Duration of detection of anti-BmR1 IgG4 antibodies after mass-drug administration (MDA) in Sarawak, Malaysia.
Identifieur interne : 002146 ( PubMed/Curation ); précédent : 002145; suivant : 002147Duration of detection of anti-BmR1 IgG4 antibodies after mass-drug administration (MDA) in Sarawak, Malaysia.
Auteurs : R. Noordin [Malaisie] ; J. Muhi ; Z. Md Idris ; N. Arifin ; A. KiyuSource :
- Tropical biomedicine [ 0127-5720 ] ; 2012.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Animaux, Anticorps antihelminthe (sang), Antigènes d'helminthe, Brugia (immunologie), Enfant, Enfant d'âge préscolaire, Facteurs temps, Filaricides (administration et posologie), Filariose lymphatique (immunologie), Filariose lymphatique (traitement médicamenteux), Filariose lymphatique (épidémiologie), Humains, Immunoglobuline G (sang), Jeune adulte, Malaisie (épidémiologie), Mâle, Protéines recombinantes, Sujet âgé, Sujet âgé de 80 ans ou plus, Traitement médicamenteux (), Études séroépidémiologiques.
- MESH :
- administration et posologie : Filaricides.
- immunologie : Brugia, Filariose lymphatique.
- sang : Anticorps antihelminthe, Immunoglobuline G.
- traitement médicamenteux : Filariose lymphatique.
- épidémiologie : Filariose lymphatique, Malaisie.
- Adolescent, Adulte, Adulte d'âge moyen, Animaux, Antigènes d'helminthe, Enfant, Enfant d'âge préscolaire, Facteurs temps, Humains, Jeune adulte, Mâle, Protéines recombinantes, Sujet âgé, Sujet âgé de 80 ans ou plus, Traitement médicamenteux, Études séroépidémiologiques.
- Wicri :
- geographic : Malaisie.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Aged, 80 and over, Animals, Antibodies, Helminth (blood), Antigens, Helminth, Brugia (immunology), Child, Child, Preschool, Drug Therapy (methods), Elephantiasis, Filarial (drug therapy), Elephantiasis, Filarial (epidemiology), Elephantiasis, Filarial (immunology), Filaricides (administration & dosage), Humans, Immunoglobulin G (blood), Malaysia (epidemiology), Male, Middle Aged, Recombinant Proteins, Seroepidemiologic Studies, Time Factors, Young Adult.
- MESH :
- chemical , administration & dosage : Filaricides.
- chemical , blood : Antibodies, Helminth, Immunoglobulin G.
- geographic , epidemiology : Malaysia.
- drug therapy : Elephantiasis, Filarial.
- epidemiology : Elephantiasis, Filarial.
- immunology : Brugia, Elephantiasis, Filarial.
- methods : Drug Therapy.
- Adolescent, Adult, Aged, Aged, 80 and over, Animals, Antigens, Helminth, Child, Child, Preschool, Humans, Male, Middle Aged, Recombinant Proteins, Seroepidemiologic Studies, Time Factors, Young Adult.
Abstract
The detection rates of brugian filariasis in three regions of Sarawak namely Central, North and South after three courses of mass drug administration (MDA) from year 2004 to 2006 was investigated. A recombinant BmR1 antigen-based IgG4 detection test, named Brugia Rapid and night blood smear for microfilaria (mf) detection were used. All three regions recorded a sharp fall in mf positive rates after a year post-MDA. Meanwhile Brugia Rapid positive rates declined more gradually to 3.8% and 5.6% of the pre-MDA levels in the Central and North regions, respectively. This study showed that in filariasis endemic areas in Sarawak, anti-filarial IgG4 antibodies to BmR1, as detected by the Brugia Rapid test, were positive for one to two years after mf disappearance.
PubMed: 22543621
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A recombinant BmR1 antigen-based IgG4 detection test, named Brugia Rapid and night blood smear for microfilaria (mf) detection were used. All three regions recorded a sharp fall in mf positive rates after a year post-MDA. Meanwhile Brugia Rapid positive rates declined more gradually to 3.8% and 5.6% of the pre-MDA levels in the Central and North regions, respectively. This study showed that in filariasis endemic areas in Sarawak, anti-filarial IgG4 antibodies to BmR1, as detected by the Brugia Rapid test, were positive for one to two years after mf disappearance.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">22543621</PMID><DateCreated><Year>2012</Year><Month>04</Month><Day>30</Day></DateCreated><DateCompleted><Year>2012</Year><Month>08</Month><Day>15</Day></DateCompleted><DateRevised><Year>2015</Year><Month>11</Month><Day>19</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0127-5720</ISSN><JournalIssue CitedMedium="Internet"><Volume>29</Volume><Issue>1</Issue><PubDate><Year>2012</Year><Month>Mar</Month></PubDate></JournalIssue><Title>Tropical biomedicine</Title><ISOAbbreviation>Trop Biomed</ISOAbbreviation></Journal><ArticleTitle>Duration of detection of anti-BmR1 IgG4 antibodies after mass-drug administration (MDA) in Sarawak, Malaysia.</ArticleTitle><Pagination><MedlinePgn>191-6</MedlinePgn></Pagination><Abstract><AbstractText>The detection rates of brugian filariasis in three regions of Sarawak namely Central, North and South after three courses of mass drug administration (MDA) from year 2004 to 2006 was investigated. A recombinant BmR1 antigen-based IgG4 detection test, named Brugia Rapid and night blood smear for microfilaria (mf) detection were used. All three regions recorded a sharp fall in mf positive rates after a year post-MDA. Meanwhile Brugia Rapid positive rates declined more gradually to 3.8% and 5.6% of the pre-MDA levels in the Central and North regions, respectively. This study showed that in filariasis endemic areas in Sarawak, anti-filarial IgG4 antibodies to BmR1, as detected by the Brugia Rapid test, were positive for one to two years after mf disappearance.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Noordin</LastName><ForeName>R</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Penang, Malaysia. rahmah8485@gmail.com</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Muhi</LastName><ForeName>J</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Md Idris</LastName><ForeName>Z</ForeName><Initials>Z</Initials></Author><Author ValidYN="Y"><LastName>Arifin</LastName><ForeName>N</ForeName><Initials>N</Initials></Author><Author ValidYN="Y"><LastName>Kiyu</LastName><ForeName>A</ForeName><Initials>A</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Malaysia</Country><MedlineTA>Trop Biomed</MedlineTA><NlmUniqueID>8507086</NlmUniqueID><ISSNLinking>0127-5720</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000909">Antibodies, Helminth</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000947">Antigens, Helminth</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D005369">Filaricides</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007074">Immunoglobulin G</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D011994">Recombinant 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MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2012</Year><Month>5</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2012</Year><Month>5</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2012</Year><Month>8</Month><Day>16</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">22543621</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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