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Feasibility study on the effectiveness of Goreisan-based Kampo therapy for lower abdominal lymphedema after retroperitoneal lymphadenectomy via extraperitoneal approach.

Identifieur interne : 000E73 ( PubMed/Curation ); précédent : 000E72; suivant : 000E74

Feasibility study on the effectiveness of Goreisan-based Kampo therapy for lower abdominal lymphedema after retroperitoneal lymphadenectomy via extraperitoneal approach.

Auteurs : Shinichi Komiyama [Japon] ; Chiaki Takeya [Japon] ; Rena Takahashi [Japon] ; Yasuhiro Yamamoto [Japon] ; Kaneyuki Kubushiro [Japon]

Source :

RBID : pubmed:26013736

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English descriptors

Abstract

To evaluate the efficacy and safety of Kampo therapy based on Goreisan for lower abdominal lymphedema after surgical treatment of endometrial cancer or cervical cancer.

DOI: 10.1111/jog.12721
PubMed: 26013736

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pubmed:26013736

Le document en format XML

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<name sortKey="Takahashi, Rena" sort="Takahashi, Rena" uniqKey="Takahashi R" first="Rena" last="Takahashi">Rena Takahashi</name>
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<name sortKey="Yamamoto, Yasuhiro" sort="Yamamoto, Yasuhiro" uniqKey="Yamamoto Y" first="Yasuhiro" last="Yamamoto">Yasuhiro Yamamoto</name>
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<title xml:lang="en">Feasibility study on the effectiveness of Goreisan-based Kampo therapy for lower abdominal lymphedema after retroperitoneal lymphadenectomy via extraperitoneal approach.</title>
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<name sortKey="Takahashi, Rena" sort="Takahashi, Rena" uniqKey="Takahashi R" first="Rena" last="Takahashi">Rena Takahashi</name>
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<name sortKey="Yamamoto, Yasuhiro" sort="Yamamoto, Yasuhiro" uniqKey="Yamamoto Y" first="Yasuhiro" last="Yamamoto">Yasuhiro Yamamoto</name>
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<name sortKey="Kubushiro, Kaneyuki" sort="Kubushiro, Kaneyuki" uniqKey="Kubushiro K" first="Kaneyuki" last="Kubushiro">Kaneyuki Kubushiro</name>
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<title level="j">The journal of obstetrics and gynaecology research</title>
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<term>Adult</term>
<term>Drainage</term>
<term>Endometrial Neoplasms (surgery)</term>
<term>Feasibility Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Lymph Node Excision (adverse effects)</term>
<term>Lymph Node Excision (methods)</term>
<term>Lymphedema (etiology)</term>
<term>Lymphedema (therapy)</term>
<term>Medicine, Chinese Traditional (methods)</term>
<term>Medicine, Kampo (methods)</term>
<term>Middle Aged</term>
<term>Physical Therapy Modalities</term>
<term>Postoperative Complications (etiology)</term>
<term>Postoperative Complications (therapy)</term>
<term>Treatment Outcome</term>
<term>Uterine Cervical Neoplasms (surgery)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Complications postopératoires ()</term>
<term>Complications postopératoires (étiologie)</term>
<term>Drainage</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lymphadénectomie ()</term>
<term>Lymphadénectomie (effets indésirables)</term>
<term>Lymphoedème ()</term>
<term>Lymphoedème (étiologie)</term>
<term>Médecine kampo ()</term>
<term>Médecine traditionnelle chinoise ()</term>
<term>Résultat thérapeutique</term>
<term>Techniques de physiothérapie</term>
<term>Tumeurs de l'endomètre ()</term>
<term>Tumeurs du col de l'utérus ()</term>
<term>Études de faisabilité</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en">
<term>Lymph Node Excision</term>
</keywords>
<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr">
<term>Lymphadénectomie</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en">
<term>Lymphedema</term>
<term>Postoperative Complications</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Lymph Node Excision</term>
<term>Medicine, Chinese Traditional</term>
<term>Medicine, Kampo</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en">
<term>Endometrial Neoplasms</term>
<term>Uterine Cervical Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en">
<term>Lymphedema</term>
<term>Postoperative Complications</term>
</keywords>
<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr">
<term>Complications postopératoires</term>
<term>Lymphoedème</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Adult</term>
<term>Drainage</term>
<term>Feasibility Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Middle Aged</term>
<term>Physical Therapy Modalities</term>
<term>Treatment Outcome</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Complications postopératoires</term>
<term>Drainage</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lymphadénectomie</term>
<term>Lymphoedème</term>
<term>Médecine kampo</term>
<term>Médecine traditionnelle chinoise</term>
<term>Résultat thérapeutique</term>
<term>Techniques de physiothérapie</term>
<term>Tumeurs de l'endomètre</term>
<term>Tumeurs du col de l'utérus</term>
<term>Études de faisabilité</term>
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<front>
<div type="abstract" xml:lang="en">To evaluate the efficacy and safety of Kampo therapy based on Goreisan for lower abdominal lymphedema after surgical treatment of endometrial cancer or cervical cancer.</div>
</front>
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<pubmed>
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<PMID Version="1">26013736</PMID>
<DateCreated>
<Year>2015</Year>
<Month>09</Month>
<Day>08</Day>
</DateCreated>
<DateCompleted>
<Year>2016</Year>
<Month>12</Month>
<Day>13</Day>
</DateCompleted>
<DateRevised>
<Year>2016</Year>
<Month>12</Month>
<Day>30</Day>
</DateRevised>
<Article PubModel="Print-Electronic">
<Journal>
<ISSN IssnType="Electronic">1447-0756</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>41</Volume>
<Issue>9</Issue>
<PubDate>
<Year>2015</Year>
<Month>Sep</Month>
</PubDate>
</JournalIssue>
<Title>The journal of obstetrics and gynaecology research</Title>
<ISOAbbreviation>J. Obstet. Gynaecol. Res.</ISOAbbreviation>
</Journal>
<ArticleTitle>Feasibility study on the effectiveness of Goreisan-based Kampo therapy for lower abdominal lymphedema after retroperitoneal lymphadenectomy via extraperitoneal approach.</ArticleTitle>
<Pagination>
<MedlinePgn>1449-56</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1111/jog.12721</ELocationID>
<Abstract>
<AbstractText Label="AIM" NlmCategory="OBJECTIVE">To evaluate the efficacy and safety of Kampo therapy based on Goreisan for lower abdominal lymphedema after surgical treatment of endometrial cancer or cervical cancer.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Radical surgery, including retroperitoneal lymphadenectomy, was performed for endometrial cancer and cervical cancer. After surgery, Kampo therapy based on Goreisan and integrated physical therapy were provided for patients with lower abdominal lymphedema, especially lymphedema affecting the pubic-inguinal-vulval region. Goreisan (7.5 g/day) was given orally three times a day (tds). If a significant response was not observed, Saireito (9 g/day; 3 g tds) or Gosyajinkigan (7.5 g/day; 2.5 g tds) was administered concomitantly.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">A total of 21 patients received treatment. The response rate to Goreisan monotherapy was 78%, with 22% being non-responders. Median reduction of abdominal circumference was 2.1cm (95% CI 1.3-2.85). When Goreisan was combined with another Kampo agent, the response rate was 92% and the non-response rate was 8%. The median reduction of the abdominal circumference was 2.85 cm (95% CI: 2.25-3.3). In particular, concomitant Goreisan and Saireito therapy achieved satisfactory results. No severe adverse reactions occurred.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Goreisan-based Kampo therapy might be effective and safe for lower abdominal lymphedema after retroperitoneal lymphadenectomy. We will perform a prospective control study in the near future.</AbstractText>
<CopyrightInformation>© 2015 Japan Society of Obstetrics and Gynecology.</CopyrightInformation>
</Abstract>
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<LastName>Komiyama</LastName>
<ForeName>Shinichi</ForeName>
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<Affiliation>Department of Gynecology, Toho University Ohashi Medical Center, Tokyo, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Takeya</LastName>
<ForeName>Chiaki</ForeName>
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<Affiliation>Department of Gynecology, Toho University Ohashi Medical Center, Tokyo, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Takahashi</LastName>
<ForeName>Rena</ForeName>
<Initials>R</Initials>
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<Affiliation>Department of Gynecology, Toho University Ohashi Medical Center, Tokyo, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Yamamoto</LastName>
<ForeName>Yasuhiro</ForeName>
<Initials>Y</Initials>
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<Affiliation>Department of Gynecology, Toho University Ohashi Medical Center, Tokyo, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Kubushiro</LastName>
<ForeName>Kaneyuki</ForeName>
<Initials>K</Initials>
<AffiliationInfo>
<Affiliation>Department of Gynecology, Toho University Ohashi Medical Center, Tokyo, Japan.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList>
<PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
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<Year>2015</Year>
<Month>05</Month>
<Day>25</Day>
</ArticleDate>
</Article>
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<Country>Australia</Country>
<MedlineTA>J Obstet Gynaecol Res</MedlineTA>
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<ISSNLinking>1341-8076</ISSNLinking>
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<DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
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<DescriptorName UI="D004322" MajorTopicYN="N">Drainage</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D016889" MajorTopicYN="N">Endometrial Neoplasms</DescriptorName>
<QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName>
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<DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
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<MeshHeading>
<DescriptorName UI="D008516" MajorTopicYN="N">Medicine, Chinese Traditional</DescriptorName>
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<MeshHeading>
<DescriptorName UI="D020835" MajorTopicYN="N">Medicine, Kampo</DescriptorName>
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<MeshHeading>
<DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
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<DescriptorName UI="D026741" MajorTopicYN="Y">Physical Therapy Modalities</DescriptorName>
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<MeshHeading>
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<MeshHeading>
<DescriptorName UI="D016896" MajorTopicYN="N">Treatment Outcome</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D002583" MajorTopicYN="N">Uterine Cervical Neoplasms</DescriptorName>
<QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM">
<Keyword MajorTopicYN="N">Goreisan</Keyword>
<Keyword MajorTopicYN="N">Kampo</Keyword>
<Keyword MajorTopicYN="N">lower abdominal lymphedema</Keyword>
<Keyword MajorTopicYN="N">retroperitoneal lymphadenectomy</Keyword>
<Keyword MajorTopicYN="N">uterine cancer</Keyword>
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</MedlineCitation>
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<Year>2015</Year>
<Month>02</Month>
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