Electrochemotherapy in the treatment of metastatic malignant melanoma: a prospective cohort study by InspECT.
Identifieur interne : 000402 ( PubMed/Curation ); précédent : 000401; suivant : 000403Electrochemotherapy in the treatment of metastatic malignant melanoma: a prospective cohort study by InspECT.
Auteurs : C. Kunte [Allemagne] ; V. Letulé [Allemagne] ; J. Gehl [Danemark] ; K. Dahlstroem [Danemark] ; P. Curatolo [Italie] ; R. Rotunno [Italie] ; T. Muir [Royaume-Uni] ; A. Occhini [Italie] ; G. Bertino [Italie] ; B. Powell [Royaume-Uni] ; W. Saxinger [Autriche] ; G. Lechner [Autriche] ; S-H Liew [Royaume-Uni] ; R. Pritchard-Jones [Royaume-Uni] ; P. Rutkowski [Pologne] ; M. Zdzienicki [Pologne] ; D. Mowatt ; A J Sykes [Royaume-Uni] ; A. Orlando [Royaume-Uni] ; G. Mitsala [Royaume-Uni] ; C R Rossi [Italie] ; L. Campana [Italie] ; M. Brizio [Italie] ; F. De Terlizzi [Italie] ; P. Quaglino [Italie] ; J. Odili [Royaume-Uni]Source :
- The British journal of dermatology [ 1365-2133 ] ; 2017.
Abstract
(ECT) is an effective local treatment for cutaneous metastasis. Treatment involves the administration of chemotherapeutic drugs followed by delivery of electrical pulses to the tumour.
DOI: 10.1111/bjd.15340
PubMed: 28118487
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D. Mowatt<affiliation><nlm:affiliation>Department of Plastic Surgery.</nlm:affiliation><wicri:noCountry code="no comma">Department of Plastic Surgery.</wicri:noCountry></affiliation>Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Electrochemotherapy in the treatment of metastatic malignant melanoma: a prospective cohort study by InspECT.</title><author><name sortKey="Kunte, C" sort="Kunte, C" uniqKey="Kunte C" first="C" last="Kunte">C. Kunte</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology and Allergology, Ludwig-Maximilian University, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology and Allergology, Ludwig-Maximilian University, Munich</wicri:regionArea></affiliation></author><author><name sortKey="Letule, V" sort="Letule, V" uniqKey="Letule V" first="V" last="Letulé">V. Letulé</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology and Allergology, Ludwig-Maximilian University, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology and Allergology, Ludwig-Maximilian University, Munich</wicri:regionArea></affiliation></author><author><name sortKey="Gehl, J" sort="Gehl, J" uniqKey="Gehl J" first="J" last="Gehl">J. Gehl</name><affiliation wicri:level="1"><nlm:affiliation>Center for Experimental Drug and Gene Electrotransfer, Department of Oncology, Copenhagen University Hospital Herlev, Herlev, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Center for Experimental Drug and Gene Electrotransfer, Department of Oncology, Copenhagen University Hospital Herlev, Herlev</wicri:regionArea></affiliation></author><author><name sortKey="Dahlstroem, K" sort="Dahlstroem, K" uniqKey="Dahlstroem K" first="K" last="Dahlstroem">K. Dahlstroem</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plastic Surgery, Copenhagen University Hospital Herlev, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Plastic Surgery, Copenhagen University Hospital Herlev</wicri:regionArea></affiliation></author><author><name sortKey="Curatolo, P" sort="Curatolo, P" uniqKey="Curatolo P" first="P" last="Curatolo">P. Curatolo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology and Plastic Surgery, Dermatologic Clinic, University of Rome 'La Sapienza', Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Dermatology and Plastic Surgery, Dermatologic Clinic, University of Rome 'La Sapienza', Rome</wicri:regionArea></affiliation></author><author><name sortKey="Rotunno, R" sort="Rotunno, R" uniqKey="Rotunno R" first="R" last="Rotunno">R. Rotunno</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology and Plastic Surgery, Dermatologic Clinic, University of Rome 'La Sapienza', Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Dermatology and Plastic Surgery, Dermatologic Clinic, University of Rome 'La Sapienza', Rome</wicri:regionArea></affiliation></author><author><name sortKey="Muir, T" sort="Muir, T" uniqKey="Muir T" first="T" last="Muir">T. Muir</name><affiliation wicri:level="1"><nlm:affiliation>Department of Reconstructive Plastic Surgery, James Cook University Hospital, Middlesbrough, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Reconstructive Plastic Surgery, James Cook University Hospital, Middlesbrough</wicri:regionArea></affiliation></author><author><name sortKey="Occhini, A" sort="Occhini, A" uniqKey="Occhini A" first="A" last="Occhini">A. Occhini</name><affiliation wicri:level="1"><nlm:affiliation>Department of Otolaryngology Head & Neck Surgery, University of Pavia, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Otolaryngology Head & Neck Surgery, University of Pavia, IRCCS Policlinico San Matteo Foundation, Pavia</wicri:regionArea></affiliation></author><author><name sortKey="Bertino, G" sort="Bertino, G" uniqKey="Bertino G" first="G" last="Bertino">G. Bertino</name><affiliation wicri:level="1"><nlm:affiliation>Department of Otolaryngology Head & Neck Surgery, University of Pavia, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Otolaryngology Head & Neck Surgery, University of Pavia, IRCCS Policlinico San Matteo Foundation, Pavia</wicri:regionArea></affiliation></author><author><name sortKey="Powell, B" sort="Powell, B" uniqKey="Powell B" first="B" last="Powell">B. Powell</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plastic Surgery, St George's Hospital, London, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Plastic Surgery, St George's Hospital, London</wicri:regionArea></affiliation></author><author><name sortKey="Saxinger, W" sort="Saxinger, W" uniqKey="Saxinger W" first="W" last="Saxinger">W. Saxinger</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Klinikum Wels-Grieskirchen, Wels, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Dermatology, Klinikum Wels-Grieskirchen, Wels</wicri:regionArea></affiliation></author><author><name sortKey="Lechner, G" sort="Lechner, G" uniqKey="Lechner G" first="G" last="Lechner">G. Lechner</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Klinikum Wels-Grieskirchen, Wels, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Dermatology, Klinikum Wels-Grieskirchen, Wels</wicri:regionArea></affiliation></author><author><name sortKey="Liew, S H" sort="Liew, S H" uniqKey="Liew S" first="S-H" last="Liew">S-H Liew</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plastic Surgery, Whiston Hospital, Prescot, Merseyside, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Plastic Surgery, Whiston Hospital, Prescot, Merseyside</wicri:regionArea></affiliation></author><author><name sortKey="Pritchard Jones, R" sort="Pritchard Jones, R" uniqKey="Pritchard Jones R" first="R" last="Pritchard-Jones">R. Pritchard-Jones</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plastic Surgery, Whiston Hospital, Prescot, Merseyside, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Plastic Surgery, Whiston Hospital, Prescot, Merseyside</wicri:regionArea></affiliation></author><author><name sortKey="Rutkowski, P" sort="Rutkowski, P" uniqKey="Rutkowski P" first="P" last="Rutkowski">P. Rutkowski</name><affiliation wicri:level="1"><nlm:affiliation>Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw</wicri:regionArea></affiliation></author><author><name sortKey="Zdzienicki, M" sort="Zdzienicki, M" uniqKey="Zdzienicki M" first="M" last="Zdzienicki">M. Zdzienicki</name><affiliation wicri:level="1"><nlm:affiliation>Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw</wicri:regionArea></affiliation></author><author><name sortKey="Mowatt, D" sort="Mowatt, D" uniqKey="Mowatt D" first="D" last="Mowatt">D. Mowatt</name><affiliation><nlm:affiliation>Department of Plastic Surgery.</nlm:affiliation><wicri:noCountry code="no comma">Department of Plastic Surgery.</wicri:noCountry></affiliation></author><author><name sortKey="Sykes, A J" sort="Sykes, A J" uniqKey="Sykes A" first="A J" last="Sykes">A J Sykes</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Oncology, Christie Hospital, NHS Foundation Trust, Manchester, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Oncology, Christie Hospital, NHS Foundation Trust, Manchester</wicri:regionArea></affiliation></author><author><name sortKey="Orlando, A" sort="Orlando, A" uniqKey="Orlando A" first="A" last="Orlando">A. Orlando</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plastic and Reconstructive Surgery, Southmead Hospital, North Bristol NHS Trust, Bristol, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Plastic and Reconstructive Surgery, Southmead Hospital, North Bristol NHS Trust, Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Mitsala, G" sort="Mitsala, G" uniqKey="Mitsala G" first="G" last="Mitsala">G. Mitsala</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plastic and Reconstructive Surgery, Southmead Hospital, North Bristol NHS Trust, Bristol, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Plastic and Reconstructive Surgery, Southmead Hospital, North Bristol NHS Trust, Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Rossi, C R" sort="Rossi, C R" uniqKey="Rossi C" first="C R" last="Rossi">C R Rossi</name><affiliation wicri:level="1"><nlm:affiliation>Veneto Institute of Oncology IOV-IRCCS, Padova, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Veneto Institute of Oncology IOV-IRCCS, Padova</wicri:regionArea></affiliation></author><author><name sortKey="Campana, L" sort="Campana, L" uniqKey="Campana L" first="L" last="Campana">L. Campana</name><affiliation wicri:level="1"><nlm:affiliation>Veneto Institute of Oncology IOV-IRCCS, Padova, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Veneto Institute of Oncology IOV-IRCCS, Padova</wicri:regionArea></affiliation></author><author><name sortKey="Brizio, M" sort="Brizio, M" uniqKey="Brizio M" first="M" last="Brizio">M. Brizio</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Sciences, Dermatologic Clinic, University of Torino, Torino, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medical Sciences, Dermatologic Clinic, University of Torino, Torino</wicri:regionArea></affiliation></author><author><name sortKey="De Terlizzi, F" sort="De Terlizzi, F" uniqKey="De Terlizzi F" first="F" last="De Terlizzi">F. De Terlizzi</name><affiliation wicri:level="1"><nlm:affiliation>Scientific and Medical Department, IGEA S.p.A., Carpi, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Scientific and Medical Department, IGEA S.p.A., Carpi</wicri:regionArea></affiliation></author><author><name sortKey="Quaglino, P" sort="Quaglino, P" uniqKey="Quaglino P" first="P" last="Quaglino">P. Quaglino</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Sciences, Dermatologic Clinic, University of Torino, Torino, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medical Sciences, Dermatologic Clinic, University of Torino, Torino</wicri:regionArea></affiliation></author><author><name sortKey="Odili, J" sort="Odili, J" uniqKey="Odili J" first="J" last="Odili">J. Odili</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plastic Surgery, St George's Hospital, London, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Plastic Surgery, St George's Hospital, London</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28118487</idno><idno type="pmid">28118487</idno><idno type="doi">10.1111/bjd.15340</idno><idno type="wicri:Area/PubMed/Corpus">000402</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000402</idno><idno type="wicri:Area/PubMed/Curation">000402</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000402</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Electrochemotherapy in the treatment of metastatic malignant melanoma: a prospective cohort study by InspECT.</title><author><name sortKey="Kunte, C" sort="Kunte, C" uniqKey="Kunte C" first="C" last="Kunte">C. Kunte</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology and Allergology, Ludwig-Maximilian University, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology and Allergology, Ludwig-Maximilian University, Munich</wicri:regionArea></affiliation></author><author><name sortKey="Letule, V" sort="Letule, V" uniqKey="Letule V" first="V" last="Letulé">V. Letulé</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology and Allergology, Ludwig-Maximilian University, Munich, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology and Allergology, Ludwig-Maximilian University, Munich</wicri:regionArea></affiliation></author><author><name sortKey="Gehl, J" sort="Gehl, J" uniqKey="Gehl J" first="J" last="Gehl">J. Gehl</name><affiliation wicri:level="1"><nlm:affiliation>Center for Experimental Drug and Gene Electrotransfer, Department of Oncology, Copenhagen University Hospital Herlev, Herlev, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Center for Experimental Drug and Gene Electrotransfer, Department of Oncology, Copenhagen University Hospital Herlev, Herlev</wicri:regionArea></affiliation></author><author><name sortKey="Dahlstroem, K" sort="Dahlstroem, K" uniqKey="Dahlstroem K" first="K" last="Dahlstroem">K. Dahlstroem</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plastic Surgery, Copenhagen University Hospital Herlev, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Plastic Surgery, Copenhagen University Hospital Herlev</wicri:regionArea></affiliation></author><author><name sortKey="Curatolo, P" sort="Curatolo, P" uniqKey="Curatolo P" first="P" last="Curatolo">P. Curatolo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology and Plastic Surgery, Dermatologic Clinic, University of Rome 'La Sapienza', Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Dermatology and Plastic Surgery, Dermatologic Clinic, University of Rome 'La Sapienza', Rome</wicri:regionArea></affiliation></author><author><name sortKey="Rotunno, R" sort="Rotunno, R" uniqKey="Rotunno R" first="R" last="Rotunno">R. Rotunno</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology and Plastic Surgery, Dermatologic Clinic, University of Rome 'La Sapienza', Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Dermatology and Plastic Surgery, Dermatologic Clinic, University of Rome 'La Sapienza', Rome</wicri:regionArea></affiliation></author><author><name sortKey="Muir, T" sort="Muir, T" uniqKey="Muir T" first="T" last="Muir">T. Muir</name><affiliation wicri:level="1"><nlm:affiliation>Department of Reconstructive Plastic Surgery, James Cook University Hospital, Middlesbrough, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Reconstructive Plastic Surgery, James Cook University Hospital, Middlesbrough</wicri:regionArea></affiliation></author><author><name sortKey="Occhini, A" sort="Occhini, A" uniqKey="Occhini A" first="A" last="Occhini">A. Occhini</name><affiliation wicri:level="1"><nlm:affiliation>Department of Otolaryngology Head & Neck Surgery, University of Pavia, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Otolaryngology Head & Neck Surgery, University of Pavia, IRCCS Policlinico San Matteo Foundation, Pavia</wicri:regionArea></affiliation></author><author><name sortKey="Bertino, G" sort="Bertino, G" uniqKey="Bertino G" first="G" last="Bertino">G. Bertino</name><affiliation wicri:level="1"><nlm:affiliation>Department of Otolaryngology Head & Neck Surgery, University of Pavia, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Otolaryngology Head & Neck Surgery, University of Pavia, IRCCS Policlinico San Matteo Foundation, Pavia</wicri:regionArea></affiliation></author><author><name sortKey="Powell, B" sort="Powell, B" uniqKey="Powell B" first="B" last="Powell">B. Powell</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plastic Surgery, St George's Hospital, London, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Plastic Surgery, St George's Hospital, London</wicri:regionArea></affiliation></author><author><name sortKey="Saxinger, W" sort="Saxinger, W" uniqKey="Saxinger W" first="W" last="Saxinger">W. Saxinger</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Klinikum Wels-Grieskirchen, Wels, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Dermatology, Klinikum Wels-Grieskirchen, Wels</wicri:regionArea></affiliation></author><author><name sortKey="Lechner, G" sort="Lechner, G" uniqKey="Lechner G" first="G" last="Lechner">G. Lechner</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Klinikum Wels-Grieskirchen, Wels, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Dermatology, Klinikum Wels-Grieskirchen, Wels</wicri:regionArea></affiliation></author><author><name sortKey="Liew, S H" sort="Liew, S H" uniqKey="Liew S" first="S-H" last="Liew">S-H Liew</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plastic Surgery, Whiston Hospital, Prescot, Merseyside, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Plastic Surgery, Whiston Hospital, Prescot, Merseyside</wicri:regionArea></affiliation></author><author><name sortKey="Pritchard Jones, R" sort="Pritchard Jones, R" uniqKey="Pritchard Jones R" first="R" last="Pritchard-Jones">R. Pritchard-Jones</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plastic Surgery, Whiston Hospital, Prescot, Merseyside, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Plastic Surgery, Whiston Hospital, Prescot, Merseyside</wicri:regionArea></affiliation></author><author><name sortKey="Rutkowski, P" sort="Rutkowski, P" uniqKey="Rutkowski P" first="P" last="Rutkowski">P. Rutkowski</name><affiliation wicri:level="1"><nlm:affiliation>Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw</wicri:regionArea></affiliation></author><author><name sortKey="Zdzienicki, M" sort="Zdzienicki, M" uniqKey="Zdzienicki M" first="M" last="Zdzienicki">M. Zdzienicki</name><affiliation wicri:level="1"><nlm:affiliation>Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland.</nlm:affiliation><country xml:lang="fr">Pologne</country><wicri:regionArea>Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw</wicri:regionArea></affiliation></author><author><name sortKey="Mowatt, D" sort="Mowatt, D" uniqKey="Mowatt D" first="D" last="Mowatt">D. Mowatt</name><affiliation><nlm:affiliation>Department of Plastic Surgery.</nlm:affiliation><wicri:noCountry code="no comma">Department of Plastic Surgery.</wicri:noCountry></affiliation></author><author><name sortKey="Sykes, A J" sort="Sykes, A J" uniqKey="Sykes A" first="A J" last="Sykes">A J Sykes</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Oncology, Christie Hospital, NHS Foundation Trust, Manchester, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Clinical Oncology, Christie Hospital, NHS Foundation Trust, Manchester</wicri:regionArea></affiliation></author><author><name sortKey="Orlando, A" sort="Orlando, A" uniqKey="Orlando A" first="A" last="Orlando">A. Orlando</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plastic and Reconstructive Surgery, Southmead Hospital, North Bristol NHS Trust, Bristol, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Plastic and Reconstructive Surgery, Southmead Hospital, North Bristol NHS Trust, Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Mitsala, G" sort="Mitsala, G" uniqKey="Mitsala G" first="G" last="Mitsala">G. Mitsala</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plastic and Reconstructive Surgery, Southmead Hospital, North Bristol NHS Trust, Bristol, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Plastic and Reconstructive Surgery, Southmead Hospital, North Bristol NHS Trust, Bristol</wicri:regionArea></affiliation></author><author><name sortKey="Rossi, C R" sort="Rossi, C R" uniqKey="Rossi C" first="C R" last="Rossi">C R Rossi</name><affiliation wicri:level="1"><nlm:affiliation>Veneto Institute of Oncology IOV-IRCCS, Padova, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Veneto Institute of Oncology IOV-IRCCS, Padova</wicri:regionArea></affiliation></author><author><name sortKey="Campana, L" sort="Campana, L" uniqKey="Campana L" first="L" last="Campana">L. Campana</name><affiliation wicri:level="1"><nlm:affiliation>Veneto Institute of Oncology IOV-IRCCS, Padova, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Veneto Institute of Oncology IOV-IRCCS, Padova</wicri:regionArea></affiliation></author><author><name sortKey="Brizio, M" sort="Brizio, M" uniqKey="Brizio M" first="M" last="Brizio">M. Brizio</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Sciences, Dermatologic Clinic, University of Torino, Torino, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medical Sciences, Dermatologic Clinic, University of Torino, Torino</wicri:regionArea></affiliation></author><author><name sortKey="De Terlizzi, F" sort="De Terlizzi, F" uniqKey="De Terlizzi F" first="F" last="De Terlizzi">F. De Terlizzi</name><affiliation wicri:level="1"><nlm:affiliation>Scientific and Medical Department, IGEA S.p.A., Carpi, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Scientific and Medical Department, IGEA S.p.A., Carpi</wicri:regionArea></affiliation></author><author><name sortKey="Quaglino, P" sort="Quaglino, P" uniqKey="Quaglino P" first="P" last="Quaglino">P. Quaglino</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Sciences, Dermatologic Clinic, University of Torino, Torino, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medical Sciences, Dermatologic Clinic, University of Torino, Torino</wicri:regionArea></affiliation></author><author><name sortKey="Odili, J" sort="Odili, J" uniqKey="Odili J" first="J" last="Odili">J. Odili</name><affiliation wicri:level="1"><nlm:affiliation>Department of Plastic Surgery, St George's Hospital, London, U.K.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Plastic Surgery, St George's Hospital, London</wicri:regionArea></affiliation></author></analytic><series><title level="j">The British journal of dermatology</title><idno type="eISSN">1365-2133</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">(ECT) is an effective local treatment for cutaneous metastasis. Treatment involves the administration of chemotherapeutic drugs followed by delivery of electrical pulses to the tumour.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">28118487</PMID><DateCreated><Year>2017</Year><Month>01</Month><Day>24</Day></DateCreated><DateRevised><Year>2017</Year><Month>06</Month><Day>05</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1365-2133</ISSN><JournalIssue CitedMedium="Internet"><Volume>176</Volume><Issue>6</Issue><PubDate><Year>2017</Year><Month>Jun</Month></PubDate></JournalIssue><Title>The British journal of dermatology</Title><ISOAbbreviation>Br. J. Dermatol.</ISOAbbreviation></Journal><ArticleTitle>Electrochemotherapy in the treatment of metastatic malignant melanoma: a prospective cohort study by InspECT.</ArticleTitle><Pagination><MedlinePgn>1475-1485</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1111/bjd.15340</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">(ECT) is an effective local treatment for cutaneous metastasis. Treatment involves the administration of chemotherapeutic drugs followed by delivery of electrical pulses to the tumour.</AbstractText><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">To investigate the effectiveness of ECT in cutaneous metastases of melanoma and to identify factors that affect (beneficially or adversely) the outcome.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Thirteen cancer centres in the International Network for Sharing Practices on Electrochemotherapy consecutively and prospectively uploaded data to a common database. ECT consisted of intratumoral or intravenous injection of bleomycin, followed by application of electric pulses under local or general anaesthesia.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">In total, 151 patients with metastatic melanoma were identified from the database, 114 of whom had follow-up data of 60 days or more. Eighty-four of these patients (74%) experienced an overall response (OR = complete response + partial response). Overall, 394 lesions were treated, of which 306 (78%) showed OR, with 229 showing complete response (58%). In multivariate analysis, factors positively associated with overall response were coverage of deep margins, absence of visceral metastases, presence of lymphoedema and treatment of nonirradiated areas. Factors significantly associated with complete response to ECT treatment were coverage of deep margins, previous irradiation of the treated area and tumour size (< 3 cm). One-year overall survival in this cohort of patients was 67% (95% confidence interval 57-77%), while melanoma-specific survival was 74% (95% confidence interval 64-84%). No serious adverse events were reported, and the treatment was in general very well tolerated.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">ECT is a highly effective local treatment for melanoma metastases in the skin, with no severe adverse effects noted in this study. In the presence of certain clinical factors, ECT may be considered for local tumour control as an alternative to established local treatments, or as an adjunct to systemic treatments.</AbstractText><CopyrightInformation>© 2017 British Association of Dermatologists.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Kunte</LastName><ForeName>C</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Dermatology and Allergology, Ludwig-Maximilian University, Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Letulé</LastName><ForeName>V</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Department of Dermatology and Allergology, Ludwig-Maximilian University, Munich, Germany.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gehl</LastName><ForeName>J</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Center for Experimental Drug and Gene Electrotransfer, Department of Oncology, Copenhagen University Hospital Herlev, Herlev, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dahlstroem</LastName><ForeName>K</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Department of Plastic Surgery, Copenhagen University Hospital Herlev, Denmark.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Curatolo</LastName><ForeName>P</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Dermatology and Plastic Surgery, Dermatologic Clinic, University of Rome 'La Sapienza', Rome, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rotunno</LastName><ForeName>R</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Dermatology and Plastic Surgery, Dermatologic Clinic, University of Rome 'La Sapienza', Rome, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Muir</LastName><ForeName>T</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Department of Reconstructive Plastic Surgery, James Cook University Hospital, Middlesbrough, U.K.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Occhini</LastName><ForeName>A</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Otolaryngology Head & Neck Surgery, University of Pavia, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bertino</LastName><ForeName>G</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Otolaryngology Head & Neck Surgery, University of Pavia, IRCCS Policlinico San Matteo Foundation, Pavia, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Powell</LastName><ForeName>B</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Plastic Surgery, St George's Hospital, London, U.K.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Saxinger</LastName><ForeName>W</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Department of Dermatology, Klinikum Wels-Grieskirchen, Wels, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lechner</LastName><ForeName>G</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Dermatology, Klinikum Wels-Grieskirchen, Wels, Austria.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liew</LastName><ForeName>S-H</ForeName><Initials>SH</Initials><AffiliationInfo><Affiliation>Department of Plastic Surgery, Whiston Hospital, Prescot, Merseyside, U.K.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pritchard-Jones</LastName><ForeName>R</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Plastic Surgery, Whiston Hospital, Prescot, Merseyside, U.K.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rutkowski</LastName><ForeName>P</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zdzienicki</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mowatt</LastName><ForeName>D</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Plastic Surgery.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sykes</LastName><ForeName>A J</ForeName><Initials>AJ</Initials><AffiliationInfo><Affiliation>Department of Clinical Oncology, Christie Hospital, NHS Foundation Trust, Manchester, U.K.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Orlando</LastName><ForeName>A</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Plastic and Reconstructive Surgery, Southmead Hospital, North Bristol NHS Trust, Bristol, U.K.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mitsala</LastName><ForeName>G</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Plastic and Reconstructive Surgery, Southmead Hospital, North Bristol NHS Trust, Bristol, U.K.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rossi</LastName><ForeName>C R</ForeName><Initials>CR</Initials><AffiliationInfo><Affiliation>Veneto Institute of Oncology IOV-IRCCS, Padova, Italy.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Campana</LastName><ForeName>L</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Veneto Institute of Oncology IOV-IRCCS, Padova, Italy.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Brizio</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Medical Sciences, Dermatologic Clinic, University of Torino, Torino, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de Terlizzi</LastName><ForeName>F</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Scientific and Medical Department, IGEA S.p.A., Carpi, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Quaglino</LastName><ForeName>P</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Medical Sciences, Dermatologic Clinic, University of Torino, Torino, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Odili</LastName><ForeName>J</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Plastic Surgery, St George's Hospital, London, U.K.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>InspECT (the International Network for Sharing Practices on Electrochemotherapy)</CollectiveName></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>04</Month><Day>26</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Br J Dermatol</MedlineTA><NlmUniqueID>0004041</NlmUniqueID><ISSNLinking>0007-0963</ISSNLinking></MedlineJournalInfo></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="accepted"><Year>2016</Year><Month>12</Month><Day>21</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>1</Month><Day>25</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>1</Month><Day>25</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>1</Month><Day>25</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28118487</ArticleId><ArticleId IdType="doi">10.1111/bjd.15340</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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