A palm-sized high-sensitivity near-infrared fluorescence imager for laparotomy surgery.
Identifieur interne : 000B07 ( PubMed/Curation ); précédent : 000B06; suivant : 000B08A palm-sized high-sensitivity near-infrared fluorescence imager for laparotomy surgery.
Auteurs : Paul Dorval [France] ; Norman Mangeret [France] ; Stephanie Guillermet [France] ; Ihab Atallah [France] ; Christian Righini [France] ; Gabriele Barabino [France] ; Jean-Luc Coll [France] ; Philippe Rizo [France] ; Patrick Poulet [France]Source :
- Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) [ 1724-191X ] ; 2016.
Descripteurs français
- KwdFr :
- Animaux, Chirurgie assistée par ordinateur (instrumentation), Colorants fluorescents (), Conception d'appareillage, Diagnostic par imagerie (), Diagnostic par imagerie (instrumentation), Femelle, Fibres optiques, Fluorescence, Humains, Hépatectomie, Laparotomie (), Laparotomie (instrumentation), Limite de détection, Lymphoedème (), Lymphoedème (anatomopathologie), Lymphoedème (diagnostic), Miniaturisation, Polymères (), Reproductibilité des résultats, Souris, Souris nude, Spectroscopie proche infrarouge (), Transplantation tumorale, Tumeurs colorectales (), Tumeurs colorectales (anatomopathologie), Tumeurs colorectales (diagnostic), Tumeurs de la tête et du cou (), Tumeurs de la tête et du cou (anatomopathologie), Tumeurs de la tête et du cou (diagnostic), Tumeurs du foie (), Tumeurs du foie (anatomopathologie), Tumeurs du foie (diagnostic), Vert indocyanine ().
- MESH :
- anatomopathologie : Lymphoedème, Tumeurs colorectales, Tumeurs de la tête et du cou, Tumeurs du foie.
- diagnostic : Lymphoedème, Tumeurs colorectales, Tumeurs de la tête et du cou, Tumeurs du foie.
- Animaux, Chirurgie assistée par ordinateur, Colorants fluorescents, Conception d'appareillage, Diagnostic par imagerie, Femelle, Fibres optiques, Fluorescence, Humains, Hépatectomie, Laparotomie, Limite de détection, Lymphoedème, Miniaturisation, Polymères, Reproductibilité des résultats, Souris, Souris nude, Spectroscopie proche infrarouge, Transplantation tumorale, Tumeurs colorectales, Tumeurs de la tête et du cou, Tumeurs du foie, Vert indocyanine.
English descriptors
- KwdEn :
- Animals, Colorectal Neoplasms (diagnosis), Colorectal Neoplasms (pathology), Colorectal Neoplasms (surgery), Diagnostic Imaging (instrumentation), Diagnostic Imaging (methods), Equipment Design, Female, Fluorescence, Fluorescent Dyes (chemistry), Head and Neck Neoplasms (diagnosis), Head and Neck Neoplasms (pathology), Head and Neck Neoplasms (surgery), Hepatectomy, Humans, Indocyanine Green (chemistry), Laparotomy (instrumentation), Laparotomy (methods), Limit of Detection, Liver Neoplasms (diagnosis), Liver Neoplasms (pathology), Liver Neoplasms (surgery), Lymphedema (diagnosis), Lymphedema (pathology), Lymphedema (surgery), Mice, Mice, Nude, Miniaturization, Neoplasm Transplantation, Optical Fibers, Polymers (chemistry), Reproducibility of Results, Spectroscopy, Near-Infrared (methods), Surgery, Computer-Assisted (instrumentation).
- MESH :
- chemical , chemistry : Fluorescent Dyes, Indocyanine Green, Polymers.
- diagnosis : Colorectal Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lymphedema.
- instrumentation : Diagnostic Imaging, Laparotomy, Surgery, Computer-Assisted.
- methods : Diagnostic Imaging, Laparotomy, Spectroscopy, Near-Infrared.
- pathology : Colorectal Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lymphedema.
- surgery : Colorectal Neoplasms, Head and Neck Neoplasms, Liver Neoplasms, Lymphedema.
- Animals, Equipment Design, Female, Fluorescence, Hepatectomy, Humans, Limit of Detection, Mice, Mice, Nude, Miniaturization, Neoplasm Transplantation, Optical Fibers, Reproducibility of Results.
Abstract
In laparotomy surgery guided by near-infrared fluorescence imaging, the access to the field of operation is limited by the illumination and/or the imaging field. The side of cavities or organs such as the liver or the heart cannot be examined with the systems available on the market, which are too large and too heavy. In this article, we describe and evaluate a palm sized probe, whose properties, weight, size and sensitivity are adapted for guiding laparotomy surgery. Different experiments have been performed to determine its main characteristics, both on the illumination and imaging sides. The device has been tested for fluorescent molecular probe imaging in preclinical procedures, to prove its ability to be used in cancer nodule detection during surgery. This system is now CE certified for clinical procedures and Indocyanine Green imaging has been performed during clinical investigations: lymphedema and surgical resection of liver metastases of colorectal cancers.
DOI: 10.1016/j.ejmp.2015.11.006
PubMed: 26654116
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Electronic address: paul.dorval@live.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie, UMR 7357, Fédération de Médecine Translationnelle de Strasbourg, Université de Strasbourg/CNRS, 67412 Illkirch, France; Fluoptics, 38040 Grenoble</wicri:regionArea></affiliation></author><author><name sortKey="Mangeret, Norman" sort="Mangeret, Norman" uniqKey="Mangeret N" first="Norman" last="Mangeret">Norman Mangeret</name><affiliation wicri:level="1"><nlm:affiliation>Fluoptics, 38040 Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Fluoptics, 38040 Grenoble</wicri:regionArea></affiliation></author><author><name sortKey="Guillermet, Stephanie" sort="Guillermet, Stephanie" uniqKey="Guillermet S" first="Stephanie" last="Guillermet">Stephanie Guillermet</name><affiliation wicri:level="1"><nlm:affiliation>Fluoptics, 38040 Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Fluoptics, 38040 Grenoble</wicri:regionArea></affiliation></author><author><name sortKey="Atallah, Ihab" sort="Atallah, Ihab" uniqKey="Atallah I" first="Ihab" last="Atallah">Ihab Atallah</name><affiliation wicri:level="1"><nlm:affiliation>Institut Albert Bonniot, U-823, Université Joseph Fourier/INSERM, 38000 Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Institut Albert Bonniot, U-823, Université Joseph Fourier/INSERM, 38000 Grenoble</wicri:regionArea></affiliation></author><author><name sortKey="Righini, Christian" sort="Righini, Christian" uniqKey="Righini C" first="Christian" last="Righini">Christian Righini</name><affiliation wicri:level="1"><nlm:affiliation>Institut Albert Bonniot, U-823, Université Joseph Fourier/INSERM, 38000 Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Institut Albert Bonniot, U-823, Université Joseph Fourier/INSERM, 38000 Grenoble</wicri:regionArea></affiliation></author><author><name sortKey="Barabino, Gabriele" sort="Barabino, Gabriele" uniqKey="Barabino G" first="Gabriele" last="Barabino">Gabriele Barabino</name><affiliation wicri:level="1"><nlm:affiliation>Centre Hospilato-Universitaire de Saint-Etienne, 42000 Saint-Etienne, France. Electronic address: gabriele.barabino@chu-st-etienne.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Centre Hospilato-Universitaire de Saint-Etienne, 42000 Saint-Etienne</wicri:regionArea></affiliation></author><author><name sortKey="Coll, Jean Luc" sort="Coll, Jean Luc" uniqKey="Coll J" first="Jean-Luc" last="Coll">Jean-Luc Coll</name><affiliation wicri:level="1"><nlm:affiliation>Institut Albert Bonniot, U-823, Université Joseph Fourier/INSERM, 38000 Grenoble, France. Electronic address: jean-luc.coll@ujf-grenoble.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Institut Albert Bonniot, U-823, Université Joseph Fourier/INSERM, 38000 Grenoble</wicri:regionArea></affiliation></author><author><name sortKey="Rizo, Philippe" sort="Rizo, Philippe" uniqKey="Rizo P" first="Philippe" last="Rizo">Philippe Rizo</name><affiliation wicri:level="1"><nlm:affiliation>Fluoptics, 38040 Grenoble, France; CEA-LETI, Minatec, 38054 Grenoble, France. Electronic address: philippe.rizo@fluoptics.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Fluoptics, 38040 Grenoble, France; CEA-LETI, Minatec, 38054 Grenoble</wicri:regionArea></affiliation></author><author><name sortKey="Poulet, Patrick" sort="Poulet, Patrick" uniqKey="Poulet P" first="Patrick" last="Poulet">Patrick Poulet</name><affiliation wicri:level="1"><nlm:affiliation>Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie, UMR 7357, Fédération de Médecine Translationnelle de Strasbourg, Université de Strasbourg/CNRS, 67412 Illkirch, France. Electronic address: p.poulet@unistra.fr.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie, UMR 7357, Fédération de Médecine Translationnelle de Strasbourg, Université de Strasbourg/CNRS, 67412 Illkirch</wicri:regionArea></affiliation></author></analytic><series><title level="j">Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)</title><idno type="eISSN">1724-191X</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Colorectal Neoplasms (diagnosis)</term><term>Colorectal Neoplasms (pathology)</term><term>Colorectal Neoplasms (surgery)</term><term>Diagnostic Imaging (instrumentation)</term><term>Diagnostic Imaging (methods)</term><term>Equipment Design</term><term>Female</term><term>Fluorescence</term><term>Fluorescent Dyes (chemistry)</term><term>Head and Neck Neoplasms (diagnosis)</term><term>Head and Neck Neoplasms (pathology)</term><term>Head and Neck Neoplasms (surgery)</term><term>Hepatectomy</term><term>Humans</term><term>Indocyanine Green (chemistry)</term><term>Laparotomy (instrumentation)</term><term>Laparotomy (methods)</term><term>Limit of Detection</term><term>Liver Neoplasms (diagnosis)</term><term>Liver Neoplasms (pathology)</term><term>Liver Neoplasms (surgery)</term><term>Lymphedema (diagnosis)</term><term>Lymphedema (pathology)</term><term>Lymphedema (surgery)</term><term>Mice</term><term>Mice, Nude</term><term>Miniaturization</term><term>Neoplasm Transplantation</term><term>Optical Fibers</term><term>Polymers (chemistry)</term><term>Reproducibility of Results</term><term>Spectroscopy, Near-Infrared (methods)</term><term>Surgery, Computer-Assisted (instrumentation)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Chirurgie assistée par ordinateur (instrumentation)</term><term>Colorants fluorescents ()</term><term>Conception d'appareillage</term><term>Diagnostic par imagerie ()</term><term>Diagnostic par imagerie (instrumentation)</term><term>Femelle</term><term>Fibres optiques</term><term>Fluorescence</term><term>Humains</term><term>Hépatectomie</term><term>Laparotomie ()</term><term>Laparotomie (instrumentation)</term><term>Limite de détection</term><term>Lymphoedème ()</term><term>Lymphoedème (anatomopathologie)</term><term>Lymphoedème (diagnostic)</term><term>Miniaturisation</term><term>Polymères ()</term><term>Reproductibilité des résultats</term><term>Souris</term><term>Souris nude</term><term>Spectroscopie proche infrarouge ()</term><term>Transplantation tumorale</term><term>Tumeurs colorectales ()</term><term>Tumeurs colorectales (anatomopathologie)</term><term>Tumeurs colorectales (diagnostic)</term><term>Tumeurs de la tête et du cou ()</term><term>Tumeurs de la tête et du cou (anatomopathologie)</term><term>Tumeurs de la tête et du cou (diagnostic)</term><term>Tumeurs du foie ()</term><term>Tumeurs du foie (anatomopathologie)</term><term>Tumeurs du foie (diagnostic)</term><term>Vert indocyanine ()</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Fluorescent Dyes</term><term>Indocyanine Green</term><term>Polymers</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Lymphoedème</term><term>Tumeurs colorectales</term><term>Tumeurs de la tête et du cou</term><term>Tumeurs du foie</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Colorectal Neoplasms</term><term>Head and Neck Neoplasms</term><term>Liver Neoplasms</term><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Lymphoedème</term><term>Tumeurs colorectales</term><term>Tumeurs de la tête et du cou</term><term>Tumeurs du foie</term></keywords><keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Diagnostic Imaging</term><term>Laparotomy</term><term>Surgery, Computer-Assisted</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Diagnostic Imaging</term><term>Laparotomy</term><term>Spectroscopy, Near-Infrared</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Colorectal Neoplasms</term><term>Head and Neck Neoplasms</term><term>Liver Neoplasms</term><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Colorectal Neoplasms</term><term>Head and Neck Neoplasms</term><term>Liver Neoplasms</term><term>Lymphedema</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Equipment Design</term><term>Female</term><term>Fluorescence</term><term>Hepatectomy</term><term>Humans</term><term>Limit of Detection</term><term>Mice</term><term>Mice, Nude</term><term>Miniaturization</term><term>Neoplasm Transplantation</term><term>Optical Fibers</term><term>Reproducibility of Results</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Chirurgie assistée par ordinateur</term><term>Colorants fluorescents</term><term>Conception d'appareillage</term><term>Diagnostic par imagerie</term><term>Femelle</term><term>Fibres optiques</term><term>Fluorescence</term><term>Humains</term><term>Hépatectomie</term><term>Laparotomie</term><term>Limite de détection</term><term>Lymphoedème</term><term>Miniaturisation</term><term>Polymères</term><term>Reproductibilité des résultats</term><term>Souris</term><term>Souris nude</term><term>Spectroscopie proche infrarouge</term><term>Transplantation tumorale</term><term>Tumeurs colorectales</term><term>Tumeurs de la tête et du cou</term><term>Tumeurs du foie</term><term>Vert indocyanine</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In laparotomy surgery guided by near-infrared fluorescence imaging, the access to the field of operation is limited by the illumination and/or the imaging field. The side of cavities or organs such as the liver or the heart cannot be examined with the systems available on the market, which are too large and too heavy. In this article, we describe and evaluate a palm sized probe, whose properties, weight, size and sensitivity are adapted for guiding laparotomy surgery. Different experiments have been performed to determine its main characteristics, both on the illumination and imaging sides. The device has been tested for fluorescent molecular probe imaging in preclinical procedures, to prove its ability to be used in cancer nodule detection during surgery. This system is now CE certified for clinical procedures and Indocyanine Green imaging has been performed during clinical investigations: lymphedema and surgical resection of liver metastases of colorectal cancers.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26654116</PMID><DateCreated><Year>2016</Year><Month>02</Month><Day>09</Day></DateCreated><DateCompleted><Year>2016</Year><Month>11</Month><Day>02</Day></DateCompleted><DateRevised><Year>2016</Year><Month>12</Month><Day>30</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1724-191X</ISSN><JournalIssue CitedMedium="Internet"><Volume>32</Volume><Issue>1</Issue><PubDate><Year>2016</Year><Month>Jan</Month></PubDate></JournalIssue><Title>Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)</Title><ISOAbbreviation>Phys Med</ISOAbbreviation></Journal><ArticleTitle>A palm-sized high-sensitivity near-infrared fluorescence imager for laparotomy surgery.</ArticleTitle><Pagination><MedlinePgn>218-25</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.ejmp.2015.11.006</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S1120-1797(15)01025-X</ELocationID><Abstract><AbstractText>In laparotomy surgery guided by near-infrared fluorescence imaging, the access to the field of operation is limited by the illumination and/or the imaging field. The side of cavities or organs such as the liver or the heart cannot be examined with the systems available on the market, which are too large and too heavy. In this article, we describe and evaluate a palm sized probe, whose properties, weight, size and sensitivity are adapted for guiding laparotomy surgery. Different experiments have been performed to determine its main characteristics, both on the illumination and imaging sides. The device has been tested for fluorescent molecular probe imaging in preclinical procedures, to prove its ability to be used in cancer nodule detection during surgery. This system is now CE certified for clinical procedures and Indocyanine Green imaging has been performed during clinical investigations: lymphedema and surgical resection of liver metastases of colorectal cancers.</AbstractText><CopyrightInformation>Copyright © 2015 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Dorval</LastName><ForeName>Paul</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie, UMR 7357, Fédération de Médecine Translationnelle de Strasbourg, Université de Strasbourg/CNRS, 67412 Illkirch, France; Fluoptics, 38040 Grenoble, France. Electronic address: paul.dorval@live.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mangeret</LastName><ForeName>Norman</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Fluoptics, 38040 Grenoble, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Guillermet</LastName><ForeName>Stephanie</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Fluoptics, 38040 Grenoble, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Atallah</LastName><ForeName>Ihab</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Institut Albert Bonniot, U-823, Université Joseph Fourier/INSERM, 38000 Grenoble, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Righini</LastName><ForeName>Christian</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Institut Albert Bonniot, U-823, Université Joseph Fourier/INSERM, 38000 Grenoble, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Barabino</LastName><ForeName>Gabriele</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Centre Hospilato-Universitaire de Saint-Etienne, 42000 Saint-Etienne, France. Electronic address: gabriele.barabino@chu-st-etienne.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Coll</LastName><ForeName>Jean-Luc</ForeName><Initials>JL</Initials><AffiliationInfo><Affiliation>Institut Albert Bonniot, U-823, Université Joseph Fourier/INSERM, 38000 Grenoble, France. Electronic address: jean-luc.coll@ujf-grenoble.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rizo</LastName><ForeName>Philippe</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Fluoptics, 38040 Grenoble, France; CEA-LETI, Minatec, 38054 Grenoble, France. Electronic address: philippe.rizo@fluoptics.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Poulet</LastName><ForeName>Patrick</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie, UMR 7357, Fédération de Médecine Translationnelle de Strasbourg, Université de Strasbourg/CNRS, 67412 Illkirch, France. Electronic address: p.poulet@unistra.fr.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>12</Month><Day>02</Day></ArticleDate></Article><MedlineJournalInfo><Country>Italy</Country><MedlineTA>Phys Med</MedlineTA><NlmUniqueID>9302888</NlmUniqueID><ISSNLinking>1120-1797</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D005456">Fluorescent Dyes</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D011108">Polymers</NameOfSubstance></Chemical><Chemical><RegistryNumber>IX6J1063HV</RegistryNumber><NameOfSubstance UI="D007208">Indocyanine Green</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015179" MajorTopicYN="N">Colorectal Neoplasms</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName><QualifierName UI="Q000601" MajorTopicYN="Y">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003952" MajorTopicYN="N">Diagnostic Imaging</DescriptorName><QualifierName UI="Q000295" MajorTopicYN="N">instrumentation</QualifierName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004867" MajorTopicYN="N">Equipment Design</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005453" MajorTopicYN="N">Fluorescence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005456" MajorTopicYN="N">Fluorescent Dyes</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006258" MajorTopicYN="N">Head and Neck Neoplasms</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName><QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006498" MajorTopicYN="N">Hepatectomy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007208" MajorTopicYN="N">Indocyanine Green</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007813" MajorTopicYN="N">Laparotomy</DescriptorName><QualifierName UI="Q000295" MajorTopicYN="Y">instrumentation</QualifierName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D057230" MajorTopicYN="N">Limit of Detection</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008113" MajorTopicYN="N">Liver Neoplasms</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName><QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName><QualifierName UI="Q000601" MajorTopicYN="Y">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D051379" MajorTopicYN="N">Mice</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008819" MajorTopicYN="N">Mice, Nude</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008904" MajorTopicYN="N">Miniaturization</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009368" MajorTopicYN="N">Neoplasm Transplantation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055100" MajorTopicYN="N">Optical Fibers</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011108" MajorTopicYN="N">Polymers</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015203" MajorTopicYN="N">Reproducibility of Results</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D019265" MajorTopicYN="N">Spectroscopy, Near-Infrared</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D025321" MajorTopicYN="N">Surgery, Computer-Assisted</DescriptorName><QualifierName UI="Q000295" MajorTopicYN="Y">instrumentation</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Fluorescence image-guided surgery</Keyword><Keyword MajorTopicYN="N">Indocyanine green</Keyword><Keyword MajorTopicYN="N">Molecular imaging</Keyword><Keyword MajorTopicYN="N">Near-infrared fluorescence</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2015</Year><Month>09</Month><Day>16</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2015</Year><Month>10</Month><Day>28</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2015</Year><Month>11</Month><Day>17</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>12</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2015</Year><Month>12</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>11</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">26654116</ArticleId><ArticleId IdType="pii">S1120-1797(15)01025-X</ArticleId><ArticleId IdType="doi">10.1016/j.ejmp.2015.11.006</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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