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A randomized trial of exercise on well-being and function following breast cancer surgery: the RESTORE trial.

Identifieur interne : 002352 ( PubMed/Curation ); précédent : 002351; suivant : 002353

A randomized trial of exercise on well-being and function following breast cancer surgery: the RESTORE trial.

Auteurs : Roger T. Anderson [États-Unis] ; Gretchen G. Kimmick ; Thomas P. Mccoy ; Judith Hopkins ; Edward Levine ; Gary Miller ; Paul Ribisl ; Shannon L. Mihalko

Source :

RBID : pubmed:22160629

Descripteurs français

English descriptors

Abstract

This study aimed to determine the effect of a moderate, tailored exercise program on health-related quality of life, physical function, and arm volume in women receiving treatment for nonmetastatic breast cancer.

DOI: 10.1007/s11764-011-0208-4
PubMed: 22160629

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pubmed:22160629

Le document en format XML

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<term>Aged, 80 and over</term>
<term>Breast Neoplasms (rehabilitation)</term>
<term>Breast Neoplasms (surgery)</term>
<term>Cohort Studies</term>
<term>Exercise</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Lymphedema (prevention & control)</term>
<term>Mastectomy</term>
<term>Middle Aged</term>
<term>Neoplasm Staging</term>
<term>Patient Compliance</term>
<term>Patient Education as Topic</term>
<term>Physical Therapy Modalities</term>
<term>Postoperative Complications</term>
<term>Prognosis</term>
<term>Quality of Life</term>
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<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Complications postopératoires</term>
<term>Exercice physique</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lymphoedème ()</term>
<term>Mastectomie</term>
<term>Méthode en simple aveugle</term>
<term>Observance thérapeutique</term>
<term>Pronostic</term>
<term>Qualité de vie</term>
<term>Stade de la tumeur</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Techniques de physiothérapie</term>
<term>Tumeurs du sein ()</term>
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<term>Lymphedema</term>
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<term>Breast Neoplasms</term>
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<term>Tumeurs du sein</term>
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<term>Adult</term>
<term>Aged</term>
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<term>Follow-Up Studies</term>
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<term>Mastectomy</term>
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<term>Neoplasm Staging</term>
<term>Patient Compliance</term>
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<term>Adulte d'âge moyen</term>
<term>Complications postopératoires</term>
<term>Exercice physique</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lymphoedème</term>
<term>Mastectomie</term>
<term>Méthode en simple aveugle</term>
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<term>Pronostic</term>
<term>Qualité de vie</term>
<term>Stade de la tumeur</term>
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<term>Sujet âgé de 80 ans ou plus</term>
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<div type="abstract" xml:lang="en">This study aimed to determine the effect of a moderate, tailored exercise program on health-related quality of life, physical function, and arm volume in women receiving treatment for nonmetastatic breast cancer.</div>
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<Day>20</Day>
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<ISSN IssnType="Electronic">1932-2267</ISSN>
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<Title>Journal of cancer survivorship : research and practice</Title>
<ISOAbbreviation>J Cancer Surviv</ISOAbbreviation>
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<ArticleTitle>A randomized trial of exercise on well-being and function following breast cancer surgery: the RESTORE trial.</ArticleTitle>
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<AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">This study aimed to determine the effect of a moderate, tailored exercise program on health-related quality of life, physical function, and arm volume in women receiving treatment for nonmetastatic breast cancer.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Women who were within 4-12 weeks of surgery for stage I-III breast cancer were randomized to center-based exercise and lymphedema education intervention or patient education. Functional assessment of cancer therapy-breast cancer (FACT-B), 6-min walk, and arm volume were performed at 3-month intervals through 18 months. Repeated measures analysis of covariance was used to model the total meters walked over time, FACT-B scores, and arm volume. Models were adjusted for baseline measurement, baseline affected arm volume, number of nodes removed, age, self-reported symptoms, baseline SF-12 mental and physical component scores, visit, and treatment group.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Of the recruited 104 women, 82 completed all 18 months. Mean age (range) was 53.6 (32-82) years; 88% were Caucasian; 45% were employed full time; 44% were overweight; and 28% obese. Approximately, 46% had breast-conserving surgery; 79% had axillary node dissection; 59% received chemotherapy; and 64% received radiation. The intervention resulted in an average increase of 34.3 ml (SD = 12.8) versus patient education (p = 0.01). Changes in FACT-B scores and arm volumes were not significantly different.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">With this early exercise intervention after breast cancer diagnosis, a significant improvement was achieved in physical function, with no decline in health-related quality of life or detrimental effect on arm volume.</AbstractText>
<AbstractText Label="IMPLICATIONS FOR CANCER SURVIVORS" NlmCategory="CONCLUSIONS">Starting a supervised exercise regimen that is tailored to an individual's strength and stamina within 3 months following breast cancer surgery appears safe and may hasten improvements in physical functioning.</AbstractText>
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<LastName>Anderson</LastName>
<ForeName>Roger T</ForeName>
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<Affiliation>Department of Public Health Sciences, College of Medicine, Penn State Milton S. Hershey Medical Center, 600 Centerview Drive, Suite 2200, P.O. Box 855, Hershey, PA 17033-0855, USA. rtanders@psu.edu</Affiliation>
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