Fully automated dual-color dual-hapten silver in situ hybridization staining for MYC amplification: a diagnostic tool for discriminating secondary angiosarcoma.
Identifieur interne : 001788 ( PubMed/Curation ); précédent : 001787; suivant : 001789Fully automated dual-color dual-hapten silver in situ hybridization staining for MYC amplification: a diagnostic tool for discriminating secondary angiosarcoma.
Auteurs : Jennifer S. Ko [États-Unis] ; Steven D. Billings ; Christopher P. Lanigan ; Darya Buehler ; Anthony P. Fernandez ; Raymond R. TubbsSource :
- Journal of cutaneous pathology [ 1600-0560 ] ; 2014.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Amplification de gène, Argent (), Femelle, Humains, Hybridation in situ (), Hémangiosarcome (anatomopathologie), Hémangiosarcome (génétique), Hémangiosarcome (métabolisme), Mâle, Protéines proto-oncogènes c-myc (génétique), Protéines proto-oncogènes c-myc (métabolisme), Sujet âgé, Sujet âgé de 80 ans ou plus, Tumeurs cutanées (anatomopathologie), Tumeurs cutanées (génétique), Tumeurs cutanées (métabolisme), Tumeurs radio-induites (anatomopathologie), Tumeurs radio-induites (génétique), Tumeurs radio-induites (métabolisme), Études rétrospectives.
- MESH :
- anatomopathologie : Hémangiosarcome, Tumeurs cutanées, Tumeurs radio-induites.
- génétique : Hémangiosarcome, Protéines proto-oncogènes c-myc, Tumeurs cutanées, Tumeurs radio-induites.
- métabolisme : Hémangiosarcome, Protéines proto-oncogènes c-myc, Tumeurs cutanées, Tumeurs radio-induites.
- Adulte, Adulte d'âge moyen, Amplification de gène, Argent, Femelle, Humains, Hybridation in situ, Mâle, Sujet âgé, Sujet âgé de 80 ans ou plus, Études rétrospectives.
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, Female, Gene Amplification, Hemangiosarcoma (genetics), Hemangiosarcoma (metabolism), Hemangiosarcoma (pathology), Humans, In Situ Hybridization (methods), Male, Middle Aged, Neoplasms, Radiation-Induced (genetics), Neoplasms, Radiation-Induced (metabolism), Neoplasms, Radiation-Induced (pathology), Proto-Oncogene Proteins c-myc (genetics), Proto-Oncogene Proteins c-myc (metabolism), Retrospective Studies, Silver (chemistry), Skin Neoplasms (genetics), Skin Neoplasms (metabolism), Skin Neoplasms (pathology).
- MESH :
- chemical , chemistry : Silver.
- chemical , genetics : Proto-Oncogene Proteins c-myc.
- genetics : Hemangiosarcoma, Neoplasms, Radiation-Induced, Skin Neoplasms.
- metabolism : Hemangiosarcoma, Neoplasms, Radiation-Induced, Proto-Oncogene Proteins c-myc, Skin Neoplasms.
- methods : In Situ Hybridization.
- pathology : Hemangiosarcoma, Neoplasms, Radiation-Induced, Skin Neoplasms.
- Adult, Aged, Aged, 80 and over, Female, Gene Amplification, Humans, Male, Middle Aged, Retrospective Studies.
Abstract
MYC amplification occurs in post-radiation and chronic lymphedema-associated secondary angiosarcoma and some primary angiosarcomas. In this study, we tested the ability of automated dual-color dual-hapten in situ hybridization (DISH) staining to discriminate secondary angiosarcoma from radiation-associated atypical vascular lesions (AVL), and to correlate with fluorescence in situ hybridization (FISH) for MYC amplification.
DOI: 10.1111/cup.12278
PubMed: 24329959
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001788
Links to Exploration step
pubmed:24329959Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Fully automated dual-color dual-hapten silver in situ hybridization staining for MYC amplification: a diagnostic tool for discriminating secondary angiosarcoma.</title><author><name sortKey="Ko, Jennifer S" sort="Ko, Jennifer S" uniqKey="Ko J" first="Jennifer S" last="Ko">Jennifer S. Ko</name><affiliation wicri:level="1"><nlm:affiliation>Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH</wicri:regionArea></affiliation></author><author><name sortKey="Billings, Steven D" sort="Billings, Steven D" uniqKey="Billings S" first="Steven D" last="Billings">Steven D. Billings</name></author><author><name sortKey="Lanigan, Christopher P" sort="Lanigan, Christopher P" uniqKey="Lanigan C" first="Christopher P" last="Lanigan">Christopher P. Lanigan</name></author><author><name sortKey="Buehler, Darya" sort="Buehler, Darya" uniqKey="Buehler D" first="Darya" last="Buehler">Darya Buehler</name></author><author><name sortKey="Fernandez, Anthony P" sort="Fernandez, Anthony P" uniqKey="Fernandez A" first="Anthony P" last="Fernandez">Anthony P. Fernandez</name></author><author><name sortKey="Tubbs, Raymond R" sort="Tubbs, Raymond R" uniqKey="Tubbs R" first="Raymond R" last="Tubbs">Raymond R. Tubbs</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:24329959</idno><idno type="pmid">24329959</idno><idno type="doi">10.1111/cup.12278</idno><idno type="wicri:Area/PubMed/Corpus">001788</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001788</idno><idno type="wicri:Area/PubMed/Curation">001788</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001788</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Fully automated dual-color dual-hapten silver in situ hybridization staining for MYC amplification: a diagnostic tool for discriminating secondary angiosarcoma.</title><author><name sortKey="Ko, Jennifer S" sort="Ko, Jennifer S" uniqKey="Ko J" first="Jennifer S" last="Ko">Jennifer S. Ko</name><affiliation wicri:level="1"><nlm:affiliation>Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH</wicri:regionArea></affiliation></author><author><name sortKey="Billings, Steven D" sort="Billings, Steven D" uniqKey="Billings S" first="Steven D" last="Billings">Steven D. Billings</name></author><author><name sortKey="Lanigan, Christopher P" sort="Lanigan, Christopher P" uniqKey="Lanigan C" first="Christopher P" last="Lanigan">Christopher P. Lanigan</name></author><author><name sortKey="Buehler, Darya" sort="Buehler, Darya" uniqKey="Buehler D" first="Darya" last="Buehler">Darya Buehler</name></author><author><name sortKey="Fernandez, Anthony P" sort="Fernandez, Anthony P" uniqKey="Fernandez A" first="Anthony P" last="Fernandez">Anthony P. Fernandez</name></author><author><name sortKey="Tubbs, Raymond R" sort="Tubbs, Raymond R" uniqKey="Tubbs R" first="Raymond R" last="Tubbs">Raymond R. Tubbs</name></author></analytic><series><title level="j">Journal of cutaneous pathology</title><idno type="eISSN">1600-0560</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Female</term><term>Gene Amplification</term><term>Hemangiosarcoma (genetics)</term><term>Hemangiosarcoma (metabolism)</term><term>Hemangiosarcoma (pathology)</term><term>Humans</term><term>In Situ Hybridization (methods)</term><term>Male</term><term>Middle Aged</term><term>Neoplasms, Radiation-Induced (genetics)</term><term>Neoplasms, Radiation-Induced (metabolism)</term><term>Neoplasms, Radiation-Induced (pathology)</term><term>Proto-Oncogene Proteins c-myc (genetics)</term><term>Proto-Oncogene Proteins c-myc (metabolism)</term><term>Retrospective Studies</term><term>Silver (chemistry)</term><term>Skin Neoplasms (genetics)</term><term>Skin Neoplasms (metabolism)</term><term>Skin Neoplasms (pathology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Amplification de gène</term><term>Argent ()</term><term>Femelle</term><term>Humains</term><term>Hybridation in situ ()</term><term>Hémangiosarcome (anatomopathologie)</term><term>Hémangiosarcome (génétique)</term><term>Hémangiosarcome (métabolisme)</term><term>Mâle</term><term>Protéines proto-oncogènes c-myc (génétique)</term><term>Protéines proto-oncogènes c-myc (métabolisme)</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Tumeurs cutanées (anatomopathologie)</term><term>Tumeurs cutanées (génétique)</term><term>Tumeurs cutanées (métabolisme)</term><term>Tumeurs radio-induites (anatomopathologie)</term><term>Tumeurs radio-induites (génétique)</term><term>Tumeurs radio-induites (métabolisme)</term><term>Études rétrospectives</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Silver</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Proto-Oncogene Proteins c-myc</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Hémangiosarcome</term><term>Tumeurs cutanées</term><term>Tumeurs radio-induites</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Hemangiosarcoma</term><term>Neoplasms, Radiation-Induced</term><term>Skin Neoplasms</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Hémangiosarcome</term><term>Protéines proto-oncogènes c-myc</term><term>Tumeurs cutanées</term><term>Tumeurs radio-induites</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Hemangiosarcoma</term><term>Neoplasms, Radiation-Induced</term><term>Proto-Oncogene Proteins c-myc</term><term>Skin Neoplasms</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>In Situ Hybridization</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Hémangiosarcome</term><term>Protéines proto-oncogènes c-myc</term><term>Tumeurs cutanées</term><term>Tumeurs radio-induites</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Hemangiosarcoma</term><term>Neoplasms, Radiation-Induced</term><term>Skin Neoplasms</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Female</term><term>Gene Amplification</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Retrospective Studies</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Amplification de gène</term><term>Argent</term><term>Femelle</term><term>Humains</term><term>Hybridation in situ</term><term>Mâle</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Études rétrospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">MYC amplification occurs in post-radiation and chronic lymphedema-associated secondary angiosarcoma and some primary angiosarcomas. In this study, we tested the ability of automated dual-color dual-hapten in situ hybridization (DISH) staining to discriminate secondary angiosarcoma from radiation-associated atypical vascular lesions (AVL), and to correlate with fluorescence in situ hybridization (FISH) for MYC amplification.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24329959</PMID><DateCreated><Year>2014</Year><Month>03</Month><Day>04</Day></DateCreated><DateCompleted><Year>2014</Year><Month>10</Month><Day>20</Day></DateCompleted><DateRevised><Year>2014</Year><Month>03</Month><Day>04</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1600-0560</ISSN><JournalIssue CitedMedium="Internet"><Volume>41</Volume><Issue>3</Issue><PubDate><Year>2014</Year><Month>Mar</Month></PubDate></JournalIssue><Title>Journal of cutaneous pathology</Title><ISOAbbreviation>J. Cutan. Pathol.</ISOAbbreviation></Journal><ArticleTitle>Fully automated dual-color dual-hapten silver in situ hybridization staining for MYC amplification: a diagnostic tool for discriminating secondary angiosarcoma.</ArticleTitle><Pagination><MedlinePgn>286-92</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1111/cup.12278</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">MYC amplification occurs in post-radiation and chronic lymphedema-associated secondary angiosarcoma and some primary angiosarcomas. In this study, we tested the ability of automated dual-color dual-hapten in situ hybridization (DISH) staining to discriminate secondary angiosarcoma from radiation-associated atypical vascular lesions (AVL), and to correlate with fluorescence in situ hybridization (FISH) for MYC amplification.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Cases of secondary angiosarcoma, including 11 biopsies and 3 excisions from 11 patients, and 5 AVL biopsies from 5 patients, were examined by FISH and DISH. DISH staining was performed using the Dual Color Open Probe software on a Ventana Benchmark XT automated slide stainer. Metallic black silver (MYC) and reference CHR8 red signals were qualitatively and semi-quantitatively enumerated for tumor nuclei. Small and large clusters of silver signals were recorded as 6 or 12 signals, respectively. MYC amplification was defined as MYC/CHR8 ratio >2.0.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Where tissue was available for both DISH and FISH, all secondary angiosarcoma cases showed MYC amplification (11/11 = 100%) by both DISH and FISH. All AVL were negative for MYC amplification by both techniques (0/5 = 0%).</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">In the current cohort, use of DISH identified all MYC amplified cases, and distinguished secondary angiosarcoma from AVL. DISH staining may be useful in distinguishing secondary angiosarcoma from AVL in challenging cases.</AbstractText><CopyrightInformation>© 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ko</LastName><ForeName>Jennifer S</ForeName><Initials>JS</Initials><AffiliationInfo><Affiliation>Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Billings</LastName><ForeName>Steven D</ForeName><Initials>SD</Initials></Author><Author ValidYN="Y"><LastName>Lanigan</LastName><ForeName>Christopher P</ForeName><Initials>CP</Initials></Author><Author ValidYN="Y"><LastName>Buehler</LastName><ForeName>Darya</ForeName><Initials>D</Initials></Author><Author ValidYN="Y"><LastName>Fernandez</LastName><ForeName>Anthony P</ForeName><Initials>AP</Initials></Author><Author ValidYN="Y"><LastName>Tubbs</LastName><ForeName>Raymond R</ForeName><Initials>RR</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2014</Year><Month>01</Month><Day>22</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Cutan Pathol</MedlineTA><NlmUniqueID>0425124</NlmUniqueID><ISSNLinking>0303-6987</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C489427">MYC protein, human</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D016271">Proto-Oncogene Proteins c-myc</NameOfSubstance></Chemical><Chemical><RegistryNumber>3M4G523W1G</RegistryNumber><NameOfSubstance UI="D012834">Silver</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005784" MajorTopicYN="Y">Gene Amplification</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006394" MajorTopicYN="Y">Hemangiosarcoma</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017403" MajorTopicYN="N">In Situ Hybridization</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009381" MajorTopicYN="Y">Neoplasms, Radiation-Induced</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016271" MajorTopicYN="Y">Proto-Oncogene Proteins c-myc</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012834" MajorTopicYN="N">Silver</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012878" MajorTopicYN="Y">Skin Neoplasms</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">MYC</Keyword><Keyword MajorTopicYN="N">atypical vascular lesions</Keyword><Keyword MajorTopicYN="N">in situ hybridization</Keyword><Keyword MajorTopicYN="N">secondary angiosarcoma</Keyword><Keyword MajorTopicYN="N">soft tissue tumors</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2013</Year><Month>08</Month><Day>19</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2013</Year><Month>11</Month><Day>14</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2013</Year><Month>11</Month><Day>17</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2013</Year><Month>12</Month><Day>17</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2013</Year><Month>12</Month><Day>18</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2014</Year><Month>10</Month><Day>21</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">24329959</ArticleId><ArticleId IdType="doi">10.1111/cup.12278</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001788 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 001788 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= PubMed
|étape= Curation
|type= RBID
|clé= pubmed:24329959
|texte= Fully automated dual-color dual-hapten silver in situ hybridization staining for MYC amplification: a diagnostic tool for discriminating secondary angiosarcoma.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:24329959" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |