The long term effects of repeated diethylcarbamazine administration with special reference to microfilaraemia and elephantiasis.
Identifieur interne : 006C85 ( PubMed/Corpus ); précédent : 006C84; suivant : 006C86The long term effects of repeated diethylcarbamazine administration with special reference to microfilaraemia and elephantiasis.
Auteurs : F. Partono ; Purnomo ; S. Oemijati ; A. SoewartaSource :
- Acta tropica [ 0001-706X ] ; 1981.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Animals, Blood (parasitology), Brugia, Child, Child, Preschool, Diethylcarbamazine (administration & dosage), Diethylcarbamazine (therapeutic use), Elephantiasis (drug therapy), Female, Filariasis (drug therapy), Filariasis (prevention & control), Humans, Indonesia, Infant, Infant, Newborn, Lymphedema (drug therapy), Male, Microfilariae, Middle Aged, Rural Population.
- MESH :
- chemical , administration & dosage : Diethylcarbamazine.
- drug therapy : Elephantiasis, Filariasis, Lymphedema.
- parasitology : Blood.
- prevention & control : Filariasis.
- chemical , therapeutic use : Diethylcarbamazine.
- Adolescent, Adult, Aged, Animals, Brugia, Child, Child, Preschool, Female, Humans, Indonesia, Infant, Infant, Newborn, Male, Microfilariae, Middle Aged, Rural Population.
Abstract
The result of mass treatment with 50 mg diethylcarbamazine (DEC) per kg body weight followed by two annual selective retreatments in an area highly endemic for Brugia timori infections are described. The criteria for selective re-treatment are simple and practical for use in rural areas. An education programme was developed which focused on describing the relationship between adenolymphangitis and filarial infections, the danger of repeated attacks and the efficiency of DEC in eliminating these attacks. Motivated persons in the community were charged with the responsibility of promptly treating all cases with acute clinical manifestations. With this programme the microfilaria rate by finger prick decreased from 24% to 0%, and by Nuclepore filtration from 30% to 5%. The adenolymphangitis rate decreased from 46% to 11% and the "elephantiasis' rate from 17% to 4%.
PubMed: 6118029
Links to Exploration step
pubmed:6118029Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The long term effects of repeated diethylcarbamazine administration with special reference to microfilaraemia and elephantiasis.</title>
<author><name sortKey="Partono, F" sort="Partono, F" uniqKey="Partono F" first="F" last="Partono">F. Partono</name>
</author>
<author><name sortKey="Purnomo" sort="Purnomo" uniqKey="Purnomo" last="Purnomo">Purnomo</name>
</author>
<author><name sortKey="Oemijati, S" sort="Oemijati, S" uniqKey="Oemijati S" first="S" last="Oemijati">S. Oemijati</name>
</author>
<author><name sortKey="Soewarta, A" sort="Soewarta, A" uniqKey="Soewarta A" first="A" last="Soewarta">A. Soewarta</name>
</author>
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<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="1981">1981</date>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">The long term effects of repeated diethylcarbamazine administration with special reference to microfilaraemia and elephantiasis.</title>
<author><name sortKey="Partono, F" sort="Partono, F" uniqKey="Partono F" first="F" last="Partono">F. Partono</name>
</author>
<author><name sortKey="Purnomo" sort="Purnomo" uniqKey="Purnomo" last="Purnomo">Purnomo</name>
</author>
<author><name sortKey="Oemijati, S" sort="Oemijati, S" uniqKey="Oemijati S" first="S" last="Oemijati">S. Oemijati</name>
</author>
<author><name sortKey="Soewarta, A" sort="Soewarta, A" uniqKey="Soewarta A" first="A" last="Soewarta">A. Soewarta</name>
</author>
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<series><title level="j">Acta tropica</title>
<idno type="ISSN">0001-706X</idno>
<imprint><date when="1981" type="published">1981</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Animals</term>
<term>Blood (parasitology)</term>
<term>Brugia</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Diethylcarbamazine (administration & dosage)</term>
<term>Diethylcarbamazine (therapeutic use)</term>
<term>Elephantiasis (drug therapy)</term>
<term>Female</term>
<term>Filariasis (drug therapy)</term>
<term>Filariasis (prevention & control)</term>
<term>Humans</term>
<term>Indonesia</term>
<term>Infant</term>
<term>Infant, Newborn</term>
<term>Lymphedema (drug therapy)</term>
<term>Male</term>
<term>Microfilariae</term>
<term>Middle Aged</term>
<term>Rural Population</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Diethylcarbamazine</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Elephantiasis</term>
<term>Filariasis</term>
<term>Lymphedema</term>
</keywords>
<keywords scheme="MESH" qualifier="parasitology" xml:lang="en"><term>Blood</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Filariasis</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Diethylcarbamazine</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Animals</term>
<term>Brugia</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Female</term>
<term>Humans</term>
<term>Indonesia</term>
<term>Infant</term>
<term>Infant, Newborn</term>
<term>Male</term>
<term>Microfilariae</term>
<term>Middle Aged</term>
<term>Rural Population</term>
</keywords>
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<front><div type="abstract" xml:lang="en">The result of mass treatment with 50 mg diethylcarbamazine (DEC) per kg body weight followed by two annual selective retreatments in an area highly endemic for Brugia timori infections are described. The criteria for selective re-treatment are simple and practical for use in rural areas. An education programme was developed which focused on describing the relationship between adenolymphangitis and filarial infections, the danger of repeated attacks and the efficiency of DEC in eliminating these attacks. Motivated persons in the community were charged with the responsibility of promptly treating all cases with acute clinical manifestations. With this programme the microfilaria rate by finger prick decreased from 24% to 0%, and by Nuclepore filtration from 30% to 5%. The adenolymphangitis rate decreased from 46% to 11% and the "elephantiasis' rate from 17% to 4%.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">6118029</PMID>
<DateCreated><Year>1982</Year>
<Month>01</Month>
<Day>20</Day>
</DateCreated>
<DateCompleted><Year>1982</Year>
<Month>01</Month>
<Day>20</Day>
</DateCompleted>
<DateRevised><Year>2016</Year>
<Month>11</Month>
<Day>23</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0001-706X</ISSN>
<JournalIssue CitedMedium="Print"><Volume>38</Volume>
<Issue>3</Issue>
<PubDate><Year>1981</Year>
<Month>Sep</Month>
</PubDate>
</JournalIssue>
<Title>Acta tropica</Title>
<ISOAbbreviation>Acta Trop.</ISOAbbreviation>
</Journal>
<ArticleTitle>The long term effects of repeated diethylcarbamazine administration with special reference to microfilaraemia and elephantiasis.</ArticleTitle>
<Pagination><MedlinePgn>217-25</MedlinePgn>
</Pagination>
<Abstract><AbstractText>The result of mass treatment with 50 mg diethylcarbamazine (DEC) per kg body weight followed by two annual selective retreatments in an area highly endemic for Brugia timori infections are described. The criteria for selective re-treatment are simple and practical for use in rural areas. An education programme was developed which focused on describing the relationship between adenolymphangitis and filarial infections, the danger of repeated attacks and the efficiency of DEC in eliminating these attacks. Motivated persons in the community were charged with the responsibility of promptly treating all cases with acute clinical manifestations. With this programme the microfilaria rate by finger prick decreased from 24% to 0%, and by Nuclepore filtration from 30% to 5%. The adenolymphangitis rate decreased from 46% to 11% and the "elephantiasis' rate from 17% to 4%.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Partono</LastName>
<ForeName>F</ForeName>
<Initials>F</Initials>
</Author>
<Author ValidYN="Y"><LastName>Purnomo</LastName>
</Author>
<Author ValidYN="Y"><LastName>Oemijati</LastName>
<ForeName>S</ForeName>
<Initials>S</Initials>
</Author>
<Author ValidYN="Y"><LastName>Soewarta</LastName>
<ForeName>A</ForeName>
<Initials>A</Initials>
</Author>
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<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
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<MedlineJournalInfo><Country>Netherlands</Country>
<MedlineTA>Acta Trop</MedlineTA>
<NlmUniqueID>0370374</NlmUniqueID>
<ISSNLinking>0001-706X</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>V867Q8X3ZD</RegistryNumber>
<NameOfSubstance UI="D004049">Diethylcarbamazine</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName>
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<MeshHeading><DescriptorName UI="D001769" MajorTopicYN="N">Blood</DescriptorName>
<QualifierName UI="Q000469" MajorTopicYN="Y">parasitology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002009" MajorTopicYN="N">Brugia</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002675" MajorTopicYN="N">Child, Preschool</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004049" MajorTopicYN="N">Diethylcarbamazine</DescriptorName>
<QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName>
<QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004604" MajorTopicYN="N">Elephantiasis</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005368" MajorTopicYN="N">Filariasis</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName>
<QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007214" MajorTopicYN="N">Indonesia</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007223" MajorTopicYN="N">Infant</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007231" MajorTopicYN="N">Infant, Newborn</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008842" MajorTopicYN="N">Microfilariae</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012424" MajorTopicYN="N">Rural Population</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
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