complication of rosacea, consisting of a persistent lymphoedema of the upper part of the face. It has typically a chronic course, unspecific histopathological findings and an extreme refractoriness to therapy.</AbstractText>
<AbstractText Label="PATIENTS AND METHODS" NlmCategory="METHODS">Between February 2008 and January 2010, 5 patients with Morbus Morbihan were observed at the Department of Ophthalmology of the University Medical Centre Mainz. In the present cohort study, we describe the clinical, laboratory and histological findings that led to the diagnosis. The course of the affection and the results of different therapeutic options are also reported.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Each patient underwent a complete ophthalmological examination, as well as general and dermatological consultations. All patients showed facial skin alterations typical for rosacea. 4 out of 5 subjects underwent a lid biopsy to confirm the diagnosis of Morbus Morbihan, one patient refused it. Initial treatment consisted of various systemic and local medical therapies, however, with poor success. One patient had intravenous therapy with corticosteroids elsewhere with no effect. We treated 3 cases with intralesional triamcinolone injections with good results. 2 patients underwent upper lid blepharoplasty. Results of surgery remained stable also due to manual lymph drainage and intralesional injections of triamcinolon. No complications or side effects were seen in patients treated with triamcinolone.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Morbus Morbihan can be diagnosed only after excluding other conditions leading to chronic lid swelling. In our series, good results were achieved with intralesional injection of triamcinolone. Surgery also led to relevant improvements for a long period (13 months), with some adjuvant therapy. The treatment of chronic eyelid oedema associated with rosacea remains a challenge for the ophthalmologist and the oculoplastic surgeon.</AbstractText>
<CopyrightInformation>© Georg Thieme Verlag KG Stuttgart · New York.</CopyrightInformation>
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<VernacularTitle>Chronisches Lidödem assoziiert mit Rosazea (Morbus Morbihan): Differenzialdiagnostische Schwierigkeiten und Therapieoptionen.</VernacularTitle>
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