[Prophylactic axillary radiotherapy for breast cancer].
Identifieur interne : 000E49 ( PubMed/Curation ); précédent : 000E48; suivant : 000E50[Prophylactic axillary radiotherapy for breast cancer].
Auteurs : S. Rivera [France] ; G. Louvel [France] ; E. Rivin Del Campo [France] ; A. Boros [France] ; H. Oueslati [France] ; É Deutsch [France]Source :
- Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique [ 1769-6658 ] ; 2015.
Descripteurs français
- KwdFr :
- MESH :
- anatomopathologie : Tumeurs du sein.
- radiothérapie : Tumeurs du sein.
- Aisselle, Arbres de décision, Femelle, Humains, Irradiation ganglionnaire, Récidive tumorale locale, Stade de la tumeur, Tumeurs du sein.
English descriptors
- KwdEn :
- MESH :
- pathology : Breast Neoplasms.
- prevention & control : Breast Neoplasms, Neoplasm Recurrence, Local.
- radiotherapy : Breast Neoplasms.
- Axilla, Decision Trees, Female, Humans, Lymphatic Irradiation, Neoplasm Staging.
Abstract
Adjuvant radiotherapy, after breast conserving surgery or mastectomy for breast cancer, improves overall survival while decreasing the risk of recurrence. However, prophylactic postoperative radiotherapy of locoregional lymph nodes for breast cancer, particularly of the axillary region, is still controversial since the benefits and the risks due to axillary irradiation have not been well defined. To begin with, when performing conformal radiotherapy, volume definition is crucial for the analysis of the risk-benefit balance of any radiation treatment. Definition and contouring of the axillary lymph node region is discussed in this work, as per the recommendations of the European Society for Radiotherapy and Oncology (ESTRO). Axillary recurrences are rare, and the recent trend leads toward less aggressive surgery with regard to the axilla. In this literature review we present the data that lead us to avoid adjuvant axillary radiotherapy in pN0, pN0i+ and pN1mi patients even without axillary clearance and to perform it in some other situations. Finally, we propose an update about the potential toxicity of adjuvant axillary irradiation, which is essential for therapeutic decision-making based on current evidence, and to guide us in the evolution of our techniques and indications of axillary radiotherapy.
DOI: 10.1016/j.canrad.2015.05.001
PubMed: 26044178
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pubmed:26044178Le document en format XML
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<term>Decision Trees</term>
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<front><div type="abstract" xml:lang="en">Adjuvant radiotherapy, after breast conserving surgery or mastectomy for breast cancer, improves overall survival while decreasing the risk of recurrence. However, prophylactic postoperative radiotherapy of locoregional lymph nodes for breast cancer, particularly of the axillary region, is still controversial since the benefits and the risks due to axillary irradiation have not been well defined. To begin with, when performing conformal radiotherapy, volume definition is crucial for the analysis of the risk-benefit balance of any radiation treatment. Definition and contouring of the axillary lymph node region is discussed in this work, as per the recommendations of the European Society for Radiotherapy and Oncology (ESTRO). Axillary recurrences are rare, and the recent trend leads toward less aggressive surgery with regard to the axilla. In this literature review we present the data that lead us to avoid adjuvant axillary radiotherapy in pN0, pN0i+ and pN1mi patients even without axillary clearance and to perform it in some other situations. Finally, we propose an update about the potential toxicity of adjuvant axillary irradiation, which is essential for therapeutic decision-making based on current evidence, and to guide us in the evolution of our techniques and indications of axillary radiotherapy.</div>
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