Serveur d'exploration sur le lymphœdème

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Early diagnosis and risk factors for lymphedema following lymph node dissection for gynecologic cancer.

Identifieur interne : 001D31 ( PubMed/Curation ); précédent : 001D30; suivant : 001D32

Early diagnosis and risk factors for lymphedema following lymph node dissection for gynecologic cancer.

Auteurs : Shinsuke Akita [Japon] ; Nobuyuki Mitsukawa ; Naoaki Rikihisa ; Yoshitaka Kubota ; Naoko Omori ; Akira Mitsuhashi ; Shinichi Tate ; Makio Shozu ; Kaneshige Satoh

Source :

RBID : pubmed:23357989

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Abstract

Although early diagnosis is important for selecting an effective surgical treatment for secondary lymphedema, an efficient screening test for detecting early-stage lymphedema has not yet been established. Serial changes of lymphatic function before and after lymph node dissection and risk factors for secondary lymphedema are important indicators.

DOI: 10.1097/PRS.0b013e318277870f
PubMed: 23357989

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pubmed:23357989

Le document en format XML

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<title xml:lang="en">Early diagnosis and risk factors for lymphedema following lymph node dissection for gynecologic cancer.</title>
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<name sortKey="Akita, Shinsuke" sort="Akita, Shinsuke" uniqKey="Akita S" first="Shinsuke" last="Akita">Shinsuke Akita</name>
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<nlm:affiliation>Department of Plastic, Reconstructive, and Aesthetic Surgery, Chiba University, Faculty of Medicine, Chiba City, Japan. sakita-chiba@umin.ac.jp</nlm:affiliation>
<country xml:lang="fr">Japon</country>
<wicri:regionArea>Department of Plastic, Reconstructive, and Aesthetic Surgery, Chiba University, Faculty of Medicine, Chiba City</wicri:regionArea>
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<name sortKey="Mitsukawa, Nobuyuki" sort="Mitsukawa, Nobuyuki" uniqKey="Mitsukawa N" first="Nobuyuki" last="Mitsukawa">Nobuyuki Mitsukawa</name>
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<name sortKey="Rikihisa, Naoaki" sort="Rikihisa, Naoaki" uniqKey="Rikihisa N" first="Naoaki" last="Rikihisa">Naoaki Rikihisa</name>
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<name sortKey="Kubota, Yoshitaka" sort="Kubota, Yoshitaka" uniqKey="Kubota Y" first="Yoshitaka" last="Kubota">Yoshitaka Kubota</name>
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<name sortKey="Omori, Naoko" sort="Omori, Naoko" uniqKey="Omori N" first="Naoko" last="Omori">Naoko Omori</name>
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<name sortKey="Mitsuhashi, Akira" sort="Mitsuhashi, Akira" uniqKey="Mitsuhashi A" first="Akira" last="Mitsuhashi">Akira Mitsuhashi</name>
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<name sortKey="Tate, Shinichi" sort="Tate, Shinichi" uniqKey="Tate S" first="Shinichi" last="Tate">Shinichi Tate</name>
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<name sortKey="Shozu, Makio" sort="Shozu, Makio" uniqKey="Shozu M" first="Makio" last="Shozu">Makio Shozu</name>
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<name sortKey="Rikihisa, Naoaki" sort="Rikihisa, Naoaki" uniqKey="Rikihisa N" first="Naoaki" last="Rikihisa">Naoaki Rikihisa</name>
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<name sortKey="Kubota, Yoshitaka" sort="Kubota, Yoshitaka" uniqKey="Kubota Y" first="Yoshitaka" last="Kubota">Yoshitaka Kubota</name>
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<name sortKey="Omori, Naoko" sort="Omori, Naoko" uniqKey="Omori N" first="Naoko" last="Omori">Naoko Omori</name>
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<name sortKey="Mitsuhashi, Akira" sort="Mitsuhashi, Akira" uniqKey="Mitsuhashi A" first="Akira" last="Mitsuhashi">Akira Mitsuhashi</name>
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<name sortKey="Tate, Shinichi" sort="Tate, Shinichi" uniqKey="Tate S" first="Shinichi" last="Tate">Shinichi Tate</name>
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<name sortKey="Shozu, Makio" sort="Shozu, Makio" uniqKey="Shozu M" first="Makio" last="Shozu">Makio Shozu</name>
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<title level="j">Plastic and reconstructive surgery</title>
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<term>Adult</term>
<term>Aged</term>
<term>Early Diagnosis</term>
<term>Female</term>
<term>Genital Neoplasms, Female (surgery)</term>
<term>Humans</term>
<term>Lymph Node Excision (adverse effects)</term>
<term>Lymphedema (diagnosis)</term>
<term>Lymphedema (etiology)</term>
<term>Lymphography (methods)</term>
<term>Middle Aged</term>
<term>Prospective Studies</term>
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<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Diagnostic précoce</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lymphadénectomie (effets indésirables)</term>
<term>Lymphoedème (diagnostic)</term>
<term>Lymphoedème (étiologie)</term>
<term>Lymphographie ()</term>
<term>Sujet âgé</term>
<term>Tumeurs de l'appareil génital féminin ()</term>
<term>Études prospectives</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en">
<term>Lymph Node Excision</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en">
<term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr">
<term>Lymphoedème</term>
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<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr">
<term>Lymphadénectomie</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en">
<term>Lymphedema</term>
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<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Lymphography</term>
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<keywords scheme="MESH" qualifier="surgery" xml:lang="en">
<term>Genital Neoplasms, Female</term>
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<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr">
<term>Lymphoedème</term>
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<term>Adult</term>
<term>Aged</term>
<term>Early Diagnosis</term>
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<term>Humans</term>
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<term>Adulte d'âge moyen</term>
<term>Diagnostic précoce</term>
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<term>Lymphographie</term>
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<front>
<div type="abstract" xml:lang="en">Although early diagnosis is important for selecting an effective surgical treatment for secondary lymphedema, an efficient screening test for detecting early-stage lymphedema has not yet been established. Serial changes of lymphatic function before and after lymph node dissection and risk factors for secondary lymphedema are important indicators.</div>
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<DateCreated>
<Year>2013</Year>
<Month>01</Month>
<Day>29</Day>
</DateCreated>
<DateCompleted>
<Year>2013</Year>
<Month>04</Month>
<Day>01</Day>
</DateCompleted>
<DateRevised>
<Year>2015</Year>
<Month>06</Month>
<Day>24</Day>
</DateRevised>
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<ISSN IssnType="Electronic">1529-4242</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>131</Volume>
<Issue>2</Issue>
<PubDate>
<Year>2013</Year>
<Month>Feb</Month>
</PubDate>
</JournalIssue>
<Title>Plastic and reconstructive surgery</Title>
<ISOAbbreviation>Plast. Reconstr. Surg.</ISOAbbreviation>
</Journal>
<ArticleTitle>Early diagnosis and risk factors for lymphedema following lymph node dissection for gynecologic cancer.</ArticleTitle>
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<MedlinePgn>283-90</MedlinePgn>
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<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Although early diagnosis is important for selecting an effective surgical treatment for secondary lymphedema, an efficient screening test for detecting early-stage lymphedema has not yet been established. Serial changes of lymphatic function before and after lymph node dissection and risk factors for secondary lymphedema are important indicators.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">A prospective cohort observational study was conducted with 100 consecutive gynecologic cancer patients who underwent pelvic lymph node dissection. Lymphatic function was assessed by noninvasive lymphography using indocyanine green fluorescence imaging on a routine schedule. Earliest findings after lymphadenectomy and risk factors for lower leg lymphedema were investigated.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Atypical transient dermal backflow patterns were observed in an early postoperative period in 50 cases, all of which disappeared within 3 months. Of these patterns, the splash pattern was observed in 31 patients, of which five improved to normal following a natural course. In contrast, the stardust pattern was observed in 27 patients, and none had improved with conservative therapy. Postoperative radiotherapy was a significant risk factor for the stardust pattern.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">All patients who undergo lymphadenectomy for gynecologic malignancies should be examined for secondary lower extremity lymphedema by qualitative evaluation methods on a routine schedule to determine the earliest possible diagnosis. Because the splash pattern on indocyanine green lymphography is a reversible lymphatic disorder following a natural course, surgical treatments are not recommended. The decision regarding surgical treatment can be made after observing the stardust pattern.</AbstractText>
<AbstractText Label="CLINICAL QUESTION/LEVEL OF EVIDENCE" NlmCategory="METHODS">Diagnostic, IV.</AbstractText>
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<LastName>Akita</LastName>
<ForeName>Shinsuke</ForeName>
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<Affiliation>Department of Plastic, Reconstructive, and Aesthetic Surgery, Chiba University, Faculty of Medicine, Chiba City, Japan. sakita-chiba@umin.ac.jp</Affiliation>
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<RefSource>Plast Reconstr Surg. 2013 Sep;132(3):473e-4e</RefSource>
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<RefSource>Plast Reconstr Surg. 2013 Sep;132(3):469e-71e</RefSource>
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<RefSource>Plast Reconstr Surg. 2013 Sep;132(3):472e-3e</RefSource>
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<RefSource>Plast Reconstr Surg. 2013 Feb;131(2):291-2</RefSource>
<PMID Version="1">23357990</PMID>
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<CommentsCorrections RefType="CommentIn">
<RefSource>Plast Reconstr Surg. 2013 Sep;132(3):471e-2e</RefSource>
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<MeshHeading>
<DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
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<DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
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<DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName>
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<QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName>
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<DescriptorName UI="D008220" MajorTopicYN="Y">Lymphography</DescriptorName>
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<DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
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<DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName>
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